3 Matching Annotations
  1. Last 7 days
  2. accessmedicine.mhmedical.com accessmedicine.mhmedical.com
    Superior Vena Caval Obstruction
    1
    1. Arshadbhat 05 Apr 2026
      Urgent treatment for neoplasm consists of (1) cautious use of intravenous diuretics and (2) mediastinal irradiation, starting within 24 hours, with a treatment plan designed to give a high daily dose of radiation but a short total course of therapy to rapidly shrink the local tumor. Intensive radiation therapy combined with chemotherapy will palliate the process in up to 90% of patients. In patients with a subacute presentation, radiation therapy alone usually suffices. Chemotherapy is added if lymphoma or small-cell carcinoma is diagnosed

      endovascular stenting emerging as first-line therapy for rapid symptom relief, while definitive treatment targets the underlying cause

      Glucocorticoids (dexamethasone 4 mg every 6 hours) are commonly prescribed but lack robust supporting data; they may be more beneficial in lymphoma or thymoma and as prophylaxis against radiation-induced edema. [2-4] Importantly, SVC syndrome is no longer considered a medical emergency except in rare cases with life-threatening cerebral edema, laryngeal edema, or altered mental status. When thrombosis is present, catheter-directed thrombolysis or aspiration thrombectomy should be performed within 2-5 days of symptom onset before thrombus organization occurs. [3] The role of long-term anticoagulation after stenting remains unclear, though it is standard when significant thrombosis is present The American College of Chest Physicians recommends obtaining histologic diagnosis before treatment in suspected lung cancer cases, as stenting does not interfere with tissue diagnosis. [2] For small cell lung cancer (SCLC), chemotherapy alone is recommended as first-line treatment given rapid response rates. [2] For non-small cell lung cancer (NSCLC), radiation therapy and/or stent insertion are recommended, with response rates of 59% for chemotherapy and 63% for radiation therapy. [2] Patients with chemotherapy- or radiation-refractory disease should receive vascular stents For device-related thrombosis (catheters, pacemakers), catheter removal should be considered in conjunction with anticoagulation. [4] Endovascular therapy is first-line for device-related obstruction, while surgical bypass may be preferred for mediastinal fibrosis. [7] Both approaches show good mid-term patency, though secondary interventions are common (approximately 27-28%
    Visit annotations in context

    Tags

    Annotators

    URL

    accessmedicine.mhmedical.com/content.aspx
  3. Nov 2023
  4. docdrop.org docdrop.org
    Video: Conversation between Adam Omary, Roy Baumeister, and Michael Levin (DocDrop)
    1
    1. stopresetgo 07 Nov 2023
      this is a cancer uh approach that we work on which is to not to kill those cells but to force them to re reconnect to their neighbors and when they reconnect to the 00:31:24 neighbors they once again become part of the collective that's working on making nice skin nice muscle they stop being metastatic and they they go back

      • for: quote - Michael Levin, quote - MET of individuality, quote - memory wipe, quote - cancer therapy - MET of individuality

      • quote: Michael Levin

        • this is a cancer approach that we work on which is to not to kill those cells but to force them to re reconnect to their neighbors and when they reconnect to the neighbors they once again become part of the collective that's working on making nice skin nice muscle they stop being metastatic and they they go back

      • comment

        • Michael refers to cancer as a "memory wipe" where they have forgotten the normative programmed narrative of bodily / collective / multicellular unity
      quote - Michael Levin quote - MET of individuality quote - memory wipe - cancer quote - cancer therapy - MET of Individuality memory wipe MET of Individuality - cancer therapy cancer therapy - evolutionary approach
    Visit annotations in context

    Tags

    Annotators

    URL

    docdrop.org/video/UfoVTA0ilsY/
  5. Jan 2022
  6. www.biorxiv.org www.biorxiv.org
    Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain
    1
    1. lucyparfitt16 11 Jan 2022

      Fernandez-Castaneda, A., Lu, P., Geraghty, A. C., Song, E., Lee, M.-H., Wood, J., Yalcin, B., Taylor, K. R., Dutton, S., Acosta-Alvarez, L., Ni, L., Contreras-Esquivel, D., Gehlhausen, J. R., Klein, J., Lucas, C., Mao, T., Silva, J., Pena-Hernandez, M., Tabachnikova, A., … Monje, M. (2022). Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain (p. 2022.01.07.475453). https://doi.org/10.1101/2022.01.07.475453

      is:preprint lang:en COVID-19 neurological symptoms attention concentration information processing memory long covid cognition cognitive impairment brain neurogenesis cancer therapy
    Visit annotations in context

    Tags

    Annotators

    URL

    biorxiv.org/content/10.1101/2022.01.07.475453v1