Luban, J., Sattler, R., Mühlberger, E., Graci, J. D., Cao, L., Weetall, M., Trotta, C., Colacino, J. M., Bavari, S., Strambio-De-Castillia, C., Suder, E. L., Wang, Y., Soloveva, V., Cintron-Lue, K., Naryshkin, N. A., Pykett, M., Welch, E. M., O’Keefe, K., Kong, R., … Peltz, S. (2020). The DHODH Inhibitor PTC299 Arrests SARS-CoV-2 Replication and Suppresses Induction of Inflammatory Cytokines. BioRxiv, 2020.08.05.238394. https://doi.org/10.1101/2020.08.05.238394
3 Matching Annotations
- Aug 2020
-
- May 2018
-
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
-
One group received citalopram (up to 60 mg/day) plus vitamin C (up to 1,000 mg/day). The other group received citalopram plus placebo.
Considering the results of other trials with different depression severities and vitamin C dosage and forms (sustained release) (covered in this article), it is astonishing that the researchers used such a single, modest, non-sustained release dose.
The plasma peak of vitamin C is obtained a few hours after the administration. For the rest of the day, the subject is back to baseline.
This is common knowledge.
-
- Mar 2018
-
juvenon.com juvenon.com
-
The pharmacokinetics of Alcar are complex,similar to other naturally occurring substances andinclude partial prehepatic metabolism, first liver passeffect and varying bioavailability
The pharmacokinetics of alcar
-