it suggests that maybe these prefrontal regionsthat are really important for decision making have to work a little bit harder when we decidenot to cooperate when we decide to compete or defect at the expense of the other person.

we experience pleasurewhen we cooperate knowing that our cooperation is going to lead to benefits to the peoplethat we’re cooperating with.

they found that reward signalling increased with reciprocated cooperation, inother words if I cooperate and I learn that you have alsocooperated then we’re both benefitting from this mutual cooperation there is greater rewardactivation or reward signalling gets boosted. And then also they found that when peoplecooperate but then are met with not cooperation in other words, unreciprocated cooperationdecreases activation in these reward processing areas.

suggest that lonely people have significantly more trouble bouncing back from life’s stresses and strains. For instance, lonely and non-lonely college students in their study reported similar daily activities, but lonely college students experienced more stress in those activities. Among older adults, lonely individuals said they felt more helpless and threatened than did non-lonely people. What’s more, higher stress levels were associated with worse health: Lonely college students had higher blood pressure than non-lonely ones, putting them at greater risk for heart disease, and this health disparity was even greater between lonely and non-lonely older adults. Plus, Hawkley and Cacioppo found that these lonely older adults had higher levels of stress-related hormones, such as cortisol and epinephrine, which may weaken the immune system over time.

Giving has also been linked to the release of oxytocin, a hormone (also released during sex and breast feeding) that induces feelings of warmth, euphoria, and connection to others. In laboratory studies, Paul Zak, the director of the Center for Neuroeconomics Studies at Claremont Graduate University, has found that a dose of oxytocin will cause people to give more generously and to feel more empathy towards others,

warm, sensitive parenting for three year olds predicts greater focused concentration in the children one year later—which in turn predicts greater sympathy at ages six and seven. Vagal tone in the kids at three years also predicts sympathy three and four years later. As was the case for parenting style, the Vagal tone effect was largely related to the children’s concentration skills as four years olds.  Together, these data suggest that warm, sensitive, authoritative parenting may support skills like managing emotions and focusing attention, and that children with higher Vagal tone are more likely to have these skills, which in turn paves the way for sympathy for other peoples’ suffering.

Dacher spoke about the Vagus nerve and its role in social connection and, in turn, happiness. In the essay below, Emiliana summarizes very recent research showing that Vagal tone, an index of the general strength of influence that a person's Vagus nerve has on their heart, predicts the emergence of sympathetic behavior over development--and further, that in college students, experiencing compassion actually engages the Vagus nerve. 

Pride doesn’t illicit and upregulation of vagal tone, pride instead causes very littlechange because again pride is self-focused as opposed to focused on others.

people who are feeling compassion engage their vagus system.

Recent neuroscience studies suggest that positive emotions are less heritable—that is, less determined by our DNA—than the negative emotions. Other studies indicate that the brain structures involved in positive emotions like compassion are more “plastic”—subject to changes brought about by environmental input.

Taken together, our strands of evidence suggest the following. Compassion is deeply rooted in human nature; it has a biological basis in the brain and body. Humans can communicate compassion through facial gesture and touch, and these displays of compassion can serve vital social functions, strongly suggesting an evolutionary basis of compassion. And when experienced, compassion overwhelms selfish concerns and motivates altruistic behavior.

Remarkably, people in these experiments reliably identified compassion, as well as love and the other ten emotions, from the touches to their forearm. This strongly suggests that compassion is an evolved part of human nature—something we’re universally capable of expressing and understanding.

breastfeeding and massages elevate oxytocin levels in the blood (as does eating chocolate). In some recent studies I’ve conducted, we have found that when people perform behaviors associated with compassionate love—warm smiles, friendly hand gestures, affirmative forward leans—their bodies produce more oxytocin. This suggests compassion may be self-perpetuating: Being compassionate causes a chemical reaction in the body that motivates us to be even more compassionate.

helping others brings the same pleasure we get from the gratification of personal desire.

What is the ANS profile of compassion? As it turns out, when young children and adults feel compassion for others, this emotion is reflected in very real physiological changes: Their heart rate goes down from baseline levels, which prepares them not to fight or flee, but to approach and soothe.

Evolutionary biologists like Frans de Waal have shown that we are social animals who have naturally evolved to care for each other, just like our primate cousins. And psychologists have revealed that we are primed for empathy by strong attachment relationships in the first two years of life.  But empathy doesn’t stop developing in childhood. We can nurture its growth throughout our lives—and we can use it as a radical force for social transformation.

We rely more on what we feel than what we think when solving moral dilemmas. It’s not that religion and culture don’t have a role to play, but the building blocks of morality clearly predate humanity. We recognize them in our primate relatives, with empathy being most conspicuous in the bonobo ape and reciprocity in the chimpanzee. Moral rules tell us when and how to apply our empathic tendencies, but the tendencies themselves have been in existence since time immemorial.

Bonobos are less brutal, but in their case, too, empathy needs to pass through several filters before it will be expressed. Often, the filters prevent expressions of empathy because no ape can afford feeling pity for all living things all the time. This applies equally to humans. Our evolutionary background makes it hard to identify with outsiders. We’ve evolved to hate our enemies, to ignore people we barely know, and to distrust anybody who doesn’t look like us. Even if we are largely cooperative within our communities, we become almost a different animal in our treatment of strangers.

Within a bottom-up framework, the focus is not so much on the highest levels of empathy, but rather on its simplest forms, and how these combine with increased cognition to produce more complex forms of empathy. How did this transformation take place? The evolution of empathy runs from shared emotions and intentions between individuals to a greater self/other distinction—that is, an “unblurring” of the lines between individuals. As a result, one’s own experience is distinguished from that of another person, even though at the same time we are vicariously affected by the other’s. This process culminates in a cognitive appraisal of the other’s behavior and situation: We adopt the other’s perspective.

Having descended from a long line of mothers who nursed, fed, cleaned, carried, comforted, and defended their young, we should not be surprised by gender differences in human empathy, such as those proposed to explain the disproportionate rate of boys affected by autism, which is marked by a lack of social communication skills.

Consolation is defined as friendly or reassuring behavior by a bystander toward a victim of aggression. For example, chimpanzee A attacks chimpanzee B, after which bystander C comes over and embraces or grooms B. Based on hundreds of such observations, we know that consolation occurs regularly and exceeds baseline levels of contact. In other words, it is a demonstrable tendency that probably reflects empathy, since the objective of the consoler seems to be to alleviate the distress of the other. In fact, the usual effect of this kind of behavior is that it stops screaming, yelping, and other signs of distress.

rhesus monkeys refused to pull a chain that delivered food to themselves if doing so gave a shock to a companion. One monkey stopped pulling the chain for 12 days after witnessing another monkey receive a shock. Those primates were literally starving themselves to avoid shocking another animal.

This capacity likely evolved because it served our ancestors’ survival in two ways. First, like every mammal, we need to be sensitive to the needs of our offspring. Second, our species depends on cooperation, which means that we do better if we are surrounded by healthy, capable group mates. Taking care of them is just a matter of enlightened self-interest.

people may have an inborn biological propensity to be more sensitive to social input, and still learn when, how, and where to use this ability from life experience.

There’s neuroscientifc studies thatshow that when people play games together and earn an award, there’s a greateractivation of their dopamine reward circuitry than when they earn that same awardon their own.

differentiate something called empathic concern from something called empathicdistress and what it turns out is that empathic concern is associated with all kindsof benefits people who experience empathic concern are more likely to help, they’rebetter at regulating their own emotions they’re more stable and socially functionalin life whereas people who experience empathic distress have other issues andstruggles that we can flesh out in later weeks. The interesting thing about thisbody of work is that it anticipates are next week of material which will be aboutcompassion and compassion is really what elevates empathy from the potential forempathic distress

So when we look at what happens inthe brain, when people are viewing images of other people in pain what we see is aspecific set of structures that systematically represent that state of being moved bythatso the activation is typically in the interior insula and the medial prefrontal corticesand the insula is important for representing visceral activation so once again yoursadness or your pain or your suffering causes me to get aroused something happensin my body in response to that and my midline activation is typically implicatedin being concerned or trying to understand what that means like what is it to mewhat is this feeling that I’m having in my body usually mean? And those are themechanisms that are involved in affective empathy. Cognitive empathy involvesa wider range of structures, distributed around the cerebral cortex and they’reinvolved in visual expertise and again a self referential knowledge, what is thisparticular moment mean related to my memories about the world or my historicknowledge. So there are separate structures separate systems that are involved inthese two different ways that we can learn to know other people.

Think of taking a yoga class or a dance class. If you had to do this with the teachersimply explaining step by step verbally what to do it would be much morechallenging than it is when the teacher actually demonstrates it physically andthat’s precisely because of your mirror neurons that are helping you simulate andrepresent that motion prior to actually trying to do it.

shown when you block ones ability tomimic a face a facial expression of somebody that’s in front of them by having them,say, bite on a pencil so they can’t use their facial muscles in a spontaneous way,they’re not as good at recognizing the expressions that they see.

When you especially resonate with someone else, the two of you are quite literally on the same wavelength, biologically. True connection is one of love’s bedrock prerequisites—and a prime reason that love is not unconditional. True connection is physical and unfolds in real time; it is neither abstract nor mediated. It requires a sensory and temporal co-presence of bodies.

found time andtime again if I have really rich patterns of friendships I feel less stress on a dailybasis I have lower levels of he stress hormone cortisol so its starting to affect ourstress profiles

and what we know is tight connections tofriends are one of the great determinants of happiness and health. The strongerthe networks of friends that we have the greater the happiness and well being weenjoy in just about every part of the world. We know that strong friendships areassociated with better health profiles.

influential theorizing that I want you to be mindful of of Shelley Taylor, showing thatour tendencies toward friendship and connection activate oxytocin and counteractthe responses of stress so we start to get a picture of why friendships matter.

If we have evidence that someone is deceiving us, we can withdraw trust and resources no matter how high we are on oxytocin. If we think someone doesn’t have our best interests at heart, we can end the relationship with a person or a group. But the effects go beyond self-interest. We may like being part of a group so much that we’re willing to hurt others just to stay in it. The desire to belong can compromise our ethical and empathic instincts. That’s when the conscious mind needs to come online and put the brakes on the pleasures of social affliliation.

increased oxytocin did not predict where they donated their money. But there are some caveats. The more marginalized a group felt on campus, the more likely they were to circle their wagons and favor their own in-group (presumably, the band nerds weren’t as generous as frat boys to other groups). The effects of oxytocin could also change depending on what else was happening in the body: If Zak’s lab induced stress or acted to jack up testosterone, participants could, in fact, become more aggressive toward out-groups.

oxytocin is involved with attachment and social bonding, but that neural system can get tangled up in fear and anxiety—it gives us a visceral memory of those who have harmed us, as well as those who have cared for us.

oxytocin doesn’t simply make you all lovey-dovey, suggests this study. It also keeps you faithful to your partner—and wary of her rivals.

Each group watched a series of images and the individuals in the group voted for which ones they found most attractive. The results: The oxytocin-influenced participants tended to go with the flow of their group, while the placebo-dosed participants hewed to their own individualistic path. The implication: Oxytocin is great when you’re out with friends or solving a problem with coworkers. It might not be so great when you need to pick a leader or make some other big decision that requires independence, not conformity.

oxytocin doesn’t just bond us to mothers, lovers, and friends—it also seems to play a role in excluding others from that bond. (And perhaps, as one scientist has argued, wanting what other people have.) This just makes oxytocin more interesting—and it points to a fundamental, constantly recurring fact about human beings: Many of the same biological and psychological mechanisms that bond us together can also tear us apart. It all depends on the social and emotional context.

“The narrow thinking that medications are the only way to control persistent pain,” Dr. Arnstein concluded, “has resulted in a lot of suffering.” Researchers have discovered a physiological basis for the warm glow that often seems to accompany giving. “The benefits of giving back are definitely biological,” says bioethicist Stephen G. Post, co-author of Why Good Things Happen to Good People. “Contemporary neuroscience has confirmed the connection between the physiological and psychological. We know now that the stress response, hormones, and even the immune system are impacted by, and impact, the pathways in the brain. MRI studies of the participants’ brains revealed that making a donation activated the mesolimbic pathway—the brain’s reward center.”