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In the Seventies, the evolutionary-biological approach to the study of human behavior grew even more popular. Its leading exponents were Hamilton’s Oxford colleague Richard Dawkins—who has called Hamilton “the greatest Darwinian of my lifetime”—and the Harvard entomologist E. O. Wilson, who recalled his imagination being “captured” by Lorenz at a pivotal point in his graduate studies.
Dawkins and Wilson both influenced by W. D. Hamilton
W. D. Hamilton, one of the most influential evolutionary biologists of the second half of the twentieth century. Hamilton helped develop new theoretical tools that allowed scientists to postulate a genetic basis for a range of complex social behaviors. Among these behaviors, in Hamilton’s view, was genocide, which was a natural if morally regrettable response to population growth among a competing “tribe.”
we steal everything from neuroscience. All the tools both the bench tools and the conceptual stuff we we take directly from uh from what the neuroscientists do and every and everything works works very well.
for - adjacency - neuroscience - development biology - neuroscience tools apply to both - Michael Levin
His main hypothesis, that bioelectric gradients serve as prepatterns guiding morphogenesis, has been confirmed using modern molecular physiology, as have his ideas about the place of cancer and the nervous system in the question of biological organization. With limited technology but deep insight, he derived insights that anticipated many modern discoveries. Even more importantly, Burr’s view of bioelectricity as a convenient entry point for rigorous investigation of the broader question of self-organizing properties of life highlights a frontier of inquiry that awaits today’s researchers.
A lot of bright minds have been silenced by established authorities, particularly in medicine, where people's life are at stake, hence professor acquire semi-god powers.
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Theupholstery and the rugs muffle her but we can hear her clearly despite that.The tension between her lack of control and her attempt to suppress it ishorrible. It's like a fart in church.
Serena Joy's muffling cries symbolise the real comparative and biologically sinful nature of the act, that everyone else is awkwardly yet restraining to ignore. The "fart in church" really indicates a biological necessity, a response to a strict and man-made construct such as the church.
Harmonic Cosmic Ecology (HCE) 7.4 proposes a unified framework where gravitational behavior emerges from quantum informational delays within resonant qubit lattices, integrating cosmology, biology, and technology. Anchored by the Informational Gravity Hypothesis (IGH), it quantifies structure and coherence across scales—from cellular vibrations (~10⁶ Hz) to galactic black holes (~10⁻³ Hz)—via a Universal Emergence Function. Supported by empirical tests (e.g., gravitational Aharonov-Bohm effect, black hole QPOs), HCE 7.4 challenges traditional paradigms, suggesting life and technology can align with cosmic harmonics. This version offers testable predictions for Hubble/Webb data, NV-center experiments, and industrial applications, framing a resonant universe where stability hinges on harmonic interplay. Open for annotation—seeking feedback on resonance models, calibration, and interdisciplinary implications.
for - book - The Biology of Desire - 2015 - Marc Lewis - from - youtube - How the Meaning Crisis is related to the Drug Crisis - John Vervaeke - https://hyp.is/DcNL3PW7Ee-Qq6P6Ct5-YQ/www.youtube.com/watch?v=Y-c2E5FB5Z4
the book I tell the story of Five addicts um one is a heroin addict one's a meth addict one was addicted to pharmaceutical uh opiates um the fourth one was a British man who was an alcoholic very serious alcoholic and the fifth one was an eating disordered person
> for - book - The Biology of Desire - Why Addiction is not a Disease - 2015 Marc Lewis - https://dl.icdst.org/pdfs/files4/2a48405faa052ec2b4e0c56a79e001ca.pdf
what we want in our bodies is a mind melt of cells that cells forget about their own little ego and start identifying with a larger Collective of the organ and the way cells do that is through bioelectricity it is what Michael Levan calls a cognitive glue
for - multi-scale competency architecture - groups of individuals coalesce into an individual at a higher level - SOURCE - Youtube - Bioelectric fields: A Paradigm Shift in Biology - Michael Levin - 2025, Jan
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RP4 plasmid (also known as RK2, RP1, and the Birmingham plasmid) stands not only as a model of bacterial conjugation studied over the past 40 years, but also as one of the most conspicuous, broad-host range conjugative plasmids described in the literature. It mediates mating and plasmid transfer between a wide variety of Gram– donors/recipients (8) and is also capable of efficiently conjugating with Gram+, (9) yeast (10,11) and mammalian cells. (12)
Some conjugation systems, such as IncF, IncH, and IncI plasmids, transfer DNA efficiently in liquid media, while others, including the IncN, IncM, IncP, and IncW plasmids, achieve higher DNA transfer frequencies on solid media [28]. It is suspected that the ability to transfer DNA in different environmental conditions is related to variation in pilus formation, structure, and stability of cells during the conjugation process.
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I think the vican barrier is not any longer a barrier
for - evolutionary biology - Weissman barrier - refuted by modern research - Denis Noble
accumulation of all of that movement of charge is contributing to that electrical phenomenon and therefore in the end what you're doing is talking about a higher level of causation U than the components of the cell
for - evolutionary biology - Denis Noble - journey from reductionist to non-reductionist - ion channel and cell membrane work - connects to bioelectricity in the entire body
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for - evolutionary biology - human culture - why it is dominant - openendedness
summary - the claim of this paper is that culture is not something unique to humans, but what is is - our open-ended understanding of the world that allows us to fractally nest many different subtasks.
example
for - example - evolutionary biology - openendedness - making breakfast
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Simply let the stress be leaky so if the cell out here that's that's stressed out all it has to do is release some of that some of those stress molecules in this case like literally molecules that are that serve as signals of how systemic level stress and the cells around it now they're stressed out and they're it's it's not that they're altruistic it's just that um their plasticity goes up where they start to move around and to be a little more willing to do new things then the cell gets to where it's going then everybody's stress drops
for - crisis management - cellular biology example - Michael Levin
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Annotate, do not highlight. Do not select "post to only me" because no one else will see it.
Annotating the syllabus allows you to identify questions and clarify course expectations, in addition to practicing using the annotation tool.
Biology is the scientific study of life.
Biology is the study of life and living organisms, encompassing everything from the smallest microorganisms to the largest ecosystems. It's a field that reveals the intricate processes that sustain life, offering insights into the complexity of the natural world and the interdependence of all living things.
on land, we use net primary production as an indicator for biodiversity, so basically, the richness of all biomass on land, but the ocean is also a control variable. a massive food web of net primary production from phytoplankton to the, you know, the big sharks and whales. And, we, we, need to be able to, represent scientifically what are the, minimum levels of keeping intact food webs in the ocean to keep the ocean functioning. Oxygen levels, as you mentioned as well,
for - planetary boundaries - ocean biology - net primary production
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critique on classic physics and its deductive methods and focus on isolated phenomena. Bertalanffy considered such methods as unsuitable for biology
genetics
Everywhere this term appears below, please also consider the lack of language to describe genesis as a whole:
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I started to use in the 00:58:01 little book the music of Life a way of exploring that metaphor
for - follow up - book - The Music of Life - Biology Beyond Genes
to - book - The Music of Life - Biology Beyond Genes - https://hyp.is/OI8RVBYIEe-t-rObPCPKoQ/www.univ.ox.ac.uk/book/the-music-of-life-biology-beyond-genes/
I think one of the other mistakes that have been made in biology of the 20th century was
for - individual / collective gestalt - gene centrism - paradigm shift - adjacency - mistake of 20th century biology - reductionism - separating organism from environment - individual / collective gestalt, individual / environment gestalt - quote - mistake of 20th century biology - Ray Noble - key insight - mistake of 20th century biology- Ray Noble
quote - mistake of 20th century biology - Ray Noble - (see below)
adjacency - mistake of 20th century biology - between - reductionism - separating organism from environment - individual / collective gestalt, - individual / environment gestalt - adjacency relationship - The mistake that 20th century biology has made is in - ascribing too much power to the gene, and - minimizing the role of epigenetics - Focusing the majority of attention and resources on the genes of the organism, and - defocusing attention on the organisms (epigenetic) interactions with the environment, including both - biotic elements and - abiotic elements - It's not the case that the genes are the major determinant factor and the epigenetics play a minor role - It IS the case that epigenetics play an equally important role in transmitting and assimilating features into the genome - The individual organism is intertwingled with its environment and with other living organisms - The individual / collective gestalt and the individual / environment gestalt is the appropriate unit of study
there is a neuron in a seans that responds to temperature and if you take a normal temperature worm 00:36:26 and you put it in high temperature
for - paradigm shift - evolutionary biology - epigenetic's critical role in inheritance - experimental proof - C. Elegan - Oded Rechavi
Ray emphasized this answer which is very usual well epigenetic inheritance only goes on for a generation or two no
for - explanation - evolutionary biology - neo-darwinian mistake - view of epigenetic inheritance
explanation - evolutionary biology - neo-darwinian mistake - view of epigenetic inheritance - Neo-darwinians believe that epigenetic inheritance is only short lived. - However, the Noble brothers contend that if the changes in the environment last for many generations, - the epigenetic change can exceed a threshold and become permanently assimilated into the genome - Such a threshold is plausible because without it, a permanent change encoded into the genome would be maladaptive if the environmental change reverted back to the previous state
what formed the basis all the way from the 1950s to now so over a period 00:25:25 of over 70 years has really to be undone it has to be revised fundamentally root and Branch there can't be compromises about it
for - quote - 70 years of evolutionary biology has to be undone
your 00:07:20 generation and the generation after it rejected purpose in nature but you guys said no
for - evolutionary biology - purpose in nature Denis Noble - Ray Noble
for - physiology rescues evolutionary biology - Denis Noble
from - youtube - IAI interview - Why Dawkins is Wrong - Denis Noble
for - paper - Physiology restores purpose to evolutionary biology - Denis Noble - Raymond Noble - year - 2023
from - youtube - IAI interview - Why Dawkins is wrong - Denis Noble - https://hyp.is/eqKOYhVVEe-XVKuwMtOTTg/docdrop.org/video/dCLRKP9NW8I/
the organism has that ability already the reason is simply 00:17:41 because it could use the chance events that occur in his molecular mechanisms there's where the creativity comes from then the question is what what emerges from that do you want to keep and what do you want to reject
for - key insight - eliminating cartesian dualism in biology - creativity - multi-scale explanation
key insight - eliminating cartesian dualism in biology - Noble advances a radical and simple explanation to explain how<br /> - higher level organisms and cellular mechanisms make the decisions that inform the genetic switches which decision path to make - The higher level system takes advantage of the random events in molecular mechanisms and chooses the ones that are most fit - This has the potential to explain creativity at all living scales, up to human consciousness itself!
four 00:08:25 major common misunderstandings that have infected our understanding of what it is to be a living system
for - molecular biology - paradigm shift - living system - 4 common misunderstandings - book - Understanding Living Systems - 4 common misunderstandings
4 common misunderstandings of living systems - 1. The central dogma of molecular biology - one way causation - Genes (DNA) to - proteins to - organism - 2. The Weismann Barrier - 3. DNA as self-replicator - 4. Separation of Replicator (DNA) and Vehicle (Living cell) are completely separate
biology Beyond The 00:00:19 genome
for - book - Biology Beyond the Genome - author - scientist - biologist - Denis Noble - book - Understanding Living Systems
for - Keith Baverstock - paper - The Gene and Appraisal
from - youtube - Biology Beyond the Gene - Denis Noble - https://hyp.is/UrvwdhVDEe-QWrPAx9y1aw/docdrop.org/video/bzXFSufDDn8/
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Such feelings are rooted in seeing life through the distorting filters of desire and fear
adjacency - between - existential isolation - desire and fear - adjacency statement -Desire of the other emerges from a sense of lack in the totality of reality - fear of the other emerges from a sense of avoidance of aspects of reality - Biologically , we have an innate desire and fear instinct - We desire to that which helps us survive - We fear that which threatens our survival - The psychological construction of the self takes cues from this biological attraction and aversion - the self-consciousness of the biological self as individual that is a separate entity from the environment - It is interesting to ponder how we could reconcile this difference
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for - adjacency - microscopic biology - macroscopic ecology - multi-scale competency architecture - Michael Levin - Jonas Wickman - micro-to-macro
paper details - title - Eco-evolutionary emergence of macroecological scaling in plankton communities - author - Jonas Wickman - Elena Litchman - date - feb 15, 2024 - publication - Science VOL. 383, NO. 6684
reference - https://www.science.org/doi/10.1126/science.adk6901
summary - This is a very interesting finding that links rules in the micro world to behavior in the macro. - It is relevant to Michael Levin's research on multi-scale competency architecture
question - how would this impact the micro relations between - the microscopic world of humans - the normal macroscopic world of humans
Dubbed “litigation terrorism” by Joseph Stiglitz, the Nobel prize-winning economist. ISDS is a corporate tribunal system
for - litigation terrorism - ISDS - corporate tribunal system - Michael Levin - multi-scale competency architecture - example - adjacency - evolutionary biology - corporate law - climate crisis
adjacency - between - corporate law - climate crisis - evolutionary biology - cultural evolution - adjacency statement - Biologist Michael Levin's multi-scale competency architecture of evolutionary biology seems to apply here - in the field of corporate law - Corporations can be viewed as one level of a social superorganism in a cultural evolution process - Governments can be viewed similiarly, but at a higher level - The ISDS is being weaponized by the same corporations destroying the global environment to combat the enactment of government laws that pose a threat to their livelihood - Hence, the ISDS has been reconfigured to protect the destroyers of the environment so that they can avoid dealing with their unacceptable externalizations - The individual existing at the lower level of the multi-scale competency architecture(the corporation) is battling to survive against the wishes of the higher level individual (the government) in the same multi-scale competency architecture
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for - multi scale competency architecture - Michael Levin - evolutionary biology - rapid whole system change - adjacency - multi scale competency architecture - rapid whole system change - stop reset go - Deep Humanity - Indyweb - Indranet - major evolutionary transition in individuality - MET - superorganism - cumulative cultural evolution of individuality
adjacency - between - multi scale competency architecture - rapid whole system change - progress trap - stop reset go - Deep Humanity - Indyweb - Indranet - major evolutionary transition in individuality - MET - superorganism - cumulative cultural evolution of individuality - adjacency statement - The idea of multi scale competency architecture can be extended to apply to the cultural level. - in the context of humanity's current existential poly /meta/ perma crisis, - rapid whole system change - (a cultural behavioural paradigm shift) - is required within a few short years - to avoid the worst impacts of - catastrophic, - anthropogenic - climate change, which is entangled with a host of other earth system boundary violations including - biodiversity loss - fresh water scarcity - - the driver of evolution through major evolutionary transitions in individuality has given rise to the level of cultural superorganisms that include all previous levels - progress and its intended consequences of progress traps play a major role in determining the future evolutionary trajectory of our and many other species - our species is faced with a few choice permutations in this regard: - individually regulate behaviour aligned with a future within earth system boundaries - collectively regulate behaviour aligned with a future within earth system boundaries - pursue sluggish green growth / carbon transition that is effectively tinkering at the margins of rapid whole system change - BAU - currently, there doesn't appear to be any feasible permutation of any of the above choices - There is insufficient worldview alignment to create the unity at scale for report whole system change - individual incumbent state and corporate actors still cling too tightly to the old, destructive regime, - creating friction that keeps the actual rate of change below the required - Stop Reset Go, couched within the Deep Humanity praxis and operationalized through the Indyweb / Indranet individual / collective open learning system provides a multi-dimensional tool for a deep educational paradigm shift that can accelerate both individual and collective upregulation of system change
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for - healthy eating - Dr. William Li - nutrition - healthy food - inflammation - angiogenesis
summary - A good interview about human health and healthy diet. William Li begins by talking about angiogenesis as a key aspect of human health - and how pathology of angiogenesis is at the root of many major diseases. - The interviewer then asks Dr. Li about the connection between another keystone disease, and angiogenesis. - Dr. Li then describes some healthy foods and good dietary practices including extra virgin olive oil.
adjacency - between - angiogenesis - inflammation - Micheal Levine's work - evolutionary biology - adjacency statement - they all seem related, as evolutionary biology has created legacy subsystems within the human body
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for - Michael Levin - Developmental biology - evolutionary biology
for - Micheal Levin - developmental biology - evolutionary biology - cellular intelligence
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for: evolutionary biology, big history, DH, Deep Humanity, theories of consciousness, ESP project, Earth Species Project, Michael Levin, animal communication, symbiocene
title: The Deep History of Ourselves: The Four-Billion-Year Story of How We Got Conscious Brains
doi: 0.1080/09515089.2022.2160311
ABSTRACT
comment
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05:00 fighting against biology (chronotypew)
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19:00 people teach personality at coaching, but it fails; what scales is biology, not personality
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for: sensory ecology, conservation biology, adjacency, adjacency - sensory ecology - conservation biology, anthropogenic sensory pollutants
title: Why conservation biology can benefit from sensory ecology
Another feature of this vision that aligns well with Buddhist ideas is the lack of a permanent, unique, unitary Self [68]. The picture given by the evolutionary cell-biological perspective is one where a cognitive agent is seen as a self-reinforcing process (the homeostatic loop), not a thing [69,70,71].
for: Michael Levine, developmental biology, human superorganism, multi-scale competency architecture, eukaryote multi-cellular superorganism - interlevel communication, interoception
definition: multi-scale competency architecture
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Capra Biosciences harnesses the superpowers of a biofilm-forming organism Marinobacter atlanticus to make fat-soluble products like retinol which is used in anti-aging face creams, and high-end industrial lubricants for electric car engines
Some startups, like MicroByre, have been working to domesticate those reluctant, recalcitrant, and rebellious microbes by adapting them for use in the lab and creating genetic tools to manipulate them
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Biology used to be considered taxonomy and dissection, like listing and looking at. But now biology, modern biology, is a molecular science.
What is modern biology... a vast and eclectic field composed of many specialized disciplines that study the structure, function, growth, distribution, evolution, or other features of living organisms.
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The notion of functional integration as a basis for biological identity was fully developed only in the 19th century, where it was transformed by the rise of both cell and evolutionary theory. Herbert Spencer
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Found this webpage for a 3D brain model when someone (maybe frymatic?) mentioned a region of the brain I was having trouble imagining.
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