- Nov 2023
-
www-nature-com.ezproxy.rice.edu www-nature-com.ezproxy.rice.edu
-
triggering homologous recombination and creating genetic instability10,11,12,13
-
- Apr 2021
-
blog.addgene.org blog.addgene.org
-
dsDNA substrate is best for insertions or deletions greater than approximately 20 nucleotides, while ssDNA substrate is best for point mutations or changes of only a few base pairs.
-
- Mar 2021
-
virological.org virological.org
-
Virological. ‘Recombinant SARS-CoV-2 Genomes Involving Lineage B.1.1.7 in the UK - SARS-CoV-2 Coronavirus / SARS-CoV-2 Molecular Evolution’, 17 March 2021. https://virological.org/t/recombinant-sars-cov-2-genomes-involving-lineage-b-1-1-7-in-the-uk/658.
-
- Feb 2021
-
twitter.com twitter.com
-
Eric Feigl-Ding. (2020, December 6). HUMAN➡️MINKS➡️HUMAN transmission on mink farms in NL. 68% of the tested farm workers and/or contacts had evidence of #SARSCoV2 infection. The coronavirus mutated & even evolved within minks before transmitted back to humans—& keeps #COVID19 perpetuating. Https://t.co/5ARZ6Pq5mO https://t.co/fhrQC9ZVDo [Tweet]. @DrEricDing. https://twitter.com/DrEricDing/status/1335419078446551041
-
- Jan 2021
-
www-pnas-org.ezproxy.rice.edu www-pnas-org.ezproxy.rice.edu
-
Aminimumof%20basepairsinacompletelyhomologoussegmentisrequiredforsignificantrecombination.Thereisanexponentialincreaseinthefre-quencyofrecombinationwhenthelengthofhomologousDNAisincreasedfrom20basepairsto74basepairsandanapparentlylinearincreasewithlongerDNAsegments.Mis-matcheswithinahomologoussegmentcandramaticallyde-creasethefrequencyofrecombination.
A minimum of 20 base pairs in a completely homologous segment is required for significant recombination. There is an exponential increase in the frequency of recombination when the length of homology increases from 20 to 74 bp and an apparently linear increase with longer DNA segments. Mismatches within a homologous segment can dramatically decrease the frequency of recombination.
-
- Jul 2020
-
www.cell.com www.cell.com
-
How scientists know COVID-19 is way deadlier than the flu. (2020, July 2). Science. https://www.nationalgeographic.com/science/2020/07/coronavirus-deadlier-than-many-believed-infection-fatality-rate-cvd/
-
- Mar 2020
-
www-nature-com.ezproxy.rice.edu www-nature-com.ezproxy.rice.edu
-
In E. coli, homologous recombination occurs most frequently when there is a contiguous stretch of sequence >25 bp
-