302 Matching Annotations
  1. Aug 2024
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    Multi-modal adaptor-clathrin contacts drive coated vesicleassembly
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    1. EMBOpress 20 Aug 2024

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    biorxiv.org/content/10.1101/2021.05.22.445240v1
  3. May 2024
  4. www.biorxiv.org www.biorxiv.org
    Control of mammalian brain aging by the unfolded protein response (UPR)
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    1. EMBOpress 22 May 2024

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    biorxiv.org/content/10.1101/2020.04.13.039172v1
  5. Apr 2024
  6. www.biorxiv.org www.biorxiv.org
    Condensate functionalization with motors directs their nucleation in space and allows manipulating RNA localization
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    1. EMBOpress 23 Apr 2024

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    biorxiv.org/content/10.1101/2022.07.10.499452v1
  7. Mar 2024
  8. www.biorxiv.org www.biorxiv.org
    Plant YTHDF proteins are direct effectors of antiviral immunity against an m6A-containing RNA virus
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    1. EMBOpress 20 Mar 2024

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      PeerReviewed EMBOPress The EMBO Journal plant biology
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    biorxiv.org/content/10.1101/2022.10.19.512835v1
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    Regulation of branched versus linear Arp2/3-generated actin filaments
    1
    1. EMBOpress 07 Mar 2024

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    biorxiv.org/content/10.1101/2022.05.06.490861v1
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    Extracellular vesicles and co-isolated endogenous retroviruses differently affect dendritic cells
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    1. EMBOpress 06 Mar 2024

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    biorxiv.org/content/10.1101/2023.01.27.525863v1
  11. Feb 2024
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    Cryo-EM structure of lipid embedded human ABCA7 at 3.6 &Aring resolution
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    1. EMBOpress 27 Feb 2024

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    biorxiv.org/content/10.1101/2021.03.01.433448v2
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    Pioneer activity distinguishes activating from non-activating pluripotency transcription factor binding sites
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    1. EMBOpress 07 Feb 2024

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    biorxiv.org/content/10.1101/2022.07.27.501606v1
  14. Jan 2024
  15. www.biorxiv.org www.biorxiv.org
    Human liver organoids model progressive inflammatory and fibrotic injury in non-alcoholic fatty liver disease
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    1. EMBOpress 17 Jan 2024

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    biorxiv.org/content/10.1101/2022.07.19.500693v2
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    Arp2/3 inhibition switches Eps8’s network associations to favour longer actin filament formation necessary for tunneling nanotubes
    1
    1. EMBOpress 06 Jan 2024

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    biorxiv.org/content/10.1101/2022.08.24.504515v2
  17. Dec 2023
  18. www.biorxiv.org www.biorxiv.org
    Monomeric α-Synuclein activates the Plasma Membrane Calcium Pump
    1
    1. EMBOpress 19 Dec 2023

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    biorxiv.org/content/10.1101/2022.02.21.481193v2
  19. www.biorxiv.org www.biorxiv.org
    Adaptive Pathfinding by Nucleokinesis during Amoeboid Migration
    1
    1. EMBOpress 15 Dec 2023

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    biorxiv.org/content/10.1101/2023.05.19.540965v1
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    The ribosome-associated chaperone Zuo1 controls translation upon TORC1 inhibition
    1
    1. EMBOpress 15 Dec 2023

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    biorxiv.org/content/10.1101/2022.12.09.519716v1
  21. www.biorxiv.org www.biorxiv.org
    The Response of the Eukaryotic Replisome to G-quadruplex- and i-motif-forming Sequences
    1
    1. EMBOpress 13 Dec 2023

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    biorxiv.org/content/10.1101/2022.11.18.517070v2
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    Thiol reductive stress activates the hypoxia response pathway
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    1. EMBOpress 13 Dec 2023

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    biorxiv.org/content/10.1101/2023.03.06.531274v2
  23. www.biorxiv.org www.biorxiv.org
    YAP antagonizes TEAD-mediated AR signaling and prostate cancer growth
    1
    1. EMBOpress 01 Dec 2023

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    biorxiv.org/content/10.1101/2022.08.01.502314v1
  24. Nov 2023
  25. www.biorxiv.org www.biorxiv.org
    A bifunctional kinase-phosphatase module integrates mitotic checkpoint and error-correction signalling to ensure mitotic fidelity
    1
    1. EMBOpress 30 Nov 2023

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    biorxiv.org/content/10.1101/2022.05.22.492960v2
  26. www.biorxiv.org www.biorxiv.org
    Vimentin intermediate filaments organize organellar architecture in response to ER stress
    1
    1. EMBOpress 28 Nov 2023

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    biorxiv.org/content/10.1101/2022.03.24.485587v1
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    A region-resolved proteomic map of the human brain enabled by high-throughput proteomics
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    1. EMBOpress 21 Nov 2023

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    biorxiv.org/content/10.1101/2023.06.05.543676v1
  28. www.biorxiv.org www.biorxiv.org
    Comprehensive comparison of female germ cell development in vitro and in vivo identifies epigenetic gene regulation crucial for oocyte development and embryonic competence
    1
    1. EMBOpress 17 Nov 2023

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    biorxiv.org/content/10.1101/2023.02.15.528760v1
  29. www.biorxiv.org www.biorxiv.org
    A network of small RNAs regulates sporulation initiation in C. difficile
    1
    1. EMBOpress 15 Nov 2023

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    biorxiv.org/content/10.1101/2022.10.17.512509v1
  30. Oct 2023
  31. www.biorxiv.org www.biorxiv.org
    EMBRYO-UTERINE INTERACTION COORDINATES MOUSE EMBRYOGENESIS DURING IMPLANTATION
    1
    1. EMBOpress 05 Oct 2023

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    biorxiv.org/content/10.1101/2022.06.13.495767v1
  32. Sep 2023
  33. www.biorxiv.org www.biorxiv.org
    Mechanisms and physiological function of daily haemoglobin oxidation rhythms in red blood cells
    1
    1. EMBOpress 06 Sep 2023

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    biorxiv.org/content/10.1101/2021.10.11.463714v2
  34. www.biorxiv.org www.biorxiv.org
    PTEN deficiency exposes a requirement for an ARF GTPase module in integrin-dependent invasion in ovarian cancer.
    1
    1. EMBOpress 06 Sep 2023

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    biorxiv.org/content/10.1101/2022.11.29.518198v1
  35. www.biorxiv.org www.biorxiv.org
    A Sterol-PI(4)P exchanger controls the Tel1/ATM axis of the DNA Damage Response
    1
    1. EMBOpress 02 Sep 2023

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    biorxiv.org/content/10.1101/2022.07.13.499867v1
  36. www.biorxiv.org www.biorxiv.org
    Phosphorylation controls spatial and temporal activities of motor-PRC1 complexes to complete mitosis
    1
    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2023.03.11.531660v1
  37. Aug 2023
  38. www.biorxiv.org www.biorxiv.org
    Randomly incorporated genomic 6mA delays zygotic transcription initiation
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    1. EMBOpress 25 Aug 2023

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    biorxiv.org/content/10.1101/2022.10.27.514014v1
  39. www.biorxiv.org www.biorxiv.org
    Senescent cell death as an aging resistance mechanism in naked mole-rat
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    1. EMBOpress 04 Aug 2023

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    biorxiv.org/content/10.1101/2020.07.02.155903v1
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    Synaptotagmin 1 mediates toxicity of botulinum neurotoxin type A
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    1. EMBOpress 04 Aug 2023

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    biorxiv.org/content/10.1101/2022.02.28.482398v1
  41. www.biorxiv.org www.biorxiv.org
    Direct observation of coordinated assembly of individual native centromeric nucleosomes
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    1. EMBOpress 03 Aug 2023

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    biorxiv.org/content/10.1101/2023.01.20.524981v2
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    Evolutionary transcriptomics reveals longevity mostly driven by polygenic and indirect selection in mammals
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    1. EMBOpress 02 Aug 2023

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    biorxiv.org/content/10.1101/2023.01.09.523139v1
  43. Jul 2023
  44. www.biorxiv.org www.biorxiv.org
    Characterization of the REC114-MEI4-IHO1 complex regulating meiotic DNA double-strand break formation
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    1. EMBOpress 29 Jul 2023

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    biorxiv.org/content/10.1101/2023.01.11.523614v1
  45. www.biorxiv.org www.biorxiv.org
    Ribonucleotide synthesis by NME6 fuels mitochondrial gene expression
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    1. EMBOpress 28 Jul 2023

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    biorxiv.org/content/10.1101/2022.11.29.518352v1
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    Cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phase
    1
    1. EMBOpress 15 Jul 2023

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    biorxiv.org/content/10.1101/2023.01.12.523718v1
  47. www.biorxiv.org www.biorxiv.org
    Centrosome amplification fine-tunes tubulin acetylation to differentially control intracellular organization
    1
    1. EMBOpress 13 Jul 2023

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    biorxiv.org/content/10.1101/2022.10.17.512471v1
  48. Jun 2023
  49. www.biorxiv.org www.biorxiv.org
    HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion
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    1. EMBOpress 29 Jun 2023

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    biorxiv.org/content/10.1101/2022.10.27.514062v1
  50. www.biorxiv.org www.biorxiv.org
    Structural basis of ubiquitin-independent PP1 complex disassembly by p97
    1
    1. EMBOpress 29 Jun 2023

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    biorxiv.org/content/10.1101/2022.06.24.497491v1
  51. www.biorxiv.org www.biorxiv.org
    Multivalent BARD1-nucleosome interactions facilitate H2A ubiquitylation by BRCA1/BARD1
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.08.09.503292v2
  52. www.biorxiv.org www.biorxiv.org
    PERK Signaling Promotes Mitochondrial Elongation By Remodeling Membrane Phosphatidic Acid
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.02.23.481593v2
  53. www.biorxiv.org www.biorxiv.org
    Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response
    1
    1. EMBOpress 28 Jun 2023

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    biorxiv.org/content/10.1101/2022.12.21.521356v1
  54. www.biorxiv.org www.biorxiv.org
    Pseudomonas aeruginosa mechanosensing controls cell polarity during twitching by activating two antagonistic response regulators
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    1. EMBOpress 24 Jun 2023

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    biorxiv.org/content/10.1101/2022.11.15.516588v1
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    Two distinct mechanisms underlie dosage sensitivity in Pumilio1-associated diseases
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    1. EMBOpress 16 Jun 2023

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    biorxiv.org/content/10.1101/2021.03.11.435015v5
  56. www.biorxiv.org www.biorxiv.org
    Stable kinetochore-microtubule attachment requires loop-dependent Ndc80-Ndc80 binding
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    1. EMBOpress 15 Jun 2023

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    biorxiv.org/content/10.1101/2022.08.25.505310v1
  57. www.biorxiv.org www.biorxiv.org
    Deterministic and probabilistic fate decisions co-exist in a single retinal lineage
    1
    1. EMBOpress 10 Jun 2023

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    biorxiv.org/content/10.1101/2022.08.11.503564v1
  58. www.biorxiv.org www.biorxiv.org
    Functionally distinct promoter classes initiate transcription via different mechanisms reflected in focused versus dispersed initiation patterns
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    1. EMBOpress 10 Jun 2023

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    biorxiv.org/content/10.1101/2022.09.30.509643v2
  59. May 2023
  60. www.biorxiv.org www.biorxiv.org
    Ubx5-Cdc48 assists the protease Wss1 at DNA-protein crosslink sites in yeast
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    1. EMBOpress 25 May 2023

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    biorxiv.org/content/10.1101/2022.05.30.493988v1
  61. www.biorxiv.org www.biorxiv.org
    eIF3 mRNA selectivity profiling reveals eIF3k as a cancer-relevant regulator of ribosome content
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    1. EMBOpress 25 May 2023

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    biorxiv.org/content/10.1101/2022.08.28.505560v2
  62. www.biorxiv.org www.biorxiv.org
    FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors
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    1. EMBOpress 24 May 2023

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    biorxiv.org/lookup/doi/10.1101/2022.10.12.511867
  63. www.biorxiv.org www.biorxiv.org
    ROR1 plays a critical role in pancreatic tumor-initiating cells with a partial EMT signature.
    1
    1. EMBOpress 19 May 2023

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    DASH/Dam1 complex mutants stabilize ploidy by weakening kinetochore-microtubule attachments
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  65. Apr 2023
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    TOR acts as metabolic gatekeeper for auxin-dependent lateral root initiation in Arabidopsis thaliana
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    An RNA-binding switch drives ribosome biogenesis and tumorigenesis downstream of RAS oncogene
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    Cell-extrinsic autophagy in mature adipocytes regulates anti-inflammatory response to intestinal tissue injury through lipid mobilization
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    Single cell analysis of lymphatic endothelial cell fate specification and differentiation during zebrafish development
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  70. Mar 2023
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    Hda1C limits divergent non-coding transcription and restricts transcription initiation frequency
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    Reconstitution of centrosome positioning by the production of pushing forces in microtubules growing against the actin network.
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    The Grainyhead/LSF transcription factor GRH-1 is rhythmically required for molting
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    Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and C53-mediated autophagy
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    An Arrayed Genome-Wide Perturbation Screen Identifies the Ribonucleoprotein hnRNP K As Rate-Limiting for Prion Propagation
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    Uncoupling from transcription protects polyadenylation site cleavage from inhibition by DNA damage
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    The cryo-EM structure of the CENP-A nucleosome in complex with ggKNL2
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    The eukaryotic translation initiation factor eIF4E reprogrammes the splicing machinery anddrives alternative splicing
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    Structure and mechanism of a novel cytomegaloviral DCAF mediating interferon antagonism
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    The Proxitome of Arabidopsis Processing Bodies Reveals a Condensate-Membrane Interface Instructing Actin-Driven Directional Growth
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    TORC1 phosphorylates and inhibits the ribosome preservation factor Stm1 to activate dormant ribosomes
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    MitoStores: Chaperone-controlled protein granules store mitochondrial precursors in the cytosol
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    Retromer oligomerization drives SNX-BAR coat assembly and membrane constriction
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    Structure of a bacterial ribonucleoprotein complex central to the control of cell envelope biogenesis
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    The blood vasculature instructs lymphatics patterning in a SOX7-dependent manner
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    TSC2 regulates tumor susceptibility to TRAIL-mediated T cell killing by orchestrating mTOR signaling
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    Transient ribosome slowdown at the decoding step triggers mRNA degradation independent of Znf598 in zebrafish
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    A molecular mechanism by which amyloid-β induces transcriptional inactivation of CREB in Alzheimer's Disease
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  91. Jan 2023
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    Plasma membrane topography governs the three-dimensional dynamic localization of IgM B cell receptor clusters
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    Condensin pinches a short negatively supercoiledDNA loop during each round of ATP usage
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    When Yeast Cells Change their Mind: Cell Cycle 'Start' is Reversible under Starvation
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    Structural and biochemical basis of FANCI-FANCD2 interdependent ubiquitination
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    Cue-specific remodeling of the neuronal transcriptome through intron retention programs
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    The E3 ligase RNF115 regulates phagosome maturation and host response to bacterial infection
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    A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
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    m6A is required for resolving progenitor identity during planarian stem cell differentiation
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    Structure and functional mapping of the KRAB-KAP1 repressor complex
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    Temporal and sequential transcriptional dynamics define lineage shifts in corticogenesis
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    An ERAD-independent role for rhomboid pseudoprotease Dfm1 in mediating sphingolipid homeostasis
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    RNA-mediated nucleosome depletion is required for elimination of transposon-derived DNA.
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    Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity
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    Cellular stress in brain organoids is limited to a distinct and bioinformatically removable subpopulation.
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    HEAT SHOCK FACTOR BINDING PROTEIN limits meiotic crossovers by repressing HEI10 transcription
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    TSG101 Associates with PARP1 and is Essential for PARylation and DNA Damage-induced NF-κB Activation
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    A conserved signaling pathway activates bacterial CBASS immune signaling in response to DNA damage
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    CRYPTOCHROME suppresses the circadian proteome and promotes protein homeostasis
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    Naked mole-rat hematopoietic stem and progenitors are highly quiescent with an inherent myeloid bias
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    Regulation of mitochondrial proteostasis by the proton gradient
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    Heterotypic Assembly Mechanism Regulates CHIP E3 Ligase Activity
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    Mitotic checkpoint gene expression is tuned by coding sequences
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    Nuclear Pore Complex Acetylation Regulates mRNA Export and Cell Cycle Commitment in Budding Yeast
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    Cellular toxicity of iHAP1 and DT-061 does not occur through PP2A-B56 targeting
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    Topoisomerase II poisons inhibit vertebrate DNA replication through distinct mechanisms
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    biorxiv.org/content/10.1101/2021.10.12.464107v2
  119. www.biorxiv.org www.biorxiv.org
    Cooperative Amyloid Fibre Binding and Disassembly by the Hsp70 disaggregase
    1
    1. EMBOpress 21 Nov 2022

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    biorxiv.org/content/10.1101/2021.08.29.458036v1
  120. www.biorxiv.org www.biorxiv.org
    Precise control of microtubule disassembly in living cells
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    1. EMBOpress 21 Nov 2022

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    biorxiv.org/content/10.1101/2021.10.08.463668v1
  121. www.biorxiv.org www.biorxiv.org
    Varicella-Zoster Virus ORF9 Is an Antagonist of the DNA Sensor cGAS
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    1. EMBOpress 21 Nov 2022

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    biorxiv.org/content/10.1101/2020.02.11.943415v2
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    Self-ubiquitination of a pathogen type-III effector traps and blocks the autophagy machinery to promote disease
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    1. EMBOpress 21 Nov 2022

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    biorxiv.org/content/10.1101/2021.03.17.435853v3
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    A temporally controlled sequence of X-chromosomeinactivation and reactivation defines female mouse in vitro germ cells with meiotic potential
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    biorxiv.org/content/10.1101/2021.08.11.455976v3
  124. Jun 2022
  125. www.biorxiv.org www.biorxiv.org
    A RIF1 and KAP1-based, double-bookmarking system generates a toggle switch that stabilises the identities of the active and inactive X chromosomes during random X inactivation in mouse
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    biorxiv.org/content/10.1101/2020.06.04.133512v2
  126. May 2022
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    Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly
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    biorxiv.org/content/10.1101/2021.10.26.465695v2
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    Structural basis for feedforward control in the PINK1/parkin pathway
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    biorxiv.org/content/10.1101/2021.08.16.456440v1
  129. www.biorxiv.org www.biorxiv.org
    UPF3A and UPF3B are redundant and modular activators of nonsense-mediated mRNA decay in human cells
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    biorxiv.org/content/10.1101/2021.07.07.451444v3
  130. www.biorxiv.org www.biorxiv.org
    CROP: A Retromer-PROPPIN complex mediating membrane fission in the endo-lysosomal system
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    biorxiv.org/content/10.1101/2021.09.06.459059v1
  131. Apr 2022
  132. www.biorxiv.org www.biorxiv.org
    A genetic program boosts mitochondrial function to power macrophage tissue invasion
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  133. www.biorxiv.org www.biorxiv.org
    Structure of the RZZ complex and molecular basis of Spindly-driven corona assembly at human kinetochores
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    A UPF1 variant drives conditional remodeling of nonsense-mediated mRNA decay
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    biorxiv.org/content/10.1101/2021.01.27.428318v2
  135. Mar 2022
  136. www.biorxiv.org www.biorxiv.org
    REDUCED ER-MITOCHONDRIA CONNECTIVITY PROMOTES NEUROBLASTOMA MULTIDRUG RESISTANCE
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    biorxiv.org/content/10.1101/2021.03.01.433120v1
  137. www.biorxiv.org www.biorxiv.org
    Autophagy suppression by TORC1 maintains epithelial plasma membrane integrity and inhibits syncytium formation
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    biorxiv.org/content/10.1101/2021.08.05.455228v1
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    Specialization of actin isoforms derived from the loss of key interactions with regulatory factors
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    biorxiv.org/content/10.1101/2021.02.09.430555v1
  139. www.biorxiv.org www.biorxiv.org
    Epigenetic Inheritance is Gated by Naive Pluripotency and Dppa2
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  140. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2020.08.18.255810
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  141. www.biorxiv.org www.biorxiv.org
    Rewiring phospholipid biosynthesis reveals robustness in membrane homeostasis and uncovers lipid regulatory players.
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    biorxiv.org/content/10.1101/2021.07.20.453065v1
  142. www.biorxiv.org www.biorxiv.org
    Heterotypic Aβ interactions facilitate amyloid assembly and modify amyloid structure
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    biorxiv.org/content/10.1101/2021.04.28.441786v1
  143. www.biorxiv.org www.biorxiv.org
    The nucleoporin Nup50 activates the Ran guanyl-nucleotide exchange factor RCC1 to promote mitotic NPC assembly
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    biorxiv.org/content/10.1101/2021.03.31.437874v1
  144. www.biorxiv.org www.biorxiv.org
    Balancing the length of distal tip is key for stability and signalling function of primary cilia
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  145. www.biorxiv.org www.biorxiv.org
    Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation
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    biorxiv.org/content/10.1101/2021.04.30.442163v1
  146. www.biorxiv.org www.biorxiv.org
    Versatile genetic toolbox for Prevotella copri enables studying polysaccharide utilization systems
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    biorxiv.org/content/10.1101/2021.03.19.436125v1
  147. Feb 2022
  148. www.biorxiv.org www.biorxiv.org
    Low membrane fluidity triggers lipid phase separation and protein segregation in vivo
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    biorxiv.org/content/10.1101/852160v2
  149. www.biorxiv.org www.biorxiv.org
    CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal
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    Molecular species selectivity of lipid transport creates a mitochondrial sink for di-unsaturated phospholipids
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    biorxiv.org/content/10.1101/2020.06.08.140129v1
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    Ontogeny and function of the circadian clock in intestinal organoids
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    biorxiv.org/content/10.1101/2020.04.22.053223v1
  152. Jan 2022
  153. www.biorxiv.org www.biorxiv.org
    Nascent polypeptide within the exit tunnel ensures continuous translation elongation by stabilizing the translating ribosome
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    biorxiv.org/content/10.1101/2021.02.02.429294v3
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    Genetic Control of Pluripotency Epigenome Determines Differentiation Bias in Mouse Embryonic Stem Cells
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    Helical Ordering of Envelope Associated Proteins and Glycoproteins in Respiratory Syncytial Virus Filamentous Virions
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    biorxiv.org/content/10.1101/2021.08.04.455049v2
  156. Dec 2021
  157. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2021.06.11.448011
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    The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation
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    biorxiv.org/content/10.1101/2020.12.09.417709v3
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    Bacteria elicit a phage tolerance response subsequent to infection of their neighbors
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    biorxiv.org/content/10.1101/2021.02.16.428622v1
  160. Nov 2021
  161. www.biorxiv.org www.biorxiv.org
    Acyl chain shortening induced by inhibition of acetyl-CoA carboxylase renders phosphatidylcholine redundant
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    Modulation of root growth by nutrient-defined fine-tuning of polar auxin transport
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    biorxiv.org/lookup/doi/10.1101/2020.06.19.160994
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    MARCO+ lymphatic endothelial cells sequester arboviruses to limit viremia and viral dissemination
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  164. Oct 2021
  165. www.biorxiv.org www.biorxiv.org
    Control of endoplasmic reticulum membrane biogenesis by regulators of lipid metabolism
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    RASSF1C oncogene elicits amoeboid invasion, cancer stemness and invasive EVs via a novel SRC/Rho axis
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    Role of endopeptidases in peptidoglycan synthesis mediated by alternative cross-linking enzymes in Escherichia coli
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    biorxiv.org/content/10.1101/2021.02.12.430937v2
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    Passive receptor dissociation driven by porin threading establishes active colicin transport through Escherichia coli OmpF
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    biorxiv.org/content/10.1101/2021.04.15.439832v1
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    The Torsin/ NEP1R1-CTDNEP1/ Lipin axis regulates nuclear envelope lipid metabolism for nuclear pore complex insertion
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    biorxiv.org/content/10.1101/2020.07.05.188599v1
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    Rotavirus Replication Factories Are Complex Ribonucleoprotein Condensates
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    biorxiv.org/content/10.1101/2020.12.18.423429v1
  171. Sep 2021
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    Novel proteostasis reporter mouse reveals different effects of cytoplasmic and nuclear aggregates on protein quality control in neurons
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    biorxiv.org/content/10.1101/2020.11.09.374231v1
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    Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
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    biorxiv.org/content/10.1101/2020.12.04.411561v1
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    https://biorxiv.org/cgi/content/10.1101/2021.04.01.438087
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    Msps Governs Acentrosomal Microtubule Assembly and Reactivation of Quiescent Neural Stem Cells
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    biorxiv.org/content/10.1101/2020.01.24.918227v1
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    Reciprocal Priming between RTKs within Recycling Endosomes Orchestrates Cellular Signaling Outputs
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    biorxiv.org/content/10.1101/2021.01.04.425243v2
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    A novel IKK- and proteasome-independent mechanism of RelA activation triggers senescence associated secretome via transcriptional repression of NFKBIA
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    De novo DNA methylation controls neuronal maturation during adult hippocampal neurogenesis
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    biorxiv.org/content/10.1101/2020.09.22.308692v1
  179. Aug 2021
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    Tudor staphylococcal nuclease acts as a docking platform for stress granule components in Arabidopsis thaliana
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    Mechanisms preventing Break-Induced Replication during repair of two-ended DNA double-strand breaks
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    Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection
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  184. Jul 2021
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    Nse5/6 inhibits the Smc5/6 ATPase to facilitate DNA substrate selection.
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    Increased levels of the mitochondrial import factor Mia40 prevent the aggregation of polyQ proteins in the cytosol
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    Amphipathic Bax core dimer forms part of apoptotic pore wall in the mitochondrial membrane
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    http://biorxiv.org/cgi/content/short/2020.12.23.424169
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    A cryo-EM structure of metazoan TRAPPIII, the multisubunit complex that activates the GTPase Rab1
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  190. Jun 2021
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    CyclinD1 controls development of cerebellar granule cell progenitors through phosphorylation and stabilization of ATOH1
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    CDC50A dependent phosphatidylserine exposure induces inhibitory post-synapse elimination by microglia
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    Integrated requirement of non-specific and sequence-specific DNA binding in MYC-driven transcription
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    biorxiv.org/content/10.1101/2020.05.04.076190v2
  194. May 2021
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    Somatic transposition in the Drosophila intestine occurs in active chromatin and is associated with tumor suppressor gene inactivation
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    REPRESSION BY HDAC3 AND DAX1 MEDIATES LINEAGE RESTRICTION OF EMBRYONIC STEM CELLS
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    Combinatorial action of transcription factors in open chromatin contributes to early cellular heterogeneity and organizer mesendoderm specification.
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  198. Apr 2021
  199. www.biorxiv.org www.biorxiv.org
    Transneuronal interactions facilitate axonal compartment formation
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    Cryo-EM reveals the complex architecture of dynactin's shoulder and pointed end
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    biorxiv.org/content/10.1101/2020.07.16.206359v1
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    Phosphoproteomics Reveals a Distinct Mode of Mec1/ATR Signaling in Response to DNA End Hyper-Resection
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    biorxiv.org/content/10.1101/2020.04.17.028118v1
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    Kinetochore individualization in meiosis I is required for centromeric cohesin removal in meiosis II
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    biorxiv.org/content/10.1101/2020.07.24.219873v1
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    The multi-scale architecture of mammalian sperm flagella and implications for ciliary motility
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    biorxiv.org/content/10.1101/2020.11.18.388975v1
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    Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit in trypanosomes
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    biorxiv.org/content/10.1101/2020.06.28.176446v4
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    Bacterial protein domains with a novel Ig-like fold bind human CEACAM receptors
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    biorxiv.org/content/10.1101/2020.06.09.141622v4
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    PLZF is a new substrate of CRBN with thalidomide and 5-hydroxythalidomide
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    biorxiv.org/content/10.1101/2020.02.28.969071v1
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    The structure of bacterial toxin CNFY reveals requirements for secretion, host cell recognition and endosomal release
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    biorxiv.org/content/10.1101/2020.04.07.029181v2
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    Self-assembly of multi-component mitochondrial nucleoids via phase separation
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  209. Feb 2021
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    CRYPTOCHROMES confer robustness, not rhythmicity, to circadian timekeeping
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    biorxiv.org/content/10.1101/2020.05.14.095968v1
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    Selective cross-linking of coinciding protein assemblies by in-gel cross-linking mass-spectrometry
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    biorxiv.org/content/10.1101/2020.07.10.193003v1
  212. biorxiv.org biorxiv.org
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    Zonal human hepatocytes are differentially permissive to Plasmodium falciparum malaria parasites
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    biorxiv.org/content/10.1101/2020.06.29.175968v1
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    Nucleo-plastidic PAP8/pTAC6 couples chloroplast formation with photomorphogenesis
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    biorxiv.org/content/10.1101/2020.03.10.985002v1
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    Tyrosine phosphorylation regulates hnRNPA2 granule protein partitioning & reduces neurodegeneration
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    biorxiv.org/content/10.1101/2020.03.15.992768v2
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    Modulation of Yorkie activity by alternative splicing is required for developmental stability
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    biorxiv.org/content/10.1101/2019.12.19.882779v1
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    Structural inventory of native ribosomal ABCE1-43S pre-initiation complexes
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    biorxiv.org/content/10.1101/2020.07.09.194902v1
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    Translation is required for miRNA-dependent decay of endogenous transcripts.
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    biorxiv.org/content/10.1101/2020.01.21.913483v1
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    Translational adaptation to heat stress is mediated by 5-methylcytosine RNA modification in Caenorhabditis elegans
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    biorxiv.org/content/10.1101/2020.03.21.001735v1
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    Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages
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    biorxiv.org/content/10.1101/2020.04.12.038067v2
  221. doi.org doi.org
    https://doi.org/10.1101/2020.06.18.160614
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    The tRNA pseudouridine synthase TruB1 regulates the maturation and function of let-7 miRNA
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    biorxiv.org/content/10.1101/2020.02.16.951954v2
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    Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins
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    biorxiv.org/content/10.1101/2020.06.16.155259v1
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    Human POT1 Prevents Severe Telomere Instability Induced by Homology Directed DNA Repair
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    biorxiv.org/content/10.1101/2020.01.20.912642v1
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    Cold induced chromatin compaction and nuclear retention of clock mRNAs resets the circadian rhythm
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    biorxiv.org/content/10.1101/2020.06.05.127290v1
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    The architecture of the centriole cartwheel-containing region revealed by cryo-electron tomography
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    biorxiv.org/content/10.1101/2020.07.21.068882v1
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    Cryo-EM Structure of Native Human Uromodulin, a Zona Pellucida Module Polymer
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    biorxiv.org/content/10.1101/2020.05.28.119206v1
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    TIP5 safeguards genome architecture of ground-state pluripotent stem cells
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    biorxiv.org/content/10.1101/2019.12.20.882282v1
  229. biorxiv.org biorxiv.org
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  230. Oct 2020
  231. doi.org doi.org
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    Fxr1 regulates sleep and synaptic homeostasis
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    Novel features of centriole polarity and cartwheel stacking revealed by cryo-tomography
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      PeerReviewed EMBOPress The EMBO Journal cell biology
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    biorxiv.org/content/10.1101/2020.07.17.208082v1
  234. www.biorxiv.org www.biorxiv.org
    Reprogrammed mRNA translation drives metabolic response to therapeutic targeting of ribosome biogenesis
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      PeerReviewed EMBOPress The EMBO Journal cancer biology
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    biorxiv.org/content/10.1101/847723v3
  235. www.biorxiv.org www.biorxiv.org
    The innate immune DNA sensor cGAS is a negative regulator of DNA repair hence promotes genome instability and cell death
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      PeerReviewed EMBOPress The EMBO Journal cell biology
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    biorxiv.org/content/10.1101/465401v1
  236. www.biorxiv.org www.biorxiv.org
    Stage-specific transcriptomes and DNA methylomes indicate an early and transient loss of transposon control in Arabidopsis shoot stem cells
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      PeerReviewed EMBOPress The EMBO Journal developmental biology
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    biorxiv.org/content/10.1101/430447v2
  237. www.biorxiv.org www.biorxiv.org
    Disrupting HIV-1 capsid formation causes cGAS sensing of viral DNA
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      PeerReviewed EMBOPress The EMBO Journal microbiology
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    biorxiv.org/content/10.1101/838011v1