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  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    Matrix-driven jamming dynamics mediates transition of ovarian cancer spheroids to stable morphologies
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    1. EMBOpress 20 May 2025

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    biorxiv.org/content/10.1101/2022.02.09.479678v3
  3. www.biorxiv.org www.biorxiv.org
    Mechanical forces and ligand-binding modulate Pseudomonas aeruginosa PilY1 mechanosensitive protein
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    1. EMBOpress 20 May 2025

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    biorxiv.org/content/10.1101/2023.08.03.551776v3
  4. Nov 2024
  5. www.biorxiv.org www.biorxiv.org
    Structural and biochemical analysis of ligand binding in yeast Niemann-Pick type C1-related protein
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    1. EMBOpress 27 Nov 2024

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    biorxiv.org/content/10.1101/2024.06.10.598172v2
  6. Jul 2024
  7. www.biorxiv.org www.biorxiv.org
    Structure of the human systemic RNAi defective transmembrane protein 1 (hSIDT1) reveals the conformational flexibility of its lipid binding domain
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    1. EMBOpress 24 Jul 2024

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    biorxiv.org/content/10.1101/2023.12.21.572875v2
  8. Feb 2024
  9. www.biorxiv.org www.biorxiv.org
    Cryo-EM structure of lipid embedded human ABCA7 at 3.6 &Aring resolution
    1
    1. EMBOpress 27 Feb 2024

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    biorxiv.org/content/10.1101/2021.03.01.433448v2
  10. www.biorxiv.org www.biorxiv.org
    Canalisation and plasticity on the developmental manifold of Caenorhabditis elegans
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    1. EMBOpress 24 Feb 2024

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    biorxiv.org/content/10.1101/2023.04.14.536891v2
  11. Sep 2023
  12. www.biorxiv.org www.biorxiv.org
    Estimation of crossbridge-state during cardiomyocyte beating using second harmonic generation
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    1. EMBOpress 01 Sep 2023

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    biorxiv.org/content/10.1101/2022.10.13.512034v1
  13. Aug 2023
  14. www.biorxiv.org www.biorxiv.org
    Direct observation of coordinated assembly of individual native centromeric nucleosomes
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    1. EMBOpress 03 Aug 2023

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    biorxiv.org/content/10.1101/2023.01.20.524981v2
  15. Apr 2023
  16. www.biorxiv.org www.biorxiv.org
    Preference of CAMSAP3 for microtubules with expanded lattice contributes to stabilization of the minus end
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    1. EMBOpress 11 Apr 2023

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    biorxiv.org/content/10.1101/2022.08.21.504720v2
  17. Mar 2023
  18. www.biorxiv.org www.biorxiv.org
    The human MRS2 magnesium binding domain is a regulatory feedback switch for channel activity.
    1
    1. EMBOpress 15 Mar 2023

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    biorxiv.org/content/10.1101/2022.09.27.509701v1
  19. Feb 2023
  20. www.biorxiv.org www.biorxiv.org
    Cryo-EM structure of the octameric pore of Clostridium perfringens β-toxin
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    1. EMBOpress 17 Feb 2023

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    biorxiv.org/content/10.1101/2021.11.23.469684v2
  21. Nov 2022
  22. www.biorxiv.org www.biorxiv.org
    Actin binding domain of Rng2 strongly inhibits actin movement on myosin II HMM through structural changes of actin filaments
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    1. EMBOpress 23 Nov 2022

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    biorxiv.org/content/10.1101/2020.04.14.041046v4
  23. www.biorxiv.org www.biorxiv.org
    Mechanistic insights into the enhancement or inhibition of phase separation by polyubiquitin chains of different lengths or linkages
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    1. EMBOpress 21 Nov 2022

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    biorxiv.org/content/10.1101/2021.11.12.467822v2
  24. www.biorxiv.org www.biorxiv.org
    Structural mechanism underpinning Thermus oshimai Pif1-mediated G-quadruplex unfolding
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    1. EMBOpress 21 Nov 2022

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    biorxiv.org/content/10.1101/2021.08.24.457465v1
  25. Oct 2021
  26. www.biorxiv.org www.biorxiv.org
    Rotavirus Replication Factories Are Complex Ribonucleoprotein Condensates
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    1. EMBOpress 05 Oct 2021

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    biorxiv.org/content/10.1101/2020.12.18.423429v1
  27. Aug 2021
  28. mp.weixin.qq.com mp.weixin.qq.com
    【分子优化】靶向无序蛋白的的先导化合物优化以及小分子调控无序蛋白的可能机制——诱导形成可溶寡聚物
    1
    1. zhentg 24 Aug 2021
      SV-AUC

      Sedimentation Velocity Analytical Ultracentrifugation

      biophysics
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    mp.weixin.qq.com/s
  29. Jul 2021
  30. www.biorxiv.org www.biorxiv.org
    Amphipathic Bax core dimer forms part of apoptotic pore wall in the mitochondrial membrane
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    biorxiv.org/content/10.1101/2020.12.18.423546v1
  31. May 2021
  32. cmi.hms.harvard.edu cmi.hms.harvard.edu
    cmi_itc200_getting_started_guide.pdf
    1
    1. zhentg 26 May 2021
      The two binding partners must be in identical buffersto minimize heats of dilution

      must be in identical buffer to minimize dilution heat

      ITC biophysics debug
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    cmi.hms.harvard.edu/files/cmi/files/cmi_itc200_getting_started_guide.pdf
  33. www.biorxiv.org www.biorxiv.org
    Spurious regulatory connections dictate the expression-fitness landscape of translation factors
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    1. EMBOpress 19 May 2021

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    biorxiv.org/content/10.1101/2020.11.27.400200v1
  34. Apr 2021
  35. www.biorxiv.org www.biorxiv.org
    https://doi.org/10.1101/2020.06.12.149229
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    biorxiv.org/content/10.1101/2020.06.12.149229v3
  36. www.biorxiv.org www.biorxiv.org
    Malaria parasites differentially sense environmental elasticity during transmission
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    biorxiv.org/content/10.1101/2020.09.29.319020v1
  37. www.biorxiv.org www.biorxiv.org
    The genotype-phenotype landscape of an allosteric protein
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    biorxiv.org/content/10.1101/2020.09.30.320812v1
  38. Mar 2021
  39. en.wikipedia.org en.wikipedia.org
    Microscale thermophoresis - Wikipedia
    1
    1. zhentg 31 Mar 2021
      The thermophoresis of a fluorescently labeled molecule A

      fluorescent label is needed? here the molecule A is protein or ligand?

      biophysics MST
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    en.wikipedia.org/wiki/Microscale_thermophoresis
  40. Feb 2021
  41. www.biorxiv.org www.biorxiv.org
    Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F
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    biorxiv.org/content/10.1101/2020.06.02.130047v1
  42. www.biorxiv.org www.biorxiv.org
    Cryo-EM Structure of Native Human Uromodulin, a Zona Pellucida Module Polymer
    1
    1. EMBOpress 25 Feb 2021

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    biorxiv.org/content/10.1101/2020.05.28.119206v1
  43. www.biorxiv.org www.biorxiv.org
    Pseudo-repeats in doublecortin make distinct mechanistic contributions to microtubule regulation
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    1. EMBOpress 25 Feb 2021

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    biorxiv.org/content/10.1101/808899v1
  44. Nov 2020
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural dynamics of potassium channel gating revealed by single molecule FRET
    1
    1. zhentg 30 Nov 2020

      by attaching acceptor and donor to different domains of a target protein, the interdomain dynamics can be monitored

      Single-molecule FRET biophysics protein dynamics
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    ncbi.nlm.nih.gov/pmc/articles/PMC4833211/
  46. Nov 2019
  47. www.biorxiv.org www.biorxiv.org
    Resolving kinesin stepping: one head at a time
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    1. EMBOpress 26 Nov 2019

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    biorxiv.org/content/10.1101/651281v1
  48. www.biorxiv.org www.biorxiv.org
    The Israeli Acute Paralysis Virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
    1
    1. EMBOpress 26 Nov 2019

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    biorxiv.org/content/10.1101/606236v1
  49. Sep 2019
  50. www.biorxiv.org www.biorxiv.org
    CRISPR Cas9 searches for a protospacer adjacent motif by one-dimensional diffusion
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    biorxiv.org/content/10.1101/264879v1
  51. www.biorxiv.org www.biorxiv.org
    Real-time observation of flexible domain movements in Cas9
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    1. EMBOpress 22 Sep 2019

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    biorxiv.org/content/10.1101/122069v2
  52. www.biorxiv.org www.biorxiv.org
    Real-time detection of condensin-driven DNA compaction reveals a multistep binding mechanism
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    biorxiv.org/content/10.1101/149138v1
  53. www.biorxiv.org www.biorxiv.org
    Tyrosination of α-Tubulin Controls The Initiation of Processive Dynein-Dynactin Motility
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    biorxiv.org/content/10.1101/027631v1
  54. Mar 2019
  55. nautil.us nautil.us
    The Man Who Tried to Redeem the World with Logic - Issue 21: Information - Nautilus
    1
    1. chrisaldrich 04 Mar 2019
      McCulloch and Pitts wrote up their findings in a now-seminal paper, “A Logical Calculus of Ideas Immanent in Nervous Activity,” published in the Bulletin of Mathematical Biophysics.

      reference at: https://link.springer.com/article/10.1007%2FBF02478259

      Walter Pitts Warren McCulloch biophysics neurobiology
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    nautil.us/issue/21/information/the-man-who-tried-to-redeem-the-world-with-logic