The black American Shakespearean actor, Ira Aldridge, plays Othello in St. Petersburg.
This is fascinating. In 1859, how many black actors were in the US? Where did they live?
20 Matching Annotations
- Dec 2024
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usrussiarelations.org usrussiarelations.org
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- Nov 2024
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hellopoetry.com hellopoetry.com
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(37˚)
I wonder if there will every come a time when I will see the number 37 in a context such as this and not think: Yiching change number 37, the clan? I have mixed feelings about whether I would feel good or bad if that day happened. I feel it might never happen? I mean, I might see thirty seven as an amount somewhere, but poetry and divination? Are these two sisters that should ever be separated?
I like to think of someone feeling warm. Perfectly warm. With their family and with themsleves.
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- Jul 2024
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Writebook<br /> Instantly publish your own books on the web for free, no publisher required.
ᔥ[[Evan Hildreth]] in Downloaded 37Signals’ Writebook at 2024-07-04 (accessed:: 2024-07-04 08:29 AM)
Downloaded 37Signals’ Writebook because free. I might try to run it locally as a Scrivener replacement, but I’m bristling at the thought of running a full Rails app on the server for what should be static files.
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- Oct 2023
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en.wikipedia.org en.wikipedia.org
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https://en.wikipedia.org/wiki/Shmita
During shmita, the land is left to lie fallow and all agricultural activity, including plowing, planting, pruning and harvesting, is forbidden by halakha (Jewish law).
The sabbath year (shmita; Hebrew: שמיטה, literally "release"), also called the sabbatical year or shǝvi'it (שביעית, literally "seventh"), or "Sabbath of The Land", is the seventh year of the seven-year agricultural cycle mandated by the Torah in the Land of Israel and is observed in Judaism.
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- 2 Kings 19:29
- Jewish law
- Isaiah 37:30
- Leviticus 25
- remission year
- Deuteronomy 15:1-6
- sabbaticals
- 2 Chronicles 36:20-21
- Exodus 23:10-11
- debt
- Deuteronomy 31:10-13
- Leviticus 25:5
- jubilee
- halakha
- Jeremiah 34:13-14
- Friends of the Link 2023-10-18
- time in relation to work
- Nehemiah 10:31
- agriculture
- shmita
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- Mar 2021
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Results for individual PALB2 variants were normalized relative to WT-PALB2 and the p.Tyr551ter (p.Y551X) truncating variant on a 1:5 scale with the fold change in GFP-positive cells for WT set at 5.0 and fold change GFP-positive cells for p.Y551X set at 1.0. The p.L24S (c.71T>C), p.L35P (c.104T>C), p.I944N (c.2831T>A), and p.L1070P (c.3209T>C) variants and all protein-truncating frame-shift and deletion variants tested were deficient in HDR activity, with normalized fold change <2.0 (approximately 40% activity) (Fig. 1a).
AssayResult: 4.9
AssayResultAssertion: Normal
StandardErrorMean: 0.44
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A total of 84 PALB2 patient-derived missense variants reported in ClinVar, COSMIC, and the PALB2 LOVD database were selected
HGVS: NM_024675.3:c.2794G>A p.(Val932Met)
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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SUPPLEMENTARY DATA
AssayResult: 77
AssayResultAssertion: Indeterminate
PValue: < 0.01
Approximation: Exact assay result value not reported; value estimated from Figure 6C.
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SUPPLEMENTARY DATA
AssayResult: -20
AssayResultAssertion: Indeterminate
PValue: < 0.05
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SUPPLEMENTARY DATA
AssayResult: 103.3
AssayResultAssertion: Not reported
PValue: > 0.9999
Comment: Exact values reported in Table S3.
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To this end, 44 missense variants found in breast cancer patients were identified in the ClinVar database (https://www.ncbi.nlm.nih.gov/clinvar) and/or selected by literature curation based on their frequency of description or amino acid substitution position in the protein (Supplemental Table S1).
HGVS: NM_024675.3:c.505C>A p.(Leu169Ile)
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www.nature.com www.nature.com
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While 3 VUS (p.W912G, p.L961P, and p.G1043D) had a dramatic impact on the percentage of cells showing RAD51 foci, 2 VUS (p.G937R and p.L947S) displayed a more minor effect.
AssayResult: 15.80 foci/cell
AssayResultAssertion: Indeterminate (described as "minor effect")
Range: 0 - 74
Comment: Exact values reported in "Source Data" file
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Source Data
AssayResult: 15.23
AssayResultAssertion: Abnormal
ReplicateCount: 2
StandardErrorMean: 6.42
Comment: Exact values reported in “Source Data” file. Discrepancy in “Source Data” file: protein reported as Q899X.
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Source Data
AssayResult: 7.08
AssayResultAssertion: Abnormal
ReplicateCount: 2
StandardDeviation: 0.54
StandardErrorMean: 0.38
Comment: Exact values reported in “Source Data” file.
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We, therefore, analyzed the effect of 48 PALB2 VUS (Fig. 2a, blue) and one synthetic missense variant (p.A1025R) (Fig. 2a, purple)29 on PALB2 function in HR.
HGVS: NM_024675.3:c.2962C>T p.(Q988X)
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www.cell.com www.cell.com
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Most Suspected Brugada Syndrome Variants Had (Partial) Loss of Function
AssayResult: 0.7
AssayResultAssertion: Abnormal
ReplicateCount: 17
StandardErrorMean: 0.6
Comment: This variant had loss of function of peak current (<10% of wildtype), therefore it was considered abnormal (in vitro features consistent with Brugada Syndrome Type 1). (Personal communication: A. Glazer)
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we selected 73 previously unstudied variants: 63 suspected Brugada syndrome variants and 10 suspected benign variants
HGVS: NM_198056.2:c.361C>T p.(Arg121Trp)
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- Feb 2021
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jmg.bmj.com jmg.bmj.com
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We analysed a total of 82 blood samples derived from 77 individuals (online supplemental table 3). These 77 individuals corresponded either to new index cases suspected to harbour a pathogenic TP53 variant or to relatives of index cases harbouring TP53 variants.
HGVS: NM_000546.5:c.736A>G p.(Met246Val)
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Supplemental material
AssayResult: 97
AssayResultAssertion: Normal
Comment: See Table S2 for details
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Supplemental material
AssayResult: 3.1
AssayResultAssertion: Abnormal
Comment: See Table S2 for details
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- Jun 2020
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www.defenseurdesdroits.fr www.defenseurdesdroits.fr
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Son article 37 précise que les États sont tenus de veiller à ce que « nul enfant ne soit soumis à la torture, ni à des peines ou des traitements cruels, inhumains ou dégradants »
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