17 Matching Annotations
  1. Nov 2023
    1. Inhibition of Glucose uptake in cancer cells. Malignant cells are known to have an enormous glucose uptake. That’s why I tell everybody that has cancer to immediately (a) get on a ketogenic diet, and (b) take High Dose Vitamin C. Note: Cancer cells consume glucose 200 times faster than ordinary cells. If you study cancer you know of the Warburg Effect. This is the aerobic glycolysis effect and it can be seen on PET scans. It’s pretty obvious. Fenbendazole limits cancer cell fueling with sugar by limiting this glucose uptake, decreasing the amount of what are called “glute transporters” (canals that take the glucose into cancer cells from the blood). An enzyme called hexokinase 2 is inhibited as well. This is very important. It helps those tumors to not divide rapidly and prevent sugar from getting in there.

      Sugar (glucose) is the primary fuel for cancer. Fenbendazole limits glucose uptake in cancer cells, limiting growth.

      Also a reason for adopting a ketogenic diet with high dose vitamin c.

  2. May 2023
    1. when the animal is prevented from making insulin the ability to develop atherosclerosis appears to cease, or is significantly lessened 14. On the flip side, once exogenous insulin is introduced into the pseudo-diabetic animals, they appear to develop atherosclerosis “normally” 15, and in the case of the dog study, it appears to only develop atherosclerosis in the arteries in which they were injected with insulin.16

      Example of direct link between insulin and atherosclerosis

  3. Nov 2022
  4. Aug 2022
    1. Metabolic risk factors

      Should we include these studies or just the ones in the heart section

    2. Heart disease

      Need to use all these studies

    1. However, there was one exception, the same as in many earlier studies. LDL cholesterol went up a little bit on average.


    2. 22 of 26 markers of cardiovascular disease risk improved in their patients, many quite significantly.


  5. Feb 2022
    1. Deepti Gurdasani. (2022, January 10). Lots of people dismissing links between COVID-19 and all-cause diabetes. An association that’s been shown in multiple studies- whether this increase is due to more diabetes or SARS2 precipitating diabetic keto-acidosis allowing these to be diagnosed is not known. A brief look👇 [Tweet]. @dgurdasani1. https://twitter.com/dgurdasani1/status/1480546865812840450

  6. Sep 2020
  7. Dec 2018
    1. The Heads Up Health web app is designed specifically to help you track ketones alongside all of your other vital health data.
    2. urine strips test for unused acetoacetate rather than the main ketone that our body does use, B-hydroxybutyrate.
    3. Why Measuring Ketones MattersBeing able to frequently and accurately measure the level of ketosis can be important for those following the ketogenic diet for clinical purposes as well as for overall health and performance. Due to individual variability in response to different types of food, having frequent feedback will aid individuals towards improving their understanding of how their body responds while increasing motivation and adherence.
    4. Zhou, W., Mukherjee, P., Kiebish, M. A., Markis, W. T., Mantis, J. G., & Seyfried, T. N. (2007). The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer. Nutrition & metabolism, 4(1), 5.
    5. More specific for those following a ketogenic diet, to date, six studies have compared breath acetone levels with blood b-hydroxybutyrate levels and have found a strong correlation (R2= 0.77) (8). One study in particular directly compared blood, breath, and urine samples of 12 healthy individuals undergoing an experimental protocol designed to induce a state of ketosis. The results demonstrated that plasma acetoacetate was best predicted by breath acetone (6). Therefore, it appears that breath acetone assessments are a fast and accurate way to test for the degree of ketosis.
    6. When following a ketogenic diet, acetyl-CoA is produced in the liver from the breakdown of fat and is used to produce acetoacetate, one of three ketone bodies.  From there, acetoacetate can be converted to the other two “ketone bodies”, b-hydroxybutyrate and acetone.  While b-hydroxybutyrate is tested via blood meters, acetone actually diffuses into the lungs and can be measured by testing exhaled breath (7)! Acetone is a byproduct of fat metabolism and is present in the breath of all humans but in different concentrations.
    1. To reduce the urinary loss of these important metabolicfuels, which furnish a significant amount of the caloric re-quirements during fasting, the kidney is capable of reab-sorbing a portion of the increased filtered load of ketoacids.A linear correlation has been found between the urinaryexcretion of acetoacetate and the plasma concentration, oncethe renal threshold has been exceeded.

      This seems to indicate that when the body no longer needs ketones it will excrete the excess via the urine.