- Feb 2023
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www.youtube.com www.youtube.com
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https://www.youtube.com/watch?v=vLV4EDBtuas
Quotes I've made that I never expected to be excerpted... 🤣
Perry analogizes many people's experience of writing to passing a kidney stone and then contrasts it with me talking about the Mozart composing/cow peeing analogy.
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- May 2021
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www.washingtonpost.com www.washingtonpost.com
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Blakemore, E. (n.d.). New diabetes cases linked to covid-19. Washington Post. Retrieved February 11, 2021, from https://www.washingtonpost.com/health/2021/02/01/covid-new-onset-diabetes/
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- Oct 2020
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www.itv.com www.itv.com
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Long-term effects of Covid include damage to heart, liver, kidneys. (2020, September 29). ITV News. https://www.itv.com/news/2020-09-29/long-covid-long-term-effects-of-coronavirus-include-damage-to-heart-liver-kidneys-oxford-study-reveals
Tags
- symptom
- recovery
- is:news
- heart
- COVID-19
- long-term impact
- lang:en
- liver
- clinical outcome
- research
- organ damage
- kidney
- medicine
Annotators
URL
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- Aug 2020
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academic.oup.com academic.oup.com
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Yan, Q., Zuo, P., Cheng, L., Li, Y., Song, K., Chen, Y., Dai, Y., Yang, Y., Zhou, L., Yu, W., Li, Y., Xie, M., Zhang, C., & Gao, H. (n.d.). Acute Kidney Injury Is Associated With In-hospital Mortality in Older Patients With COVID-19. The Journals of Gerontology: Series A. https://doi.org/10.1093/gerona/glaa181
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- May 2020
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www.thelancet.com www.thelancet.com
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Jordan, R. E., & Adab, P. (2020). Who is most likely to be infected with SARS-CoV-2? The Lancet Infectious Diseases, S1473309920303959. https://doi.org/10.1016/S1473-3099(20)30395-9
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- Apr 2019
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Klotho-deficient mice have accelerated aging phenotypes, whereas overexpression of Klotho in mice extends lifespan. Klotho is an anti-aging single-pass membrane protein predominantly produced in the kidney, with shedding of the amino-terminal extracellular domain into the systemic circulation. Circulating levels of soluble Klotho decrease with age, and the klotho gene is associated with increased risk of age-related diseases. The three forms of Klotho protein have distinct functions. Membrane Klotho forms a complex with fibroblast growth factor (FGF) receptors, functions as an obligatory co-receptor for FGF23, which is involved in aging and the development of chronic diseases via regulation of Pi and vitamin D metabolism. Secreted Klotho functions as a humoral factor with pleiotropic activities including regulation of oxidative stress, growth factor signaling, and ion homeostasis. Secreted Klotho is also involved in organ protection. The intracellular form of Klotho suppresses inflammation-mediated cellular senescence and mineral metabolism. Herein we provide a brief overview of the structure and function and recent research about Klotho.
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- Oct 2017
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Local file Local file
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Renally cleared PEGylated proteins or their metabolites may accumu-late in the kidney, causing formation of PEG hydrates that interfere with normal glomerular filtration. In addition, animals and humans can be induced to make antibodies to PEG9,10
kidney accumulation, anti-peg antibodies
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