5,190 Matching Annotations
  1. Feb 2021
    1. plasma

      Plasma is a yellowish liquid component of blood that holds the blood cells of whole blood in suspension. It is the liquid part of the blood that carries cells and proteins throughout the body.

    2. gastrointestinal (GI) tract

      The GI tract is a series of hollow organs that form a long tube from the mouth to the anus. The organs within the tract include the mouth, esophagus, stomach, small intestine, large intestine, and anus.

    3. Biomacromolecules

      Biomacromolecules are the building blocks of life. The different macromolecules are: Proteins, Lipids, Carbohydrates, and Nucleic Acids. Each of these macromolecules are responsible for different biological functions within the body and the cells

  2. Dec 2020
  3. Oct 2020
  4. Sep 2020
  5. Jul 2020
    1. Body copy, body text, or sometimes just plain body or text refers to themain block of text that you read, as opposed to headlines, subheads, titles,etc. Body text is usually set between 9- and 12-point type with 20 percentadded space between the lines.

      body copy, body text

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    1. mantle

      A part of Earth’s interior that lies between the dense, extremely hot core and the thin outer layer, known as the crust. It is made up of a thick, rocky shell that constitutes 84% of Earth’s volume. In geologic time, it behaves as a viscous fluid.

    2. continental plume–related basalts

      Both ocean island basalts and continental plume-related basalts come from deep within the mantle. OIBs intruded into oceanic (basaltic) crust, whereas continental plumes intrude into continental crust (for example, Deccan traps in India).

    1. “Janus heads”

      Janus was a Roman god and doorkeeper to the heavens. Relevant here, Janus was usually depicted with two heads, one facing the past and the other towards the future.

    2. β-catenin antagonist adenomatous polyposis coli

      Adenomatous polyposis coli, or APC, is gene that plays many roles, including acting as a tumor suppressor. APC has also been found to play a role in cell division and directing cells where to go once division takes place. In order to do its job, APC directs β-catenin in the Wnt signaling pathway.

      Read more in the Journal of Cell Science. The PDF is also available in the "Related content" tab.

    3. RNA interference (RNAi)

      A mechanism used by both plant and animal cells to silence a gene using a double-stranded DNA molecule. DNA is converted into the smaller RNAi molecules used to turn genes off. Scientists are now able to use this natural process to turn off genes they are studying so they can learn more about their function.

    1. secondary challenge

      A second exposure to the same threat. The immune system is, under certain conditions, able to remember threats it has encountered before and react to them more quickly and effectively upon each subsequent exposure.

    1. channelrhodopsins

      This family of proteins is employed to activate neurons by driving cations (including sodium, calcium, hydrogen, and potassium) into the cell and causing the membrane potential to become more positive, leading to depolarization.

    2. halorhodopsins

      Halorhodopsins and bacteriorhodopsins typically inactivate neurons by driving chloride ions into the cell or hydrogen ions out of the cell and causing the membrane potential to become more negative, leading to hyperpolarization.

    1. Error bars

      A graphical representation (usually lines through a point on the graph that run parallel to one of the axes) showing the amount of uncertainty there is in the location of that point. All scientific data collection includes uncertainty; error bars allow researchers to show how confident they are in their results. Large error bars mean there is a lot of uncertainty (lower confidence), whereas smaller error bars mean there is less uncertainty.

    2. β

      A statistical term, the Greek letter beta, refers to the probability that you can accept the null hypothesis (which states that values affirmation has no effect) when in fact the null hypothesis is wrong.

    3. standardized test

      Any form of an exam that requires all people taking the test to answer the same questions and is scored the same way in all cases, so that comparisons can be made between all people who take the test. These are typically multiple choice tests taken by large populations of students (for example: all 8th grade students in the United States).

    4. psychological threat

      Any outside force (real or perceived) that challenges a person's values, beliefs, or sense of self.

      Stereotype (or identity) threat is a subset of psychological threat in which a person feels they will be judged according to common prejudices about some aspect of their identity (for example: race, ethnicity, or gender).

  6. Jun 2020
    1. silencing

      Turning a gene off so that it does not go through transcription and translation (gene expression) which prevents the production of its protein product (β-catenin) being made by the cell.

    2. constitutive degradation

      The regulated breakdown of a cell or cellular product, which is used to control gene expression and ultimately cellular function. In this case, the breakdown of APC leads to an increase in β-catenin.

    3. homeostasis

      The ability or tendency of an organism to maintain internal stability. This includes maintaining certain ranges of physiological processes such as temperature, pH, or ions such as calcium.

    1. placental mammals

      Members of this group of mammals (which includes humans) carry the developing fetus in the uterus, where the placenta facilitates the exchange of nutrients and wastes between the mother and the fetus.

    2. crevasse splay

      These are floodplain deposits made when the river broke through its natural flood banks. Heavier sediments are deposited closer to the river channel, while lighter sediments, such as sand and silt, are deposited farther away from the channel.

    3. dicotyledonous (dicot)

      This is one of the two groups angiosperms are traditionally divided into. A number of traits distinguish dicots from the other group, the monocotyledons (monocots). The seeds of dicots contain two embryonic seed leaves; monocot seeds contain one.

  7. Apr 2020
    1. reproductive isolation

      Means that the species cannot breed to produce fertile offspring because of some barrier. That barrier could be geographic, behavioral, or some other type. A well-known animal that is reproductively isolated is the mule.

    2. linkage disequilibrium

      This term means that the association of certain alleles at different loci is not random. Essentially, certain alleles of certain genes are often linked together and found in these combinations in the Big Birds.

    3. genetic drift

      Occurs when the frequency of alleles in an organism changes due to chance. Genetic drift (sometimes referred to as drift) is strongest in small populations such as the one studied here, because chance (random sampling) strongly affects the alleles present in the population.

    4. transgressive segregation

      When hybrid offspring show traits that are more extreme than those of the parents. For example, when a hybrid plant offspring is much taller than, or much shorter than, either of the parent plants.

    1. dextran perfusion

      Definition: A polysaccharide glucan that is medically used to reduce blood viscosity.

      For the paper: Dextran perfusion is based on flowing a dextran solution through the tube/pipe to determine whether it is hollow (allows fluid flow), and transports fluids as expected.

    2. cell-laden hydrogels

      Hydrogels loaded with live cells.

      For the paper, this is an appealing option that helps engineering potential tissue constructs with biomimetic structure and function. Cell-laden hydrogel is a promising scaffolding system for engineering artificial bone, cartilage, cardiac and neural tissues.

    3. LIVE/DEAD staining confirmed high viability

      Staining that is a fluorescence assay (as shown in image on Panel E) which shows cell viability, that is whether the cells are dead or live. The live cells emit green light where the dead cells emit red light.

    4. thermoreversible

      Whose properties can be changed back and forth by increasing or decreasing temperature.

      For the article, specific thermoreversible hydrogels form a gel when cooled and return to a viscous fluid state when exposed to heat.

    5. micro–computed tomography (μCT)

      Micro-computed tomography (Micro-CT) is a 3D imaging technique utilizing X-rays to see inside an object, slice by slice. It is similar to a CT scan, but on a micro-scale. Micro-CT provides high resolution 3D imaging of the interior structure of materials and biological samples without having to cut the samples.

    6. micro–computed tomography

      Micro-computed tomography (Micro-CT) is a 3D imaging technique utilizing X-rays to see inside an object, slice by slice. It is similar to a CT scan, but on a micro-scale. Micro-CT provides high resolution 3D imaging of the interior structure of materials and biological samples without having to cut the samples.

    7. tri-leaflet valves

      The aortic valve of the human heart typically contains three leaflets or cusps, hence called the tri-leaflet valve. When the valve opens it allows blood to exit the left ventricle into the aorta. Once closed, blood movement stops. In the case of a dysfunction, the tri-leaflet valve is repaired or replaced by a surgery. The technology described in this article provides a promising approach to create artificial implants for these surgeries.

    8. pH-driven gelation

      Hydrogels are 3D networks of hydrophilic polymers that can hold a lot of water while still maintaining structure. They resemble tissue structure when scaffolded and can nurture cell growth and vessel formation. Hydrogels can be assembled by chemical processes. In this study, authors used pH-driven assembly (gelation).

    9. micro–computed tomography (μCT)

      Micro-computed tomography (Micro-CT) is a 3D imaging technique utilizing X-rays to see inside an object, slice by slice. It is similar to a CT scan, but on a micro-scale. Micro-CT provides high resolution 3D imaging of the interior structure of materials and biological samples without having to cut the samples.

    1. A negative Nb anomaly characterizing the involvement of subducted material is present in all the trace-element patterns of our studied samples. This anomaly implies that a recycled crustal component, and not the ambient mantle, dominates the trace-element budget in the fluid inclusions.

      Negative Nb anomalies are characteristic of subducted material. Subducted material includes continental-sources sediments from the ocean floor that gets subducted into the mantle. The trace element patterns look more like the crust than the mantle, which means that the fluid inclusions' trace element record is not recording any mantle processes.

    2. kimberlite

      A kind of intrusive, igneous rock that is formed deep inside the Earth’s interior. Kimberlite tends to move upwards via the upper mantle and lower and upper crusts, ultimately reaching the surface of the Earth. When the rocks move up, they carry diamonds inside them, thereby becoming an important source of diamonds.

    3. slab subduction

      A slab is a part of the tectonic plate which undergoes subduction. Subduction is a geological phenomenon occurring at the junction between two tectonic plates. This involves pushing one plate below the other, so much so that the sinking plate (usually the denser one) protrudes into the Earth’s mantle.

    4. mid–ocean ridge basalts

      The mid-ocean ridge is one of the largest chain of volcanic mountains on Earth, with 90% of the mountains submerged underneath the ocean. A type of basaltic rock originating from volcanic eruptions in this region is known as mid-ocean ridge basalt.

      Mid-ocean ridges occur where two tectonic plates pull apart and the mantle below wells up and then rapidly cools due to the interaction with the ocean's cold water. This is what makes up oceanic crust.

    5. shallow crustal contamination

      This occurs when magma inside the Earth's mantle gets polluted by small amounts of crustal rocks—that is, rocks from Earth's crust. Shallower crustal rocks are more felsic, which means they contain more feldspar and quartz.

    1. hydraulically amplified self-healing electrostatic (HASEL) actuators

      A device which generates movement from electrical energy. The device consists of liquid segments which helps amplifying force generation and heals itself in case of an electrical breakdown.

  8. Mar 2020
    1. endoscopic overtube

      An endoscopic overtube is a sleeve-like device designed for both upper and lower endoscopic procedures. During upper endoscopy it is designed to protect the hypopharynx from the trauma of repeated intubations, the airway from aspiration, and the esophagus during extraction of sharp foreign bodies.

    1. soft actuators

      a lightweight, affordable, and easily customizable device component consisting of flexible material that converts energy into mechanical movement in order to move/control a part of the device

    2. resonant frequency

      Simply put, resonant frequency is the natural frequency at which it is easiest to get an object to vibrate. Most objects have several resonance frequencies, such as stringed musical instruments that vibrate at their resonance frequencies when plucked or struck, and their vibrations against the surrounding air produce sound. This type of resonance is found when an object is in equilibrium with acting forces and could keep vibrating for a long time under perfect conditions.

    1. continental plume–related basalts

      When large stretches of land are covered by lava generated from a massive volcanic eruption, a type of basaltic lava is created. Sometimes, these eruptions are also caused by movement of tectonic plates in the lithosphere. Such events when combined with abnormally hot rock in the Earth's mantle (mantle plume), give rise to continental plume-related basalts.

  9. Feb 2020
    1. ACTIVITY 2: ASYNCHRONOUS COMMUNICATION TOOLS

      a·syn·chro·nous /āˈsiNGkrənəs/ Learn to pronounce adjective 1.(of two or more objects or events) not existing or happening at the same time. 2.COMPUTING•TELECOMMUNICATIONS of or requiring a form of computer control timing protocol in which a specific operation begins upon receipt of an indication (signal) that the preceding operation has been completed.

      In telecommunications, asynchronous communication is transmission of data, generally without the use of an external clock signal, where data can be transmitted intermittently rather than in a steady stream. Any timing required to recover data from the communication symbols is encoded within the symbols.

      wikipedia

    1. ectothermic

      Commonly called "cold-blooded", this term describes an animal that regulates its body temperature using external energy sources. For example, this is the reason why many reptiles sunbathe.

    2. gestation time

      The period of time that viviparous animals (those that give live birth and do not lay eggs) will carry a developing embryo. The length of this period will vary depending on species; for example humans have a gestation period of 40 weeks, whereas rabbits only take about a month.

    3. scaling coefficient

      Ecologists often use equations to try to describe animal behavior. A "scaling coefficient" is a number by which a variable is multiplied, which is used here to say that temperature (the variable in this case) will cause a larger change in the behavior of prey (large scaling coefficient) than predators (small scaling coefficient).

    4. trevally

      Caranx ignobilis, the "Giant trevally" is called out as an animal that has some key similarities and differences in behavior from the blacktip reef sharks at the center of this study.

      While both are apex predators from the Phylum Chordata, the trevally is a bony fish (Class Actinopterygii) while the shark is a cartilaginous fish (Class Chondrichthyes)

    5. serial correlation

      Also known as autocorrelation, this is a phenomenon that occurs within datasets such as a time series in which the data points are not independent of each other. For example, the temperature recorded one minute is very likely to be similar to the temperature that was recorded for the previous time point because these time points have a relationship to each other, as the temperature will only change as quickly between them as the underlying physics allow. This phenomenon has consequences for some statistical analyses that researchers must correct for to avoid generating spurious results.

    6. teleosts

      An infraclass of the class Actinopterygii, this classification includes most ray-finned fishes found in the world today, with only a few exceptions of ancient fish which branched off earlier in evolutionary history.

    7. tonic immobility

      Many animals "play dead" in response to a stress or threat, but this trance-like state in sharks is thought to be connected to mating since they typically have few predators to feel threatened by. It typically takes 15 minutes for this effect to wear off and has little or no lasting health consequences for the shark.

    8. temporal resolution

      How many measurements are made over a period of time. A measurement is said to be continuous if it is being constantly tracked, whereas discrete measurements are taken periodically at a time interval that the scientists have determined is frequent enough to answer their research question.

    9. backreefs (2–3 m depth, high vertical relief coral, good visibility) which transition to forereefs

      This illustration of the anatomy of a barrier reef shows the relative position and depth of the backreef and forereef to the lagoon found at the center of an atoll:

    10. Palmyra

      Located in the Pacific, south of Hawaii: With no permanent residents, this is a United States Minor Outlying Island that is part of the largest marine protected area in the world: the Pacific Remote Islands Marine National Monument.

    11. behaviourally thermoregulate

      Behaviors performed to control the temperature of an organism such as basking in the sun or seeking shelter.

      An example of turtles basking in the sun to increase their body temperature:

    12. thermal niche

      The temperature conditions within which an organism has the best chance of thriving. This is one of several factors that determine the ecological niche of an organism, which describes how its behavior and habitat choice play a specific role in the context of the larger ecosystem that it is a part of.

    13. enzyme kinematics

      Enzymes perform many important functions in our bodies (such as digestion) and have a temperature at which they can perform optimally. Temperatures that are higher or lower will require more energy to perform the same task. Keeping your body, and the enzymes that it contains, at an optimal temperatures is a way to maximize the efficient use of energy.

    14. crepuscular

      Refers to things that happen during the twilight hours (dawn and dusk). This is in contract to "nocturnal" things that happen at night or "diurnal" things that happen during the day. Crepuscular animals such as deer, bears, and housecats tend to be the most active during these time periods.