noble lie noble deception دروغ شریف

for - answer - Denis Noble - to Michael Levin - question - What percentage of genetic vs non-genetic information passed down to germ line from embryogenesis onwards ? - a very large fraction is epigenetic inheritance indeed.

for - question - Michael Levin to - Denis Noble - percentage of genetic vs non-genetic information passed down to germ line from embryogenesis onwards

for - evolution - work to identify non-DNA information passed down to germ line - millions of permutations - fluorescence technique applied to only a few at a time - tedious work - Denis Noble

for - evolution - epigenetic AND new DNA can BOTH be incorporated into the germ line - Denis Noble

for - evolution - viruses and other organisms - inject information into germ line throughout evolution - Denis Noble

for - evolutionary biology - Weissman barrier - refuted by modern research - Denis Noble

for - Weismann Barrier - disputed by Darwin himself, who believed that the body sends information to the germ line to pass on to the next generation - Denis Noble

for - quote - DNA simply does not replicate like a crystal. You have to have a living organism to enable it to do so. - Denis Noble

for - quote - myth - Richard Dawkin myth - recreate entire organism from DNA - not possible - Denis Noble

quote - myth - Richard Dawkin myth - recreate entire organism from DNA - not possible - Denis Noble - (see below) - As Richard Dawkins told me two years ago in a debate with him: - "Denis, we could inscribe your DNA in blocks of granite, - the C's G's A's and T's, - and we' keep those blocks of granite for 10,000 years and then we'll be able to recreate you." - I said no you can't - why not? - Well, where would you get my mother's egg cell, as it was in1936 - Well you can see that the point here, it led people to a very simplistic idea that from DNA you could automatically recreate a person, an organism exactly as it is in its first, Incarnation if you like - We can all be reincarnated as many times as we wish!<br /> - Well, one one might sort of wish to be a bit of a Buddhist in all of this and get away with that, - but I don't think even the Buddhists would accept that that was the way they were going to do it if they do it at all

for - DNA replication accuracy - 1 in 10,000 - too high for successful replication - another higher level mechanism to correct for these errors - need a whole body for that - Denis Noble

for - Systems perspective - integrate reductionism with global properties - Denis Noble - multi scale competency architecture - Denis Noble - adjacency - multi-scale competency architecture - Michael Levin - Denis Noble advocates for

adjacency - between - multi-scale competency architecture - Michael Levin - Denis Noble advocates for - adjacency relationship - Michael's multi-scale competency architecture is another way to sum up what Denis is saying

for - quote - Hodgkin cycle - example of connection between global property and molecular properties - Denis Noble

for - evolutionary biology - Denis Noble - journey from reductionist to non-reductionist - ion channel and cell membrane work - connects to bioelectricity in the entire body

for - Denis Noble - background - early work on ion channels and cell membranes

for - book - Dance to the Tune of Life - Denis Noble

for - interview - Michael Levin - Dennis Noble

for - from - Denis Noble - Michael Levin interview

from - Denis Noble - Michael Levin interview - https://hyp.is/W2sK1qilEe-9MKdyybb_oA/www.youtube.com/watch?v=AJjIlu9tem8

for - adjacency - Buddhist teachings - Four Noble Truths - life and death - mortality salience - terror management technique

adjacency - between - Buddhist teachings - Four Noble Truths - life and death - mortality salience - terror management technique - adjacency relationship - The Four Noble Truths are: - the recognition of inherent suffering - the cause of suffering - understanding the cause of suffering - the cessation of suffering - and are really - a way to deal with mortality salience and therefore - a terror management technique

for - critique of - Gene Centricity - Denis Noble

from - youtube -Evolution 2 Podcast Interview - Denis Noble - Book - Understanding Living Systems - https://hyp.is/-EuWvBYHEe-t9xtn9h1dhA/docdrop.org/video/oHZI1zZ_BhY/

for - health advice - aging well - Denis Noble

health advice - aging well - ll if you want to age well do something! - It can be - dancing - music - swimming - whatever but do something - That's the first bit of advice to those who want to make sure that they stay on top

for - critique - of Watson & Cricks DNA - agency of organisms

critique - of Watson & Cricks DNA - agency of organisms - Watson & Cricks advocated the now disproven idea that causality is only one direction - from genes to - proteins to - functionality of living organisms - when in fact, it goes the other way, giving the high level living organism agency

for - question - impact of climate change on male and female population distribution of the biosphere

question - impact of climate change on male and female population distribution of the biosphere - How will climate change affect the proportion of males and females of the many species that are and will be impacted by dramatic temperature changes?

for - individual / collective gestalt - gene centrism - paradigm shift - adjacency - mistake of 20th century biology - reductionism - separating organism from environment - individual / collective gestalt, individual / environment gestalt - quote - mistake of 20th century biology - Ray Noble - key insight - mistake of 20th century biology- Ray Noble

quote - mistake of 20th century biology - Ray Noble - (see below)

• I think one of the other mistakes that have been made in biology of the 20th century
  • was to treat organisms as if they existed within an environment that was sort of like some nebulous box as it were
  • and you could study the organism by taking it out
  • and you study it in isolation
• It's the beginning of reductionism in a sense because
  • you taken it away from the environment but the organism has an intimate relationship with the environment
• It's feeding both
  • to the environment and
  • from the environment
• What is that environment?
  • That environment in large part is
    • other organisms of the same species but
    • other organisms of different species
• and it's in a continuous bubble of change
• It's like a cauldron of change
• So the big question for life is
  • how do you maintain yourself in this cauldron of change?
• You cannot do it by standing still
• You have to respond to it
  • so it's not surprising therefore that you find that you know organisms have mechanisms for responding to those changes

adjacency - mistake of 20th century biology - between - reductionism - separating organism from environment - individual / collective gestalt, - individual / environment gestalt - adjacency relationship - The mistake that 20th century biology has made is in - ascribing too much power to the gene, and - minimizing the role of epigenetics - Focusing the majority of attention and resources on the genes of the organism, and - defocusing attention on the organisms (epigenetic) interactions with the environment, including both - biotic elements and - abiotic elements - It's not the case that the genes are the major determinant factor and the epigenetics play a minor role - It IS the case that epigenetics play an equally important role in transmitting and assimilating features into the genome - The individual organism is intertwingled with its environment and with other living organisms - The individual / collective gestalt and the individual / environment gestalt is the appropriate unit of study

for - progress trap - genetic engineering - Denis Noble

for - Denis Noble - Ready Noble - evolutionary biology - critique of Richard Dawkins Selfish Gene theory - critique of gene centrism - book - Understanding Living Systems - human agency

summary - In this informative interview, brothers Denis and Ray Noble discuss their new book - Understanding Living Systems, and - dispel the 70 year old narrative of Gene centrism and the selfish gene as determining the high level behaviour of living organisms

for - quote - genes don't control Richard Dawkins - Ray Noble

for - quote - the age of reason became unreasonable - Ray Noble

quote - the age of reason became unreasonable - Ray Noble - (see below)

• The Age of Reason became unreasonable
  • in the sense of treating us as machines
• Reason requires openness ,
  • it doesn't require a closed view of life and of humanity

for - quote - human agency - Ray Noble

quote - (see below)

• It had to give us something which all the other organisms didn't have which was
  • a cell that was different
  • a mind that was different
• that gave us agency
  • but denied it to other organisms
  • and that unfortunately I think persisted

for - purpose in nature - exorcism of - Ray Noble - quote - gene centered view - organisms as machines - exorcism - Ray Noble - gene centered view

for - quote - progress trap - speed of cultural evolution - Ray Noble

for - recombination of proteins in higher level proteins - from - youtube - Evolution 2 podcast interview - book - Understanding Living Systems - Denis Noble - Ray Noble

from - youtube - Evolution 2 podcast interview - book - Understanding Living Systems - Denis Noble - Ray Noble - https://hyp.is/OttWABYFEe--gLNFyeNyTw/docdrop.org/video/oHZI1zZ_BhY/

for - Oded Rechavi - neurobiology - gene centrism - critique - from - youtube podcast interview - book - Understanding Living Systems - Ray Noble - Denis Noble

summary - Rechavi performed experiments with C Elegan and demonstrated that it possesses a type of neuron that - produces RNA that in response to elevated temperature change is transmitted to reproductive cells so that the offsprings encode it in the genome, and it is better adapted to deal with elevated temperatures

question - How many species do this? Is it generally found throughout nature?

from - outube podcast interview - book - Understanding Living Systems - Ray Noble - Denis Noble - https://hyp.is/OUlGVBXrEe-iaBeZhH_4DQ/docdrop.org/video/oHZI1zZ_BhY/

for - quote - reductionism has failed - Denis Noble

for - follow up - paper - Could physiology rescue genomics?

to - Could physiology rescue genomics? - https://hyp.is/bslQ-BVVEe-hgF-rrNmjrA/academic.oup.com/biolinnean/article/139/4/357/6604006

for - adjacency - progress trap - Crispr - gene therapy - Denis Noble - human genome project

adjacency - between - human genome project - gene therapy - Crispr - progress trap - adjacency relationship - The idea that we can find specific causal relationships between genes and disease and use gene therapy to cure disease, - an envisioned goal of the human genome project - can be very dangerous because - usually one gene collaborates with many other genes to bring about an effect - If we don't know all the relationships, we can bring about a progress trap

for - comparison - human vs AI robot - Denis Noble

for - quote - Darwin would never have been a Neo-Darwinian - Denis Noble

for - metaphor - genes - musical scores - Denis Noble

for - quote - being wrong - Denis Noble

quote - Being wrong - Denis Noble - If we didn't have people who were wrong - we wouldn't be where we are

for - physiology rescues evolutionary biology - Denis Noble

from - youtube - IAI interview - Why Dawkins is Wrong - Denis Noble

for - paper - Physiology restores purpose to evolutionary biology - Denis Noble - Raymond Noble - year - 2023

from - youtube - IAI interview - Why Dawkins is wrong - Denis Noble - https://hyp.is/eqKOYhVVEe-XVKuwMtOTTg/docdrop.org/video/dCLRKP9NW8I/

for - molecular biology - paradigm shift - living system - 4 common misunderstandings - book - Understanding Living Systems - 4 common misunderstandings

4 common misunderstandings of living systems - 1. The central dogma of molecular biology - one way causation - Genes (DNA) to - proteins to - organism - 2. The Weismann Barrier - 3. DNA as self-replicator - 4. Separation of Replicator (DNA) and Vehicle (Living cell) are completely separate

for - quote - Denis Noble - quote - baby not born selfish

for - book - Biology Beyond the Genome - author - scientist - biologist - Denis Noble - book - Understanding Living Systems

for - Keith Baverstock - paper - The Gene and Appraisal

from - youtube - Biology Beyond the Gene - Denis Noble - https://hyp.is/UrvwdhVDEe-QWrPAx9y1aw/docdrop.org/video/bzXFSufDDn8/

In den USA besteht seit langem eine Netzwerk, in dem PR-Firmen mit Unternehmen der Fossilindustrie zusammenarbeiten, Dabei werden u.a. durch gefakete Kampagnen und die Gründung von Umweltgruppen die eigentlichen Stakeholder der Desinformation versteckt. In einem Hearing eines Unterausschusses des Repräsentantenhauses wurden die Praktiken von PR-Firmen aufgedeckt. https://www.desmog.com/2022/09/14/house-committee-pr-climate-disinformation/

https://MarkNoble.com

https://tedgioia.substack.com/p/what-can-we-learn-from-barnes-and

...and if the West sides with Taiwan if China decides to invade it, we will see a repeat of Putin's strategy of limiting export of vital noble gases. Team human doesn't work well when we cannot collaborate

Russia supplies 30% of the global chip industry with neon, argon and helium, necessary for chip manufacturing.

The idea of the "noble savage" can be traced back to early French encounters with indigenous Americans who felt that because the men occupied themselves with hunting and war that they were more like the French noblemen who employed themselves in similar pursuits.

I find it very interesting that they refer to Mansa Musa and Musse Melly. I wouldn’t have understood they were referring to the same person if it wasn’t for the fact they stated about his riches and wealth. In addition, it confirms the fact that he was very wealthy which is stated in many texts. He was wealthy for extracting of riches, but he also was influential leader in Africa.

Bear in mind that this "ownership" is common practice with Amazon, Apple, Google, Kobo, Barnes and Noble, and other ones as well.

It's not this way with non-DRM books, that you can download, and reuse as with physical books.