385 Matching Annotations
  1. Dec 2022
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    Systematic analysis of ADP-ribose detection reagents and optimisation of sample preparation to detect ADP-ribosylation in vitro and in cells
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    biorxiv.org/content/10.1101/2022.02.22.481411v1
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    Drosophila pVALIUM10 TRiP RNAi lines cause undesired silencing of Gateway-based transgenes
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    biorxiv.org/content/10.1101/2022.08.12.503771v2
  4. Nov 2022
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    Actin binding domain of Rng2 strongly inhibits actin movement on myosin II HMM through structural changes of actin filaments
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    biorxiv.org/content/10.1101/2020.04.14.041046v4
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    Miro GTPase domains regulate assembly of the mitochondrial motor-adaptor complex
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    biorxiv.org/content/10.1101/2022.05.13.491728v1
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    Improving the computation efficiency of polygenic risk score modeling: Faster in Julia
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    biorxiv.org/content/10.1101/2021.12.27.474263v1
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    Structure of mammalian V-ATPase with the TLDc domain protein mEAK7 bound
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    biorxiv.org/content/10.1101/2021.11.03.466369v2
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    Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish
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    biorxiv.org/content/10.1101/2021.12.22.473872v1
  10. Oct 2022
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    https://biorxiv.org/cgi/content/10.1101/2022.03.06.483172
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    biorxiv.org/content/10.1101/2022.03.06.483172v1
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    Replication-associated inversions are the dominant form of bacterial chromosome structural variation
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    biorxiv.org/content/10.1101/2022.02.15.480581v1
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    Contribution of the Golgi apparatus in morphogenesis of a virus induced cytopathic vacuolar system
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    biorxiv.org/content/10.1101/2022.03.14.484265v1
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    Regulation of Liprin-α phase separation by CASK is disrupted by a mutation in its CaM kinase domain
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    biorxiv.org/content/10.1101/2022.04.21.489014v1
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    Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions
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    biorxiv.org/content/10.1101/2022.04.03.486870v1
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    Synthetic evolution of herbicide resistance using a T7 RNAP-based random DNA base editor
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    biorxiv.org/content/10.1101/2021.11.30.470689v1
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    Evaluation of CA repeat arrays as targets for MeCP2 function in the brain
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    biorxiv.org/content/10.1101/2022.04.26.489598v2
  18. Sep 2022
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    Meiotic DNA breaks activate a streamlined phospho-signaling response that largely avoids protein level changes
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    biorxiv.org/content/10.1101/2022.02.24.481857v1
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    Human gene function publications that describe wrongly identified nucleotide sequence reagents are unacceptably frequent within the genetics literature
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    biorxiv.org/lookup/doi/10.1101/2021.07.29.453321
  21. Aug 2022
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    Decreasing pdzd8-mediated mitochondrial-ER contacts in neurons improves fitness by increasing mitophagy
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    biorxiv.org/content/10.1101/2020.11.14.382861v1
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    Islet Gene View - a tool to facilitate islet research
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    biorxiv.org/content/10.1101/435743v3
  24. www.biorxiv.org www.biorxiv.org
    Resolution of the curse of dimensionality in single-cell RNA sequencing data analysis
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    biorxiv.org/content/10.1101/2022.05.02.490246v1
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    CFTR modulator response measurements in subjects with cystic fibrosis using 2D differentiated nasal epithelia converted into spheroids
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    biorxiv.org/content/10.1101/2021.07.20.453105v2
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    A minimal hepatocyte growth factor mimic acting as a powerful agonist of the MET receptor tyrosine kinase for regeneration of epithelial tissues and organs.
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    biorxiv.org/content/10.1101/2020.07.20.212654v3
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    Drosophila insulator proteins exhibit in-vivo liquid-liquid phase separation properties
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    biorxiv.org/content/10.1101/2022.05.27.493687v1
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    ScRNA-seq Expression of APOC2 and IFI27 Identifies Four Families of Alveolar Macrophage Superclusters in Cystic Fibrosis and Healthy BALF
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    biorxiv.org/content/10.1101/2022.01.30.478325v3
  29. www.biorxiv.org www.biorxiv.org
    ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1
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    biorxiv.org/content/10.1101/2021.12.22.473898v2
  30. Jul 2022
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    LncRNA RUS shapes the gene expression program towards neurogenesis
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    biorxiv.org/content/10.1101/2022.02.17.480853v1
  32. Jun 2022
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    Negative curvature-promoting lipids instruct nuclear ingression of low autophagic potential vacuoles
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    biorxiv.org/content/10.1101/2021.06.26.450031v1
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    OXSR1 inhibits inflammasome activation by limiting potassium efflux during mycobacterial infection
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    biorxiv.org/content/10.1101/2021.04.21.440692v1
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    Genetic and compound screens uncover factors modulating cancer cell response to indisulam
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    biorxiv.org/content/10.1101/2021.12.20.473451v1
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    Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms to control cell motility and neurite outgrowth.
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    biorxiv.org/content/10.1101/2021.10.27.466197v3
  37. May 2022
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    Molecular insights into RNA recognition and gene regulation by the TRIM-NHL protein Mei-P26
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    biorxiv.org/content/10.1101/2021.09.20.461029v1
  39. Apr 2022
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    Tricalbin proteins regulate plasma membrane phospholipid homeostasis
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    biorxiv.org/content/10.1101/2021.06.04.447076v1
  41. www.biorxiv.org www.biorxiv.org
    Polycomb Group Ring Finger Protein 6 suppresses Myc-induced lymphomagenesis
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    biorxiv.org/content/10.1101/2021.12.02.470967v1
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    Quantitative analysis of nuclear pore complex organization in Schizosaccharomyces pombe
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    biorxiv.org/content/10.1101/2021.08.11.455278v1
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    TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis
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    biorxiv.org/content/10.1101/2021.10.27.466063v1
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    https://biorxiv.org/cgi/content/10.1101/2021.10.18.464926
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    biorxiv.org/content/10.1101/2021.10.18.464926v1
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    Conserved exchange of paralog proteins during neuronal differentiation
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    biorxiv.org/content/10.1101/2021.07.22.453347v1
  46. Mar 2022
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    AGO1 regulates major satellite transcripts and H3K9me3 distribution at pericentromeric regions in mESCs
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    biorxiv.org/content/10.1101/2021.07.26.453733v2
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    GROWTH-RATE DEPENDENT AND NUTRIENT-SPECIFIC GENE EXPRESSION RESOURCE ALLOCATION IN FISSION YEAST
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    biorxiv.org/content/10.1101/2021.03.16.435638v1
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    The expression of essential selenoproteins during zebrafish development requires SECIS binding protein 2-like
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    biorxiv.org/content/10.1101/2021.11.01.466845v1
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    Stress-induced tyrosine phosphorylation of RtcB modulates IRE1 activity and signaling outputs.
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    biorxiv.org/content/10.1101/2020.03.02.972950v5
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    ETV2 regulates PARP-1 binding protein to induce ER stress-mediated cell death in tuberin-deficient cells
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    biorxiv.org/content/10.1101/2021.11.08.467714v1
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    Quantitative Profiling of Adaptation to Cyclin E Overproduction
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    biorxiv.org/content/10.1101/2021.07.26.453751v3
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    https://biorxiv.org/cgi/content/10.1101/2021.09.08.459430
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    biorxiv.org/content/10.1101/2021.09.08.459430v1
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    https://biorxiv.org/cgi/content/10.1101/2021.04.23.440619
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    biorxiv.org/content/10.1101/2021.04.23.440619v2
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    Structural basis of membrane recognition of Toxoplasma gondii vacuole by Irgb6
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    biorxiv.org/content/10.1101/2021.07.01.450801v1
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    Redundant and specific roles of EGFR ligands in the ERK activation waves during collective cell migration of MDCK cells
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    biorxiv.org/content/10.1101/2021.05.25.445569v1
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    Nonsense-mediated mRNA decay utilizes complementary mechanisms to suppress mRNA and protein accumulation
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    biorxiv.org/content/10.1101/2021.05.24.445486v1
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    Recruitment of Scc2/4 to double strand breaks depends on γH2A and DNA end resection
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    biorxiv.org/content/10.1101/2021.07.09.451733v1
  59. Feb 2022
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    Refining the domain architecture model of the replication origin firing factor Treslin/TICRR
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    biorxiv.org/content/10.1101/2021.07.24.453613v1
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    Small disulfide loops in peptide hormones mediate self-aggregation and secretory granule sorting
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    biorxiv.org/content/10.1101/2021.08.20.457087v1
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    Cis-Regulatory Hubs: a Relevant 3D Model to Study the Genetics of Complex Diseases with an Application to Schizophrenia
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    biorxiv.org/content/10.1101/2021.06.22.449467v2
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    Nucleotide Biosynthesis Links Glutathione Metabolism to Ferroptosis Sensitivity
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    biorxiv.org/content/10.1101/2021.07.14.452394v1
  64. Jan 2022
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    Rbfox1 is required for myofibril development and maintaining fiber-type specific isoform expression in Drosophila muscles
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    biorxiv.org/content/10.1101/2021.05.09.443278v1
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    https://biorxiv.org/cgi/content/10.1101/2021.02.04.429604
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    biorxiv.org/content/10.1101/2021.02.04.429604v2
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    Bimodal fibrosis in a novel mouse model of bleomycin-induced usual interstitial pneumonia
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    biorxiv.org/content/10.1101/2021.03.18.435059v1
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    Electron Cryo-Tomography Structure of Axonemal Doublet Microtubule from Tetrahymena thermophila
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    biorxiv.org/content/10.1101/2021.07.13.452106v1
  69. Dec 2021
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    Loss of SET1/COMPASS methyltransferase activity reduces lifespan and fertility in Caenorhabditis elegans
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    biorxiv.org/content/10.1101/2021.06.07.447374v1
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    Artemisinin-independent inhibitory activity of Artemisia sp. infusions against different Plasmodium stages including relapse-causing hypnozoites
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    biorxiv.org/content/10.1101/2021.08.10.455849v1
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    Comparative poly(A)+ RNA interactome capture of fission yeast RNA exosome mutants reveals insights into RNA biogenesis
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    biorxiv.org/content/10.1101/2020.07.01.181719v3
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    Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy.
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    biorxiv.org/content/10.1101/2021.04.28.441730v1
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    Chromosome length and gene density contribute to micronuclear membrane stability
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    biorxiv.org/content/10.1101/2021.05.12.443914v1
  75. Nov 2021
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    Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline
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    biorxiv.org/lookup/doi/10.1101/2021.07.29.454392
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    A multifaceted role of progranulin in regulating amyloid-beta dynamics and responses
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    biorxiv.org/lookup/doi/10.1101/2021.04.12.439509
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    The Th1 cell regulatory circuitry is largely conserved between human and mouse
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    biorxiv.org/lookup/doi/10.1101/2021.01.11.426266
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    The structure and flexibility analysis of the Arabidopsis Synaptotagmin 1 reveal the basis of its regulation at membrane contact sites
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    biorxiv.org/lookup/doi/10.1101/2021.04.09.438084
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    Quantitative Proteomics Identifies PTP1B as Modulator of B Cell Antigen Receptor Signaling
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    biorxiv.org/lookup/doi/10.1101/2021.03.30.437652
  81. Oct 2021
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    Transcriptomic analysis reveals niche gene expression effects of beta-hydroxybutyrate in primary myotubes
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    biorxiv.org/lookup/doi/10.1101/2021.01.19.427259
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    MKP-1 modulates Ubiquitination/Phosphorylation of TLR signaling
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    biorxiv.org/lookup/doi/10.1101/2021.06.10.447995
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    Non-canonical activation of the ER stress sensor ATF6 by Legionella pneumophila effectors
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    biorxiv.org/lookup/doi/10.1101/2020.06.26.174185
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    OrtSuite - from genomes to prediction of microbial interactions within targeted ecosystem processes
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    biorxiv.org/lookup/doi/10.1101/2021.06.04.447094
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    A dynamical extracellular matrix coat regulates moruloid-blastuloid transitions of ovarian cancer spheroids
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    biorxiv.org/content/10.1101/2020.07.03.186155v1
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    Resf1 deletion reduces the efficiency of embryonic stem cell self-renewal and germline entry
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    biorxiv.org/content/10.1101/2021.05.25.445589v2
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    Glucocorticoid receptor activation induces gene-specific transcriptional memory and universally reversible changes in chromatin accessibility
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    biorxiv.org/content/10.1101/2021.01.05.425406v1
  89. Sep 2021
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    Non-cell autonomous choroid plexus-derived sAPPα regulates adult hippocampus proliferation and plasticity
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    biorxiv.org/content/10.1101/734103v2
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    Evaluating CRISPR-based Prime Editing for cancer modeling and CFTR repair in intestinal organoids
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    biorxiv.org/content/10.1101/2020.10.05.325837v1
  92. Jul 2021
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    Edem1 activity in the fat body regulates insulin signalling and metabolic homeostasis in Drosophila
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    biorxiv.org/lookup/doi/10.1101/671305
  94. www.biorxiv.org www.biorxiv.org
    Integrative profiling of early host chromatin accessibility responses in human neutrophils with sensitive pathogen detection.
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    biorxiv.org/content/10.1101/2020.04.28.066829v1
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    A phosphoproteomic approach reveals that PKD3 controls phenylalanine and tyrosine metabolism
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    biorxiv.org/content/10.1101/2020.07.20.211474v1
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    Stepwise transmigration cascade of T and B cells through the perivascular channel in lymph node high endothelial venules
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    biorxiv.org/content/10.1101/2020.12.20.423079v1
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    Proteomics characterisation of the L929 cell supernatant and its role in BMDM differentiation
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    biorxiv.org/content/10.1101/2020.08.20.259515v2
  98. www.biorxiv.org www.biorxiv.org
    Fast but not furious: a streamlined selection method for genome edited cells
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    biorxiv.org/content/10.1101/2021.01.22.427783v1
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    Dynamic closed states of a ligand-gated ion channel captured by cryo-EM and simulations
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    biorxiv.org/content/10.1101/2021.01.04.425171v1
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    Microglia show differential transcriptomic response to Aβ peptide aggregates ex vivo and in vivo
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    biorxiv.org/content/10.1101/2021.03.02.433544v1
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    IL-13 deficiency exacerbates lung damage and impairs epithelial-derived type 2 molecules during nematode infection
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    biorxiv.org/content/10.1101/2020.10.14.337949v1
  102. www.biorxiv.org www.biorxiv.org
    Human IFITM3 restricts Chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction
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    biorxiv.org/content/10.1101/2020.09.11.292946v1
  103. www.biorxiv.org www.biorxiv.org
    Vaccinia virus hijacks ESCRT-mediated multivesicular body formation for virus egress
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    biorxiv.org/content/10.1101/2020.07.15.203935v1
  104. May 2021
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    Gametic specialization of centromeric histone paralogs in Drosophila virilis
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    Dynamic m6A methylation facilitates mRNA triaging to stress granules
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    biorxiv.org/content/10.1101/357012v1
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    DHX15 regulates CMTR1-dependent gene expression and cell proliferation
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    biorxiv.org/content/10.1101/113209v1
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    Co-existing feedback loops generate tissue-specific circadian rhythms
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    biorxiv.org/content/10.1101/304451v1
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    Multi-region proteome analysis quantifies spatial heterogeneity of prostate tissue biomarkers
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    biorxiv.org/content/10.1101/250167v1
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    The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo
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    biorxiv.org/content/10.1101/284737v1