Aortic dissection typically presents acutely with sudden, severe tearing chest or back pain, often described as lancinating in quality. [5-6] Approximately 50% of patients with thoracic aortic aneurysm may progress to dissection without timely intervention. [5] In contrast, thoracic aortic aneurysm is usually asymptomatic and discovered incidentally during physical examination or imaging for other indications. [5]
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- Recent evidence suggests that inflammatory biomarkers may aid differentiation. The neutrophil-to-lymphocyte ratio (NLR) shows high diagnostic accuracy for distinguishing dissection from controls (AUC 0.933), while the fibrinogen-to-d-dimer ratio best differentiates dissection from aneurysm (AUC 0.898, sensitivity 77%, specificity 84%). [10] D-dimer levels below 500 ng/mL make acute aortic syndrome unlikely in low-risk patients
- CT angiography is the imaging modality of choice for differentiating these conditions in the emergency setting, with very high sensitivity and specificity for acute aortic syndromes
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- Aug 2022
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Halstead, I., Lewis, G., & McKay, R. (2021). Opposition to Novel Biotechnologies: Testing An Omission Bias Account. PsyArXiv. https://doi.org/10.31234/osf.io/4ef7m
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Fan, Y., Orhun, A. Y., & Turjeman, D. (2020). Heterogeneous Actions, Beliefs, Constraints and Risk Tolerance During the COVID-19 Pandemic (Working Paper No. 27211; Working Paper Series). National Bureau of Economic Research. https://doi.org/10.3386/w27211
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publications.iass-potsdam.de publications.iass-potsdam.de
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Ball, D., Humpherson, E., Johnson, B., McDowell, M., Ng, R., Radaelli, C., Renn, O., Seedhouse, D., Spiegelhalter, D., Uhl, A., & Watt, J. (2019). Improving Society’s Management of Risks. A Statement of Principles. Collaboration to explore new avenues to improve public understanding and management of risk (CAPUR). https://publications.iass-potsdam.de/pubman/faces/ViewItemFullPage.jsp?itemId=item_5039889_3
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