Cluster 3 reported the lowest median number of symptoms and the least associated disability of the 3 clusters, despite having the highest proportion of severe initial COVID-19 disease and undergoing review earlier after onset of COVID-19 symptoms. Fatigue and shortness of breath were the most commonly reported symptoms, but median MRC score was normal, indicating mild dyspnea-related impairment, and this cluster had the lowest proportion of emergency department attendance. Fatigue is well recognized postinfection, persisting in 27% of those with atypical infections managed in the community at 3 months postdiagnosis [23], so it is plausible that this cluster represents individuals within the normal realm of recovery from an atypical viral illness, which may have useful prognostic consequences for individuals within this cluster.
Cluster 3.