GroupID: None

KindredID: 17

DiseaseAssertion: VHL

GroupSize: 10

GroupNumberMales: N/A

GroupNumberFemales: N/A

GroupEthnicity: American Admixed /Latino

GroupAgeRange: N/A

GroupInfo: 10 members of a South American family expressed this c.183C>G mutation.

GroupPresentingHPOs: HP:0010797, HP:0009711, HP:0005584 (hemangioblastoma, retinal capillary hemangioma, renal cell carcinoma)

GroupHPOFreeText: All 10 family members had a central nervous system hemangioblastoma. One also had a retinal angioma. Five had renal carcinoma. One patient per family with renal tumour <3 cm under follow up detected by imaging.

GroupNotHPOs: HP:0002894, HP:0002666 (neoplasm of the pancreas, pheochromocytoma )

GroupNotHPOFreeText: N/A

GroupPreviousTesting: N/A

PreviouslyPublished: N/A

SupplementalData: N/A

Variant: P61= (183C>G)

LegacyVariant: N/A

CaseProblemVariantFreeText: N/A

ClinVarID: 135951 https://www.ncbi.nlm.nih.gov/clinvar/variation/135951/

CAID: N/A

gnomAD: 0.0009632 https://gnomad.broadinstitute.org/variant/3-10183714-C-G

VariantEvidence: N/A

MutationType: synonymous_variant

CivicName: P61=(c.183C>G)

MultipleGeneVariants: Germline, VHL, Partial Deletion

GroupID: None

KindredID: 16

DiseaseAssertion: VHL

GroupSize: 4

GroupNumberMales: N/A

GroupNumberFemales: N/A

GroupEthnicity: American Admixed /Latino

GroupAgeRange: N/A

GroupInfo: Four members of a South American family expressed this 462-95T>A mutation.

GroupPresentingHPOs: HP:0010797, HP:0002666 (hemangioblastoma,pheochromocytoma)

GroupHPOFreeText:Two family members had hemangioblastoma of the central nervous system. Three had pheochromocytoma.

GroupNotHPOs: HP:0002894, HP:0009711, HP:0005584 (neoplasm of the pancreas, retinal capillary hemangioma, renal cell carcinoma )

GroupNotHPOFreeText: N/A

GroupPreviousTesting: N/A

PreviouslyPublished: N/A

SupplementalData: N/A

Variant: c.464-94T>A

LegacyVariant: IVS2-95T>A

CaseProblemVariantFreeText: N/A

ClinVarID: 1201249 https://www.ncbi.nlm.nih.gov/clinvar/variation/1201249/?oq=1201249&m=NM_000551.4(VHL):c.464-94T%3EA

CAID: N/A

gnomAD: N/A

VariantEvidence: N/A

MutationType: intron_variant

CivicName: R167Q(c.500G>A) and c.464-94T>A

MultipleGeneVariants: Germline, VHL, c.500G>A (Arg167Glu)

GroupID: None

KindredID:9

DiseaseAssertion: VHL

GroupSize: 3

GroupNumberMales: N/A

GroupNumberFemales: N/A

GroupEthnicity: American Admixed/Latino

GroupAgeRange: N/A

GroupInfo: Three members of a South American family expressed this c.344delA mutation.

GroupPresentingHPOs: HP:0010797, HP:0009711, HP:0005584 (hemangioblastoma, retinal capillary hemangioma, renal cell carcinoma)

GroupHPOFreeText: N/A

GroupNotHPOs: HP:0002894, HP:0002666 (neoplasm of the pancreas, pheochromocytoma )

GroupNotHPOFreeText: N/A

GroupPreviousTesting: N/A

PreviouslyPublished: N/A

SupplementalData: N/A

Variant: p.H115Pfs*44 (c.344delA)

LegacyVariant: N/A

CaseProblemVariantFreeText: N/A

ClinVarID:N/A

CAID: CA70049370 https://reg.clinicalgenome.org/redmine/projects/registry/genboree_registry/allele?hgvsOrDescriptor=NM_000551.3%3Ac.344delA

gnomAD: N/A

VariantEvidence: N/A

MutationType: minus_1_frameshift_variant

CivicName: H115Pfs*44(c.344delA) and P61=(c.183C>G)

MultipleGeneVariants: Germline, VHL,c.c.183C>G (p.Pro61Pro)

GroupID: None

KindredID: 17

DiseaseAssertion: VHL

GroupSize: 10

GroupNumberMales: N/A

GroupNumberFemales: N/A

GroupEthnicity: American Admixed /Latino

GroupAgeRange: N/A

GroupInfo: 10 members of a South American family expressed this mutation.

GroupPresentingHPOs: HP:0010797, HP:0009711, HP:0005584 (hemangioblastoma, retinal capillary hemangioma, renal cell carcinoma)

GroupHPOFreeText: All 10 family members had a central nervous system hemangioblastoma. One also had a retinal angioma. Five had renal carcinoma. One patient per family with renal tumour <3 cm under follow up detected by imaging.

GroupNotHPOs: HP:0002894, HP:0002666 (neoplasm of the pancreas, pheochromocytoma )

GroupNotHPOFreeText: N/A

GroupPreviousTesting: N/A

PreviouslyPublished: N/A

SupplementalData: N/A

Variant: Partial Deletion

LegacyVariant: N/A

CaseProblemVariantFreeText: N/A

ClinVarID: N/A

CAID: N/A

gnomAD: N/A

VariantEvidence: N/A

MutationType: Deletion

CivicName: Partial Deletion and P61=( c.183C>G)

MultipleGeneVariants: Germline, VHL, c.183C>G (Pro61Pro)

for - climate crisis - 2023 U.S. poll - demographics - climate communication - 2023 U.S. poll - demographics - climate change - 2023 U.S. poll - demographics - U.S. Hispanic / Latinos - 2023 - high concern about climate crisis - U. S. African American - 2023 - high concern about climate change - U.S. Gen Z - 2023 - high concern about climate change

for - 2024 U.S. elections - polycrisis - 2024 U.S. elections - existential threat to civilization- climate crisis

summary - Some good points: - importance of Black and Latino voters - importance of a third party that can spoil the vote

Why Black And Latino People Still Lag On COVID Vaccines—And How To Fix It. (n.d.). NPR.Org. Retrieved May 6, 2021, from https://www.npr.org/sections/health-shots/2021/04/26/989962041/why-black-and-latino-people-still-lag-on-covid-vaccines-and-how-to-fix-it

8 million Americans slipped into poverty amid coronavirus pandemic, new study says. (n.d.). NBC News. Retrieved October 20, 2020 from https://www.nbcnews.com/news/us-news/8-million-americans-slipped-poverty-amid-coronavirus-pandemic-new-study-n1243762?cid=sm_npd_nn_tw_ma

CNN, S. L. E. (n.d.). More Hispanic workers impacted by Covid-19 in food processing and agriculture workplaces, CDC study finds. CNN. Retrieved 21 October 2020, from https://www.cnn.com/2020/10/20/health/cdc-study-covid-hispanic-workers/index.html

Kamp, P. O. and J. (2020, August 17). WSJ News Exclusive | Covid-19 Deaths Skew Younger Among Minorities. Wall Street Journal. https://www.wsj.com/articles/covid-19-deaths-strike-early-for-many-minorities-11597582801

Book

If you stay at Motel 6, prepare to have your latino-tinged data handed over to the authorities who are looking to harm you permanently.

oh i didnt know that

latinos feel like they get the same racism as black people

Some Latino people think that the country's race categories are not an accurate depiction of what they identify with. This could be seen as extremely racist.

A woman sharing the complexity of her identity as a black latina. Being seen as a "n*gger" by white people, yet not being accepted as black by African Americans, while at the same time her latino family refuses to acknowledge her blackness because of their negative perceptions on blacks.