451 Matching Annotations
  1. Mar 2023
  2. www.biorxiv.org www.biorxiv.org
    New algorithms for accurate and efficient de-novo genome assembly from long DNA sequencing reads
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    biorxiv.org/content/10.1101/2022.08.30.505891v1
  3. Feb 2023
  4. www.biorxiv.org www.biorxiv.org
    Adenylyl cyclase 9 is auto-stimulated by its isoform-specific carboxyl terminal domain and equipped with paradigm-switching mechanisms.
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    biorxiv.org/content/10.1101/2022.06.05.494885v3
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    Lung macrophages utilize cathepsin K-dependent phagosomal machinery to degrade intracellular collagen
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    biorxiv.org/content/10.1101/2022.05.16.492085v1
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    SorCS1 inhibits amyloid-β binding to neurexin and rescues amyloid-β-induced synaptic pathology
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    biorxiv.org/content/10.1101/2022.07.26.501499v1
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    The GET pathway serves to activate Atg32-mediated mitophagy by ER targeting of the Ppg1-Far complex
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    biorxiv.org/content/10.1101/2021.09.20.461067v1
  8. www.biorxiv.org www.biorxiv.org
    Human RNA Nm-MTase FTSJ1: new tRNA targets and role in the regulation of brain-specific genes.
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    biorxiv.org/content/10.1101/2021.02.06.430044v4
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    A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery
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    biorxiv.org/content/10.1101/2022.09.08.507072v1
  10. www.biorxiv.org www.biorxiv.org
    Epigenetic signals that direct cell type specific interferon beta response in mouse cells
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    biorxiv.org/content/10.1101/2022.02.26.481127v1
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    Convergent evolution and horizontal gene transfer in Arctic Ocean microalgae
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    biorxiv.org/content/10.1101/2021.07.31.454568v1
  12. Jan 2023
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    Structural and functional characterization of TraI from pKM101 reveals basis for DNA processing
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    biorxiv.org/content/10.1101/2022.06.02.494495v2
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    Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2
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    biorxiv.org/content/10.1101/2022.08.31.506132v1
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    SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis.
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    biorxiv.org/content/10.1101/2022.02.13.480288v1
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    Epigenetic centromere identity is precisely maintained through DNA replication but is uniquely specified among human cells
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    biorxiv.org/content/10.1101/2022.09.07.506974v1
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    Identifying novel regulators of placental development using time series transcriptomic data and network analyses
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    biorxiv.org/content/10.1101/2022.05.17.492330v1
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    De novo discovery of traits co-occurring with chronic obstructive pulmonary disease
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    biorxiv.org/content/10.1101/2022.07.20.500731v1
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    An isoform-specific function of Cdc42 in regulating mammalian Exo70 during axon formation
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    biorxiv.org/content/10.1101/2022.07.01.498448v1
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    Comparative analysis of MERFISH spatial transcriptomics with bulk and single-cell RNA sequencing
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    biorxiv.org/content/10.1101/2022.03.04.483068v3
  21. www.biorxiv.org www.biorxiv.org
    A synergistic activation of RARb and RARg nuclear receptors restores cell-types specialization during stem cells differentiation by hijacking RARa-controlled program
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    biorxiv.org/content/10.1101/2022.05.31.494116v2
  22. www.biorxiv.org www.biorxiv.org
    Nuclear envelope reshaping around the vacuole determines the morphology of the ribosomal DNA
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    biorxiv.org/content/10.1101/2021.06.23.449658v1
  23. www.biorxiv.org www.biorxiv.org
    Porcine intestinal innate lymphoid cells and lymphocyte spatial context revealed through single-cell RNA sequencing
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    biorxiv.org/content/10.1101/2022.01.09.475571v1
  24. www.biorxiv.org www.biorxiv.org
    Sibling rivalry among the ZBTB transcription factor family: homo vs. heterodimers
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    biorxiv.org/content/10.1101/2021.12.17.472994v2
  25. Dec 2022
  26. www.biorxiv.org www.biorxiv.org
    Stage-specific gene and transcript dynamics in human male germ cells
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    biorxiv.org/content/10.1101/2022.03.22.485121v1
  27. earthcommission.org earthcommission.org
    New Earth Commission Working Group to Focus on the Challenges of Cross-Scale Translation - Earth Commission
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    earthcommission.org/news/earth-commission-news/new-earth-commission-working-group-to-focus-on-the-challenges-of-cross-scale-translation/
  28. www.biorxiv.org www.biorxiv.org
    Cdh5-lineage independent origin of dermal lymphatic vessels revealed by temporally restricted lineage tracing
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    biorxiv.org/content/10.1101/2022.06.08.495310v1
  29. www.biorxiv.org www.biorxiv.org
    Endoplasmic Reticulum membranes are continuously required to maintain mitotic spindle size and forces
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    biorxiv.org/content/10.1101/2022.05.14.491942v1
  30. www.biorxiv.org www.biorxiv.org
    Genome-wide Profiling of Histone Modifications in Plasmodium falciparum using CUT&RUN.
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    biorxiv.org/content/10.1101/2022.08.01.502378v2
  31. www.biorxiv.org www.biorxiv.org
    Systematic analysis of ADP-ribose detection reagents and optimisation of sample preparation to detect ADP-ribosylation in vitro and in cells
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    biorxiv.org/content/10.1101/2022.02.22.481411v1
  32. www.biorxiv.org www.biorxiv.org
    Drosophila pVALIUM10 TRiP RNAi lines cause undesired silencing of Gateway-based transgenes
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    biorxiv.org/content/10.1101/2022.08.12.503771v2
  33. Nov 2022
  34. www.biorxiv.org www.biorxiv.org
    Actin binding domain of Rng2 strongly inhibits actin movement on myosin II HMM through structural changes of actin filaments
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    biorxiv.org/content/10.1101/2020.04.14.041046v4
  35. www.biorxiv.org www.biorxiv.org
    Miro GTPase domains regulate assembly of the mitochondrial motor-adaptor complex
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    biorxiv.org/content/10.1101/2022.05.13.491728v1
  36. www.biorxiv.org www.biorxiv.org
    Improving the computation efficiency of polygenic risk score modeling: Faster in Julia
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    biorxiv.org/content/10.1101/2021.12.27.474263v1
  37. www.biorxiv.org www.biorxiv.org
    Structure of mammalian V-ATPase with the TLDc domain protein mEAK7 bound
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    biorxiv.org/content/10.1101/2021.11.03.466369v2
  38. www.biorxiv.org www.biorxiv.org
    Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish
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    biorxiv.org/content/10.1101/2021.12.22.473872v1
  39. Oct 2022
  40. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2022.03.06.483172
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    biorxiv.org/content/10.1101/2022.03.06.483172v1
  41. www.biorxiv.org www.biorxiv.org
    Replication-associated inversions are the dominant form of bacterial chromosome structural variation
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    biorxiv.org/content/10.1101/2022.02.15.480581v1
  42. www.biorxiv.org www.biorxiv.org
    Contribution of the Golgi apparatus in morphogenesis of a virus induced cytopathic vacuolar system
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    biorxiv.org/content/10.1101/2022.03.14.484265v1
  43. www.biorxiv.org www.biorxiv.org
    Regulation of Liprin-α phase separation by CASK is disrupted by a mutation in its CaM kinase domain
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    biorxiv.org/content/10.1101/2022.04.21.489014v1
  44. www.biorxiv.org www.biorxiv.org
    Gain-of-function genetic screens in human cells identify SLC transporters overcoming environmental nutrient restrictions
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    biorxiv.org/content/10.1101/2022.04.03.486870v1
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    Synthetic evolution of herbicide resistance using a T7 RNAP-based random DNA base editor
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    biorxiv.org/content/10.1101/2021.11.30.470689v1
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    Evaluation of CA repeat arrays as targets for MeCP2 function in the brain
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    biorxiv.org/content/10.1101/2022.04.26.489598v2
  47. Sep 2022
  48. www.biorxiv.org www.biorxiv.org
    Meiotic DNA breaks activate a streamlined phospho-signaling response that largely avoids protein level changes
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    biorxiv.org/content/10.1101/2022.02.24.481857v1
  49. www.biorxiv.org www.biorxiv.org
    Human gene function publications that describe wrongly identified nucleotide sequence reagents are unacceptably frequent within the genetics literature
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    biorxiv.org/lookup/doi/10.1101/2021.07.29.453321
  50. Aug 2022
  51. www.biorxiv.org www.biorxiv.org
    Decreasing pdzd8-mediated mitochondrial-ER contacts in neurons improves fitness by increasing mitophagy
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    biorxiv.org/content/10.1101/2020.11.14.382861v1
  52. www.biorxiv.org www.biorxiv.org
    Islet Gene View - a tool to facilitate islet research
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    biorxiv.org/content/10.1101/435743v3
  53. www.biorxiv.org www.biorxiv.org
    Resolution of the curse of dimensionality in single-cell RNA sequencing data analysis
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    biorxiv.org/content/10.1101/2022.05.02.490246v1
  54. www.biorxiv.org www.biorxiv.org
    CFTR modulator response measurements in subjects with cystic fibrosis using 2D differentiated nasal epithelia converted into spheroids
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    biorxiv.org/content/10.1101/2021.07.20.453105v2
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    A minimal hepatocyte growth factor mimic acting as a powerful agonist of the MET receptor tyrosine kinase for regeneration of epithelial tissues and organs.
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    biorxiv.org/content/10.1101/2020.07.20.212654v3
  56. www.biorxiv.org www.biorxiv.org
    Drosophila insulator proteins exhibit in-vivo liquid-liquid phase separation properties
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    biorxiv.org/content/10.1101/2022.05.27.493687v1
  57. www.biorxiv.org www.biorxiv.org
    ScRNA-seq Expression of APOC2 and IFI27 Identifies Four Families of Alveolar Macrophage Superclusters in Cystic Fibrosis and Healthy BALF
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    biorxiv.org/content/10.1101/2022.01.30.478325v3
  58. www.biorxiv.org www.biorxiv.org
    ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1
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    biorxiv.org/content/10.1101/2021.12.22.473898v2
  59. Jul 2022
  60. www.biorxiv.org www.biorxiv.org
    LncRNA RUS shapes the gene expression program towards neurogenesis
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    biorxiv.org/content/10.1101/2022.02.17.480853v1
  61. Jun 2022
  62. www.civicsoftechnology.org www.civicsoftechnology.org
    Whose interests do teaching machines serve? — Civics of Technology
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    civicsoftechnology.org/blog/whose-interests-do-teaching-machines-serve
  63. www.biorxiv.org www.biorxiv.org
    Negative curvature-promoting lipids instruct nuclear ingression of low autophagic potential vacuoles
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    biorxiv.org/content/10.1101/2021.06.26.450031v1
  64. www.biorxiv.org www.biorxiv.org
    OXSR1 inhibits inflammasome activation by limiting potassium efflux during mycobacterial infection
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    biorxiv.org/content/10.1101/2021.04.21.440692v1
  65. www.biorxiv.org www.biorxiv.org
    Genetic and compound screens uncover factors modulating cancer cell response to indisulam
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    biorxiv.org/content/10.1101/2021.12.20.473451v1
  66. www.biorxiv.org www.biorxiv.org
    Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms to control cell motility and neurite outgrowth.
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    biorxiv.org/content/10.1101/2021.10.27.466197v3
  67. May 2022
  68. www.biorxiv.org www.biorxiv.org
    Molecular insights into RNA recognition and gene regulation by the TRIM-NHL protein Mei-P26
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    biorxiv.org/content/10.1101/2021.09.20.461029v1
  69. Apr 2022
  70. www.biorxiv.org www.biorxiv.org
    Tricalbin proteins regulate plasma membrane phospholipid homeostasis
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    biorxiv.org/content/10.1101/2021.06.04.447076v1
  71. www.biorxiv.org www.biorxiv.org
    Polycomb Group Ring Finger Protein 6 suppresses Myc-induced lymphomagenesis
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    biorxiv.org/content/10.1101/2021.12.02.470967v1
  72. www.biorxiv.org www.biorxiv.org
    Quantitative analysis of nuclear pore complex organization in Schizosaccharomyces pombe
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    biorxiv.org/content/10.1101/2021.08.11.455278v1
  73. www.biorxiv.org www.biorxiv.org
    TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis
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    biorxiv.org/content/10.1101/2021.10.27.466063v1
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    https://biorxiv.org/cgi/content/10.1101/2021.10.18.464926
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    biorxiv.org/content/10.1101/2021.10.18.464926v1
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    Conserved exchange of paralog proteins during neuronal differentiation
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    biorxiv.org/content/10.1101/2021.07.22.453347v1
  76. Mar 2022
  77. www.biorxiv.org www.biorxiv.org
    AGO1 regulates major satellite transcripts and H3K9me3 distribution at pericentromeric regions in mESCs
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    biorxiv.org/content/10.1101/2021.07.26.453733v2
  78. www.biorxiv.org www.biorxiv.org
    GROWTH-RATE DEPENDENT AND NUTRIENT-SPECIFIC GENE EXPRESSION RESOURCE ALLOCATION IN FISSION YEAST
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    biorxiv.org/content/10.1101/2021.03.16.435638v1
  79. www.biorxiv.org www.biorxiv.org
    The expression of essential selenoproteins during zebrafish development requires SECIS binding protein 2-like
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    biorxiv.org/content/10.1101/2021.11.01.466845v1
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    Stress-induced tyrosine phosphorylation of RtcB modulates IRE1 activity and signaling outputs.
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    biorxiv.org/content/10.1101/2020.03.02.972950v5
  81. www.biorxiv.org www.biorxiv.org
    ETV2 regulates PARP-1 binding protein to induce ER stress-mediated cell death in tuberin-deficient cells
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    biorxiv.org/content/10.1101/2021.11.08.467714v1
  82. www.biorxiv.org www.biorxiv.org
    Quantitative Profiling of Adaptation to Cyclin E Overproduction
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    biorxiv.org/content/10.1101/2021.07.26.453751v3
  83. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2021.09.08.459430
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    biorxiv.org/content/10.1101/2021.09.08.459430v1
  84. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2021.04.23.440619
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    biorxiv.org/content/10.1101/2021.04.23.440619v2
  85. www.biorxiv.org www.biorxiv.org
    Structural basis of membrane recognition of Toxoplasma gondii vacuole by Irgb6
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    biorxiv.org/content/10.1101/2021.07.01.450801v1
  86. www.biorxiv.org www.biorxiv.org
    Redundant and specific roles of EGFR ligands in the ERK activation waves during collective cell migration of MDCK cells
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    biorxiv.org/content/10.1101/2021.05.25.445569v1
  87. www.biorxiv.org www.biorxiv.org
    Nonsense-mediated mRNA decay utilizes complementary mechanisms to suppress mRNA and protein accumulation
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    biorxiv.org/content/10.1101/2021.05.24.445486v1
  88. www.biorxiv.org www.biorxiv.org
    Recruitment of Scc2/4 to double strand breaks depends on γH2A and DNA end resection
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    biorxiv.org/content/10.1101/2021.07.09.451733v1
  89. Feb 2022
  90. www.mediamatters.org www.mediamatters.org
    Fox News goes all-in promoting anti-vaccine mandate Canadian truckers
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    1. lucyparfitt16 11 Feb 2022

      Fox News goes all-in promoting anti-vaccine mandate Canadian truckers. (n.d.). Media Matters for America. Retrieved February 11, 2022, from https://www.mediamatters.org/coronavirus-covid-19/fox-news-goes-all-promoting-anti-vaccine-mandate-canadian-truckers

      is:webpage lang:en anti-vaccine anti-mandate vaccine mandate Canada Fox News COVID-19 vaccine protest government trucker convoy airtime Canadian Trucking Alliance Freedom convoy media propaganda USA Omicron social media
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    mediamatters.org/coronavirus-covid-19/fox-news-goes-all-promoting-anti-vaccine-mandate-canadian-truckers
  91. www.biorxiv.org www.biorxiv.org
    Refining the domain architecture model of the replication origin firing factor Treslin/TICRR
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    biorxiv.org/content/10.1101/2021.07.24.453613v1
  92. www.biorxiv.org www.biorxiv.org
    Small disulfide loops in peptide hormones mediate self-aggregation and secretory granule sorting
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    biorxiv.org/content/10.1101/2021.08.20.457087v1
  93. www.biorxiv.org www.biorxiv.org
    Cis-Regulatory Hubs: a Relevant 3D Model to Study the Genetics of Complex Diseases with an Application to Schizophrenia
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    biorxiv.org/content/10.1101/2021.06.22.449467v2
  94. www.biorxiv.org www.biorxiv.org
    Nucleotide Biosynthesis Links Glutathione Metabolism to Ferroptosis Sensitivity
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    biorxiv.org/content/10.1101/2021.07.14.452394v1
  95. Jan 2022
  96. www.biorxiv.org www.biorxiv.org
    Rbfox1 is required for myofibril development and maintaining fiber-type specific isoform expression in Drosophila muscles
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    biorxiv.org/content/10.1101/2021.05.09.443278v1
  97. www.biorxiv.org www.biorxiv.org
    https://biorxiv.org/cgi/content/10.1101/2021.02.04.429604
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    biorxiv.org/content/10.1101/2021.02.04.429604v2
  98. www.biorxiv.org www.biorxiv.org
    Bimodal fibrosis in a novel mouse model of bleomycin-induced usual interstitial pneumonia
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    biorxiv.org/content/10.1101/2021.03.18.435059v1
  99. www.biorxiv.org www.biorxiv.org
    Electron Cryo-Tomography Structure of Axonemal Doublet Microtubule from Tetrahymena thermophila
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    biorxiv.org/content/10.1101/2021.07.13.452106v1
  100. Dec 2021
  101. www.biorxiv.org www.biorxiv.org
    Loss of SET1/COMPASS methyltransferase activity reduces lifespan and fertility in Caenorhabditis elegans
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    Benchmarking a highly selective USP30 inhibitor for enhancement of mitophagy and pexophagy.
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    The structure and flexibility analysis of the Arabidopsis Synaptotagmin 1 reveal the basis of its regulation at membrane contact sites
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    Transcriptomic analysis reveals niche gene expression effects of beta-hydroxybutyrate in primary myotubes
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  124. Jul 2021
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    Integrative profiling of early host chromatin accessibility responses in human neutrophils with sensitive pathogen detection.
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    IL-13 deficiency exacerbates lung damage and impairs epithelial-derived type 2 molecules during nematode infection
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  137. Jun 2021
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    G7 support for pharma monopolies is putting millions of lives at risk
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    1. lucyparfitt16 12 Jun 2021

      G7 support for pharma monopolies is putting millions of lives at risk | Amnesty International. (n.d.). Retrieved June 12, 2021, from https://www.amnesty.org/en/latest/news/2021/06/g7-support-for-pharma-monopolies-putting-millions-of-lives-at-risk/

      is:webpage lang:en COVID-19 G7 G7 Leaders' Summit People's Vaccine Alliance vaccine government UK patent waiving resources campaign vaccine inequity inequity health inequality public health vaccine technology vaccine production funding COVAX pharmaceutical corporation supply finance intellectual property
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  139. May 2021
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    Gametic specialization of centromeric histone paralogs in Drosophila virilis
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    On the Relation of Gene Essentiality to Intron Structure: A Computational and Deep Learning Approach
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    Mapping the micro-proteome of the nuclear lamina and lamin associated domains
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  143. Apr 2021
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    CDCP1 controls compensatory renal growth by integrating Src and Met signaling
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    Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2
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    RNA polymerase backtracking drives the accumulation of fission yeast condensin at active genes
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  170. Oct 2020
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    A meiosis-specific AAA+ assembly reveals repurposing of ORC during budding yeast gametogenesis
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  180. Jul 2020
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    An unexpected contribution of lincRNA splicing to enhancer function.
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    Small molecule inhibitors and a kinase-dead expressing mouse model demonstrate that the kinase activity of Chk1 is essential for mouse embryos and cancer cells
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    A key region of molecular specificity orchestrates unique ephrin-B1 utilization by Cedar virus
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    Pseudomonas aeruginosa lectin LecB impairs keratinocyte fitness by abrogating growth factor signalling
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  189. Jun 2020
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    Plant-microbe co-evolution: allicin resistance in a Pseudomonas fluorescens strain (PfAR-1) isolated from garlic
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    Ubiquitin and SUMO conjugation as biomarkers of Acute Myeloid Leukemias response to chemotherapies
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    Dynamic changes in the regulatory T cell heterogeneity and function by murine IL-2 mutein
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    BACH family members regulate angiogenesis and lymphangiogenesis by modulating VEGFC expression
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    The structure of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR-fold
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  195. Mar 2020
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    Towards a Technology of Solidarity: 10 lessons from Dd's first 10 years
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    1. almereyda 07 Mar 2020
      10. Ally is a Verb Solidarity is an ongoing process, and ally is a verb. Showing up in a good way is something we continually practice, not a destination where we arrive. This is not our unique insight - the concept of ally being a verb, not a noun, has a long history in social justice spaces, and it’s one worth highlighting. When we think of ourselves as “allies” (nouns) we can get complacent by thinking we have arrived, or we can get fragile when we make mistakes that make us question our status as “allies.” When instead we see ourselves as practicing allyship with frontline communities, then we recognize that our goal is to continually listen, learn from and take action in solidarity with our partners.
      alliance
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  197. Nov 2019
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    TAF-ChIP: An ultra-low input approach for genome wide chromatin immunoprecipitation assay
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    Unfolded protein-independent IRE1 activation contributes to multifaceted developmental processes in Arabidopsis
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    Resolving kinesin stepping: one head at a time
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  204. Sep 2019
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    Endogenous RNAi pathway evolutionarily shapes the destiny of the antisense lncRNAs transcriptome
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    let-7 controls the transition to adulthood by releasing select transcriptional regulators from repression by LIN41
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    Kinesin-8B controls basal body function and flagellum formation and is key to malaria parasite transmission
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    XIAP controls RIPK2 signaling by preventing its deposition in speck-like structures
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    Tumor-Intrinsic Response to IFNgamma Shapes the Tumor Microenvironment and Anti-PD-1 Response in NSCLC
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    The WT1-BASP1 complex is required to maintain the differentiated state of taste receptor cells
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    Molecular characterization of Chlamydomonas reinhardtii telomeres and telomerase mutants
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    Molecular characterization of CHAD domains as inorganic polyphosphate binding modules
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    Human DNA polymerase delta is a pentameric complex with dimeric p12 subunit: Implications in enzyme architecture and PCNA interaction
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    PISD is a mitochondrial disease gene causing skeletal dysplasia, cataracts and white matter changes
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    A junction coverage compatibility score to quantify the reliability of transcript abundance estimates and annotation catalogs
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