14 Matching Annotations
  1. Jan 2026
    1. Weak muscles linked to higher dementia risk in middle-aged and older adults
      • Study Overview: Analysis of ~6,000 adults aged 50+ from English Longitudinal Study of Ageing (ELSA) over ~9 years found weaker muscles linked to higher dementia risk, published in Journal of Psychiatric Research.
      • Measurements: Upper body via handgrip strength (dynamometer, adjusted for BMI/weight); lower body via chair stand test (5 rises without arms).
      • Key Findings: Lowest grip strength group had 2.8x higher dementia risk (absolute) and >2x (BMI-adjusted); slowest chair stand had 2.75x higher risk; consistent across age, sex.
      • Robustness: Sensitivity analysis excluding early dementia cases confirmed results; linear relationship between strength decline and risk increase.
      • Possible Mechanisms: White matter hyperintensities, shared neural pathways, chronic inflammation affecting muscles and brain.
      • Limitations: Observational (no causation), self-reported diagnoses, UK white population over 50, no dementia subtypes.
      • Implications: Muscle strength tests for early dementia screening; potential for strength training interventions to support brain health.
  2. Sep 2025
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  9. Mar 2021
    1. Yet sales figures for certain neuro-psychotropic drugs are considerably higher than the incidence of the illnesses for which they are indicated would lead one to expect. This apparent paradox applies above all to neuropsychotropic drugs that have neuro-enhancement properties. The most likely explanation is that neuro-enhancers are currently undergoing millions of self-trials, including in universities – albeit probably not in their laboratories. The ten top-selling psychotropic substances in the USA include anti-depressants, neuroleptics (antipsychotics), stimulants and drugs for treating dementia.
    1. DataBeers Brussels. (2020, October 26). ⏰ Our next #databeers #brussels is tomorrow night and we’ve got a few tickets left! Don’t miss out on some important and exciting talks from: 👉 @svscarpino 👉 Juami van Gils 👉 Joris Renkens 👉 Milena Čukić 🎟️ Last tickets here https://t.co/2upYACZ3yS https://t.co/jEzLGvoxQe [Tweet]. @DataBeersBru. https://twitter.com/DataBeersBru/status/1320743318234562561

  10. Jul 2020
  11. May 2017