10 Matching Annotations
  1. May 2023
    1. Timson printing press at Edwards Brothers Malloy in Ann Arbor, one of only three locations in the United States that meet Library of America’s rigorous production standards. [All LOA books are now printed at Edwards Brothers Malloy.]
  2. Apr 2021
    1. Les jeunes les plus exposés à des difficultés spécifiques devront faire l’objet d’actions de soutien renforcées, et notamment les jeunes relevant de l’ASE (mineurs et jeunes majeurs) et de la PJJ. La question des Mineurs Non Accompagnés (MNA) et des jeunes en errance est explicitée plus spécifiquement dans le PRAPS
  3. Mar 2021
    1. Dafa ànd ak moroom yi àll ba, fori aloom.

      Il est allé dans la brousse ramasser des fruits de Diospyros avec ses camarades.

      dafa -- he/she.

      ànd v. / ànd bi -- to be together, to go together; copulate; going together, fellowship; placenta.

      ak -- and, with, etc.

      moroom mi -- comrade of the same age group, equal, companion, neighbor.

      yi -- the (plural).

      àll bi -- large expanse of uninhabited land, bush; distant, as opposed to home.

      ba -- the (indicates distance).

      for+i (for) v. -- to pick up.

      aloom bi -- edible fruit of Diospyros mespiliformis (aloom gi for the tree).

      https://www.youtube.com/watch?v=nL4iHgp5ejk

  4. Nov 2020
  5. Oct 2020
  6. Sep 2020
  7. May 2019
    1. While more traditional therapies such as chemotherapy and radiotherapy lack tumor specificity targeting all replicating cells, and other immunotherapies have limited scope by relying on the presence of a specific ligand/receptor, oncolytic viruses are postulated to be both specific to neoplastic cells and have an expansive immunostimulatory latitude. The

      Chemo and Radiation lack specificity in targetting cancerous cells, instead targeting a large scope or rapidly dividing cells.

      Immunotherapies are limited to the presence of ligand and receptors for activation.

      Oncolytic viruses are specific to neoplastic (cancerous, specific) cells and have a large amount of immunostimulatory range----> can activate tumor immunity, stimulate immune system......

    1. a genetically engineered or naturally occurring virus that can selectively replicate in and kill cancer cells without harming the normal tissues

      Contrasting to gene therapy, where a virus is used as a mere vector (carrier of a gene), oncolytic virotherapy uses the virus as a drug agent.