Bit confusing, when the previous line says changes will be ignored.

how the WIN site tethers WDR5 to chromatin?

what is myc-TEAD1

With AutoDock and 3kys, I can not reproduce the docking pose provided by this paper

this is strange, as the YAP interface 1 segment is a beta strand, which forms multiple Hbond with TEAD. So how could it be dispensable for TEAD binding?

what is the sequence of the peptide? it might be the peptide 1 in Fig 1D, which shows the strongest binding to TEAD, ~ 200 nM. Peptide 1 contains just the alpha helix and omega loop, so it is possible that the FA binding will affect the beta strand part which is missing in peptide 1

what is the score? calculated by which software the author probably used Schrodinger Sitemap, although they did not mention. but they used Schrodinger to calculated the strain energy and prepare the protein structure

Q: Is this because it's not an issue with taking in glucose, it's an issue with letting go of all the glucose you have saved up?

It's like the difference between generational wealth and binge/purge wealth. On a metabolic level. Oof.

Q: Why would you want to inhibit phosphorylating glucose, trapping it in the cell, when you are stressed out (cortisol)? Why would you want to inhibit it during growth and repair (growth hormone)?

Are they trying to divert glucose to other tissues, selectively inhibiting glucose from being trapped in non-essential tissues?

Q: Why would you take up ketones. Is this just the opposite of when you send out ketones during a glucagon state?

Q: Why though. What do you need K for?

Where can I read more about these constraints?

top 50 molecules are selected. Although the average docking score increases, what about the average ligand efficiency

It's interesting that under my site's origin it lists cookies for other domains. Are these considered 3rd-party cookies or 1st-party cookies written by a 3rd-party script? How is it allowed to set them on my site? Presumably because I loaded a script from their origin.

Loading scripts from other origins allows them to set cookies on which domains? Only their origin? And which cookies can they read?

I am not sure I understand perfectly what was said here, however, if what I believe it is being said is right I think this is a very interesting sentence. Son of God is a statement made by us, which is sufficient by itself but also by greek philosophers? As a reinforcement of this statement?

I would like to look at other texts to see how this compares because, while most writers agree that God is not physical, if they are including Jesus in their definition of God it becomes more complicated because of the Incarnation. I wonder why in this section the author doesn't reference the physical nature of God in the form of Jesus. If the idea of the incarnation was still in dispute at this point, maybe Athenagoras shared beliefs with Docetism?? Or maybe he is just discussing the immaterial God for the sake of supporting his argument that Christians acknowledge on God. What would he make of the father, son, and holy spirit? I will look for more on this further in the text.

try and understand this better. Ask about it in the synchronous meeting?

???

This illustrates a pretty common challenge with joins: you want them to be used for some of the query but not for other of it.

How do you mine gas?

only?

What is the leading \ for? Is that the same as prefixing it with command to ensure no aliases are used?

Found answer here: https://hyp.is/1lBLAiHEEeqP7Sd3rqQLxg/rvm.io/rvm/install

That sounds incredibly high to me. 3000 mg is the absolute maximum intake that could ever be considered 'low' sodium. Under 1500 is usually considered ideal. Would, then, a diet aiming for half the sodium be twice as effective?

This doesn't make sense. Why are double quotes necessary?

Will their telescopes be able to see out that far?

why is that? how do we know for sure that will happen every time.

How was this executed? It must have been a logistical nightmare

Was piracy in this time period always this well-organized and documented?

What are the mechanisms of the system?

okay, answer to previous question above.

Note the differences between risk assessment and risk management. The project would look towards risk assessment and then migrate its focus to risk management potentially, but what then? and how will this transition be smooth/original?

golden.

nice nice

This is the crux of what I should be looking at I guess This is in regards to national strategies. Is this what I need to do?

Risk assessment or assessment of impact?

1) ICS 2) IOT 3) GPS

worthwhile to assess one or all? Followed up question later

This is a remarkable letter from the Dean's office assigning responsibility to a young professor at OSU to head a committee to oversee the relocation of Axis-related college students in the Pacific Northwest and listing institutions that might accept Japanese American college students. Although Italian and German students are named, only the Nisei relocation is "imminent" (and, presumably, the only one that actually occurred). I wonder how the tuition arrangements were to be made, particularly for those who had scholarships, or were paying state school tuition but were being transferred to a private college?

is this why people tend to tell a personal story before giving advice? there have been countless times where i'll be in a weird space, and when i seek advice about X, they'll tell me about Y before laying the actual piece of advice on me.

so does this mean that identity is the centre of story telling? i ask, because what i'm interpreting is that identity is shaped by agency and enhanced by motive.

how can we curate information?

"Why are there beings at all instead of nothing? That is the question." Heidegger is probably quoting Hamlet.

can we do wildcard paths at all?

hmmm... what about client-API architectures where there are no username/pwd pairs?

Did Balbuena argue that music without lyrics was also descended from poetry, or did he just not take that into account? Is this answered later in the text?

I'm confused here too. Contrary and notwithstanding both mean in spite of, but why are they on right after the other. It reads in my mind as a double negative. But I think I understand what they're trying to say. Laws made in pursuance of the Constitution that abide by the "law of the land" are valid, and any law to the contrary of what is said in the Constitution, is not valid.

What question? Is it saying State banks don't have an influence, or do? The next sentence says there's no intention to create a dependence between the Government and the states. So if there was no dependence created, where does that leave state banks?

When they discuss taxation at first in the constitution were they hesitant of the idea because of the American Revolution?

This statement is confusing to me, I am not sure why the idea of amendment is an embarrassment?

What would America be like if we didn't separate into different states and all were under the same laws and regulations?

How do you specify otherwise?

Abstract is a sale's pitch, I would say. It summarizes the whole article, and helps the audiences like you and me, to determine whether/how this work might be relevant.

In the following abstract, identify the research question, highlight it, and state it in your own words (because the authors ask something quite different from what they propose in the beginning).

The canonical size does not allow percentage values, does it?

In the following section, identify and highlight the research question.

Is this why so many variables about students were used in the regression?

How to decide what methods or how many methods we can or should use to do a temporal analysis? The decision should be based on the research question or the norms in this field?

I was curious as whether if analyzing good teaching practices, can we reveal the principles that can guide novice teachers to become better at their teaching considering how to organize learning activity and when to transit?

I'm wondering if this is still true, are most supreme court cases original jurisdiction?

Does the president have to have a solid reason for removal of an officer? Is the president that only one with this power?

Was this before checks and balances came into play? If so was this situation one that led to the concept of checks and balances?

Why don't teachers in high school prepare students for writing college essays?

They mention curriculum a few times being different in public schools and religious schools, I'm wondering what is the difference?

Aside from religion, this statement makes me wonder what other controversial tax exemptions are there?

This statement from Justice Elena Kagan makes me wonder how they would go about making certain money is not spent on religious activity? Does the government have a process in place to see that its funding is spent properly?

This is a really interesting article in so many ways; it speaks to a larger political issue of our time, it uses an innovative method (an experiment!), and it follows a very generic and general structure of a social science research paper. Think of this as an ideal or prototype of social science research.

Is one way better than the other?

Would it really be that easy?

What does predisposed mean?

Is boneheaded really the best way that those kinds of mistakes can be described?

It it a need though or a passion?

What do they mean by the Domino Effect

This is a field correct?

What's this mean?

Is it typical to be used in addition with a exemplification essay. To take it above and beyond in its quality of writing?

What material wealth did the commoners have to seize? Was this a time of looting by government officials from the laboring classes? Does this tend to happen more often than not in times of crisis?

Is it even vaguely possible to be aware of all the times we occupy this position in order to respond to it appropriately? It seems to me like we'll all be constantly failing to recognize that we aren't in a position to make these choices and thus making them anyway. In fact, will we ever occupy a position of rationality? (Perhaps so, going back to the mustard example from earlier.)

But why would rationality be essentially tied up with accountability for a phenomenon or control over it?

This is the big move. It adequately describes how I feel we should approach situations where we reasonably expect to encounter implicit bias even when it doesn't feel like we're being biased. I do wonder, though, precisely how often this would lead to a subject's inability to make a decision rationally? It may be shockingly often.

Can we not distinguish some as epistemically special due to the nature of what kind of assumptions we're using to insulate ourselves from reality, or from where we got those assumptions?

But does she have no evidence? Is recognizing that she's already worried that he's angry enough to warn her that the experience could be misleading and she should put less trust in her perceptual experience?

What determines proper balance? Likely very contextualized. Is ever prior outlook in some way useful or are there some (like vanity, perhaps) which shouldn't ever be given any weight?

Are we sure it's not about the structural mismatch between our minds and reality? Obviously the mental states gained from prior experiences, etc. are necessary for the errors to occur, but I don't think it's possible to isolate the mistakes as not being the result of the way our brain processes this info.

Irrational perception seems to be a psychological phenomenon of misinterpretation on the part of the person doing the perceiving. Most of these causes seem to be related to or are themselves mental states, except for perhaps knowledge. What is it about these states that "get in the way" of an objective perception of the world?

Does each meristem site produce all three types of permanent tissues or are different tissues produced at the different places where meristems are located?

I do not understand this. Does this mean the Xylem stops working when the plant reaches maturity?

Would it be safe to think of this as a plant version of stem cells since they are undifferentiated?

How would / could we handle this situation? Would it be inappropriate to try and talk to parents ourselves?

Does this mean we are looking for a series of numbers?

Are all lines that are not tangent always secant?

Wants it display the country code next to the country name in the dropdown (I would like this too).

What does this mean?

Is he implying that identifying the market actualy happens after developing the product or the service ?

What does "log-bilinear regression" mean exactly?

question interrogates problem of... wow, hard for me to encapsulate in a sentence. How about: Us teachers and other stakeholders need to engage in dialogue/action around equity and NGSS in our own local connections yet be aware of and engage with other local dialogues and furthermore transform/be-transformed-by the emerging, higher level discourse. np

• http://butterfingers.urbanup.com/1280380# :

a clumsy person, especially one who tends to drop things

• But "B" is capitalized: https://www.butterfinger.com/

Is dropping knees not uncommon in PH?

Who are you talking to?

When do Philipino couples bring Butterfingers, randomly or at a specific situation, like a birthday?

Some kinda compromise or what?

surrender to what?

Is kismet a common word in PH?

Why Butterfingers?

To whom?

I hope somebody can answer this question.

This seems like to me the other story we read about a man going on the journey to death, and confronting his different parts along the way. Does anybody know the name of the story I am trying to think of?

Does anybody know who are the slaves in this culture?

are these feature values or actual features?

In that case CrossNet doesn't really learn anything?

I couldn't find what this means. I thought it might be a location, but I was wrong. Does anybody know the answer to this topic?

Student Contribution System = new name for students and the state sharing the cost of tertiary education, with an income-contingent repayment approach (those benefitting the most making the greatest contribution...[what does this mean?])

I'm guessing education employers fund for their employees is excluded from the education this document considers?

? see if this is defined later Also, what's included in 'technical' training here?

Why does he use the word sometimes?

of what religion?

I dunno which mode of knowing he is talking about: a scientist or a sharman?

Is that the Biblical one?

This is an interesting topic to me. Why did they bring up Solomon? Solomon was "the biblical king most famous for his wisdom. In 1 Kings he sacrificed to God, and God later appeared to him in a dream asking what Solomon wanted from God. Solomon asked for wisdom." Do the knights look up to Solomon as an example on how to act and be?

https://en.m.wikipedia.org/wiki/Solomon

Question: could someone explain what this means? What is synthetic about the model?

How do we actually verify the given transaction?

est ce que tu fais référence à une structure en couches successives ? ou tu as juste oublié un mot ? sinon je propose la structure en poupées russes (plus élégante)

Dans quelle mesure il y a pas une veine genettienne ici ?

formatages ?

imaginons que je ne sache pas lire, que donc mon rapport au texte est davantage du déchiffrement (une forme de lecture donc), peut-on encore parler de littéracie ? de texte ? même si mon rapport est un lisible fondé sur du visible, même si je me rapport au texte (ensemble) comme un tableau ?

What are these? This term has showed up more than once.

its weird how people are able to exploit these people legally, and if not legally than how have people not made an effort to stop them?

I wonder if the people at the top of the company even know that this is going on with there "employees"

I cannot understand what is meant by open gray?

how does they made it?

What is AMSTAR assessment? What is the URL where I can find the information?

What is meant by systematic meta-review

what is meant ?

what is the mean?

Are they really helping the poorer countries who need help way more than they do?

"SHE is responsible" Is this BOLD repetition on the page related to oratorical style? It would be interesting to hear this document read aloud, incorporating all the emphases of the upper case letters and rhetorical breaks.

This explains well why we need a long jump, however why not we just start from the place at the beginning of the BIOS?