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DOI: 10.1016/j.xcrm.2025.102506

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DOI: 10.1016/j.celrep.2025.116716

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DOI: 10.1016/j.cell.2025.11.023

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DOI: 10.1016/j.cell.2025.11.023

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What is this?

Pryskyřičný tisk

Jsou k dispozici náhradní díly pro stany Jehlan? Ano, pro stany typu Jehlan jsou k dispozici náhradní díly. Potřebujete je? Kontaktujte nás!

Zvládne jeden člověk sestavit reklamní slunečník? Ano, naše slunečníky se snadno rozkládají a každý si s nimi poradí sám bez jakýchkoli problémů.

Slunečníky

Veletržní stan

there has to be MITKO s.r.o. (CZ) contact + map

Neváhejte se s námi poradit i libovolných detailech Vaší zakázky.

statement by government from appeal

delete

Celý obchodní tým i zákaznický servis je připravený probrat s Vámi libovolné detaily zakázky!

Nejvyšší kvalita bez kompromisů Na naše výrobky se můžete plně spolehnout i za nepříznivého počasí.

Bezkonkurenční záruka Na stanové konstrukce poskytujeme záruku až 5 let. I po jejím uplynutí držíme náhradní díly skladem.

Krátká doba dodání Včetně potisku 10-14 dnů i v plné sezóně!

Proč zvolit MITKO? +CZ text in video Vyrábíme reklamní stany a vybavení, které přitahují zákazníky. Hlavní důraz je kladen na odolnost, spolehlivost a komfortní užívání. Naše výrobky nejsou na jednu sezónu, ale budou Vás provázet na akcích mnoho let. (next paragraph) Veškeré naše výrobky můžete potisknout libovolným designem! Využívám digitální metody potisku s UV odolností barev. (next paragraph) Jako jediní na CZ a SK trhu vyrábíme vybrané typy stanů s odolností vůči větru až do 100 km/h, což máme podloženo statickými výpočty.

1100+

17+

Vyrábíme reklamní stany a eventové doplňky s důrazem na odolnost a spolehlivost. Skupina MITKO je přímým výrobcem všech nabízených produktů! Výrobní proces máme pod kontrolou od A do Z a nečekáme tak na dodávky subdodavatelů. (next paragraph)Na naše výrobky a celkovou spolupráci se spolehají velké nadnárodní společnosti, ale i střední firmy a mikrofirmy.

When I read that “society produces conformity,” it feels like the world around me is constantly telling me who I’m supposed to be. It pushes certain names, labels, and traditions on me, even if they don’t fit who I really am.

society” as a vague force that pressures equally unclear “individuals.” It assumes everyone feels the same pressure and only has two choices: give in or “be themselves.” In reality, social pressure comes from specific sources like friends, family, media, or rules and people respond in many different ways.

Writers should name specific groups instead of pretending the whole world agrees.

College papers require a thesis that someone could disagree with, and paragraphs that flow logically from one to the next.This is the main difference between high school and college writing. The thesis isn’t just a summary it drives the whole argument and keeps the reader interested. The organic structure makes the essay feel like a real conversation or exploration.

High school essays often use three main reasons to support the thesis, each getting its own body paragraph.This shows how formulaic high school essays can be. The order of the reasons doesn’t really matter, so it’s predictable and safe but not very creative.

This section explains that a college thesis shouldn’t just state a fact it should be something someone could disagree with. It makes the essay more interesting and gives it a purpose.

Shows that many students waste space with vague intros

Emphasizes clarity and purpose in introductions. Thought I like this it makes writing feel focused and interesting.

This shows a common writing habit: students often begin with weak or unclear introductions because they think a paper needs a “slow start.” It reminds us that strong, clear opening sentences make a paper more interesting and show confidence in your ideas.

This reminds me that just saying stuff isn’t enough in essays. You need facts or quotes to back up your ideas

I like this because it makes writing feel less like homework and more like sharing your opinion with others.

This is helpful because it shows how to mix what others think with what I think, so my essay has both evidence and my own ideas.

This highlights a common misconception about paragraph structure. While some writing guides promote mini-conclusions, academic writing typically values forward momentum over tidy endings. A paragraph's purpose is to advance the argument set by the key sentence, not to wrap itself up like a small essay

Calling paragraphs “punctuation” reframes them as structural signals rather than other choices. Like commas or semicolons, they guide how readers process relationships among ideas.

This point stresses authorial control. Ending on a quote can let someone else's voice define your argument’s direction or tone. Finishing with your own phrasing ensures you maintain ownership of the analytical thread and guide the reader toward the next point.

Pozáruční servis

I po skončení záruky provedeme jeho kompletní prohlídku a zkontrolujeme, které části se opotřebovaly a vyžadují výměnu. Díly pak po odsouhlasení ceny vyměníme a celý stan Vám pošleme zpět - připravený do akce!

dílů svépomocí

实现CDK6/CDK4选择性的原因在于，CDK6 G-loop的刚性使其在容纳异丙醇基团时产生较高应变能的结果，CDK4的G-loop具有更强的灵活性，通过分子动力学模拟得出。CDK6 G-loop中三个残基（Glu18、Glu21和Lys26）之间存在两个盐桥

阿贝西利苯并咪唑2位甲基的氧化是主要代谢方式

嘧啶环的C-5位取代基朝向守门员残基

CDK4/6在ATP结合口袋的同源性高达92%，利用CDK6的突变体来构建CDK4与化合物的共晶

通过在哌啶环上引入羟基，提升了选择性

降低与CDK2的亲和力的方式为在A环引入一个吡啶，增加与CDK4/6铰链区的His的氢键，而CDK2铰链区的为苯丙氨酸，无法形成额外的氢键

CDK4/6抑制剂造成中性粒细胞减少症的原因在于CDK6在造血功能中的作用

Index cards are important tools, particularly if you're going through a thousand or more a month. I tend toward the cheapest ones I can find and am always half tempted to bulk order them in pallet quantity from somewhere to get a steep discount, especially as I've got filing cabinet storage space for another 40,000 4x6 index cards readily at hand.

I looked more closely at the Wexfords I just picked up and they are made in India. Comparatively my Staples branded cards are also made in India, while the Amazon Basics and Oxford cards are made in the United States.

As for line quality, the most consistent I've seen are the Stockroom Cards designed in California, but made in China. Oxford has been generally solid and Amazon lines have been occasionally hit and miss.

About a year ago, the local Amazon Fresh store had dozens of their 500 card packs listed for an overly reasonable $2.50 each (half a penny per card), so I picked up about 15,000 cards at a time when they were usually in the $12-15 range online. They're presently at a near annual best of $7.45 (about 1.5 cents per card). At $3.50 for 100, the Wexfords ran almost twice as expensive at 3.5 cents per card. I suspect tariffs are likely affecting the price of foreign cards more heavily lately.

I've not really tried out any listed as "flashcards", so I can't comment on the prices or quantities there. Some of the ones I have seen tended to the more expensive side, so I've passed on them.

Good luck in your continued search.

The Banks are the true winners of war, here's a beautiful clip that explains it.

The Collapse of The American Dream Explained in Animation - YouTube

IMDB Link for Memex Reference -> The American Dream (Short 2010) - IMDb

Reminds me of Leviathan and Its Enemies: Mass Organization and Managerial Power in Twentieth-Century America by Samuel T. Francis | Goodreads

Let me see if I got this right,

The Car Companies were bailed out because if they could not pay back their debt it would cause a chain reaction. It wasn't just about the jobs disappearing and causing a chain reaction, it was the effect the bankruptcy would have on the banks balance sheets and how they would have to respond to said balance sheets.

This sounds like a Externality to me, a unaccounted effect on the human lived experience that does not show up int he money documents.

This seems like a loaded statement, let's break it down.

If the laundromats were all independently owned this math would not work. The capacity to leverage oneself to buyout companies is a privilege of a specific caste.

This reminds me of the story about how Pornhub (Mindgeek), being a tech company not a porn company, was a member of this specific caste. Pornhub, like youtube at the time, allowed anyone to upload whatever copyrighted material they wanted to share for free. This put the porn producing companies all out of business because no one bought their product since it was on Pornhub for free. As these porn producing companies went brankupt, Pornhub, with access to cheap debt was able to buy them all up.

Bro I have never seen this concept stated so bluntly. England, Australia, and Canada all have Housing Pricing affordability problems. That probably just means they are mindlessly printing money, which is part of Managed Decline

Yea trumps 50-year mortgages are probably going to mess with housing prices quite a bit. It's subsidizing the elites. I wonder why he decided to do that, do you have any idea why?

Some ideas, * 50 year mortgages reduce monthly payments for working class home buyers, even thought the bank makes way more money * The USA is printing money and this is where some of it has to go * Boomers need exit liquidity, if home prices decide every boomer with a reverse mortgage is gonna end up without a home

I like to think that Blue Collar workers get healthcare in the United States. Do they not? Are there any info graphics or studies that illustrate who in America has what levels of health care coverage?

What would an example of this "shame" bureaucrats might threaten the poors with?

Robert Kiyosaki knows this game quite well and has leveraged himself to 1.2 Billion Dollars in debt.

He likes to say, if you have a million dollar loan and can't pay it back, you have a problem, but if you have a billion dollar loan and can't pay it back, the bank has a problem.

Albion's Seed - Wikipedia

Finitism - Wikipedia, a society with finite resources

Ohhh this right here is the real thesis, there is a caste of people with access to cheap capital and another caste of people without access to cheap capital. These different castes are playing different games but they both operate for survival in the same world.

Do you agree with this interpretation of the text?

There's a name for this trend. Atomization? What name would you give it?

You've Got Mail (1998) - IMDb

Modernity my dude, Modern Urban Living inverts the value of Children, on the farm Children were assets, in cities they are expenses.

I have heard of Curtis Yarvin describe children in Urban settings basically functioning as "expensive furniture" in his Gray Mirror block, I can't find the exact one right now.

This is a financial anecdote I have never heard of. Do you know how I can discover and make these kind of small business investments?

Six Feet Under (TV Series 2001–2005) - IMDb

Not gonna lie, this description of the 13 Reasons Why has me sold on watching the show. I also felt like high school was not preparing her to serve any useful function in society.

If what we learned in highschool was really that useful we would retain some of it, let's get some kids in their late 20's and provide them the exact same tests they did in highschool and see how they do on them.

It's amazing how useful something like Home Ec would be to the average person compared to mindless Science and Math. I do consider "Science and Math" to the average person to be mindless pursuits because their lives after high school don't resonate with what they learned in school.

If people spent as much time learning cooking, not nutrition out of a dam book but actual cooking and nutrition with food that you can actually eat, instead of the Periodic Table I bet Obesity would be less of a problem in the West.

The Golden Notebook by Doris Lessing | Goodreads

What is a "coalitional game"?

Coalitional game theory deals with multi agent dynamics requiring cooperation rather than just raw self interested agents.

Source: Coalitional Game theory - GeeksforGeeks

Ah A Child, she is acting like a child

There has to be a name for this archetype of person, do you know what it might be?

Ancedotal thought, do we know how these credit score algorithms work? Like is there a reference design, design document, open source implementation out there so we can take a look inside the system.

It would be interesting to use this "Open Source Implementation" with agent based modeling

Sounds like a business opportunity to me, compete with the money marts and other short term loan companies online. Leveraging the white listed ex criminals who did the financial literacy course and other "Social Credit" activities makes business sense.

What is a "coalitional game"?

Coalitional game theory deals with multi agent dynamics requiring cooperation rather than just raw self interested agents.

Source: Coalitional Game theory - GeeksforGeeks

This shows professors spend a lot of time grading, not just giving assignments randomly. Knowing this can help students appreciate their effort and take the work more seriously. It reminds us that assignments aren’t busywork—they matter.

Writing for a teacher is hard because you’re trying to explain something you’re still learning to someone who already understands it better than you.

This point is valuable because it clarifies why students frequently find academic writing to be awkward. Although your reader is already familiar with the subject, you are expected to sound confident about concepts you are still learning. It emphasizes how writing for college can be stressful or perplexing because it isn't communication in the real world. Comprehending this discrepancy enables students to unwind and recognize that the difficulty is inherent in the system rather than a reflection of their aptitude.

The fact that early university students did not have classes, assignments, or exams like contemporary students may surprise and intrigue a freshman. Rather, they were treated almost like novice scholars, reading, attending lectures by experts, and interacting directly with eminent intellectuals. This demonstrates how the role of students has completely changed over time and stands in stark contrast to the structured coursework of today.

“Most employers almost 9 out of 10 think colleges should focus more on teaching students how to speak and write clearly.

This sentence introduces the idea of deliberate practice, highlighting the fact that intentional, focused work—rather than just producing more text—is what leads to better writing. This concept is used by the author to support the idea that students should continue honing their writing abilities in college, even if they already write a lot.

So even though you may think or feel that you are overly competent in a college level of reading and writing, yet there has never been a perfect paper done. There is no perfect level or writing or reading there is always going to be a paper thats better so therefore there is alwasy room for improving your skills.

I find this super practical It’s basically teaching that every sentence should show the main actor and action clearly. I can see how using this makes technical writing way easier to read and understand. I need to practice this in my essays to avoid confusing readers.

This is really helpful because it shows that professors don’t want complicated words just to sound smart. Using simple, clear language actually makes your ideas stronger. I sometimes overthink words to sound “fancy,” but this reminds me that clarity is more important than sounding scholarly.

I like this because it reminds me that worrying too much about fancy sentences can actually hurt your writing. It makes sense that if your overall argument is strong, the sentences almost write themselves. It feels less stressful knowing I can fix sentence stuff after I have a solid plan.

Nota Bene

I feel like you can work on the wording here, like use the phrase knowledge base of grassroots initiatives in actual conversation with normal every day people.

I want to win and become a good writer and make people want to dig deeper into my stories and even have a bit of humor at the right times.

I like this idea because it makes the reader want to dive deeper into the story and make it actually interesting.

I never knew this. Now i want to pay attention to more commercials and see if its good ethos.

I like how this is kind of an intro or a little definition to make the rest of this article easier to read.

impotant evadance

key argument

key argment

Key agment

Main Point

Hyperlinking would be beneficial

Hyperlinking it would be beneficial

Hello

Creo que hace falta más hincapié en el aspecto regresivo y hacen falta más que comillas para desarticular la potencia de la palabra "modernización" que, no por nada, es la elegida para presentar esta reforma. Sugiero no usar la palabra modernización a menos que este acompañada por nuestra propia definición que podría ser, simplemente, "retroceso" laboral.

Es interesante esta generalidad desde los bloques (objetos, tipos y relaciones, que se juntan en un grafo). Los Dumems en Cardumem son otra forma de generalización desde el hipertexto programable (gracias al scripting en YueScript) y los metadatos personalizables que permiten las tablas de Lua.

Sin embargo, para disminuir la complejidad y aumentar la practicidad, en Cardumem no apuntamos a tecnologías de la llamada web 3.0, sino que usamos las buenas y confliables web 2.0 con algo de retrofuturismo en los sistemas hipermedia.

I really liked this article, placing human attention in the realm of natural resources extracted by "Investors" is a novel idea I had never heard of before.

The idea of attention as a mineable resource hits really well given the context provided in this article. First presenting the limited resources of Coal, Trees, Fish, and Oil really helps paint a tangible feeling to help put the idea that "Attention is finite".

Not using the word capitalism in the article a single time and instead using "Investor", "MBA Prodigies" really helps paint the picture, I believe Capitalism is a very loaded word and appreciate the word choice.

I think that this as a stand alone piece works great, but it's got me thinking. It speaks to one emotionally which is very important. There is more to be done in digesting the meme, "Attention as a mineable resource". For example, What really is attention, why it is valuable, what are products it defines, what is the history of attention as a mineable resource. These questions would be a good starting off point for future discussion. For example we think of Facebook and Tik tok as attention mining systems, but before the internet we also has TV(Idiot Box), Magazine, Taboilds, and News Papers as systems of mining attention. There's a fun "The Medium is the Message" allegory to be made here I don't quite have the media literacy to articulate.

Isin't tiktok just a Chinese version of Vine?

This reminds me of Soma (Brave New World) - Wikipedia

Limited partnership - Wikipedia

You end up with a population that can't read I guess, what do you think future reader of this article?

So we are basically witnessing the creation of the Borg or is it more like the Matrix? Something seems to be happening

contains the activations from the previous layer (the outputs after applying activation functions)

Weight matrix for layer L

Not correct re Argentina

cut

with model.get_topic_sizes()

Please add Lingyao Li as a co_corresponding author lingyaol@usf.edu

• The Heart of the Active vs. Sedentary Person

  • The heart of an active individual undergoes positive adaptive changes and ages slower compared to the heart of someone with a sedentary lifestyle [00:03:04].
  • In people over 40, a sedentary heart tends to be less elastic, slightly thicker, and fills with blood less efficiently (diastolic dysfunction) [00:03:35].
  • For endurance athletes, the heart’s chambers enlarge (increased volume), which is a positive, physiological change, enabling it to fill and pump blood more effectively [00:04:27].
  • Active people have more elastic arteries, which helps maintain healthy blood pressure. In contrast, inactive people develop stiff, calcified arteries, which increases blood pressure and susceptibility to damage and plaque formation [00:05:24].
  • Exercise promotes the development of collateral circulation (new blood vessels). This helps protect the heart muscle by supplying blood via alternative routes during an event like a heart attack, often resulting in less severe damage [01:06:17].

• Activity and Atherosclerosis

  • Physical activity acts similarly to statins by stabilizing atherosclerotic plaques [00:09:28]. It helps transform soft, rupture-prone (vulnerable) plaques into hard, fibrous, and calcified plaques, significantly reducing the risk of a heart attack or stroke [00:10:14].
  • Plaques do not disappear completely, as no known medicine or diet can "clean out" the arteries; the goal is stabilization and prevention of new plaques [00:09:39].

• The Optimal Protocol for Heart Health

  • Regularity is the absolute key to cardiovascular benefits. The type or intensity of the activity is less important than consistency [01:31:42].
  • Weekend Warrior Principle: Research now shows that completing the required weekly volume of activity (a few hours) over the weekend provides the same health benefits as spreading it out daily [01:52:07], [00:00:08].
  • Intensity Mix: For maximizing health benefits, most of your training should be at a moderate intensity (a pace where you can comfortably hold a conversation, around 5-6 out of 10 on the perceived exertion scale) [01:46:25], [01:46:42].
  • High-Intensity Training (HIT) is effective for saving time, as it achieves the same health effects in a shorter duration, but it does not provide significantly greater health benefits than longer, moderate-intensity training [01:46:01], [01:47:14].

• Non-Training Activity and VO2 Max

  • Non-training activity (e.g., taking the stairs, cleaning, parking further away) is crucial because every movement adds up and counteracts the sedentary nature of modern life [01:18:59].
  • Step Count: Focus on making steps count by including portions of brisk walking or climbing that cause a light sweat or quickened breath [02:22:04]. While optimal step counts vary (8,000–12,000+), any increase from a sedentary baseline (3,000-4,000) provides benefits [02:28:40].
  • VO2 Max and Longevity: Maximal oxygen uptake \(VO_2\) is considered one of the strongest predictors of longevity, as it measures the entire system’s function (lungs, circulation, muscle uptake) [01:34:51].
  • Training at any age builds this "capital," which helps counteract the natural decline in capacity (about 1 MET per decade), ensuring a higher level of functional fitness later in life [01:33:09].

• Regeneration and Safety

  • Regeneration: The greatest health benefits occur between workouts. Exercise provides the stimulus, but the positive changes—like lowering blood pressure and metabolic adjustments—happen during the rest and recovery period [01:50:29], [01:51:25].
  • Monitoring (HRV): Parameters like Heart Rate Variability (HRV) from smartwatches should be treated as supplemental information. They are highly sensitive to stress, illness, and sleep, but they are not a reliable medical indicator. Always listen to your body and your self-assessed fatigue level over a watch [02:55:09].
  • Medical Screening: For people planning very intense training or competitive events, a basic medical check-up is recommended. This should include assessing family history of heart disease, checking risk factors (blood pressure, cholesterol, glucose), and performing an EKG [02:01:15], [02:02:01], [02:07:07]. Avoid self-ordering large, expensive "sports packages" of tests, as they often lead to false-positive results and unnecessary worry [02:03:04].

• Final Key Message

  • The single most important factor for long-term health is regularity. Choose an activity that is enjoyable, sustainable, and that you can imagine yourself doing consistently at 60 or 70 years old [03:09:05].

Concerts reflected youth culture’s optimism and creativity, but also its violence, chaos, and social unrest.

The moon landing showed U.S. technological achievement and victory in the space race against the USSR.

Johnson’s long experience, political skill, and knowledge of Congress allowed him to pass major legislation effectively.

Televised violence shocked viewers, showing peaceful protesters being attacked, highlighting racial injustice in the United States.

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Many whites resisted integration to maintain racial hierarchy and prevent social mixing in schools.

African Americans demanded more equality, challenging segregation and inspiring activism during the 1950s.

Unlike railroads, highways were built for cars, funded by the government, and didn’t increase the national debt.

Better transportation, like highways, allowed more cars, boosting jobs, spending, and overall American wealth.

Marshall Plan rebuilt economies: NATO provided military security—Marshall Plan stabilized Europe more effectively long term.

Beyond ideology, both nations wanted global influence and control over strategic regions and resources.

Unlike the League, the UN included major powers with permanent Security Council seats and veto power.

Kennan believed the USSR’s expansion threatened peace, so the U.S. needed to stop its influence.

Roosevelt’s direct communication helped Americans trust him and support New Deal programs and reforms.

Programs assumed men earned money and women stayed home, limiting women’s access to economic benefits.

Critics felt Roosevelt’s radical programs gave too much federal power, possibly violating the Constitution.

Hoover had experience helping people during crises, so Americans thought he could handle the Depression.

People liked Hoover because he promised more wealth and a better standard of living.

People liked Republicans because they promised safety, steady jobs, and strong business support after the war.

Life was changing fast with new music, movies, and jobs, so voters wanted things to feel familiar again.

People liked this idea because they were tired of war and big changes and wanted life to feel calm and normal again.

This shows that assimilation focused on controlling social structures, but it ignored the deep cultural roots of Native communities, limiting its effectiveness.

This shows that unfair treatment and unfulfilled agreements by the U.S. government created economic hardship and anger among the Dakota people.

Internal divisions made it hard for Populists to maintain a consistent national strategy and message.

This shows that Populists gained support by tapping into widespread frustration with economic inequality and corporate power, giving farmers and laborers a voice against elites.

Investors and managers liked Taylorism because it increased productivity, reduced labor costs, and made output more predictable, which meant higher profits.

This indicates that as industries expanded and machines took on more tasks, individual workers’ specialized skills became less crucial, thereby reducing their bargaining power and making jobs easier to replace.

This shows that the civil war forced the federal government to take on more authority, weakening state power to manage the nation during and after the war.

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update-- 2026

Update-- School/Division (e.g., CCAS) then add LAI employees are not eligible for ACME grants

Add after Status-- ACME grants are distributed through GW payroll services. You must be paid through GW to receive grant funds.*

Monday, March 2, 2026, at 11:59pm.

update Monday, March 2, 2026 at 11:59pm.

update as follows Fall 2026 and Fall 2027(i.e. Fall 2026, Spring 2027, Summer 2027, Fall 2027).

update to "2026"

update to $1450- as stated in current estimates link

SAG⇄E Insights for Learning framework

insights for learning

insight

Insight provided

going to worse and worse

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