As the ATP is consumed, the muscle cells are unable to keep up with the demand for respiration, O2 becomes limiting, and NADH accumulates. Cells need to get rid of the excess and regenerate NAD+, so pyruvate serves as an electron acceptor, generating lactate and oxidizing NADH to NAD+. Many bacteria use this pathway as a way to complete the NADH/NAD+ cycle.

A variety of mechanisms have emerged over the 3.25 billion years of evolution to create ATP from ADP and AMP

Can you state what you know so far about the relationship between NADH/NAD+ and ATP?

There are three large, negative ΔG drops in the cell in the process of glycolysis. We consider these reactions irreversible and are often subject to regulation

June did this, June did that, she savedmoney and helped clean the house and cookedand Connie couldn't do a thing, her mindwas all filled with trashy daydreams.

l. The frat boy who made special trips to Abercrombie & Fitch “waspiecing together a theory about the world,” while the righteous Hsu, who had also started writingfor Asian American newspapers, assumed that whenever he and Ken would make a list of the fewAsian characters on sitcoms, they “were just goofing off and passing time.” But some of Ken’s“theory” seemed to leave its mark on Hsu — even if, like anything whose influence is so profoundit’s subterranean, it manifested less as a doctrine than as a disposi

There was one thing to be done before I left, an awkward, unpleasant thing that perhaps had better have been let alone. But I wanted to leave things in order and not just trust that obliging and indifferent sea to sweep my refuse away. I saw Jordan Baker and talked over and around what had happened to us together, and what had happened afterward to me, and she lay perfectly still, listening, in a big chair. She was dressed to play golf, and I remember thinking she looked like a good illustration, her chin raised a little jauntily, her hair the colour of an autumn leaf, her face the same brown tint as the fingerless glove on her knee. When I had finished she told me without comment that she was engaged to another man. I doubted that, though there were several she could have married at a nod of her head, but I pretended to be surprised. For just a minute I wondered if I wasn’t making a mistake, then I thought it all over again quickly and got up to say goodbye.

I wanted to get somebody for him. I wanted to go into the room where he lay and reassure him: “I’ll get somebody for you, Gatsby. Don’t worry. Just trust me and I’ll get somebody for you—”

I suppose he smiled at Cody—he had probably discovered that people liked him when he smiled. At any rate Cody asked him a few questions (one of them elicited the brand new name) and found that he was quick and extravagantly ambitious.

Oh, I’ve been in several things,” he corrected himself. “I was in the drug business and then I was in the oil business. But I’m not in either one now.” He looked at me with more attention. “Do you mean you’ve been thinking over what I proposed the other night?” Before I could answer, Daisy came out of the house and two rows of brass buttons on her dress gleamed in the sunlight. “That huge place there?” she cried pointing. “Do you like it?” “I love it, but I don’t see how you live there all alone.” “I keep it always full of interesting people, night and day. People who do interesting things. Celebrated people.”

I’d like to just get one of those pink clouds and put you in it and push you around.

She had a bottle of Sauterne in one hand and a letter in the other.

I began to have a feeling of defiance, of scornful solidarity between Gatsby and me against them all.

Which poet or poem has been quoted most often in the effort toget laid?

How did you start writing?

Corliss couldn't help herself. She loved her mother, but her motherwas a bipolar storyteller who told lies during her manic phases andheavily exaggerated during her depressed times. Those lies and ex~aggerations were often flattering to Corliss, so it was hard to com~pletely resent them

We're still Indian.

Much rich treasure he’s bringing back home from Troy 40out of the booty, while we, who went through the selfsameventure as he did, are returning empty-handed!

Go close in there, hero, exactly as I instruct you,and dig out a pit, about a cubit deep and wide,and around it pour a libation to all the dead

So she spoke. I drew the sharp sword from beside my thigh,and charged at Kirkē, as though with intent to kill her.She gave a loud scream, slipped under my charge, embracedmy knees, and, sobbing, addressed me with winged words, saying:‘Who are you? From where? What city? Who are your parents? 325I’m amazed that you drank my drug and were not bewitched!

Her mother, who noticed everything and knew everything and whohadn't much reason any longer to look at her own face, always scolded Connie about it.

If any one have assaulted and plundered a freeman, and it be proved on him, he shall be sentenced to 2500 denars, which make 63 shillings.

My br other is also a physician, and also of high standing,and he says the same thing.

Personally I believe that congenial work, with excitement andchange, would do me good

Nemo me impune lacessit

Looking as if she were alive. I call That piece a wonder, now: Frà Pandolf's hands

When you are feeling calm and nourished, you are going to look forward to your day, and despite howbusy it is, you will prioritize time with friends and family. If you don’t take care of and learn to love yourself,you will never be able to bring your best self to any relationshi

First having read the book of myths, and loaded the camera, and checked the edge of the knife-blade,

whose drowned face sleeps with open eyes whose breasts still bear the stress

I stroke the beam of my lamp slowly along the flank of something more permanent than fish or weed

This is the place. And I am here, the mermaid whose dark hair streams black, the merman in his armored body.

I put on the body-armor of black rubber the absurd flippers the grave and awkward mask.

I am having to do this not like Cousteau with his assiduous team aboard the sun-flooded schooner but here alone.

Andthank God she was there, for I was filled with that icy dreadagain. Everything I did seemed awkward to me, and every-thing I said sounded freighted with hidden meaning. I wastrying to remember everything I'd heard about dope addictionand I couldn't help watching Sonny for signs. I wasn't doing itout of malice. I was trying to find out something about mybrother. I was dying to hear him tell me he was safe.

Tm surprised at Sonny, though

But now, abruptly, I hated him. I couldn't stand the way helooked at me, partly like a dog, partly like a cunning child. Iwanted to ask him what the hell he was doing in the schoolcourtyard.

And he was giving it back, as every-thing must be given back, so that, passing through death, itcan live forever. I saw my mother's face again, and felt, for thefirst time, how the stones of the road she had walked on musthave bruised her feet. I saw the moonlit road where my fa-ther's brother died. And it brought something else back to me,and carried me past it, I saw my little girl again and feltIsabel's tears again, and I felt my own tears begin to rise.

when gods don’t desire it, whocan witness their passage, either coming or going?”

Two roads diverged in a yellow wood,And sorry I could not travel both

Whatever she planted grew as if by magic, and her fame as a grower of .flowers spread over three counties. Because of her creativity with her flow-ers, even my memories of poverty are seen through a screen of blooms-sun-flowers, petunias, roses, dahlias, forsythia, spirea, delphiniums, verbena ...and on and on.

He didn't bother talking much to them, but around his bent headConnie's mother kept picking at her until Connie wished her mother was dead and sheherself was dead and it was all over.

with charm braceletsjingling on their thin wrists; they would lean together to whisper and laugh secretly ifsomeone passed who amused or interested them. Connie had long dark blond hair thatdrew anyone's eye to it, and she wore part of it pulled up on her head and puffed out andthe rest of it she let fall down her back. She wore a pull-over jersey blouse that looked oneway when she was at home and another way when she was away from home

She told the blind man she'd written a poemand he was in it. She told him that she was writing a poemabout what it was like to be an Air Force officer's wife

And then I found myself thinkingwhat a pitiful life this woman must have led.

In time, sheput it all on a tape and sent the tape to the blind man.

Her heart was almost too bignow for her chest and its pumping made sweat break out all over her. She looked out tosee Arnold Friend pause and then take a step toward the porch, lurching. He almost fell.But, like a clever drunken man, he managed to catch his balance. He wobbled in his highboots and grabbed hold of one of the porch posts.

mother's tone was approving, and if Connie's name was mentioned it was disapproving.This did not really mean she disliked Connie, and actually Connie thought that hermother preferred her to June just because she was prettier, but the two of them kept up apretense of exasperation, a sense that they were tugging and struggling over something oflittle value to either of them. Sometimes, over coffee, they were almost friends, butsomething would come up—some vexation that was like a fly buzzing suddenly aroundtheir heads—and their faces went hard with contempt.

He looked at her. He took off the sunglasses and she saw how pale the skin around hiseyes was, like holes that were not in shadow but instead in light. His eyes were like chipsof broken glass that catch the light in an amiable w

They must have been familiar sights, walking around the shopping plaza in theirshorts and flat ballerina slippers that always scuffed the sidewalk,

June did this, June did that, she savedmoney and helped clean the house and cookedand Connie couldn't do a thing, her mindwas all filled with trashy daydreams.

"Oh, her. That dope."

so much land that Connie had never seen before anddid not recognize except to know that she was going to it.

Everythingabout her had two sides to it, one for home and one for anywhere that was not home:

childhood

The mosteffective way to combat procrastination is to use time and project management strategies such as schedules,goal setting, and other techniques to get tasks accomplished in a timely manner.

John is a physician, and perhaps— (I would not say it to a livingsoul, of course, but this is dead paper and a great relief to mymind)— perhaps that is one reason I do not get well faster

It is getting to be a great effort for me to think straight. Justthis nervous weakness, I suppose.

Personally I believe that congenial work, with excitement andchange, would do me good.

Weare a species that needs and wants to understand who we are

“Our students are coming into school every day with greater needs in every aspect of their lives, including around their mental health. But the support just isn’t there to help teachers and staff,” said Bissegger.

l _ou mu~ tell_fil1yone/' my mother said, "what Iam about to tell you. In China your father had a sister whokilled herself. She jumped into the family well. We say thatyour father has all brothers because it is as if she had neverbeen born.

Above: the time to do a production bundle

M. Chirimuuta

The abundance of nonpolar functional groups give lipids a degree of hydrophobic (“water fearing”) character and most lipids have low solubility in water.

“You will say that I was puzzled; but, if you think so, you must have misunderstood the nature of the inductions. To use a sporting phrase, I had not {kk}been once{kk} ‘at fault.’

It takes machine learning to discover and grammatize higher-order motion primitives that exploit the full mobility envelope of a given machine.

testimony about where they were and what they were doing that afternoon.

you are juggling, and everything’s in the air, and you’re frozen.You have to stay there until you’ve eliminated all questions

Or are you only working with cases where you’re pretty sure from the get‑go that the person is‑‑

g machine. Then I rem

From my experience I cannot doubt but that man, when lost to terrestrial consciousness, is indeed sojourning in another and uncorporeal life of far different nature from the life we know, and of which only the slightest and most indistinct memories linger after waking.

I'm cold.cold?TC: Why don't you put on your shirt?RB: (Silence)TC: It's odd about tattoos. I've talked to several hundred men con'viof homicide-multiple homicide, in most cases. The only comdenominator I could find among them was tattoos. A good eighcent of them were heavily tattooed. Richard Speck. York and La...Smith and Hickock.RB: I'll put on my sweater

Vera said:“Does any one - want tea

Surely some one can read Morse. And then they’ll come to take us off. Long before thisevening.”

no, it isn’t coincidence! It’s our murderer’s touch of local colour! He’s a playful beast.Likes to stick to his damnable nursery jingle as closely as possible’

what really I was really interested in was the idea that Marx wasn't really Keen or was sort of hostile to the idea of equality which I'm guessing will come as a surprise to many people

The key is tobe your own best advocate, becauseno one else is obliged to advocate on your behalf.

What can you recall about your birthday parties-the dis-asters, the days of grace, your relatives' faces lit up by birthdaycandles

The first useful concept is the idea of short assignments. Oftenwhen you sit down to write, what you have in mind is anautobiographical novel about your childhood

So you get up and do your morning things, and one thingleads to another, and eventually, at nine, you find yourself backat the desk, staring blankly at the pages you filled yesterday.

Don't worry if what you write is no good,because no one is going to see it.

At such times I could not help remarking and admiring (although from his rich ideality I had been prepared to expect it{w}) a peculiar analytic ability in Dupin. He seemed, too, to take an eager delight in its exercise — if not exactly in its display — and did not hesitate{x} to confess the pleasure thus derived. He boasted to me, with a low chuckling laugh, that most men, in respect to himself, wore windows in their bosoms,(8) and was wont to follow up such assertions by direct and very startling proofs of his intimate knowledge of my own. His manner at these moments was frigid and abstract; his eyes were vacant in expression; while his voice, usually a rich tenor, rose into a treble which would have sounded petulantly but for the deliberateness and entire distinctness of the enunciation. Observing him in these moods, I often dwelt meditatively upon the old philosophy of the Bi-Part Soul,(9) and amused myself with the fancy of a double Dupin — the creative and the resolvent.

An extraordinary burglary — attended by very singular circumstances, and perpetrated by a curious felon — occurred in this town on Monday night.

There is no back passage by which any one could have descended while the party proceeded up stairs.

“The man who ran up against you as we entered the street — it may have been fifteen minutes ago.”

They must, then, have the power of fastening themselves

They seemed to be{r} screams of some person (or persons) in great agony — were loud and drawn out, not short and quick. Witness led the way up stairs. Upon reaching the first landing, heard two voices in loud and angry contention — the one a gruff voice, the other much shriller — a very strange voice. Could distinguish some words of the former, which was that of a Frenchman. Was positive that it was not a woman's voice. Could distinguish the words ‘sacré’{s} and ‘diable.’ The shrill voice was that of a foreigner. Could not be sure whether it was the voice of a man or of a woman.

Poe wrote his story hastily. The manuscript shows more changes than do most of his surviving manuscripts, which appear to be copies carefully made for the printer rather than working drafts.

Had the routine of our life at this place been known to the world, we should have been regarded as madmen — although, perhaps, as madmen of a harmless nature. Our seclusion was perfect. We admitted no visitors.{s} Indeed the locality of our retirement had been carefully kept a secret from my own former associates; and it had been many years since Dupin had ceased to know or be known in Paris. We existed within ourselves alone.

As the strong man exults in his physical ability, delighting in such exercises as call his muscles into action,(1) so glories the analyst in that moral activity which disentangles. He derives pleasure from even the most trivial occupations bringing his talent into play. He is fond of enigmas, of conundrums, of hieroglyphics; exhibiting in his solutions of each{b} a degree of acumen{c} which appears to the ordinary apprehension præternatural.

Voltaire's Zadig

An extraordinary burglary — attended by very singular circumstances, and perpetrated by a curious felon — occurred in this town on Monday night.

He is fond of enigmas, of conundrums, of hieroglyphics; exhibiting in his solutions of each{b} a degree of acumen{c} which appears to the ordinary apprehension præternatural.

It is the ancestor of a vast number of works which have given much harmless pleasure to all sorts and conditions of men.

shoved down our throats

themes of longing and loss and the close relationship between these two things, themes ofmeditation or philosophical contemplation, of political or moral outrage or celebration, praiseand blame, a concern with how difficult it can be to say just what we mean and feel we need tosay.

notbeing primarily concerned with telling a story at all,

Deep in the sun-searched growths the dragon-fly

And say you'd nearly brought me flowersBut something had gone wrong

Not for the proud man apartFrom the raging moon I writeOn these spindrift pagesNor for the towering deadWith their nightingales and psalms

craft or sullen ar

Tis visible silence, still as the hour-glass

Your eyes smile peace. The pasture gleams and glooms

Ask me no more

he golden atoms of the day;For in pure love heaven did prepar

poster boy for the Enlightenment.

“You will be expected to use AI generative tools in thisclass, following the instructor’s permissions and directions,”

She shows students how to engineerprompts so that AI can help them understand components of rhetoric,

Faculty members have begun using it tohelp them design their courses, viewing it as a tool that can make instructionmore effective and engaging.In his business-communication class, Carl Follmer, director of the FrankBusiness Communication Center in the University of Iowa’s Tippie College ofBusiness, created an AI chatbot he calls Impy.

The writing process also applies to timed writing tasks, such as essay exams.

Writing, on the other hand, gives you the chance to put down your ideas and make them stay put long enough for you to evaluate them

A user wants to comment on a single parameter name in a function. It is highlighted as a unique part of the syntax tree, and they're not happy with the particular name the author of the MR chose. Problem: The user can only comment on the entire line, because "lines" are considered the most fundamental building block in our Diffs UI.

an either one alone [45]. One year of briskwalking combined with gymnastic training either increasedor maintained the spine BMD in postmenopausal women[25]. Results from an earlier meta-analysis showed thatwalking with other AEXs significantly affected the BMD atspine, but not hip [46]. Bone mass increases or decreasesin response to mechanical loading depending on whetherthe thresholds controlling bone formation and resorptionhave been reached [47]. A few studies have demonstratedthe importance of walking intensity on

Globally, 70% of today’s urban growth (PDF) occurs outside the formal planning process.

Wikimedia is a global movement whose mission is to bring free educational content to the world.

let's assume that the price of oil uh is at least at the uh 75 range which keeps us out of trouble Keith is at least floating in Alberta maybe even 80 bucks 01:00:56 a barrel maybe even 85 so that we've got some extra money so uh we're going to appoint you and you get to look around for a female and uh 01:01:10 the two of you have to then look around for uh people who are uh indigenous male and female and the four of you are going to be a group and we're going to give you 01:01:22 um uh uh a hundred billion dollars to spend over 10 years which means that you've got uh 10 billion 100 million no we're going to do more 01:01:37 we're going to give you a billion dollars so you've got a hundred million a year and you're going to be able to give it away in 10 million dollar tranches

the Americanization of the culture of Alberta and the importance of American capital for the 00:24:23 energy industry but there was a lot of migration from the United States from Nebraska and Montana um up north yeah a third of the people who settled 00:24:35 the Prairies between 1880 and 1913 and a third of the three million who came were American my mother born in the U.S yes a lot of 00:24:48 the established you know people who've been here a while uh on the Canadian prairies we look South and we literally see cousins

A Method for Clustering Styles of Gamepl

This is the only way for an adult student to develop as an independent mind, a critical thinker, and a more educated human being.

The distinction doesn't refer to the files _contents_ but how to the file is _treated_ when it is being read or written. In "rb"/"wb" modes files are left how they are, in "r"/"w" modes Windows programmers get line ends "\r\n" translated into "\n" what disturbs file positions and string lengths.

Wikimedia is a global movement whose mission is to bring free educational content to the world.

that the load foran individual participant in an investigation isoften unreasonably large: to be ready for aninterview and in addition to provide a coun-selling conversation is, if measured against thenormal requirement of taking part in a study, acomparatively heavy burden.

how comparability of the samples

ecause of projectplanning and resources, the empirical steps haveto be conducted sequentially – first the observa-tional data are collected and analysed and thenthe interviews are conducted and analysed. Inthis case possible influences of the differenttimes on content should not be forgotten

This argument only works if what you’re defending is good. As I’ve already explained, SMS-2FA is not good.

We have a finite pool of good will with which we can advocate for the implementation of new security technologies. If we spend all that good will on irritating attackers, then by the time we’re ready to actually implement a solution, developers are not going to be interested.

That thou among the wastes of time must go,

With safety of her innocence;

This living hand, now warm and capable

Wij weten ook datdeze controles als enige middel slechts beperkt geschikt zijn arbeidsomstandighedente verbeteren of verborgen mensenrechten schendingen te ontdekken, bijv.mensenschendingen door dwangarbeid.

De implementatie van onze corporate due diligence aanpak is een dynamisch proces,waarvan wij de omvang en het ontwerp voortdurend controleren en verder ontwikkelenmet behulp van externe stakeholders en partners (bijv. maatschappelijke organisatiesen vakbonden).

Bij de aanpak van risico’s in onze toeleveringsketen op het gebied vanmensenrechten en milieu richten wij ons in de eerste plaats op de productie van onzeeigenmerken. Deze zijn niet alleen verantwoordelijk voor het grootste deel van onzeomzet. Wij zijn ook rechtstreeks voor onze eigenmerk producten verantwoordelijk. Ookbij de inkoop van merk producten verwachten we dat er rekening wordt gehouden met deimpact van het productieproces op mens en milieu.

we werken er continu aan om de kennis van onze inkopers op het gebiedvan sociale en ecologische kwesties te verbeteren. Via trainingen gericht op dezedoelgroep en gespecificeerd per productgroep, vergroten we de kennis van onzeinkopers en versterken we de centrale rol van duurzaamheid bij Lidl.

De beoordeling van mogelijke risico’s voor onze eigenmerk producten wordt uitgevoerddoor middel van een systematische procedure die is gebaseerd op indices zoals deGlobal Rights Index van de ITUC en de Global Slavery Index, en is gecombineerd metgegevens van de Verenigde Naties Voedsel- en Landbouworganisatie (FAO) en deEnvironmental Perfomance Index. Daarnaast gaan we continu in gesprek met externestakeholders en winnen de expertise in van bijvoorbeeld maatschappelijke organisaties,vakbonden en andere deskundigen. Samen met deze verschillende experts kunnen wein kaart brengen waar de grootste uitdagingen zijn om mensenrechten schendingen tevoorkomen en kunnen we maatregelen ontwikkelen om deze obstakels te verminderen,bijvoorbeeld obstakels in relatie tot vrijheid van vereniging of het recht op collectieveonderhandelingen

We erkennen tevens dat schendingen vanarbeidersrechten kunnen plaatsvinden omdat overheden niet in staat zijn deze adequaatte beschermen, of omdat werknemers zich niet in vrijheid en effectief kunnen verenigen.

It's a great way to test various limits. When you think about this even more, it's a little mind-bending, as we're trying to impose a global clock ("who is the most up to date") on a system that inherently doesn't have a global clock. When we scale time down to nanoseconds, this affects us in the real world of today: a light-nanosecond is not very far.

With the reading portion of the world it is generally known that I have devoted the greater partof my life in visiting, and recording the looks of, the various native Races of North and SouthAmerica; and during those researches, observing the healthy condition and physical perfection ofthose people, in their primitive state, as contrasted with the deplorable mortality, the numerousdiseases and deformities, in civilized communities, I have been led to search for, and able, Ibelieve, to discover, the main causes leading to such different results.

Preparing Your Mind for Innovation

Define table structure (columns and indexes) inside your ActiveRecord models like you can do in migrations. Also similar to DataMapper inline schema syntax.

Tabernacle

Statin exposure is associated with reduced development of acute on chronic liver failure in a veterans affairs cohort.

parents’ ruth,

you.

own heart dry of blood

now warm and capable

On the geopolitical stage, it’s hard to argue with the claim that Twitter is a force of evil. But Twitter is also the infrastructural backbone of much of the digital humanities world.

Tailwind automatically removes all unused CSS when building for production

x = -3 "++-"[x <=> 0] # => "-" x = 0 "++-"[x <=> 0] # => "+" x = 3 "++-"[x <=> 0] # => "+"

problem: low-resolution sourcemaps

One way to look at your current situation is that you're not paying them enough to tell you the gory details, not that you're not knowledgeable enough.

That image only contains 200 pixels horizontally, but the browser stretches it to 400px wide or even farther!Luckily, you’ll see there’s an easy “fix” there at the end: our old good friend the width attribute!<img src="example.gif", srcset="example.gif 200w" sizes="(min-width: 400px) 400px, 100vw" width="200" /* <=== TA-DA! */ class="logo">As long as you can specify the width attribute so it reflects the true maximum size of your largest image, you won’t run into this problem of having sizes make your image wider than it naturally should go.

We haven’t covered this yet, but HEY has another consent-based feature they call the Speakeasy code. When used in the subject line of an email, this code grants the email access straight to the Imbox.

that garbage has ZERO damned business in an e-mail which is why a great many places use HTML only e-mail as a trigger for spam detection! (if you send multipart as both text/html and text/plain, you're fine)