- Jul 2024
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www.epi.org www.epi.org
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The age cohort projected to make the earliest transition to majority-minority is the one that includes workers age 25 to 34. These are today’s 18- to 27-year-olds and for them, the projected transition year is 2021.
for - stats - 25 to 34 year old people of color is earliest U.S. working class cohort to transition in the year 2021.
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- Jan 2023
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hypothes.is hypothes.is
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Finally, a culture that rewards big personal accomplishments over smaller social ones threatens to create a cohort of narcissists
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- Nov 2022
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community.interledger.org community.interledger.org
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not really about the content of the sessions. Or anything you take from it. The most important thing are the relationships, the connections you gain from sharing the things you're passionate about with the people who are interested in it, the momentum you build from working on your project in preparation for a session
I somewhat disagree - I think this community building is successful precisely because there is a shared interest or goal. It goes hand in hand. If there is no connecting theme or goal, the groups fall apart.
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- May 2022
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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DICER1 syndrome encompasses a variety of benign and malignant manifestations including multinodular goitre
Gene: DICER1 PMCID: PMC8451242 PMID: 34552563 Pathogenic Inheritance Pattern: Autosomal Dominant MultipleDiseaseEntities Disease Entity: DICER1 syndrome, multinodular goitre, cystic nephroma, anaplastic renal sarcoma, Wilms tumour, differentiated thyroid carcinoma, gynandroblastoma, ciliary body medulloepithelioma, embryonal rhabdomyosarcoma, pineoblastoma, pituitary blastoma, kidney cyst, pulmonary cyst, Sertoli-Leydig Cell Tumor. Mutation: Germline MultipleGeneVariants Variant & Clinvar IDs: c.3452_3453del (485534), c.316del (no ClinVar ID), c.171_172insAC (no ClinVar ID), c.3434del (no ClinVar ID), c.988C>T (933007), c.5388dup (no ClinVar ID) Zygosity: None provided. Case: At time of operation, the goitre patients living in Denmark were ages 21, 12, 21, 8, 14, and 16. Four underwent total thyroidectomies, and two underwent partial thyroidectomies. The patient originally aged 21 previously had a kidney cyst at age 14 and a pulmonary cyst at an unknown age. The patient aged 14 at time of partial thyroidectomy later manifested a Sertoli-Leydig Cell Tumor at age 15. All six patients were female. CasePresentingHPO: None provided. CasePreviousTesting: thyroidectomy gnomAD: ENSG00000100697.10, https://gnomad.broadinstitute.org/gene/ENSG00000100697 Mutation Type: Frameshift, Nonsense
Tags
- Cohort
- MultipleGeneVariants
- c.171_172insAC
- c.316del
- thyroidectomy
- Germline
- female
- DICER1
- c.988C>T
- c.5388dup
- goiter
- cancer
- gnomAD:ENSG00000100697.10
- Age:8
- ClinvarID:NotProvided
- ClinvarID:485534
- Age:21
- Mutation:Nonsense
- ClinvarID:933007
- Age:12
- Mutation:Frameshift
- AutosomalDominant
- PMID:34552563
- Frameshift
- c.3452_3453del
- Gene:DICER1
- Pathogenic
- goitre
- MultipleDiseaseEntities
- c.3434del
- Nonsense
- Age:14
- PMCID:PMC8451242
Annotators
URL
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- Apr 2022
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twitter.com twitter.com
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(1) ReconfigBehSci on Twitter: ‘RT @ahandvanish: New paper on 10,024 breakthrough infections shows that vaccination does not prevent #LongCovid. Https://t.co/8WurrqXRwy…’ / Twitter. (n.d.). Retrieved 29 October 2021, from https://twitter.com/SciBeh/status/1453638123624226822
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- Feb 2022
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twitter.com twitter.com
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APPG on Coronavirus. (2022, January 18). 🗣Dr.Claire Steves continued: “Looking in the national core studies, from cohort studies across the UK we’ve looked at 10 different longitudinal studies. Our best estimates are that about 5% of middle aged people are experiencing long term.. 27/ #APPGCoronavirus #LongCovid [Tweet]. @AppgCoronavirus. https://twitter.com/AppgCoronavirus/status/1483453895061999618
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- Oct 2021
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www.thelancet.com www.thelancet.com
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Singanayagam, A., Hakki, S., Dunning, J., Madon, K. J., Crone, M. A., Koycheva, A., Derqui-Fernandez, N., Barnett, J. L., Whitfield, M. G., Varro, R., Charlett, A., Kundu, R., Fenn, J., Cutajar, J., Quinn, V., Conibear, E., Barclay, W., Freemont, P. S., Taylor, G. P., … Lackenby, A. (2021). Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: A prospective, longitudinal, cohort study. The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(21)00648-4
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www.thelancet.com www.thelancet.com
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Tartof, S. Y., Slezak, J. M., Fischer, H., Hong, V., Ackerson, B. K., Ranasinghe, O. N., Frankland, T. B., Ogun, O. A., Zamparo, J. M., Gray, S., Valluri, S. R., Pan, K., Angulo, F. J., Jodar, L., & McLaughlin, J. M. (2021). Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: A retrospective cohort study. The Lancet, 398(10309), 1407–1416. https://doi.org/10.1016/S0140-6736(21)02183-8
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www.thelancet.com www.thelancet.com
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Nordström, P., Ballin, M., & Nordström, A. (2021). Effectiveness of heterologous ChAdOx1 nCoV-19 and mRNA prime-boost vaccination against symptomatic Covid-19 infection in Sweden: A nationwide cohort study. The Lancet Regional Health – Europe, 0(0). https://doi.org/10.1016/j.lanepe.2021.100249
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jamanetwork.com jamanetwork.com
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Meuris, C., Kremer, C., Geerinck, A., Locquet, M., Bruyère, O., Defêche, J., Meex, C., Hayette, M.-P., Duchene, L., Dellot, P., Azarzar, S., Maréchal, N., Sauvage, A.-S., Frippiat, F., Giot, J.-B., Léonard, P., Fombellida, K., Moutschen, M., Durkin, K., … Darcis, G. (2021). Transmission of SARS-CoV-2 After COVID-19 Screening and Mitigation Measures for Primary School Children Attending School in Liège, Belgium. JAMA Network Open, 4(10), e2128757. https://doi.org/10.1001/jamanetworkopen.2021.28757
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- Sep 2021
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www.bmj.com www.bmj.com
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Hippisley-Cox, J., Coupland, C. A., Mehta, N., Keogh, R. H., Diaz-Ordaz, K., Khunti, K., Lyons, R. A., Kee, F., Sheikh, A., Rahman, S., Valabhji, J., Harrison, E. M., Sellen, P., Haq, N., Semple, M. G., Johnson, P. W. M., Hayward, A., & Nguyen-Van-Tam, J. S. (2021). Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: National prospective cohort study. BMJ, 374, n2244. https://doi.org/10.1136/bmj.n2244
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- Aug 2021
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twitter.com twitter.com
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Leif Erik Sander. “1/6 Our Study Comparing Reactogenicity & Immunogenicity of Homologous (2xBNT/Pfizer) vs Heterologous (AZ/ChAdOx +BNT) Vaccination Is Available Https://Medrxiv.Org/Content/10.1101/2021.05.19.21257334v2 Great Team Effort @vmcorman #FlorianKurth #DavidHillus #TatjanaSchwarz #PinkusToberLau et al. @ChariteBerlin 🧵 Https://T.Co/4zXfY4rV9c.” Tweet. @Sander_Lab (blog), June 2, 2021. https://twitter.com/Sander_Lab/status/1400178343123853321.
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- Jul 2021
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www.sciencedirect.com www.sciencedirect.com
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Regev-Yochay, G., Amit, S., Bergwerk, M., Lipsitch, M., Leshem, E., Kahn, R., Lustig, Y., Cohen, C., Doolman, R., Ziv, A., Novikov, I., Rubin, C., Gimpelevich, I., Huppert, A., Rahav, G., Afek, A., & Kreiss, Y. (2021). Decreased infectivity following BNT162b2 vaccination: A prospective cohort study in Israel. The Lancet Regional Health - Europe, 7, 100150. https://doi.org/10.1016/j.lanepe.2021.100150
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- Jun 2021
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www.bmj.com www.bmj.com
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Li, X., Ostropolets, A., Makadia, R., Shoaibi, A., Rao, G., Sena, A. G., Martinez-Hernandez, E., Delmestri, A., Verhamme, K., Rijnbeek, P. R., Duarte-Salles, T., Suchard, M. A., Ryan, P. B., Hripcsak, G., & Prieto-Alhambra, D. (2021). Characterising the background incidence rates of adverse events of special interest for covid-19 vaccines in eight countries: Multinational network cohort study. BMJ, 373, n1435. https://doi.org/10.1136/bmj.n1435
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www.nature.com www.nature.com
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Pishko, A. M., Bussel, J. B., & Cines, D. B. (2021). COVID-19 vaccination and immune thrombocytopenia. Nature Medicine, 1–2. https://doi.org/10.1038/s41591-021-01419-1
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jamanetwork-com.ezproxy.lib.ucalgary.ca jamanetwork-com.ezproxy.lib.ucalgary.ca
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Daniels, Curt J., Saurabh Rajpal, Joel T. Greenshields, Geoffrey L. Rosenthal, Eugene H. Chung, Michael Terrin, Jean Jeudy, et al. “Prevalence of Clinical and Subclinical Myocarditis in Competitive Athletes With Recent SARS-CoV-2 Infection: Results From the Big Ten COVID-19 Cardiac Registry.” JAMA Cardiology, May 27, 2021. https://doi.org/10.1001/jamacardio.2021.2065.
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- Apr 2021
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careerfoundry.com careerfoundry.com
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While there are certain things most users will anticipate with any interface, there may be expected affordances that are unique to your users and the cohort they represent
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- Mar 2021
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pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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Gray, Kathryn J., Evan A. Bordt, Caroline Atyeo, Elizabeth Deriso, Babatunde Akinwunmi, Nicola Young, Aranxta Medina Baez, et al. ‘COVID-19 Vaccine Response in Pregnant and Lactating Women: A Cohort Study’. MedRxiv: The Preprint Server for Health Sciences, 8 March 2021. https://doi.org/10.1101/2021.03.07.21253094.
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www.bmj.com www.bmj.com
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Clift, Ash K., Carol A. C. Coupland, Ruth H. Keogh, Karla Diaz-Ordaz, Elizabeth Williamson, Ewen M. Harrison, Andrew Hayward, et al. ‘Living Risk Prediction Algorithm (QCOVID) for Risk of Hospital Admission and Mortality from Coronavirus 19 in Adults: National Derivation and Validation Cohort Study’. BMJ 371 (20 October 2020): m3731. https://doi.org/10.1136/bmj.m3731.
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- Jan 2021
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www.medrxiv.org www.medrxiv.org
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MacKenna, Brian, Helen J. Curtis, Caroline E. Morton, Peter Inglesby, Alex J. Walker, Jessica Morley, Amir Mehrkar, u. a. „Trends, Regional Variation, and Clinical Characteristics of COVID-19 Vaccine Recipients: A Retrospective Cohort Study in 23.4 Million Patients Using OpenSAFELY.“ MedRxiv, 26. Januar 2021, 2021.01.25.21250356. https://doi.org/10.1101/2021.01.25.21250356.
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- Sep 2020
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www.thelancet.com www.thelancet.com
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Williams, R., Jenkins, D. A., Ashcroft, D. M., Brown, B., Campbell, S., Carr, M. J., Cheraghi-sohi, S., Kapur, N., Thomas, O., Webb, R. T., & Peek, N. (2020). Diagnosis of physical and mental health conditions in primary care during the COVID-19 pandemic: A retrospective cohort study. The Lancet Public Health, 0(0). https://doi.org/10.1016/S2468-2667(20)30201-2
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- Aug 2020
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jamanetwork.com jamanetwork.com
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Yang, B. Y., Barnard, L. M., Emert, J. M., Drucker, C., Schwarcz, L., Counts, C. R., Murphy, D. L., Guan, S., Kume, K., Rodriquez, K., Jacinto, T., May, S., Sayre, M. R., & Rea, T. (2020). Clinical Characteristics of Patients With Coronavirus Disease 2019 (COVID-19) Receiving Emergency Medical Services in King County, Washington. JAMA Network Open, 3(7), e2014549–e2014549. https://doi.org/10.1001/jamanetworkopen.2020.14549
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Nguyen, L. H., Drew, D. A., Graham, M. S., Joshi, A. D., Guo, C.-G., Ma, W., Mehta, R. S., Warner, E. T., Sikavi, D. R., Lo, C.-H., Kwon, S., Song, M., Mucci, L. A., Stampfer, M. J., Willett, W. C., Eliassen, A. H., Hart, J. E., Chavarro, J. E., Rich-Edwards, J. W., … Zhang, F. (2020). Risk of COVID-19 among front-line health-care workers and the general community: A prospective cohort study. The Lancet Public Health, 0(0). https://doi.org/10.1016/S2468-2667(20)30164-X
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www.sciencedirect.com www.sciencedirect.com
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Xu, G., Qi, F., Li, H., Yang, Q., Wang, H., Wang, X., Liu, X., Zhao, J., Liao, X., Liu, Y., Amit, I., Liu, L., Zhang, S., & Zhang, Z. (2020). The differential immune responses to COVID-19 in peripheral and lung revealed by single-cell RNA sequencing. MedRxiv, 2020.08.15.20175638. https://doi.org/10.1101/2020.08.15.20175638
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academic.oup.com academic.oup.com
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Yan, Q., Zuo, P., Cheng, L., Li, Y., Song, K., Chen, Y., Dai, Y., Yang, Y., Zhou, L., Yu, W., Li, Y., Xie, M., Zhang, C., & Gao, H. (n.d.). Acute Kidney Injury Is Associated With In-hospital Mortality in Older Patients With COVID-19. The Journals of Gerontology: Series A. https://doi.org/10.1093/gerona/glaa181
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Salvatore, C. M., Han, J.-Y., Acker, K. P., Tiwari, P., Jin, J., Brandler, M., Cangemi, C., Gordon, L., Parow, A., DiPace, J., & DeLaMora, P. (2020). Neonatal management and outcomes during the COVID-19 pandemic: An observation cohort study. The Lancet Child & Adolescent Health, 0(0). https://doi.org/10.1016/S2352-4642(20)30235-2
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- Jul 2020
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osf.io osf.io
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Nivette, A., Ribeaud, D., Murray, A. L., Steinhoff, A., Bechtiger, L., Hepp, U., Shanahan, L., & Eisner, M. (2020). Non-compliance with COVID-19-related public health measures among young adults: Insights from a longitudinal cohort study [Preprint]. SocArXiv. https://doi.org/10.31235/osf.io/8edbj
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jamanetwork.com jamanetwork.com
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Weinberger, D. M., Chen, J., Cohen, T., Crawford, F. W., Mostashari, F., Olson, D., Pitzer, V. E., Reich, N. G., Russi, M., Simonsen, L., Watkins, A., & Viboud, C. (2020). Estimation of Excess Deaths Associated With the COVID-19 Pandemic in the United States, March to May 2020. JAMA Internal Medicine. https://doi.org/10.1001/jamainternmed.2020.3391
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medrxiv.org medrxiv.org
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Fontanet, A., Grant, R., Tondeur, L., Madec, Y., Grzelak, L., Cailleau, I., Ungeheuer, M.-N., Renaudat, C., Pellerin, S. F., Kuhmel, L., Staropoli, I., Anna, F., Charneau, P., Demeret, C., Bruel, T., Schwartz, O., & Hoen, B. (2020). SARS-CoV-2 infection in primary schools in northern France: A retrospective cohort study in an area of high transmission. MedRxiv, 2020.06.25.20140178. https://doi.org/10.1101/2020.06.25.20140178
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- Jul 2019
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www.tonybates.ca www.tonybates.ca
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Communities of practice are one of the ways in which experiential learning, social constructivism, and connectivism can be combined, illustrating the limitations of trying to rigidly classify learning theories. Practice tends to be more complex.
Constructivism - roots in the philosophical and psychological viewpoints of this century, specially Piaget, Bruner and Goodman. Learning occurs when the mind filters inputs from the world to produce its unique reality. The mind is believed to be the source of all meaning, direct experiences with the environment are considered critical. It crosses both categories by emphasizing the interaction between learner and the real world.
Social constructivism would emphasize critical experiences between the learner and other learners and mentors.
Connectivism is the integration of principles explored by chaos, network, complexity and self-organization theory. A lot of the content is now offloaded to the machine that was previously residing within the learner.
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onlinelearninginsights.wordpress.com onlinelearninginsights.wordpress.com
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Connectivism is the theory behind massive open online courses, MOOCs
the author doesn't really elaborate as to how or why connectivism is the guiding theory behind moocs.
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