- May 2023
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institute
to originate and get established 建立
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Gold give us, God forgive us,And from all woes relieve us;That we the treasureMay reap of pleasure,And shun whate’er is grievous,Gold give us, God forgive us.
Why did he asked for god's forgiveness? Does that mean that he admits his request are greedy and not inclusive?
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Abbot
a man who is the head of an abbey of monks. 男修道院長
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mutual
Having the same feelings one for the other. 共同的、相互的。
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open.spotify.com open.spotify.com
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Schubert Symphony No 3 II
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micro.blog micro.blog
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For $1,900.00 ?
reply to rogerscrafford at tk
Fine furniture comes at a fine price. 🗃️🤩 I suspect that it won't sell for quite a while and one could potentially make an offer at a fraction of that to take it off their hands. It might bear considering that if one had a practice large enough to fill half or more, then that price probably wouldn't seem too steep for the long term security and value of the contents.
On a price per card of storage for some of the cheaper cardboard or metal boxes you're going to pay about $0.02-0.03 per card, but you'd need about 14 of those to equal this and those aren't always easy to stack and access regularly. With this, even at the full $1,900, you're looking at storage costs of $0.10/card, but you've got a lot more ease of use which will save you a lot of time and headache as more than adequate compensation, particularly if you're regularly using the approximately 20,400 index cards it would hold. Not everyone has the same esthetic, but I suspect that most would find that this will look a lot nicer in your office than 14 cheap cardboard boxes. That many index cards even at discount rates are going to cost you about $825 just in cards much less beautiful, convenient, and highly usable storage.
Even for some of the more prolific zettelkasten users, this sort of storage is about 20 years of use and if you compare it with $96/year for Notion or $130/year for Evernote, you're probably on par for cost either way, but at least with the wooden option, you don't have to worry about your note storage provider going out of business a few years down the line. Even if you go the "free" Obsidian route, with computers/storage/backups over time, you're probably not going to come out ahead in the long run. It's not all apples to apples comparison and there are differences in some of the affordances, but on balance and put into some perspective, it's probably not the steep investment it may seem.
And as an added bonus, while you're slowly filling up drawers, as a writer you might appreciate the slowly decreasing wine/whiskey bottle storage over time? A 5 x 8 drawer ought to fit three bottles of wine or as many fifths of Scotch. It'll definitely accommodate a couple of magnums of Jack Daniels. 🥃🍸🍷My experience also tells me that an old fashioned glass can make a convenient following block in card index boxes.
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- Apr 2023
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aught
anything 任何話
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yonder
something that is or is in an indicated more or less distant place 旁邊
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zounds
used as a mild oath 誓言
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eath
easy 簡單
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noddle,
head, pate 點頭
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hindrance
the act of interfering with or slowing the progress of someone or something : the action of hindering 阻礙、阻力
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prating
to talk long and idly 啐唸、喋喋不休
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friar,
a member of a mendicant order 修士
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abode
a temporary stay 暫住
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multitude
the state of being many 多數
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lest
for fear that 免得
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amicable
characterized by friendly goodwill 友好的
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eke
also 也
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avowed
openly acknowledged or declared 宣達、宣布
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dainty
something delicious to the taste 可口的
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thence
from that fact or circumstance 因此
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fillies
a young female horse usually of less than four years 年輕母馬 ; a young girl 女孩
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whence
from what place, source, or cause 何處
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comrades
an intimate friend or associate 同伴們、同志們
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confections
something confected 醋漬物
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fortify
to make strong 強化
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cavalier
a gentleman trained in arms and horsemanship 騎士
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behoved
chiefly British spelling of BEHOOVE: to be necessary, proper, or advantageous for 理應、應該、必須
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exultation
the act of exulting : the state of being exultant: filled with or expressing great joy or triumph 狂喜
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requital
something given in return, compensation, or retaliation 回禮、還禮
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consolation
the act or an instance of consoling, the state of being consoled 安慰
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whilst
while 當
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sagely
in a sage or wise manner 有禮的、明智的
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limned
to outline in clear sharp detail 被描繪輪廓的
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groat
hulled grain broken into fragments larger than grits 碎穀物、燕麥
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blest
to hallow or consecrate by religious rite or word 祝福
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hither;
being on the near or adjacent side 在附近、靠近
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guise
a form or style of dress 裝扮成
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delectation
Pleasure, delight, and enjoyment 快樂、喜悅
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avai
to be of use or advantage 有用、能用
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hath
archaic present tense third-person singular of HAVE 有著、懷抱著
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sendeth
the person to whom something is sent 發送、收件人
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irketh
furious, angry 憤怒
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affright
frighten, alarm 驚嚇、使恐懼
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bade
past tense and past participle of BID: to issue an order to 命令
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mar
to ruin or diminish the perfection or wholeness of 掃興、毀壞
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gospel
something accepted or promoted as infallible truth or as a guiding principle or doctrine 真理
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scant
barely or scarcely sufficient 不足
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you fort
adj. free from ambiguity or evasiveness : going straight to the point
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shalt
archaic present tense second-person singular of shall 將
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woeful
full of woe : grievous 可悲的、多災多難的
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bout
a spell or period of activity 一回合、一段時間
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, leaving h
adj. cheerless, dejected, downcast
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mayst
archaic present tense second-person singular of MAY 可能
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celestial
As in heavenly: of, relating to, or suggesting heaven 天堂的
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suffering
n. the state of being interfered with, held back, or slowed down : the state of being hindered
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disparage
As in to dismiss: to express scornfully one's low opinion of 貶損、批評
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e, studi
Adj. assiduous in the pursuit of learning
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drubbing
As in whipping: to defeat by a large margin 以很大差距輸掉(動詞); As in defeat: failure to win a contest 輸掉(名詞)
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h a tran
n. The act of exulting : the state of being exultant
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cudge
As in cane: a heavy rigid stick used as a weapon or for punishment 棍棒/長杖
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stout
As in sturdy: able to withstand hardship, strain, or exposure 穩固的 ; As in stocky: being compact and broad in build and often short in stature 粗壯的 ; As in valiant: feeling or displaying no fear by temperament 勇敢的 ; As in solid: not showing weakness or uncertainty 堅定的、堅固的、堅強的
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ere
As in before: earlier than 在...之前
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orisons
As in prayers: an address to God or a deity 禱告(名詞)
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chastised
to inflict a penalty on for a fault or crime 懲罰、懲戒、責罵
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bespoke
to make known (something abstract) through outward signs 展示/顯示
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whenas
when當
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en.wikipedia.org en.wikipedia.org
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Catalog cards were 2 by 5 inches (5 cm × 13 cm); the Harvard College size.
Early library card catalogs used cards that were 2 x 5" cards, the Harvard College size, before the standardization of 3 x 5" index cards.
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www.youtube.com www.youtube.com
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archive.org archive.org
- Mar 2023
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www.frontiersin.org www.frontiersin.org
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we propose five cornerstones that help deal with the highlighted issues and categorize unintended consequences.
5 principles for mitigating progress traps - 1) - a priori assessments of potential unintended consequences of policies - should be conducted by - multidisciplinary teams - with as broad a range of expertise as possible. - This would require decision-making - to flex around specific policy challenges - to ensure that decision-makers reflect the problem space in question. - 2) - policy plans made in light of the assessment should be iterative, - with scheduled re-assessments in the future. - As has been discussed above, - knowledge and circumstances change. - New consequences might have since - become manifest or new knowledge developed. - By planning and implementing reviews, - organizational reflexivity and - humility - needs to be built into decision-making systems (e.g., Treasury, 2020).
- 3)
- given the scale of systems
- such as the water-energy-food nexus
- and the potential for infinite variety and nuance of unintended consequences,
- pragmatism necessitates specification of boundaries
- within which assessments are made.
- pragmatism necessitates specification of boundaries
- It should be noted that this can in itself give rise to unintended consequences
- through potential omission of relevant areas.
- Hence, boundary decisions regarding
- where the boundaries lie
- should be regularly revisited (as per 2) above.
- where the boundaries lie
- given the scale of systems
- 4)
- unintended consequences identified
- should be placed in the framework
- with as much consensus among decision-makers as possible.
- should be placed in the framework
- The positioning does not need to be limited to a single point,
- but could be of the form of a distribution of opinions of range
- of knowability and
- avoidability;
- the distribution will be indicative of
- the perspectives and
- opinions of the stakeholders.
- but could be of the form of a distribution of opinions of range
- If a lack of consensus exists on the exact position,
- this can highlight a need to
- seek more diverse expertise, or
- for further research in order to improve consensus, or
- for fragmenting of the issue into
- smaller,
- more readily assessable pieces.
- this can highlight a need to
- unintended consequences identified
- 5)
- there is a need for more active learning
- by decision-makers
- about how to avoid repeating past unintended consequences.
- by decision-makers
- To support this,
- assessment process and
- outcomes should be
- documented and
- used
- to appraise the effectiveness of policy mechanisms,
- with specific attention on outcomes
- beyond those defined by policy objectives and the
- assumptions and
- decisions
- which led to these outcomes.
- beyond those defined by policy objectives and the
- with specific attention on outcomes
- Such appraisals could reflect on
- the scope of the assessment, and
- the effectiveness of specific groups of stakeholders
- in being able to identify potential negative outcomes,
- highlighting gaps in knowledge and limitations in the overall approach.
- in being able to identify potential negative outcomes,
- Additional records of the level of agreement of participants
- would allow for re-evaluation with new learning.
- there is a need for more active learning
- 3)
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it is for the parents to guide them frominfancy in the ways of virtue, propriety, and worthy Christian conduct, so that when grown up they may be thestaff of their parents’ old age, and the glory of their posterity; and to force them to study this or that science I donot think wise, though it may be no harm to persuade them; and when there is no need to study for the sake ofpane lucrando, and it is the student’s good fortune that heaven has given him parents who provide him with it, itwould be my advice to them to let him pursue whatever science they may see him most inclined to
This may be the best way to teach children, nowadays.
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I, Senor Don Quixote,” answered the gentleman, “have one son, without whom, perhaps, I should count myselfhappier than I am, not because he is a bad son, but because he is not so good as I could wish. He is eighteen yearsof age; he has been for six at Salamanca studying Latin and Greek, and when I wished him to turn to the study ofother sciences I found him so wrapped up in that of poetry (if that can be called a science) that there is no gettinghim to take kindly to the law, which I wished him to study, or to theology, the queen of them all. I would like him tobe an honour to his family, as we live in days when our kings liberally reward learning that is virtuous and worthy;for learning without virtue is a pearl on a dunghill. He spends the whole day in settling whether Homer expressedhimself correctly or not in such and such a line of the Iliad, whether Martial was indecent or not in such and suchan epigram, whether such and such lines of Virgil are to be understood in this way or in that; in short, all his talkis of the works of these poets, and those of Horace, Perseus, Juvenal, and Tibullus; for of the moderns in our ownlanguage he makes no great account; but with all his seeming indifference to Spanish poetry, just now his thoughtsare absorbed in making a gloss on four lines that have been sent him from Salamanca, which I suspect are for somepoetical tournament.”
I think Don Quixote thinks this is not why we study poetry.
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squire
in the past in England, a man who owned most of the land around a village (舊時英格蘭的)鄉紳,大地主
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enmity
a feeling of hate仇恨,怨恨;敵意
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Don Quixote turned to look and found that it was true, and rejoicing exceedingly, he concluded that they weretwo armies about to engage and encounter in the midst of that broad plain;
His bravery is his biggest trait.
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sonorous
having a deep, pleasant sound (聲音)渾厚的
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it was not right thata horse belonging to a knight so famous, and one with such merits of his own, should be without some distinctivename
The question of identity is always intriguing.
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ed away by theintense enjoyment he found in these pleasant fancies, he sethimself forthwith to put his scheme into execution
This is what I like about Don Quixote. He think of what he wants to do first and execute it, instead of what he can do, because I know that if I only think of what I can do in the beginning, then I will achieve nothing.
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In short, his wits being quite gone, he hit upon the strang-est notion that ever madman in this world hit upon, and thatwas that he fancied it was right and requisite, as well for thesupport of his own honour as for the service of his country,that he should make a knight-errant of himself,
Mostly, ambition is perceived as mad, but being mad is not always a bad thing.
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curate
a priest of the lowest rank, especially in the Church of England, whose job is to help the vicar (= priest of a particular area) (尤指英國國教會的)助理牧師
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mutton
the meat from a goat or sheep eaten as food 羊肉,山羊肉
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convent
a building in which nuns (= members of a female religious order) live 女修道院
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thereupon
immediately after something that is mentioned 隨即,立即
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For how shall I be able, said he, to rule over others, that havenot full power and command of myself?
Many leader lead other very well, but lose control of their own life.
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hereafter
starting from this time; in the future 此後,今後
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peremptory
expecting to be obeyed immediately and without asking questions 不容置辯的;專橫的,霸道的
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abstinence
not doing something, such as drinking alcohol or having sex 節制;戒絕
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meek
quiet, gentle, and not willing to argue or express your opinions in a forceful way 溫順的;謙和的
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solicit
to ask someone for money, information, or help 請求,索求,乞求
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countenance
the appearance or expression of someone's face面容;臉色;面部表情
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enamoured
liking something a lot 喜愛的;迷戀的
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www.shopbrodart.com www.shopbrodart.com
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Brodart Full-Length Single Charging Tray<br /> Full- length charging tray with 1,000-card capacity<br /> Price: $96.32
- Adjustable steel follower block with automatic lock
- Felt pads on tray bottom protect desktop
- Full-length charging tray for countertop use
- 4"H x 4"W x 16"D
- Holds 1,000 5"H x 3"W cards
- Includes antimicrobial finish
- Made in the USA
See also: https://hypothes.is/a/ao89RMQmEe2zIvsu3lf6kw for a smaller version
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www.shopbrodart.com www.shopbrodart.com
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Brodart Mini Single Charging Tray Mini single charging tray with 600-card capacity More Info Price: $76.76
- Adjustable steel follower block with automatic lock
- Felt pads on tray bottom protect desktop
- Mini charging tray fits on your lap
- 4"H x 4"W x 8"D
- Holds 600 5"H x 3"W cards
- Includes antimicrobial finish
- Made in the USA
This could be used for a modern day Memindex box for portrait oriented 3 x 5" index cards.
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books.googleusercontent.com books.googleusercontent.comcontent1
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2 3-4 x 4 3-4 inches in size, made of seal grain , real sealor Russia leather, in a thoro
Memindex dimensions mentioned in a 1904 advertisement<br /> cards: 2 3/4 x 4 1/2 inches<br /> case: 2 3/4 x 4 3/4 inches
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www.ebay.com www.ebay.com
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1930s Wilson Memindex Co Index Card Organizer Pre Rolodex Ad Price List Brochure
archived page: https://web.archive.org/web/20230310010450/https://www.ebay.com/itm/165910049390
Includes price lists
List of cards includes: - Dated tab cards for a year from any desired. - Blank tab cards for jottings arranged by subject. - These were sold in 1/2 or 1/3 cut formats - Pocket Alphabets for jottings arranged by letter. - Cash Account Cards [without tabs]. - Extra Record Cards for permanent memoranda. - Monthly Guides for quick reference to future dates. - Blank Guides for filing records by subject.. - Alphabet Guides for filing alphabetically.
Memindex sales brochures recommended the 3 x 5" cards (which had apparently been standardized by 1930 compared to the 5 1/2" width from earlier versions around 1906) because they could be used with other 3 x 5" index card systems.
In the 1930s Wilson Memindex Company sold more of their vest pocket sized 2 1/4 x 4 1/2" systems than 3 x 5" systems.
Some of the difference between the vest sized and regular sized systems choice was based on the size of the particular user's handwriting. It was recommended that those with larger handwriting use the larger cards.
By the 1930's at least the Memindex tag line "An Automatic Memory" was being used, which also gave an indication of the ubiquity of automatization of industrialized life.
The Memindex has proved its success in more than one hundred kinds of business. Highly recommended by men in executive positions, merchants, manufacturers, managers, .... etc.
Notice the gendering of users specifically as men here.
Features: - Sunday cards were sold separately and by my reading were full length tabs rather than 1/6 tabs like the other six days of the week - Lids were custom fit to the bases and needed to be ordered together - The Memindex Jr. held 400 cards versus the larger 9 inch standard trays which had space for 800 cards and block (presumably a block to hold them up or at an angle when partially empty).
The Memindex Jr., according to a price sheet in the 1930s, was used "extensively as an advertising gift".
The Memindex system had cards available in bundles of 100 that were labeled with the heading "Things to Keep in Sight".
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312 Oak Midget Tray WWeesCoverEquipped same as]No.324,price.55CTohold cards14x3.No.423.Equippedasabove,tohold65Ccards 24x4, priceNo. 533. Standard size.to hold card 3x5, equip-ped as above,price..........No. 7- Nickel ....PrepaidinU. S.onreceiptofpriceNo. 324OakMidgetTraytheCoverWeis75cNo. 644. To hold cards4x6,equipped$1.10(StyleNos.312,423.533and644)asabove......(Style No. 324,213.335and446.)Send for catalog showing many other time-saving office devices. Our goods are soldyour dealer does not carry our line we can supply you direct from the factory.To hold cards 24x4. lengthof tray2%in..equippedwithAtoZindexand100record cards 45cNo. 213. To hold cards 14x3in,, lenght of tray 24in..equipped asabove40cNo.335.Standardsize,tohold3x5 cards.equipped asabove50c80cNo. 446. To hold 4x6 cards,equipped asabove.Any of these trays sent pre-paid in U. S. on receipt ofpriceby stationers everywhere. IfNo. 6 Union St.The WeisManufacturing Co.,Monroe,Mich.,U. S.A.Please mention SYSTEM when writing to advertisers
Notice the 1 1/4" x 3" cards, 2 1/4 x 4" cards in addition to the 3 x 5" and 4 x 6".
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www.defenseurdesdroits.fr www.defenseurdesdroits.fr
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RECOMMANDATION N°8La Défenseure des droits recommandeau ministre des Solidarités, de l’Autonomieet des Personnes handicapées et à la ministredéléguée chargée des Personneshandicapées :• De rappeler aux MDPH d’adopter un PPSafin, conformément à l’article D. 351-5 ducode de l’éducation, de définir et coordonnerles modalités de déroulement de la scolaritéet les actions pédagogiques, psychologiques,éducatives, sociales, médicales etparamédicales répondant aux besoinsparticuliers des élèves présentant unhandicap ;• D’inviter les CDPAH à préciser, dansleurs décisions, les activités à réaliserpar les AESH affectés auprès des enfants
Recommandation 08
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- Feb 2023
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knowligence.info knowligence.info
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Considering the above120 and in light of the specific circumstances of the processing, the EDPB finds that the IE SA could not have concluded in paragraph 115 of the Draft Decision that the contact information processing may be regarded as necessary for the performance of a contract between Meta IE and child users.
Holding. Not necessary.
"As a consequence, the EDPB finds that Meta IE could not have relied on [[Article 6(1)(b)]] GDPR as a legal basis for the contact information processing.”
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As noted by the IE SA, the HTML publication of contact information was not considered necessary by Facebook’s Security Team and was subsequently discontinued117. The EDPB considers that the analysis of the principle of data minimisation (Article 5(1)(c) GDPR) is relevant for the necessity assessment on the basis of Article 6(1)(b) GDPR118. Consequently, the EDPB further finds that such analysis should have complemented the LSA’s assessment on the necessity of the processing for the performance of the contract, with specific regard to the publication of the contact information in the HTML source code on the Instagram website. The EDPB considers that the IE SA could not have concluded that the publication of the contact information of child users in the HTML source code may be regarded as
EDPB rightly smacks the IE SA around a bit for generally cocking this all up.
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cppa.ca.gov cppa.ca.gov
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shall be reasonably necessary and proportionate to achieve the purpose(s) for which thepersonal information was collected or processed
Reasonable & proportionality. Set to expectations of what a consumer would expect of use.
Cannot be used for other disclosed purposes if they are compatible with what's reasonably expected. This is Article 5 lite.
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hypothes.is hypothes.is
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Conversation Hey, JB, I played a pickup game at the Rec today. At first, the older guys laughed and wouldn’t let me in unless I could hit from half-court . . . Of course, I did. All net. I wait for JB to say something, but he just smiles, his eyes all moony. I showed them guys how the Bells ball. I scored fourteen points. They told me I should try out for junior varsity next year ’cause I got hops . . . JB, are you listening? JB nods, his fingers tapping away on the computer, chatting probably with Miss Sweet Tea. I told the big guys about you, too. They said we could come back and run with them anytime. What do you think about that? HELLO—Earth to JB? Even though I know he hears me, the only thing JB is listening to is the sound of his heart bouncing on the court of love.
Conversation Dad, this girl is making Jordan act weird. He’s here, but he’s not. He’s always smiling. His eyes get all spacey whenever she’s around, and sometimes when she’s not. He wears your cologne. He’s always texting her. He even wore loafers to school. Dad, you gotta do something. Dad does something. He laughs. Filthy, talking to your brother right now would be like pushing water uphill with a rake, son. This isn’t funny, Dad. Say something to him. Please. Filthy, if some girl done locked up JB, he’s going to jail. Now let’s go get some doughnuts.
Basketball Rule #5 When you stop playing your game you’ve already lost.
Showoff UP by sixteen with six seconds showing, JB smiles, then STRUTS side steps stutters Spins, and SI NKS a sick SLICK SLIDING SWeeeeeeeeeeT SEVEN-foot shot. What a showoff.
Out of Control Are you kidding me? Come on. Ref, open your eyes. Ray Charles could have seen that kid walked. CALL THE TRAVELING VIOLATION! You guys are TERRIBLE! Mom wasn’t at the game tonight, which meant that all night Dad was free to yell at the officials, which he did.
Mom calls me into the kitchen after we get home from beating St. Francis. Normally she wants me to sample the macaroni and cheese to make sure it’s cheesy enough, or the oven-baked fried chicken to make sure it’s not greasy and stuff, but today on the table is some gross-looking orange creamy dip with brown specks in it. A tray of pita-bread triangles is beside it. Maybe Mom is having one of her book club meetings. Sit down, she says. I sit as far away from the dip as possible. Maybe the chicken is in the oven. Where is your brother? she asks. Probably on the phone with that girl. She hands me a pita. No thanks, I say, then stand up to leave, but she gives me a look that tells me she’s not finished with me. Maybe the mac is in the oven. We’ve talked to you two about your grandfather, she says. He was a good man. I’m sorry you never got to meet him, Josh. Me too, he looked cool in his uniforms. That man was way past cool. Dad said he used to curse a lot and talk about the war. Mom’s laugh is short, then she’s serious again. I know we told you Grandpop died after a fall, but the truth is he fell because he had a stroke. He had a heart disease. Too many years of bad eating and not taking care of himself and so— What does this have to do with anything? I ask, even though I think I already know. Well, our family has a history of heart problems, she says, so we’re going to start eating better. Especially Dad. And we’re going to start tonight with some hummus and pita bread. FOR MY VICTORY DINNER? Josh, we’re going to try to lay off the fried foods and Golden Dragon. And when your dad takes you to the recreation center, no Pollard’s or Krispy Kreme afterward, understand? And I understand more than she thinks I do. But is hummus really the answer?
35–18 is the final score of game six. A local reporter asks JB and I how we got so good. Dad screams from behind us, They learned from Da Man! The crowd of parents and students behind us laughs. On the way home Dad asks if we should stop at Pollard’s. I tell him I’m not hungry, plus I have a lot of homework, even though I skipped lunch today and finished my homework during halftime.
Too Good Lately, I’ve been feeling like everything in my life is going right: I beat JB in Madden. Our team is undefeated. I scored an A+ on the vocabulary test. Plus, Mom’s away at a conference, which means so is the Assistant Principal. I am a little worried, though, because, as Coach likes to say, you can get used to things going well, but you’re never prepared for something going wrong.
I’m on Free Throw Number Twenty-Seven We take turns, switching every time we miss. JB has hit forty-one, the last twelve in a row. Filthy, keep up, man, keep up, he says. Dad laughs loud, and says, Filthy, your brother is putting on a free-throw clinic. You better— And suddenly he bowls over, a look of horror on his face, and starts coughing while clutching his chest, only no sound comes. I freeze. JB runs over to him. Dad, you okay? he asks. I still can’t move. There is a stream of sweat on Dad’s face. Maybe he’s overheating, I say. His mouth is curled up like a little tunnel. JB grabs the water hose, turns the faucet on full blast, and sprays Dad. Some of it goes in Dad’s mouth. Then I hear the sound of coughing, and Dad is no longer leaning against the car, now he’s moving toward the hose, and laughing. So is JB. Then Dad grabs the hose and sprays both of us. Now I’m laughing too, but only on the outside.
He probably just got something stuck in his throat, JB says when I ask him if he thought Dad was sick and shouldn’t we tell Mom what happened. So, when the phone rings, it’s ironic that after saying hello, he throws the phone to me, because, even though his lips are moving, JB is speechless, like he’s got something stuck in his throat.
i·ron·ic [AY-RON-IK] adjective Having a curious or humorous unexpected sequence of events marked by coincidence. As in: The fact that Vondie hates astronomy and his mom works for NASA is ironic. As in: It’s not ironic that Grandpop died in a hospital and Dad doesn’t like doctors. As in: Isn’t it ironic that showoff JB, with all his swagger, is too shy to talk to Miss Sweet Tea, so he gives me the phone?
This Is Alexis—May I Please Speak to Jordan? Identical twins are no different from everyone else, except we look and sometimes sound exactly alike.
Phone Conversation (I Sub for JB) Was that your brother? Yep, that was Josh. I’m JB. I know who you are, silly—I called you. Uh, right. You have any siblings, Alexis? Two sisters. I’m the youngest. And the prettiest. You haven’t seen them. I don’t need to. That’s sweet. Sweet as pomegranate. Okay, that was random. That’s me. Jordan, can I ask you something? Yep. Did you get my text? Uh, yeah. So, what’s your answer? Uh, my answer. I don’t know. Stop being silly, Jordan. I’m not. Then tell me your answer. Are y’all rich? I don’t know. Didn’t your dad play in the NBA? No, he played in Italy. But still, he made a lot of money, right? It’s not like we’re opulent. Who says “opulent”? I do. You never use big words like that at school . . . I have a reputation to uphold. Is he cool? Who? Your dad. Very. So, when are you gonna introduce me? Introduce you? To your parents. I’m waiting for the right moment. Which is when? Uh— So, am I your girlfriend or not? Uh, can you hold on for a second? Sure, she says. Cover the mouthpiece, JB mouths to me. I do, then whisper to him: She wants to know are you her boyfriend. And when are you gonna introduce her to Mom and Dad. What should I tell her, JB? Tell her yeah, I guess, I mean, I don’t know. I gotta pee, JB says, running out of the room, leaving me still in his shoes. Okay, I’m back, Alexis. So, what’s the verdict, Jordan? Do you want to be my girlfriend? Are you asking me to be your girl? Uh, I think so. You think so? Well, I have to go now. Yes. Yes, what? I like you. A lot. I like you, too . . . Precious. So, now I’m Precious? Everyone calls you JB. Then I guess it’s official. Text me later. Good night, Miss Sweet— What did you call me? Uh, good night, my sweetness. Good night, Precious. JB comes running out of the bathroom. What’d she say, Josh? Come on, tell me. She said she likes me a lot, I tell him. You mean she likes me a lot? he asks. Yeah . . . that’s what I meant.
JB and I eat lunch together every day, taking bites of Mom’s tuna salad on wheat between arguments: Who’s the better dunker, Blake or LeBron? Which is superior, Nike or Converse? Only today I wait at our table in the back for twenty-five minutes, texting Vondie (home sick), eating a fruit cup (alone), before I see JB strut into the cafeteria with Miss Sweet Tea holding his precious hand.
Boy walks into a room with a girl. They come over. He says, Hey, Filthy McNasty like he’s said forever, but it sounds different this time, and when he snickers, she does too, like it’s some inside joke, and my nickname, some dirty punch line.
At practice Coach says we need to work on our mental game. If we think we can beat Independence Junior High— the defending champions, the number one seed, the only other undefeated team— then we will. But instead of drills and sprints, we sit on our butts, make weird sounds— Ohmmmmmmmm Ohmmmmmmmm— and meditate. Suddenly I get this vision of JB in a hospital. I quickly open my eyes, turn around, and see him looking dead at me like he’s just seen a ghost.
Second-Person After practice, you walk home alone. This feels strange to you, because as long as you can remember there has always been a second person. On today’s long, hot mile, you bounce your basketball, but your mind is on something else. Not whether you will make the playoffs. Not homework. Not even what’s for dinner. You wonder what JB and his pink Reebok–wearing girlfriend are doing. You do not want to go to the library. But you go. Because your report on The Giver is due tomorrow. And JB has your copy. But he’s with her. Not here with you. Which is unfair. Because he doesn’t argue with you about who’s the greatest, Michael Jordan or Bill Russell, like he used to. Because JB will not eat lunch with you tomorrow or the next day, or next week. Because you are walking home by yourself and your brother owns the world.
Third Wheel You walk into the library, glance over at the music section. You look through the magazines. You even sit at a desk and pretend to study. You ask the librarian where you can find The Giver. She says something odd: Did you find your friend? Then she points upstairs. On the second floor, you pass by the computers. Kids checking their Facebook. More kids in line waiting to check their Facebook. In the Biography section you see an old man reading The Tipping Point. You walk down the last aisle, Teen Fiction, and come to the reason you’re here. You remove the book from the shelf. And there, behind the last row of books, you find the “friend” the librarian was talking about. Only she’s not your friend and she’s kissing your brother.
tip·ping point [TIH-PING POYNT] noun The point when an object shifts from one position into a new, entirely different one. As in: My dad says the tipping point of our country’s economy was housing gamblers and greedy bankers. As in: If we get one C on our report cards, I’m afraid Mom will reach her tipping point and that will be the end of basketball. As in: Today at the library, I went upstairs, walked down an aisle, pulled The Giver off the shelf, and found my tipping point.
The main reason I can’t sleep is not because of the game tomorrow tonight, is not because the stubble on my head feels like bugs are break dancing on it, is not even because I’m worried about Dad. The main reason I can’t sleep tonight is because Jordan is on the phone with Miss Sweet Tea and between the giggling and the breathing he tells her how much she’s the apple of his eye and that he wants to peel her and get under her skin and give me a break. I’m still hungry and right about now I wish I had an apple of my own.
Surprised I have it all planned out. When we walk to the game I will talk to JB man to man about how he’s spending way more time with Alexis than with me and Dad. Except when I hear the horn, I look outside my window and it’s raining and JB is jumping into a car with Miss Sweet Tea and her dad, ruining my plan.
Conversation In the car I ask Dad if going to the doctor will kill him. He tells me he doesn’t trust doctors, that my grandfather did and look where it got him: six feet under at forty-five. But Mom says your dad was really sick, I tell him, and Dad just rolls his eyes, so I try something different. I tell him that just because your teammate gets fouled on a lay-up doesn’t mean you shouldn’t ever drive to the lane again. He looks at me and laughs so loud, we almost don’t hear the flashing blues behind us.
Game Time: 6:00 p.m. At 5:28 p.m. a cop pulls us over because Dad has a broken taillight. At 5:30 the officer approaches our car and asks Dad for his driver’s license and registration. At 5:32 the team leaves the locker room and pregame warm-ups begin without me. At 5:34 Dad explains to the officer that his license is in his wallet, which is in his jacket at home. At 5:37 Dad says, Look, sir, my name is Chuck Bell, and I’m just trying to get my boy to his basketball game. At 5:47 while Coach leads the Wildcats in team prayer, I pray Dad won’t get arrested. At 5:48 the cop smiles after verifying Dad’s identity on Google, and says, You “Da Man”! At 5:50 Dad autographs a Krispy Kreme napkin for the officer and gets a warning for his broken taillight. At 6:01 we arrive at the game but on my sprint into the gym I slip and fall in the mud.
This is my second year playing for the Reggie Lewis Wildcats and I’ve started every game until tonight, when Coach tells me to go get cleaned up then find a seat on the bench. When I try to tell him it wasn’t my fault, he doesn’t want to hear about sirens and broken taillights. Josh, better an hour too soon than a minute too late, he says, turning his attention back to JB and the guys on the court, all of whom are pointing and laughing at me.
Basketball Rule #6 A great team has a good scorer with a teammate who’s on point and ready to assist.
Josh’s Play-by-Play At the beginning of the second half we’re up twenty-three to twelve. I enter the game for the first time. I’m just happy to be back on the floor. When my brother and I are on the court together this team is unstoppable, unfadeable. And, yes, undefeated. JB brings the ball up the court. Passes the ball to Vondie. He shoots it back to JB. I call for the ball. JB finds me in the corner. I know y’all think it’s time for the pick-and-roll, but I got something else in mind. I get the ball on the left side. JB is setting the pick. Here it comes— I roll to his right. The double-team is on me, leaving JB free. He’s got his hands in the air, looking for the dish from me. Dad likes to say, When Jordan Bell is open you can take his three to the bank, cash it in, ’cause it’s all money. Tonight, I’m going for broke. I see JB’s still wide open. McDonald’s drive-thru open. But I got my own plans. The double-team is still on me like feathers on a bird. Ever seen an eagle soar? So high, so fly. Me and my wings are— and that’s when I remember: MY. WINGS. ARE. GONE. Coach Hawkins is out of his seat. Dad is on his feet, screaming. JB’s screaming. The crowd’s screaming, FILTHY, PASS THE BALL! The shot clock is at 5. I dribble out of the double-team. 4 Everything comes to a head. 3I see Jordan. 2 You want it that bad? HERE YA GO! 1 . . .
Before Today, I walk into the gym covered in more dirt than a chimney. When JB screams FILTHY’S McNasty, the whole team laughs. Even Coach. Then I get benched for the entire first half. For being late. Today, I watch as we take a big lead, and JB makes four threes in a row. I hear the crowd cheer for JB, especially Dad and Mom. Then I see JB wink at Miss Sweet Tea after he hits a stupid free throw. Today, I finally get into the game at the start of the second half. JB sets a wicked pick for me just like Coach showed us in practice, And I get double-teamed on the roll just like we expect. Today, I watch JB get open and wave for me to pass. Instead I dribble, trying to get out of the trap, and watch as Coach and Dad scream for me to pass. Today, I plan on passing the ball to JB, but when I hear him say “FILTHY, give me the ball,” I dribble over to my brother and fire a pass so hard, it levels him, the blood from his nose still shooting long after the shotclock buzzer goes off.
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www.cbsnews.com www.cbsnews.com
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It turns out he had a secret arsenal: stacks of 3x5 index cards filled with one-liners, which he kept in his desk to append to speeches.
Ronald Reagan used 3 x 5" index cards.
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pressbooks.online.ucf.edu pressbooks.online.ucf.edu
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Is Muni, is the Sage, the true Recluse! He who to none and nowhere overbound By ties of flesh, takes evil things and good Neither desponding nor exulting, such Bears wisdom’s plainest mark!
In this excerpt, Krishna is explaining yoga and mindfulness to Arjuna. He describes how the saint, or "Muni", stays awake when the world is asleep, and does not take interest in what the world lives for. "Muni" translates to "the silent one"; someone who can "control and silence their illogical thoughts". (Prasad). By practicing silence, munis are able to reach a higher level of consciousness and more spiritual holiness is achieved.
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- Jan 2023
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Local file Local file
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About twenty thousand of those cards are 3 × 5 inches and seven thousand 5 × 8 inches.
Goitein's zettelkasten is comprised of about 20,000 3 x 5" index cards and 7,000 5 x 8" index cards.
Link to: https://hypothes.is/a/TEiQ5H1rEe2_Amfzi4XXmg
While not directly confirmed (yet), due to the seeming correspondence of the number of cards and their corpus descriptions, it's likely that the 20,000 3 x 5" cards were his notes covering individual topics while the 7,000 5 x 8" cards were his notes and descriptions of a single fragment from the Cairo Geniza.
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www.amazon.com www.amazon.com
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https://www.amazon.com/dp/B08BZWJDHN/
Example of a modern day waste book for keeping track of one's accounting.
dimensions 3.5 x 5"
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Weread, for example, of Philistine incursions into the hill country, toMichmash in Benjamin (1 Samuel 13:23), and the Rephaim Valley nearJerusalem (2 Samuel 5:17–22). It was in one of these border disputes thatthe city at Khirbet Qeiyafa was conquered and destroyed.
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www.govinfo.gov www.govinfo.gov
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TIPOFF was created in 1987 for the express purpose of using biographic information drawn from intelligence products for watchlisting purposes. In 1987 TIPOFF began keeping track of suspected terrorists literally with a shoebox and 3 by 5 cards. Since then the program has evolved into a sophisticated interagency counterterrorism tool specifically designed to enhance the security of our nation's borders.
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- Dec 2022
- Nov 2022
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www.youtube.com www.youtube.com
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Victor Margolin's note taking and writing process
- Collecting materials and bibliographies in files based on categories (for chapters)
- Reads material, excerpts/note making on 5 x 7" note cards
- Generally with a title (based on visual in video)
- excerpts have page number references (much like literature notes, the refinement linking and outlining happens separately later in his mapping and writing processes)
- filed in a box with tabbed index cards by chapter number with name
- video indicates that he does write on both sides of cards breaking the usual rule to write only on one side
- Uses large pad of newsprint (roughly 18" x 24" based on visualization) to map out each chapter in visual form using his cards in a non-linear way. Out of the diagrams and clusters he creates a linear narrative form.
- Tapes diagrams to wall
- Writes in text editor on computer as he references the index cards and the visual map.
"I've developed a way of working to make this huge project of a world history of design manageable."<br /> —Victor Margolin
Notice here that Victor Margolin doesn't indicate that it was a process that he was taught, but rather "I've developed". Of course he was likely taught or influenced on the method, particularly as a historian, and that what he really means to communicate is that this is how he's evolved that process.
"I begin with a large amount of information." <br /> —Victor Margolin
"As I begin to write a story begins to emerge because, in fact, I've already rehearsed this story in several different ways by getting the information for the cards, mapping it out and of course the writing is then the third way of telling the story the one that will ultimately result in the finished chapters."<br /> —Victor Margolin
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www.legifrance.gouv.fr www.legifrance.gouv.fr
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Le règlement intérieur comporte un chapitre consacré à la discipline des élèves. Il reproduit l'échelle des sanctions prévues à l'article R. 511-13 et prévoit les modalités de mise en œuvre des mesures de prévention, de responsabilisation et d'accompagnement, notamment lorsqu'elles font suite à la réintégration d'un élève exclu temporairement pour des faits de violence. Le règlement intérieur est porté à la connaissance des membres de la communauté éducative. Tout manquement au règlement intérieur justifie la mise en œuvre d'une procédure disciplinaire ou de poursuites appropriées.
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www4.ac-nancy-metz.fr www4.ac-nancy-metz.fr
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« Le règlement intérieur comporte un chapitre consacré à la discipline des élèves. Il reproduit l'échelle des sanctions prévues à l'article R. 511-13 et prévoit les modalités de mise en œuvre des mesures de prévention, de responsabilisation et d'accompagnement, notamment lorsqu'elles font suite à la réintégration d'un élève exclu temporairement pour des faits de violence.»
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- Oct 2022
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Local file Local file
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he three-by-five inch slipsof thin paper eventually filled about eighty wooden file drawers.And he classified the notes day by day, under topical-chronologicalheadings that eventually extended from 4639 B.C. to 1949, theyear after his death.
Frederic L. Paxson kept a collection of 3 x 5 " slips of thin paper that filled eighty wooden file drawers which he organized using topical-chronologic headings spanning 4639 BCE to 1949.
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designopendata.wordpress.com designopendata.wordpress.com
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typographic experimentation.
Experimentation was something that became increasingly important even though it wasn't supported much at times.
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archive.org archive.org
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While he previously recommended using note cards of the same size, the examples in Goutor (1980) have 3x5" cards for bibliographic notes and 5x7" or larger cards for content notes. (p19, 21)
Is there a reason stated anywhere here for this discrepancy or change? One would ostensibly keep them in different places/sections of one's card index, but does the size difference help to differentiate the two to aid in sorting? Is the larger card intended to hold more long form writing?
Goutor is in Canada, so were 5x7" cards more common or standardized there in the late 1970s and early 80s?
A5 measures 148 × 210 millimeters or 5.83 × 8.27 inches, so is a bit larger than 5x7".
5x7" is a more standard photo size, so was this chosen as the result of storage options from the photography space?
5x7" is scantly available in America in 2022, but only from Hamilco. A few others make cardstock in that size but not specifically as index cards.
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- Sep 2022
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www.reddit.com www.reddit.com
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Posted byu/jackbaty4 hours agoCard sizes .t3_xib133._2FCtq-QzlfuN-SwVMUZMM3 { --postTitle-VisitedLinkColor: #9b9b9b; --postTitleLink-VisitedLinkColor: #9b9b9b; --postBodyLink-VisitedLinkColor: #989898; } I've been on-again/off-again with paper for PKM, but one thing remains consistent each time: I don't enjoy using 4x6 index cards. I much prefer 3x5-inch cards. I realize that it's irrational, but there it is.My question is if I dive into building an antinet, will I regret using 3x5 cards? I already have hundreds of them. I have dividers, holders, and storage boxes for them. I just prefer how they _feel_, as weird as that sounds.I'd like to hear if people are using 3x5 cards successfully or if you've come to regret it.
While it may be slightly more difficult to find larger metal/wood cases for the 4x6 or 5x8 cards, it's a minor nuisance and anyone who wants them will eventually find the right thing for them. Beyond this, choose the card size that feels right to you.
If you don't have an idea of what you need or like, try things out for 10-20 cards and see how it works for you, your handwriting size, and general needs. People have been using 3x5, 4x6, and even larger for hundreds of years without complaining about any major issues. If Carl Linnaeus managed to be okay with 3x5, which he hand cut by the way, I suspect you'll manage too.
Of course I won't mention to the Americans the cleverness of the A6, A5, A4 paper standards which allows you to fold the larger sizes in half to get the exact next smaller size down. Then you might get the benefit of the smaller size as well as the larger which could be folded into your collection of smaller cards, you just have to watch out for accidentally wrapping ("taco-ing") a smaller card inside of a larger one and losing it. I suppose you could hand cut your own 5" x 6" larger cards to do this if you found that you occasionally needed them.
For the pocketbook conscious, 3x5 does have the benefit of lower cost as well as many more options and flexibility than larger sizes.
At least commercial card sizes are now largely standardized, so you don't have deal with changing sizes the way Roland Barthes did over his lifetime.
My personal experience and a long history of so many manuals on the topic saying "cards of the same size" indicates that you assuredly won't have fun mixing different sized slips together. I personally use 3x5" cards in a waste book sense, but my main/permanent collection is in 4x6" format. Sometimes I think I should have done 3 x 5, but it's more like jealousy than regret, particularly when it comes to the potential of a restored fine furniture card catalog. But then again...
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web.archive.org web.archive.org
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https://web.archive.org/web/20080412071219/http://eastgate.com/catalog/Briefcase.html
Eastgate systems used to make a "3x5 Card Briefcase" to capture short notes on the go which could later "be scanned or transcribed to Tinderbox."
Tinderbox was one of the first digital tools to be used in a way very similar to zettelkasten of old, particularly by academics, who are a large portion of their power user base.
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www.getfrictionless.com www.getfrictionless.com
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Capture Cards (red) 4.00 Beautifully Useful 3″ x 5″ Index Cards (Pack of 100)I created my Capture Cards to help make it easier for me to capture ideas, make notes, and record tasks as they happen. Good tools have a way of removing frustration and stress from a workflow, and for me, these cards do just that.Just enough structure to help you capture, but not enough to get in the way.They’re printed full-bleed on 70lb (heavy and durable) premium smooth white cover stock, and you get 100 2-sided cards in each pack. They feel great in your hand, yet hold up well in your pocket.
https://web.archive.org/web/20140707053048/http://www.getfrictionless.com/products/capture-cards-red
Simple index cards, but sold with a purpose in mind: capturing notes!
One is reminded here of waste books and fleeting notes.
Image:<br />
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mleddy.blogspot.com mleddy.blogspot.com
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The casting director Marion Dougherty, in the documentary Casting By (dir. Tom Donahue, 2012): “I would keep the three-by-five card. I would put down anything that hit my mind.” The card for Dustin Hoffman (whose first screen appearance was in an episode of Naked City) notes Bob Duval’s (Robert Duvall’s) judgment that Hoffman is “v.g.” — very good. Notice the name of Blair Brown in the third screenshot. The Days and Nights of Molly Dodd is an Orange Crate Art and Musical Assumptions favorite.
The documentary Casting By (2012) shows casting director Marion Dougherty's 3 x 5" index card collection which she used for casting notes. In particular they show an example card for Dustin Hoffman with his details. In Hoffman's case, his card included the older telephone numbers with exchanges (EN2-6933 or Endicott2 6933), so these cards may have also served a contact purpose similar to more modern rolodexes. Different from them however, Dougherty's also included heights, credits, and other observations relevant to the casting process.
Screen capture from the movie
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- Aug 2022
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www.nytimes.com www.nytimes.com
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Schuetze, C. F. (2021, November 5). Vienna will start to vaccinate young children without E.U. approval. The New York Times. https://www.nytimes.com/2021/11/05/world/europe/vienna-vaccinate-young-children.html
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www.fda.gov www.fda.gov
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Commissioner. (2021, October 29). FDA Authorizes Pfizer-BioNTech COVID-19 Vaccine for Emergency Use in Children 5 through 11 Years of Age. FDA; FDA. https://www.fda.gov/news-events/press-announcements/fda-authorizes-pfizer-biontech-covid-19-vaccine-emergency-use-children-5-through-11-years-age
Tags
- emergency use authorization
- children
- FDA
- vaccine
- Pfizer-BioNTech
- USA
- safety
- effectiveness
- COVID-19
- 5-to 11-year-old
- lang:en
- is:other
Annotators
URL
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time.com time.com
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Vergales, J., & Gandhi, M. (2021, November 3). The Childhood Vaccine Debate Ignores a Crucial Point: Kids Aren’t Supposed to Die. Time. https://time.com/6113220/why-kids-should-get-covid-19-vaccine/
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www.faz.net www.faz.net
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Kinderimpfstoff gegen Corona: Stiko-Chef Mertens würde eigene Kinder jetzt nicht impfen lassen. (2021, December 2). FAZ.NET. https://www.faz.net/aktuell/politik/inland/stiko-chef-mertens-wuerde-eigene-kinder-nicht-gegen-corona-impfen-17662194.html
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www.academie-medecine.fr www.academie-medecine.fr
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Vaccination of children aged 5 to 11 against Covid-19: Don’thesitate any longer – Académie nationale de médecine | Une institution dans son temps. (2022, January 25). https://www.academie-medecine.fr/vaccination-of-children-aged-5-to-11-against-covid-19-donthesitate-any-longer/?lang=en
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twitter.com twitter.com
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Benjy Renton. (2021, November 16). New data update: Drawing from 23 states reporting data, 5.3% of kids ages 5-11 in these states have received their first dose. Vermont leads these states so far in vaccination rates for this age group—17%. The CDC will begin to report data for this group late this week. Https://t.co/LMJXl6lo6Z [Tweet]. @bhrenton. https://twitter.com/bhrenton/status/1460638150322180098
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www.nytimes.com www.nytimes.com
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Lukpat, A., & Hassan, A. (2021, November 2). Covid News: Virus Is Surging on Navajo Nation, Despite High Vaccination Rates. The New York Times. https://www.nytimes.com/live/2021/11/02/world/kids-vaccine-covid-children
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Forcertainlyagreatervarietyofcards,clippings,andsuchlikecan befiledbehind 4x6slipsthan behind3x5's.
A benefit of 4 x 6" cards is that clippings and other items can often be more easily filed along with them as opposed to the smaller 3 x 5" cards.
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shall I adopt the 3x5 slip or the 4x61
Dow indicates in 1924 that 3 x 5" and 4 x 6" are both commonly had in a range of materials the US as well as boxes or cases to keep them in. He does mention that one can also cut their own paper, indicating that this is a possibility.
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www.sciencedirect.com www.sciencedirect.com
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5-Hydroxytryptophan (5-HTP), a precursor of serotonin, is therapeutically used for several psychiatric disorders such as anxiety and depression in the clinic. However, severe side effects, including abnormal mental functions, behavioral disturbances and intolerance are associated with this treatment. 5-HTP-induced elevation of plasma and brain serotonin levels may affect blood-brain barrier (BBB) breakdown, edema formation and regional cerebral blood flow (CBF) disturbances. Breakdown of BBB to serum proteins leads to vasogenic brain edema formation and cellular injuries. However, 5-HTP-neurotoxicity is still not well known. In this investigations 5-HTP induced elevation of endogenous plasma and brain serotonin levels and its effect on BBB breakdown, edema formation neuronal injuries was examined in a rat model. Furthermore, potential role of oxidative stress and nitric oxide (NO) was evaluated. In addition, several neurochemical agents such as p-CPA (5-HT synthesis inhibitor) indomethacin (prostaglandin synthase inhibitor), diazepam (ant stress drug), cyproheptadine, ketanserin (5-HT2 receptor antagonists) and vinblastine (inhibitor of microtubule function) were examined on 5-HT neurotoxicity. Our observations suggest that 4 h after 5-HTP administrations, the endogenous serotonin levels increased by fourfold (150 mg/kg) in the plasma and brain associated with profound hyperthermia (+ 3.86 ± 0.24 °C, oxidative stress and NO upregulation. Breakdown of the BBB to Evans blue albumin (EBA) in 8 brain regions and to [131]Iodine in 14 brain regions was observed. The CBF exhibited marked reduction in all the brain regions examined. Brain edema and cellular injuries are present in the areas associated with BBB disruption. Drug treatments reduced the BBB breakdown, edema formation NO production and brain pathology. These observations are the first to point out that 5-HTP-neurotoxicity caused by BBB breakdown, edema formation and NO production is instrumental in causing adverse mental and behavioral abnormalities, not reported earlier.View chapterPurchase bookRead full chapterURL: https://www.sciencedirect.com/science/article/pii/S007477421930025X
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www.frontiersin.org www.frontiersin.org
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L-tryptophan Availability and Brain Serotonergic Activity In serotonergic neurons Trp serves as the precursor for 5-HT. The 5-HT metabolic pathway is initiated by Trp being hydroxylated to the intermediate 5-hydroxytryptophan (5-HTP), which is subsequently decarboxylated to become 5-HT. Tissue levels of 5-HTP are usually low since this substance is rapidly decaroxylated by the enzyme aromatic amino acid decarboxylase [for review see (21)]. Thus, the rate limiting step in the biosynthesis of 5-HT is the hydroxylation of Trp which is catalyzed by the enzyme tryptophan hydroxylase (TPH) (Figure 1). This enzyme is specific for 5-HT producing cells, however, it is present in two different isoforms, TPH1 and TPH2 [reviewed in (22, 23)].
5-htp metabolic pathwayIn serotonergic neurons Trp serves as the precursor for 5-HT. The 5-HT metabolic pathway is initiated by Trp being hydroxylated to the intermediate 5-hydroxytryptophan (5-HTP), which is subsequently decarboxylated to become 5-HT.
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- Jul 2022
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gist.github.com gist.github.com
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5 Learn How to Make Decisions Effectively
5 Learn How to Make Decisions Effectively
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2 Use the 5-Step Process to Get What You Want Out of Life
2 Use the 5-Step Process to Get What You Want Out of Life
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bylinetimes.com bylinetimes.com
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What is so maddening is that there are alternatives. There is an abundance of theory and arguments that could lead the way. The latest IPCC report had an entire section that doesn’t propose technofixes but instead explores how energy demand could be managed to ensure that everyone has enough to thrive while ensuring the biosphere doesn’t die.
IPCC AR6 WG III chapter 5: Demand, services and social aspects of mitigation https://hyp.is/go?url=https%3A%2F%2Freport.ipcc.ch%2Far6wg3%2Fpdf%2FIPCC_AR6_WGIII_FinalDraft_Chapter05.pdf&group=world
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report.ipcc.ch report.ipcc.ch
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Chapter 5: Demand, services and social aspects of mitigation
Public Annotation of IPCC Report AR6 Climate Change 2022 Mitigation of Climate Change WGIII Chapter 5: Demand, Services and Social Aspects of Mitigation
NOTE: Permission given by one of the lead authors, Felix Creutzig to annotate with caveat that there may be minor changes in the final version.
This annotation explores the potential of mass mobilization of citizens and the commons to effect dramatic demand side reductions. It leverages the potential agency of the public to play a critical role in rapid decarbonization.
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- Jun 2022
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What may be required, therefore, is a significant reduction of societal demand for all resources, of all kinds.”
This is consistent with the recommendations from "Ostrich or the Phoenix".IPCC latest report AR6 Ch. 5 also advocates the huge emissions reduction achievable with demand reduction.
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the inter-connectedness of the crises we face climate pollution biodiversity and 00:07:54 inequality require our change require a change in our exploitative relationship to our planet to a more holistic and caring one but that can only happen with a change in our behavior
As per IPCC AR6 WGIII, Chapter 5 outlining for the first time, the enormous mitigation potential of social aspects of mitigation - such as behavioral change - can add up to 40 percent of mitigation. And also harkening back to Donella Meadows' leverage points that point out shifts in worldviews, paradigms and value systems are the most powerful leverage points in system change.
Stop Reset Go advocates humanity builds an open source, open access praxis for Deep Humanity, understand the depths of what it means to be a living and dying human being in the context of an entwined culture. Sharing best practices and constantly crowdsourcing the universal and salient aspects of our common humanity can help rapidly transform the inner space of each human INTERbeing, which can powerfully influence outer (social) transformation.
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- May 2022
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www.usmcu.edu www.usmcu.edu
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The hyper-response aims to deflate or attack the hyperthreat by operating at the microlevel through “mesh-interventions” as well as at the macrolevel through realignment of great nation states and tribes.
In IPCC AR6 WGIII Parlence, middle actors can mediate a community scale change, which becomes a force multiplier for individual change. Supercharging individual change is what can lead to significant scale of impact through many and many types of mesh interventions. The scale of such mesh interventions will have a "trickle up" effect to affect and accelerate the actions of top down actors.
This would be truly empowering as the current agency of the individual at the grassroots level is ineffectual.
Stop Reset Go (SRG) s a simple but powerful meme that is designed to be used by anyone to effect transition. When we recognize that something is harmful and needs to change, SRG can be invoked as a simple rule for transition. The colors of the traffic light are used as a mnemonic aid. If there is a problem with a human process, then STOP. think of an alternative way of achieving the same goal that does not bring about the harm (RESET). When the alternative has been trialed, tested and proven to work without causing more progress traps, then find a way to scale and implement the solution (GO).
SRG therefore becomes a simple mesh intervention that can be applied at all scales and dimensions. Its iterative and recursive use can be tracked in the Indyweb and interventions can be modeled by AI assistants that can analyze for potential unintended consequences through connections outside the focus area of the designer, and not normally explored by the designers. This augers a truly circular design methodology of the lowest potential impact.
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“low-hanging fruit”
IPCC AR6 WGIII Chapter 5: demand, services and social aspects of mitigation identifies that up to 45% of mitigation can result from a demand-side socialization strategy and collective action mobilization. This gives us tremendous power of impact to mobilize people. The low hanging fruit can be identified by comprehensive, ongoing, deep, global conversations with the greatest diversity of actors with a common vision collectively searching for the social tipping points, leverage points and idling resources and scaling massively thru the Indyweb as a cosmolocal network (what's light we share, what's heavy we produce locally).
Climate scientist and realist Professor Kevin Anderson has argued for many years that demand side changes are the only solutions that can be implemented rapidly enough to peak emissions and drop emissions rapidly in the short term (next few years), buying time for reneewable energy solutions to scale globally.
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An analysis of “friendly forces” via a “tribal discourse” activity found that although many of humanity’s smaller and less powerful tribes are engaged in minor operations against the hyperthreat, its most powerful tribes often abet the hyperthreat (figure 2). If humanity’s tribes could be united against the hyperthreat, the current balance of probabilities, which currently lie with a hyperthreat victory and a Hothouse Earth outcome, could be recast.
This is the key idea behind mobilizing an effective global, multi-stakeholder, bottom-up response. Minor operations implies an aggregate approach that has little impact, otherwise known colloquially as "tinkering at the edge". IPCC AR6, WGIII Chapter 5 articulates this same message and for the first time, outlines that demand side system changes can play a significant role in mitigation effectiveness against the hyperthreat. It must be collectively organized individual change that scales to community scales around the globe in order to have impact, leveraging what the IPCC call "middle actors".
An effective strategy must be very time sensitive to the short time window to peak emissions so must identify all leverage points, idling resources and social tipping points available to a global bottom-up mobilization.
Tags
- awaken the sleeping giant
- cosmo-local
- social tippping points
- IPCC AR6 Chapter 5
- leverage points
- Indyweb
- Stop Reset Go
- middle actors
- idling resources
- kevin anderson
- trickle up
- IPCC AR6
- social aspects of mitigation
- demand side
- cosmolocal
- bottom-up
- mesh intervention
- SRG
- bottom up collective action
- bottom up rapid whole system change
- cosmolocalism
Annotators
URL
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www.allocine.fr www.allocine.fr
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wordpress.com wordpress.com
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"The need to engage with people in terms of evaluating them for the aim of acquiring a different point of view was one occasion this semester where the knowledge I received in class positively changed the way I approached an issue. I was patient enough to explore other perspectives, some of which disagreed with mine, so that I might learn about their opinions without bias or prejudice."
Tags
- (Major Essay) Ending/Conclusion paragraph. 5
- In my annotation, I addressed the problem of not stating how and why this circumstance benefits me in the future. In the annotation, I continued to describe how hearing other people's ideas and responding to their comments and insights during class discussions will aid me in my career aspirations.
Annotators
URL
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- Mar 2022
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www.haaretz.com www.haaretz.com
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In 1 Samuel chapter 5 we are told that after the Philistines captured the Ark of the Covenant, they took it to the Temple of Dagon in Ashdod. But this resulted in the miraculous destruction of his cult statue. Yahweh wins again.
1 Samuel 5 describes an event at the Temple of Dagon, the father of Baal, in Ashdod where the cult's statue is destroyed.
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tools.thermofisher.com tools.thermofisher.com
- Jan 2022
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0920919z.index-education.net 0920919z.index-education.net
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Les ressources génétiques marines
Arg5: Les fonds marins regorgent de ressources génétiques marines
- Le génome des espères sous marines constitue un enjeu commercial et scientifique algues: produits cosmétiques enzymes des éponges: lutte cancer (pharmacie, santé)
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- Dec 2021
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www.theguardian.com www.theguardian.com
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Walker, P., Sample, I., Stewart, H., & Adams, R. (2021, December 22). Vulnerable children aged 5-11 to be offered Covid jabs. The Guardian. https://www.theguardian.com/society/2021/dec/22/jcvi-set-to-recommend-vaccinating-vulnerable-five--to-11-year-olds
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mmcr.education mmcr.education
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may always prohibit the expression of an idea whenever society finds the idea itself offensive or disagreeable
I cant find the exact part where it specifies always being able to prohibit expression when its offensive or disagreeable. but I definitely think this is wrong
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mmcr.education mmcr.education
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Thomas: concurring O'Connor: dissenting Breyer: dissenting (with Stevens and Souter) Souter: dissenting (with Stevens, Ginsburg, and Breyer) Stevens: dissenting
O'Connor did not dissent, here is the correct conclusions:
OPINION OF THE COURT: Rehnquist CONCURRING OPINIONS: O’Connor, Thomas DISSENTING OPINIONS: Breyer, Ginsburg, Souter, Stevens
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recordsearch.naa.gov.au recordsearch.naa.gov.au
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www.revistadelauniversidad.mx www.revistadelauniversidad.mx
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Esa “formación” del hombre, que lo conduce a una estructura de la personalidad de tipo psicopático
No existe un perfil único de maltratador. Tampoco se trata de hombres agresivos ni de psicópatas. Nuestro estudio pone en cuestión los estereotipos relacionados hasta ahora con la conducta y los rasgos del maltratador, como puede ser el consumo de sustancias tóxicas y de alcohol, la vivencia de experiencias traumáticas en la edad infantil o los problemas psíquicos. En este último aspecto, los datos del patrón de personalidad de un grupo de maltratadores basados en el inventario clínico multiaxial Millon-II señalan a la compulsividad como rasgo más destacado de estas personas; no obstante, el percentil no supera el grado de normalidad, por lo que se descarta la posibilidad de una psicopatología.
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Annotators
URL
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- Nov 2021
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mmcr.education mmcr.education
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against
The Court ruled in favor of Youngstown Sheet & Tube
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mmcr.education mmcr.education
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U.S. v. O'Brien
no where is U.S. v. O'Brien mentioned in this - cases mentioned are Spence v. Washington & Street v. N.Y.
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Second Amendment
incorrect- we are looking at the first amendment here
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mmcr.education mmcr.education
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may always
The first amendment does not prohibit
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mmcr.education mmcr.education
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10 percent of the private schools available were religious, and only 5 percent of students used their vouchers at private schools.
80% of the private schools available were religious, and 97% of the students used the vouchers at private schools.
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mmcr.education mmcr.education
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sued, charging that the voucher program violated the First Amendment's free exercise clause because
Simmons- Harris sued because they thought the voucher program violated the first amendment establishment clause- NOT because of "only 10% of private schools...."
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www.thermofisher.com www.thermofisher.com
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Polypropylene containers are autoclavable. The recommended autoclave cycle for empty containers is 121°C at 15 psi for 20 minutes. Care must be taken to allow free air circulation into and out of vessels during the autoclave cycle, especially during the venting and cooling stages. If the container is not properly vented, collapse or implosion (sometimes confused with melting) can occur. When autoclaving bottles and carboys, the cap threads must be completely disengaged from the container; the cap can be set loosely over the mouth opening at a rogue angle to ensure the threads don’t inadvertently engage. Once the container is completely cooled, the cap can be aseptically tipped into place and tightened down.
This is virtually identical to pressure cooker conditions. Thus these tips likely apply equally to cooking. Moreover, I take this as evidence that is appropriate for cooking food in the pressure cooker, though it may warp under stresses (so stacking containers may cause warping).
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- Oct 2021
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mmcr.education mmcr.education
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free exercise clause
Establishment Clause
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mmcr.education mmcr.education
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They did not design to make their Government dependent on the States....
Would the dependence on the states be referring to the states making money for the national government by creating the taxes?
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mmcr.education mmcr.education
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Yes. By a vote of 6-3 the Court ruled against Youngstown Sheet & Tube.
incorrect: No. The President of the United States has no Federal statute that authorizes him to issue an order to seize private property.
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mmcr.education mmcr.education
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Truman's action can be upheld as an exercise of the president's inherent military power as commander-in-chief.
This is not true. In fact, the case brief in the book directly mentions that "the Order cannot properly be sustained as an exercise of the President's military power as commander in Chief of the Armed Forces."
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designopendata.wordpress.com designopendata.wordpress.com
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raison d’être
Reason or justification for existence.
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The typographer must take the greatest care to study how his work is read and ought to be read.
Absolutely, depending on the work and the intention behind it. You wouldn't want your audience to be confused about the readability of your work.
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- Sep 2021
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www.sciencedirect.com www.sciencedirect.com
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ZFIN: ZDB-ALT-100723-5
DOI: 10.1016/j.devcel.2021.09.005
Resource: (ZFIN Cat# ZDB-ALT-100723-5,RRID:ZFIN_ZDB-ALT-100723-5)
Curator: @Naa003
SciCrunch record: RRID:ZFIN_ZDB-ALT-100723-5
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ZFIN: ZDB-ALT-140522-5
DOI: 10.1016/j.devcel.2021.09.005
Resource: (ZFIN Cat# ZDB-ALT-140522-5,RRID:ZFIN_ZDB-ALT-140522-5)
Curator: @Naa003
SciCrunch record: RRID:ZFIN_ZDB-ALT-140522-5
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www.bostonglobe.com www.bostonglobe.com
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Pfizer says its COVID-19 vaccine is safe and effective in younger children ages 5 to 11—The Boston Globe. (n.d.). Retrieved 21 September 2021, from https://www.bostonglobe.com/2021/09/20/nation/pfizer-says-its-covid-19-vaccine-prompts-protective-immune-response-younger-children/
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STEP 5
Step 5 annotation!
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www.sciencedirect.com www.sciencedirect.com
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ZDB-ALT-110215-5
DOI: 10.1016/j.cub.2021.08.051
Resource: (ZFIN Cat# ZDB-ALT-110215-5,RRID:ZFIN_ZDB-ALT-110215-5)
Curator: @Naa003
SciCrunch record: RRID:ZFIN_ZDB-ALT-110215-5
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learn-us-east-1-prod-fleet02-xythos.content.blackboardcdn.com learn-us-east-1-prod-fleet02-xythos.content.blackboardcdn.com
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My only comfort was the knowledge that I was not alone. Huddled in the smoky hallways and making the mostof our pathetic French, my fellow students and I engaged in the sort of conversation commonly overheard inrefugee camps
atleast he isnt alone . seems like there is noone competing against eachother the teacher basically has it out for everyone
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- Aug 2021
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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RRID:ZFIN_ZDB-ALT-140522-5
DOI: 10.7554/eLife.44431
Resource: (ZFIN Cat# ZDB-ALT-140522-5,RRID:ZFIN_ZDB-ALT-140522-5)
Curator: @scibot
SciCrunch record: RRID:ZFIN_ZDB-ALT-140522-5
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elifesciences.org elifesciences.org
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RRID:ZFIN_ZDB-ALT-161012-5
DOI: 10.7554/eLife.68755
Resource: (ZFIN Cat# ZDB-ALT-161012-5,RRID:ZFIN_ZDB-ALT-161012-5)
Curator: @scibot
SciCrunch record: RRID:ZFIN_ZDB-ALT-161012-5
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Annotators
URL
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- Jul 2021
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www.sciencedirect.com www.sciencedirect.com
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Zebrafish: Tg(4xUAS:EGFP-2xFYVE)la214
DOI: 10.1016/j.cell.2019.08.001
Resource: (ZFIN Cat# ZDB-ALT-150424-5,RRID:ZFIN_ZDB-ALT-150424-5)
Curator: @ethanbadger
SciCrunch record: RRID:ZFIN_ZDB-ALT-150424-5
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www.sciencedirect.com www.sciencedirect.com
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ZFIN: ZDB-GENO-030805-5
DOI: 10.1016/j.celrep.2018.06.117
Resource: (ZFIN Cat# ZDB-GENO-030805-5,RRID:ZFIN_ZDB-GENO-030805-5)
Curator: @evieth
SciCrunch record: RRID:ZFIN_ZDB-GENO-030805-5
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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col6a1ama605003
DOI: 10.1371/journal.pone.0133986
Resource: (ZFIN Cat# ZDB-ALT-151110-5,RRID:ZFIN_ZDB-ALT-151110-5)
Curator: @mpairish
SciCrunch record: RRID:ZFIN_ZDB-ALT-151110-5
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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kdrlum19
DOI: 10.1242/dev.123059
Resource: ZFIN_ZDB-GENO-120302-5
Curator: @mpairish
SciCrunch record: RRID:ZFIN_ZDB-GENO-120302-5
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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RRID:ZDB-ALT-180417-5
DOI: 10.7554/eLife.54894
Resource: (ZFIN Cat# ZDB-ALT-180417-5,RRID:ZFIN_ZDB-ALT-180417-5)
Curator: @scibot
SciCrunch record: RRID:ZFIN_ZDB-ALT-180417-5
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- Jun 2021
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outlier-org.admin.datocms.com outlier-org.admin.datocms.com
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hen a new technology is created to increase productivity, many firms can benefit from the new technology aside from the firm that created it.
This example is taken from lecture (the pollution example is from OS Micro)
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www.sciencedirect.com www.sciencedirect.com
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ZFIN: ZDB-ALT-101227-5
DOI: 10.1016/j.cub.2021.05.042
Resource: (ZFIN Cat# ZDB-ALT-101227-5,RRID:ZFIN_ZDB-ALT-101227-5)
Curator: @Naa003
SciCrunch record: RRID:ZFIN_ZDB-ALT-101227-5
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elifesciences.org elifesciences.org
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ZDB-ALT-161103–5
DOI: 10.7554/eLife.62155
Resource: (ZFIN Cat# ZDB-ALT-161103-5,RRID:ZFIN_ZDB-ALT-161103-5)
Curator: @Naa003
SciCrunch record: RRID:ZFIN_ZDB-ALT-161103-5
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elifesciences.org elifesciences.org
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RRID:ZFIN_ZDB-ALT-191011-5
DOI: 10.7554/eLife.62196
Resource: (ZFIN Cat# ZDB-ALT-191011-5,RRID:ZFIN_ZDB-ALT-191011-5)
Curator: @scibot
SciCrunch record: RRID:ZFIN_ZDB-ALT-191011-5
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Annotators
URL
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- May 2021
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The 60-Year-Old Scientific Screwup That Helped Covid Kill | WIRED. (n.d.). Retrieved May 22, 2021, from https://www.wired.com/story/the-teeny-tiny-scientific-screwup-that-helped-covid-kill/?utm_source=twitter&utm_medium=social&utm_campaign=onsite-share&utm_brand=wired&utm_social-type=earned
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docs.microsoft.com docs.microsoft.com
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✔️ CONSIDER upgrading to the latest project file format even if you can't yet port your app. .NET Framework projects use an outdated project format. Even though the latest project format, known as SDK-style projects, was created for .NET Core and beyond, they work with .NET Framework. Having your project file in the latest format gives you a good basis for porting your app in the future.
SDK-style projects are compatible with old .NET Framework.
Tags
Annotators
URL
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via4.hypothes.is via4.hypothes.is
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(
In the previous chapter, Ar. identified one key element in having virtue of character: voluntary action. However, as Ar. explains in this chapter, decision (prohairesis) in actions is necessary in order to be virtuous. But what is decision? Here, Ar. conducts a brief initial investigation into the nature of decision. Ar. excludes the possibilities that decision is appetite, wish, or judgement. He concludes this paragraph by indicating that decision is the product of prior deliberation.
1111b4- 1112a15 No that the voluntary...chosen before other things.
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www.sciencedirect.com www.sciencedirect.com
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ZFIN: ZDB-ALT-151228-5
DOI: 10.1016/j.devcel.2020.07.015
Resource: (ZFIN Cat# ZDB-ALT-151228-5,RRID:ZFIN_ZDB-ALT-151228-5)
Curator: @Naa003
SciCrunch record: RRID:ZFIN_ZDB-ALT-151228-5
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- Apr 2021
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www.sciencedirect.com www.sciencedirect.com
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RRID:ZDB-GENO-140424-5
DOI: 10.1016/j.devcel.2021.03.027
Resource: (ZFIN Cat# ZDB-GENO-140424-5,RRID:ZFIN_ZDB-GENO-140424-5)
Curator: @Naa003
SciCrunch record: RRID:ZFIN_ZDB-GENO-140424-5
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RRID:ZDB-GENO-101201-5
DOI: 10.1016/j.devcel.2021.03.027
Resource: (ZFIN Cat# ZDB-GENO-101201-5,RRID:ZFIN_ZDB-GENO-101201-5)
Curator: @Naa003
SciCrunch record: RRID:ZFIN_ZDB-GENO-101201-5
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www.sciencedirect.com www.sciencedirect.com
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ZDB-ALT-110215-5
DOI: 10.1016/j.xpro.2021.100465
Resource: (ZFIN Cat# ZDB-ALT-110215-5,RRID:ZFIN_ZDB-ALT-110215-5)
Curator: @Naa003
SciCrunch record: RRID:ZFIN_ZDB-ALT-110215-5
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- Mar 2021
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Results for individual PALB2 variants were normalized relative to WT-PALB2 and the p.Tyr551ter (p.Y551X) truncating variant on a 1:5 scale with the fold change in GFP-positive cells for WT set at 5.0 and fold change GFP-positive cells for p.Y551X set at 1.0. The p.L24S (c.71T>C), p.L35P (c.104T>C), p.I944N (c.2831T>A), and p.L1070P (c.3209T>C) variants and all protein-truncating frame-shift and deletion variants tested were deficient in HDR activity, with normalized fold change <2.0 (approximately 40% activity) (Fig. 1a).
AssayResult: 4.5
AssayResultAssertion: Normal
StandardErrorMean: 0.23
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A total of 84 PALB2 patient-derived missense variants reported in ClinVar, COSMIC, and the PALB2 LOVD database were selected
HGVS: NM_024675.3:c.109C>A p.(Arg37Ser)
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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SUPPLEMENTARY DATA
AssayResult: 86.49
AssayResultAssertion: Not reported
PValue: 0.3376
Comment: Exact values reported in Table S3.
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To this end, 44 missense variants found in breast cancer patients were identified in the ClinVar database (https://www.ncbi.nlm.nih.gov/clinvar) and/or selected by literature curation based on their frequency of description or amino acid substitution position in the protein (Supplemental Table S1).
HGVS: NM_024675.3:c.194C>T p.(Pro65Leu)
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www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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Source Data
AssayResult: 93.33
AssayResultAssertion: Not reported
ReplicateCount: 2
StandardErrorMean: 11
Comment: Exact values reported in “Source Data” file.
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Source Data
AssayResult: 108.51
AssayResultAssertion: Not reported
ReplicateCount: 2
StandardErrorMean: 17.71
Comment: Exact values reported in “Source Data” file.
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Source Data
AssayResult: 92.32
AssayResultAssertion: Not reported
ReplicateCount: 2
StandardDeviation: 2.26
StandardErrorMean: 1.6
Comment: Exact values reported in “Source Data” file.
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