for - adjacency - new mindset built on old? - like - scientific breakthrough by forming a new idea

Breakthrough Energy, die Organisation welche dieKlima und energiepolitischen Aktivitäten Aktivitäten von Bill Gates bündelt, reduziert die Aktivitäten Ihres amerikanischen Policy-Teams dramatisch. Damit reagiert die Organisation auf die Politik der Trump-Administration, die die bisherige Form politischer Arbeit weigehend ineffizient macht. Gates will sich in Zukunft auf die Entwicklung von Firmen im Bereich saubere Energien konzentrieren. Diese Aktivitäten passen zu Trumps Ziel einer amerikanischen Energiedominanz. https://www.nytimes.com/2025/03/12/climate/bill-gates-breakthrough-energy-cuts.html?unlocked_article_code=1.3U4.gtug.AAWTHQIZC6Rj&smid=url-share

Value of knowledge in a zettelkasten as a function of reference(use/look up) frequency; links to other ideas; ease of recall without needing to look up (also a measure of usefulness); others?

Define terms and create a mathematical equation of stocks and flows around this system of information. Maybe "knowledge complexity" or "information optimization"? see: https://hypothes.is/a/zejn0oscEe-zsjMPhgjL_Q

takes into account the value of information from the perspective of a particular observer<br /> relative information value

cross-reference: Umberto Eco on no piece of information is superior: https://hypothes.is/a/jqug2tNlEeyg2JfEczmepw

Inspired by idea in https://hypothes.is/a/CdoMUJCYEe-VlxtqIFX4qA

for - social tipping points - breakthrough effect - cascading tipping points - systemiq - Bezos Earth Fund -University of Exeter - social tipping points

report details - title - The Breakthrough Effect - How to trigger a cascade of tipping points to accelerate the net zero transition - authors - Mark Meldrum - Lloyd Pinnell - Katy Brennan - Mattia Romani - Simon Sharpe - Tim Lenton - date - january 2023 - publisher -

Gut recherchierter Überblicksartikel zur zunehmenden Ausbeutung von Erdgas im Senegal und Ländern. https://www.washingtonpost.com/world/2024/01/31/senegal-natural-gas-climate-change/

• for: climate communication, climate communication - comedians, Climate Science Translated, Climate Science Breakthrough

• potential partner

  • Climate Science Breakthrough

Chadeau-Hyam, M., Wang, H., Eales, O., Haw, D., Bodinier, B., Whitaker, M., Walters, C. E., Ainslie, K. E. C., Atchison, C., Fronterre, C., Diggle, P. J., Page, A. J., Trotter, A. J., Ashby, D., Barclay, W., Taylor, G., Cooke, G., Ward, H., Darzi, A., … Elliott, P. (2022). SARS-CoV-2 infection and vaccine effectiveness in England (REACT-1): A series of cross-sectional random community surveys. The Lancet Respiratory Medicine, 0(0). https://doi.org/10.1016/S2213-2600(21)00542-7

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Feldman, J. (2021, September 25). All the Ways That “1 in 5,000 per Day” Breakthrough Infection Stat Is Nonsense. Slate. https://slate.com/technology/2021/09/breakthrough-infections-one-in-five-thousand-nonsense.html

Maier, B. F., Wiedermann, M., Burdinski, A., Klamser, P., Jenny, M. A., Betsch, C., & Brockmann, D. (2021). Germany’s current COVID-19 crisis is mainly driven by the unvaccinated (p. 2021.11.24.21266831). https://doi.org/10.1101/2021.11.24.21266831

Regev-Yochay, G., Gonen, T., Gilboa, M., Mandelboim, M., Indenbaum, V., Amit, S., Meltzer, L., Asraf, K., Cohen, C., Fluss, R., Biber, A., Nemet, I., Kliker, L., Joseph, G., Doolman, R., Mendelson, E., Freedman, L. S., Harats, D., Kreiss, Y., & Lustig, Y. (2022). 4th Dose COVID mRNA Vaccines’ Immunogenicity & Efficacy Against Omicron VOC (p. 2022.02.15.22270948). medRxiv. https://doi.org/10.1101/2022.02.15.22270948

Lipsitch, M., Krammer, F., Regev-Yochay, G., Lustig, Y., & Balicer, R. D. (2021). SARS-CoV-2 breakthrough infections in vaccinated individuals: Measurement, causes and impact. Nature Reviews Immunology, 1–9. https://doi.org/10.1038/s41577-021-00662-4

Collier, A. Y., Brown, C. M., Mcmahan, K., Yu, J., Liu, J., Jacob-Dolan, C., Chandrashekar, A., Tierney, D., Ansel, J. L., Rowe, M., Sellers, D., Ahmad, K., Aguayo, R., Anioke, T., Gardner, S., Siamatu, M., Rivera, L. B., Hacker, M. R., Madoff, L. C., & Barouch, D. H. (2021). Immune Responses in Fully Vaccinated Individuals Following Breakthrough Infection with the SARS-CoV-2 Delta Variant in Provincetown, Massachusetts (p. 2021.10.18.21265113). https://doi.org/10.1101/2021.10.18.21265113

Prof Peter Hotez MD PhD [@PeterHotez]. (2021, December 14). 6. I was really hoping we would get the holidays in before the omicron wall hit. Doesn’t look like it https://t.co/X3Kud2ybdQ [Tweet]. Twitter. https://twitter.com/PeterHotez/status/1470895433518133252

ReconfigBehSci [@SciBeh]. (2021, December 10). Useful thread! [Tweet]. Twitter. https://twitter.com/SciBeh/status/1469208352819404805

Benjamin Meyer. (2022, January 14). Here is a bit of a longer explanatory thread on our recent paper on “Infectious viral load in unvaccinated and vaccinated patients infected with SARS-CoV-2 WT, Delta and Omicron”. You can read the full paper here: Https://t.co/R2FSyck6Nn [Tweet]. @BenjaminMeyer85. https://twitter.com/BenjaminMeyer85/status/1482102496764039176

Peña-Hernández, M. A., Klein, J., Malik, A. A., Coppi, A., Kalinich, C., Vogels, C. B. F., Silva, J., Initiative, Y. S.-C.-2 G. S., Peaper, D. R., Landry, M.-L., Wilen, C., Grubaugh, N. D., Schulz, W., Omer, S. B., & Iwasaki, A. (2022). Comparison of infectious SARS-CoV-2 from the nasopharynx of vaccinated and unvaccinated individuals (p. 2021.12.28.21268460). medRxiv. https://doi.org/10.1101/2021.12.28.21268460

Carl T. Bergstrom. (2022, January 8). 1. A thread on the CDC’s recommendation to de-isolate five days after the onset of symptoms or positive test. First, a disclosure: I was paid as a consultant for this work, done in collaboration with @Color Health, which provides COVID testing services and vaccination logistics. [Tweet]. @CT_Bergstrom. https://twitter.com/CT_Bergstrom/status/1479938654579544065

Jonathan Li on Twitter: “There’s a lineage of Omicron that’s gained the R346K mutation (BA.1.1). This one could spell some trouble for the AZ mAb (tixagevimab/cilgavimab, Evusheld) that’s being used for pre-exposure prophylaxis. If you want to learn about tix/cil vs Omicron, read on 1/7” / Twitter. (n.d.). Retrieved February 6, 2022, from https://twitter.com/DrJLi/status/1487479972293853188

Omicron’s sister variant spreads faster. So why did the one we call Omicron hit first? (2022, February 2). STAT. https://www.statnews.com/2022/02/02/omicron-sister-variant-ba2-spreads-faster/

Early data indicate vaccines still protect against Omicron’s sister variant, BA.2. (2022, January 28). STAT. https://www.statnews.com/2022/01/28/early-data-indicate-vaccines-still-protect-against-omicrons-sister-variant-ba-2/

Evershed, N. (n.d.). The simple numbers every government should use to fight anti-vaccine misinformation. The Guardian. Retrieved January 30, 2022, from https://www.theguardian.com/news/datablog/ng-interactive/2022/jan/28/the-simple-numbers-every-government-should-use-to-fight-anti-vaccine-misinformation

U.S. breaks record with more than 145,000 covid-19 hospitalizations. (n.d.). Washington Post. Retrieved January 12, 2022, from https://www.washingtonpost.com/health/2022/01/10/covid-hospitalized-omicron/

Sidik, S. M. (2022). Immunity against Omicron from breakthrough infection could be a matter of timing. Nature. https://doi.org/10.1038/d41586-022-00004-x

Eric Topol. (2021, December 14). Graph of Pfizer 3rd shot (booster) vs Omicron symptomatic infection, restoring to 75% protection, significantly less compared to its effect vs Delta (95%) with 95% CI, @UKHSA data, vs unvaccinated https://ft.com/content/8a6a0ec8-fd07-49cd-a3f5-386a06269a5c by @hannahkuchler @donatopmancini @mroliverbarnes https://t.co/PHMDZGIgDj [Tweet]. @EricTopol. https://twitter.com/EricTopol/status/1470744717398720513

Should the definition of “fully vaccinated” be changed to include a booster shot? (2021, December 11). Los Angeles Times. https://www.latimes.com/science/story/2021-12-11/should-the-definition-of-fully-vaccinated-include-a-booster-shot

Wheatley, A. K., & Juno, J. A. (2021). COVID-19 vaccines in the age of the delta variant. The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(21)00688-5

COVID-19 Vaccine Breakthrough Weekly Update—Minnesota Dept. Of Health. (n.d.). Retrieved November 23, 2021, from https://www.health.state.mn.us/diseases/coronavirus/stats/vbt.html

Couzin-Frankel, J. (2021). Antiviral pills could change pandemic’s course. Science, 374(6569), 799–800. https://doi.org/10.1126/science.acx9605

To Plan B, or not to Plan B? (2021, November 2). https://www.thenakedscientists.com/articles/interviews/plan-b-or-not-plan-b

ReconfigBehSci. (2021, November 1). 2/2 from the paper ‘We speculate that the extraordinarily high antibody titers observed in vaccinated individuals who develop breakthrough infections may lead to subsequent long-term protection in those individuals.’ [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1455104597454954497

Aufrichtig, A., & Walker, A. S. (2021, October 28). Who Had Covid-19 Vaccine Breakthrough Cases? The New York Times. https://www.nytimes.com/interactive/2021/10/28/us/covid-breakthrough-cases.html

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Dolgin, Elie. ‘The Tangled History of MRNA Vaccines’. Nature 597, no. 7876 (14 September 2021): 318–24. https://doi.org/10.1038/d41586-021-02483-w.

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Iacobucci, G. (2021). Covid-19: How is vaccination affecting hospital admissions and deaths? BMJ, n2306. https://doi.org/10.1136/bmj.n2306

Wu, K. J. (2021, July 13). “Breakthrough Infections” Is Not a Helpful Term. The Atlantic. https://www.theatlantic.com/science/archive/2021/07/coronavirus-breakthrough-infections/619416/

Coronavirus vaccines cut risk of long Covid, study finds—BBC News. (n.d.). Retrieved September 2, 2021, from https://www.bbc.co.uk/news/health-58410354

Liu, Y., Arase, N., Kishikawa, J., Hirose, M., Li, S., Tada, A., Matsuoka, S., Arakawa, A., Akamatsu, K., Ono, C., Jin, H., Kishida, K., Nakai, W., Kohyama, M., Nakagawa, A., Yamagishi, Y., Nakagami, H., Kumanogoh, A., Matsuura, Y., … Arase, H. (2021). The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines (p. 2021.08.22.457114). https://doi.org/10.1101/2021.08.22.457114

Breakthrough cases aren’t the cause of the US Covid-19 surge—Vox. (n.d.). Retrieved August 11, 2021, from https://www.vox.com/22602039/breakthrough-cases-covid-19-delta-variant-masks-vaccines

Bergwerk, M., Gonen, T., Lustig, Y., Amit, S., Lipsitch, M., Cohen, C., Mandelboim, M., Gal Levin, E., Rubin, C., Indenbaum, V., Tal, I., Zavitan, M., Zuckerman, N., Bar-Chaim, A., Kreiss, Y., & Regev-Yochay, G. (2021). Covid-19 Breakthrough Infections in Vaccinated Health Care Workers. New England Journal of Medicine, 0(0), null. https://doi.org/10.1056/NEJMoa2109072

ReconfigBehSci. (2021, July 28). RT @trishgreenhalgh: ⬇️⬇️⬇️ Cower from this virus, or risk serious complications. It’s not a cold. Https://t.co/CN4hZYQwMw [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1420913883997360131

Why are fully vaccinated people testing positive for Covid? | Financial Times. (n.d.). Retrieved July 28, 2021, from https://www.ft.com/content/0f11b219-0f1b-420e-8188-6651d1e749ff

Adam Kucharski on Twitter: “Useful data 👇– quick look suggests odds ratio for detection of B.1.617.2 relative to non-B.1.617.2 in vaccinated group compared to controls is 2.7 (95% CI: 0.7-10) after one dose and 1.2 (0.4-3.6) after two...” / Twitter. (n.d.). Retrieved July 2, 2021, from https://twitter.com/AdamJKucharski/status/1400443351908892675?s=20

COVID-19 Breakthrough Case Investigations and Reporting | CDC. (2021, May 28). https://www.cdc.gov/vaccines/covid-19/health-departments/breakthrough-cases.html

Benjy Renton. (2021, May 15). Latest data from CDC on breakthrough cases (out of 115 million people fully vaccinated): - 1,359 hospitalized or fatal cases—52% female, 79% over 65, 21% asymptomatic—794 COVID-related hospitalizations—181 COVID-related deaths https://t.co/NTPBxgpcAV https://t.co/AGQnih2Ggq [Tweet]. @bhrenton. https://twitter.com/bhrenton/status/1393391680292859906

Chen, C. (2021, April 14). A Tiny Number of People Will Be Hospitalized Despite Being Vaccinated. We Have to Learn Why. ProPublica. https://www.propublica.org/article/a-tiny-number-of-people-will-be-hospitalized-despite-being-vaccinated-we-have-to-learn-why?token=4HsRcuNGpEdmAeWz4oEu5Cr56zj5_5OE

Ledford, H. (2020). Coronavirus breakthrough: Dexamethasone is first drug shown to save lives. Nature, d41586-020-01824–01825. https://doi.org/10.1038/d41586-020-01824-5