164 Matching Annotations
  1. Aug 2022
    1. Gilbert, P. B., Montefiori, D. C., McDermott, A., Fong, Y., Benkeser, D. C., Deng, W., Zhou, H., Houchens, C. R., Martins, K., Jayashankar, L., Castellino, F., Flach, B., Lin, B. C., O’Connell, S., McDanal, C., Eaton, A., Sarzotti-Kelsoe, M., Lu, Y., Yu, C., … Teams, U. S. G. (USG)/CoVPN B. (2021). Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial. MedRxiv, 2021.08.09.21261290. https://doi.org/10.1101/2021.08.09.21261290

    1. Pozzetto, B., Legros, V., Djebali, S., Barateau, V., Guibert, N., Villard, M., Peyrot, L., Allatif, O., Fassier, J.-B., Massardier-Pilonchéry, A., Brengel-Pesce, K., Yaugel-Novoa, M., Denolly, S., Boson, B., Bourlet, T., Bal, A., Valette, M., Andrieu, T., Lina, B., … Trouillet-Assant, S. (2021). Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination. Nature, 1–9. https://doi.org/10.1038/s41586-021-04120-y

    1. Dowdy, D. (2021, September 21). On the J&J booster news, keep in mind: 1. Median follow-up since 2nd dose was just 36 days, 2. Efficacy vs moderate COVID was 75% globally, and 3. Total number of cases in the US was 15. Please don’t take this to mean that a 2nd dose provides long-term increase in protection. Https://t.co/RnqDNBmwuD [Tweet]. @davidwdowdy. https://twitter.com/davidwdowdy/status/1440323242942554122

    1. Krause, P. R., Fleming, T. R., Peto, R., Longini, I. M., Figueroa, J. P., Sterne, J. A. C., Cravioto, A., Rees, H., Higgins, J. P. T., Boutron, I., Pan, H., Gruber, M. F., Arora, N., Kazi, F., Gaspar, R., Swaminathan, S., Ryan, M. J., & Henao-Restrepo, A.-M. (2021). Considerations in boosting COVID-19 vaccine immune responses. The Lancet, 4. https://doi.org/10.1016/S0140-6736(21)02046-8

  2. Apr 2022
    1. Carl T. Bergstrom. (2021, August 18). 1. There has been lots of talk about recent data from Israel that seem to suggest a decline in vaccine efficacy against severe disease due to Delta, waning protection, or both. This may have even been a motivation for Biden’s announcement that the US would be adopting boosters. [Tweet]. @CT_Bergstrom. https://twitter.com/CT_Bergstrom/status/1427767356600688646

    1. Hilda Bastian, PhD. (2021, February 6). Unofficial unnamed AstraZeneca insider says they are doing the interim analysis for the US trial of the Oxford vaccine. AstraZeneca spokesperson says 4-6 weeks till data release. Https://t.co/VUHgbHN02d One is wrong? Or they’ll release only when have FDA minimum follow-up? Https://t.co/LgjfX8AIti [Tweet]. @hildabast. https://twitter.com/hildabast/status/1357862227106095105

    1. (((Howard Forman))). (2021, June 28). There are few more compelling graphics to demonstrate how effective vaccines are: 80+% reduction in hospital admissions for the group most vaccinated. <40% reduction in admissions for the group least likely to be vaccinated. [Tweet]. @thehowie. https://twitter.com/thehowie/status/1409492774009847810

    1. Marc Lipsitch. (2021, July 20). At the risk of boiling down too much and certainly losing some detail, one way to summarize this wonderful thread is that when we think about vaccine effectiveness, we should think of 4 key variables: 1 which vaccine, 2 age of the person, 3 how long after vax, 4 vs what outcome. [Tweet]. @mlipsitch. https://twitter.com/mlipsitch/status/1417595538632060931

    1. CDC. (2022, February 4). A new @CDCMMWR study shows that people who reported always wearing masks or respirators in indoor public settings in California were less likely to test positive for #COVID19 compared with those who reported not wearing a face covering. Learn more. Http://bit.ly/MMWR7106 https://t.co/6UJ9cs60NK [Tweet]. @CDCgov. https://twitter.com/CDCgov/status/1489675180242870278

    1. ReconfigBehSci. (2021, July 19). this is how the failure to understand what efficacy means and how it relates to outcomes will be seized on over and over again. Cookie cutter fallacies require cookie cutter clarification by machine tools to be combatted effectively (at least at current levels of moderation) [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1417164191664730112

  3. Mar 2022
    1. Eran Segal. (2021, August 17). Israel data showing the decay of vaccine efficacy over time. Y-axis is cases per 1000 from July 7 to Aug 10, for unvaccinated, and for people vaccinated at different times Cases are higher in those vaxed earlier Despite world-data caveats, this seems quite compelling https://t.co/5aNz48AC8F [Tweet]. @segal_eran. https://twitter.com/segal_eran/status/1427696623988117505

  4. Feb 2022
    1. Afkhami, S., D’Agostino, M. R., Zhang, A., Stacey, H. D., Marzok, A., Kang, A., Singh, R., Bavananthasivam, J., Ye, G., Luo, X., Wang, F., Ang, J. C., Zganiacz, A., Sankar, U., Kazhdan, N., Koenig, J. F. E., Phelps, A., Gameiro, S. F., Tang, S., … Xing, Z. (2022). Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2. Cell, S0092867422001453. https://doi.org/10.1016/j.cell.2022.02.005

  5. Jan 2022
    1. ReconfigBehSci on Twitter: “RT @AliHMokdad: Vaccine effectiveness against BA.1 and BA.2. After 2 doses it was 9% (7-10%) and 13% (-26-40%) respectively for BA.1 and BA…” / Twitter. (n.d.). Retrieved January 30, 2022, from https://twitter.com/SciBeh/status/1487123660771106821

  6. Dec 2021
  7. Nov 2021
    1. Walter, E. B., Talaat, K. R., Sabharwal, C., Gurtman, A., Lockhart, S., Paulsen, G. C., Barnett, E. D., Muñoz, F. M., Maldonado, Y., Pahud, B. A., Domachowske, J. B., Simões, E. A. F., Sarwar, U. N., Kitchin, N., Cunliffe, L., Rojo, P., Kuchar, E., Rämet, M., Munjal, I., … Gruber, W. C. (2021). Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age. New England Journal of Medicine, NEJMoa2116298. https://doi.org/10.1056/NEJMoa2116298

  8. Oct 2021
    1. Mlcochova, P., Kemp, S. A., Dhar, M. S., Papa, G., Meng, B., Ferreira, I. A. T. M., Datir, R., Collier, D. A., Albecka, A., Singh, S., Pandey, R., Brown, J., Zhou, J., Goonawardane, N., Mishra, S., Whittaker, C., Mellan, T., Marwal, R., Datta, M., … Gupta, R. K. (2021). SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion. Nature, 1–6. https://doi.org/10.1038/s41586-021-03944-y

    1. Higdon, M. M., Wahl, B., Jones, C. B., Rosen, J. G., Truelove, S. A., Baidya, A., Nande, A. A., ShamaeiZadeh, P. A., Walter, K. K., Feikin, D. R., Patel, M. K., Knoll, M. D., & Hill, A. L. (2021). A systematic review of COVID-19 vaccine efficacy and effectiveness against SARS-CoV-2 infection and disease [Preprint]. Epidemiology. https://doi.org/10.1101/2021.09.17.21263549

  9. Sep 2021
    1. John Burn-Murdoch. (2021, August 23). NEW: in the last couple of weeks there have a lot of new studies out assessing vaccine efficacy, many of which have touched on the question of waning immunity. Unsurprisingly, these have prompted a lot of questions. Time for a thread to summarise what we do and don’t know: [Tweet]. @jburnmurdoch. https://twitter.com/jburnmurdoch/status/1429878189011111936

  10. Aug 2021
    1. Tim Plante, MD MHS on Twitter: “Just reported: About half of recent ICU patients with #Covid19 in #Vermont are vaccinated. Sounds like the vaccines aren’t working, right? WRONG. Vaccines are working and here’s why. But first, let’s talk a bit about unprotected sex. A thread. (Refs at the end.) 1/n https://t.co/iyQcfCDAfh” / Twitter. (n.d.). Retrieved August 27, 2021, from https://twitter.com/tbplante/status/1430222978961317896

    1. Liu, Y., Arase, N., Kishikawa, J., Hirose, M., Li, S., Tada, A., Matsuoka, S., Arakawa, A., Akamatsu, K., Ono, C., Jin, H., Kishida, K., Nakai, W., Kohyama, M., Nakagawa, A., Yamagishi, Y., Nakagami, H., Kumanogoh, A., Matsuura, Y., … Arase, H. (2021). The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines (p. 2021.08.22.457114). https://doi.org/10.1101/2021.08.22.457114

    1. (2) David Fisman on Twitter: “Here’s some really simple modeling that hopefully will help provide some insight into why having a large, unvaccinated minority in Ontario is a problem for the population as a whole.” / Twitter. (n.d.). Retrieved August 23, 2021, from https://twitter.com/DFisman/status/1427940663925092354

    1. (2) Dr Nicole E Basta on Twitter: “There is SO MUCH misunderstanding about what a #vaccine #mandate IS & what a vaccine mandate DOES. No one is calling for anyone to be banned. No one is calling for anyone to be forcibly vaccinated. Please, gather 'round and listen up, so you know what we’re talking about... 1/n” / Twitter. (n.d.). Retrieved August 23, 2021, from https://twitter.com/IDEpiPhD/status/1428410251884302336?s=20

    1. ReconfigBehSci. (2021, July 20). No it doesn’t- it reflects the statistics of what, mathematically, has to happen as more and more people are vaccinated with a vaccine of less than 100% efficacy (as all vaccines are) [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1417520720960131073

  11. Jul 2021
    1. Carl T. Bergstrom. (2021, May 27). An update on the B.1.617.2 lineage. I’m concerned. Not because of reduced vaccine efficacy, but simply because a further increase in transmissibility above B.1.1.7 would be quite bad news for countries where vaccination is low and for hopes of near-elimination everywhere. [Tweet]. @CT_Bergstrom. https://twitter.com/CT_Bergstrom/status/1398029743954432005