- Jul 2024
-
docdrop.org docdrop.org
-
the question is why are the mitochondria not doing their job why is the self not responding to insulin 00:05:34 that's the issue different tissues different reasons but the main one is the liver
for - question - health - insulin resistance - why aren't mitochondria within cells not responding to insulin?
question - health - insulin resistance - why aren't mitochondria within cells not responding to insulin? - The fat cells are being stored in the liver, resulting in - fatty liver disease - The liver stores the fat cells floating in blood (triglycerides) then recirculates it back to the cells. - The cells and liver are caught up in a vicious cycle of "hot potatos" with the fat cells.<br /> - (See Stanford explainer video above)
-
insulin takes glucose from the blood and also fats from the blood in the form of triglyceride 00:03:11 and stuffs it in cells for a rainy day
for - health - insulin and insulin resistance - simple explanation - to - insulin resistance - clear and simple explainer video - Stanford University health - insulin - simple explanation - insulin stores sugars and tryglycerides floating around in the blood into cells. - more detailed explanation - when blood glucose rises, then beta cell of pancreas start to secrete insulin to bind to glucose and put into cells for storage - Watch this clear, short video explaining insulin resistance from Stanford University - https://hyp.is/4Ymu4D1ZEe-jFfeB23zicA/docdrop.org/video/U1cr14xffrk/
-
metabolic syndrome
for - health - insulin resistance - metabolic syndrome
health - insulin resistance - metabolic syndrome - When your mitochondria doesn't work, it results in insulin resistance - Metabolic syndrome includes an enormous variety of the major diseases afflicting modernity - up to 75% of the diseases that affect modern humans and - up to 75% of today's health care costs - and includes - type 2 diabetes - hypertension - dyslipidemia - cardiovascular disease - cancer - dementia - fatty liver disease - pollycystic ovarian disease - (he didn't include strokes here but he mentions throughout his talk)
-
for - personal health - metabolic disease - insulin resistance caused by mitochondria dysfunction - interview - Dr. Robert Lustig - health - dangers of sugar in our diet
summary - Robert Lustig is a researcher and major proponent for educating the dangers of sugar as the root cause of the majority of preventable western disease - He explains how sugar and carbs are a major variable and root cause of a majority of these diseases - It is useful to look at these bodily dysfunctions from the perspective of Michael Levin, in which all these diseases of the body are problems with lower levels of the multi-scale competency architecture - https://jonudell.info/h/facet/?max=100&expanded=true&user=stopresetgo&exactTagSearch=true&any=michael+levin%2C+multi-scale+competency+architecture
-
insulin resistance is actually 00:01:14 Downstream of something even more important that we will talk about called mitochondrial dysfunction
for - health - insulin resistance - a symptom of mitochondria dysfunction
Tags
- question - health - insulin resistance - why aren't mitochondria within cells not responding to insulin?
- disease from the perspective of dysfunction of lower levels of multi-scale competency architecture
- health - insulin resistance - a symptom of mitochondria dysfunction
- health - insulin and insulin resistance
- to - health - insulin resistance - clear and short explainer video - Stanford University
- health - heart - dangers of sugar in our diet
- metabolic syndrome - insulin resistance - 75% of modern diseases afflicting modernity
- heart health
- Robert Lustig
- personal health - metabolic disease - insulin resistance caused by mitochondria dysfunction - interview - Dr. Robert Lustig
Annotators
URL
-
-
docdrop.org docdrop.org
-
but as the situation continues it may require more and more and more insulin to get the same amount 00:02:40 of glucose into the cells
for - key insight - health - insulin resistance
key insight - health - insulin resistance - This is the key to the mechanism by which insulin levels increase in the blood. - As our diet places higher levels of glucose in the blood, the pancreas responds by releasing more and more insulin to process this elevated level of insulin and the cells respond, - but the cells, especially surrounding the organs no longer store fat when a certain threshold of high insulin is reached - high amounts of visceral fat around the organs is then accompanied by fat being released by the cells into the blood stream, elevating triglyceride levels - The liver then starts to take this up and if there are now elevated trigycerides in the bloodstream, the liver and cells get locked into a vicious cycle of fat release
-
for - explanation - insulin resistance - Stanford University
explanation - insulin resistance - Standard University - great explanation from Standford University
from - Prof. Emeritus Robert Lustig on root cause of insulin resistance - https://hyp.is/RFJQrj1aEe-nIQu5Sj1fyw/docdrop.org/video/WVFMyzQE-4w/
-
-
docdrop.org docdrop.org
-
the vast majority of hypertension high blood pressure the root cause is insulin resistance metabolic disease
for - health - heart - majority of hypertension and high blood pressure is caused by insulin resistance metabolic disease
-
many of these patients had high lipids and high blood pressure and they were given beta 00:28:25 blockers and thide diuretics which as you know also have the same consequence as the statins do in in exacerbating insulin resistance
for - health - heart - Beta-blocker/thiazide diuretic combos
health - heart - Beta-blocker/thiazide diuretic combos - This combo lowers the blood pressure by - removing excess water and salt from the body and - slowing the heart rate. - These only mask the symptoms CAUSED BY INSULIN RESISTANCE
-
you can take these medications you can expose yourself to the risk of the medications 00:26:57 or or you can change the way you eat you can deal with the true underlying problem insulin resistance
for - health - heart - root cause of heart disease - lifestyle choices - dietary choice
health - heart - root causes of heart disease - lifestyle choices - dietary choice - root cause of insulin resistance is poor diet with too much sugar and carbs and other variables such as excessive alcohol - dietary changes can shift lipid particles to large, fluffy LD particles - high sugar and carbs is a main factor leading to insulin resistance
to - Root cause of insulin resistance - interview with Robert Lustig - https://hyp.is/l14UvjzwEe-cUVPwiO6lIg/docdrop.org/video/WVFMyzQE-4w/
Tags
- health - heart - majority of hypertension and high blood pressure is caused by insulin resistance metabolic disease
- health - heart - low impact statin medication vs high impact dietary change
- to - Root cause of insulin resistance - interview with Robert Lustig
- health - heart - Beta-blocker/thiazide diuretic combos only MASK SYMPTOMS OF INSULIN RESISTANCE
Annotators
URL
-
- Apr 2024
-
rforresistance.wordpress.com rforresistance.wordpress.com
-
We need to rebuild a world outside of the grip of the globalist organisations behind the coup, outside of the grip of fascist corporations who would destroy us and the planet for power and profit, outside of the grip of the unelected billionaires parasite class, far from the grip of the corrupt governments who think they are gods and we are their canon fodder, who pretend they care about our welfare while destroying our lives. These people are our civil servants but we have let them act as our masters for too long.
We need to go off the grid, off their evil grid, outside of the control of these psychopaths, these leeches, these parasites who have been bleeding us dry for too long.
they control everything, so its hard to find ways to effective resistance…
ive been thinking about this hell on earth for 20 years, and the bottleneck i found are human relations. we just have no fucking clue, how to arrange human relations to create stable groups.
im afraid this is no accident, but deliberate sabotage from above: they dont want slaves who are well-organized, self-sufficient, free. george carlin: “They don’t want well-informed, well-educated people, capable of critical thinking. … They want obedient workers. People who are just smart enough to run the machines and do the paperwork, and just dumb enough to passively accept all these increasingly shittier jobs”
possible solution: Pallas. Who are my friends. Group composition by personality type. https://milahu.github.io/alchi/src/whoaremyfriends/whoaremyfriends.html
-
- Mar 2024
-
learn-us-east-1-prod-fleet02-xythos.content.blackboardcdn.com learn-us-east-1-prod-fleet02-xythos.content.blackboardcdn.com
-
Given the already describedstrains on the Jews, the negative effect of the heat, and thegreat overloading of most of the cars, the Jews attemptedtime and again to break out of the parked train cars, asdarkness had already set in toward 7:30 p.m.
-
Withthe coming of deep darkness in the night, many Jews escapedby squeezing through the air holes after removing the barbedwire.
-
-
www.youtube.com www.youtube.com
-
0:24 "what does rebellion look like?" -- answering the question "who are my friends?" -- the system hates my answer so much that cops are threatening to throw me in jail for distributing my book for free in public here in germany...
effectively, my solution is tribalism, secession, small states, "nationalism", groups of 150 people (dunbars number) im permanent competition to each other, including permanent tribal wafare, because many small wars are better than few large wars, and because "pacifism" is a lie, pacifism is only playing for time and always leads to large wars.
Goblin mode? china calls this "tang ping" (lying flat) or "guo re tze" (just pass the day, survive this day) (via serpentza on youtube) -- aka: escapism, second life, mentalism, mind over matter, knowledge is power, living in your head, idealism, high life, city life, depression, apathy, passive resistance, pessimism, nihilism, ignorance, "i dont care", Hikikomori, NEET, MGTOW, hedonism, stupid and happy, ...
Lying flat - China's Silent Revolution<br /> by serpentza<br /> https://www.youtube.com/watch?v=uWl7njLlXLU
ps: only faggets wear socks without shoes
-
- Feb 2024
-
Local file Local file
-
“Actuallythe impact of letters from the front, which had been regarded as ex-traordinarily important, has to be considered more than harmfultoday,” he noted: “soldiers are pretty blunt when they describe thegreat problems they are fighting under, the lack of winter gear . . .insufficient food and ammunition.”
-
With smuggled letters, private diaries,and secret archives, Jewish victims made enormous efforts to leavebehind accounts of the atrocities the Nazis were committing.
-
Criticism of the disruption of publicorder was widespread, but should not be taken completely at facevalue. It undoubtedly veiled deeper moral objections that were oth-erwise difficult to articulate in Nazi Germany
-
ventuallythe criminal charges that relatives threatened to bring against hos-pitals, the dismay of local townspeople who wondered why the pa-tients “are never seen again”—“in one south German village, peas-ant women refused to sell cherries to nurses from the local statehospital”—and finally, in August 1941, the open denunciation ofinvoluntary euthanasia by Clemens August von Galen, the Catholicbishop of Münster in Westphalia, prompted Hitler to order the spe-cial killing centers dismantled.
-
he sterilization proceedings put the voices ofvictims into the historical record, an unusual occurrence in NaziGermany. Whether they were “pleading or imploring, beseechingor threatening, complaining or accusing, bitter or outraged, fright-ened or self-confident, resigned or enraged, oral or written, rhymedor unrhymed,” the appeals were generally free of the “condescend-ing” scientific language of biological racism
-
Thus, for leading opponents of the Nazis, and for the Jews andother minorities that the regime tormented, there seemed to be littlealternative but to abandon Germany altogether. Since most exilesnever returned, Germany’s political and intellectual life continuedto be structured by the Nazis long after their defeat
lack of dissenting voices means nazis shape everything
-
“Ifonly the good old days would come back again, just one more time.Why do we have to have this dreadful war, which has disrupted ourpeaceful lives, broken our happiness, and dissolved all our big andlittle hopes for a new house into nothing?”
-
But when the German cheers wouldnot stop, “Hitler sensed a popular mood, a longing for peace andreconciliation.” This was also an indication of the general content-ment with things as they were.
-
However, Germans did not want the war Hitler was determinedto wage in order to gain living space and empire.
contradiction between german desire and hitlers aspirations, they agree w/ what hes doing for the country in terms of prosperity but are reticent abt possibly sacrificing all of that in wartime
-
what he saw was an increas-ingly Nazified community in which neighbors now took notice ofKarl’s behavior and club members adjusted their own. What Karlwas resisting as he stood alongside his wife was the pressure to con-form, if only for the sake of appearances.
Tags
- concept: victimhood
- concept: fear
- nonsupporter
- nazi strategy
- concept: pressure
- concept: german future & progress
- 1936
- concept: conformity
- concept: historical narrative
- sub idea
- viewpoint
- concept: the new normal
- concept: exclusion
- main idea
- civilian
- concept: complicity
- concept: belief
- dürkefäldens
- hitler
- concept: resistance
- primary source
- antisemitism
Annotators
-
- Jan 2024
-
Local file Local file
-
Our overuse of antibiotics has led to what may be thebiggest such problem so far: the emergence of antibiotic-resistant andmuch more dangerous bacteria. Similar things happened when attemptsto eliminate malarial mosquitoes using DDT caused them to acquireDDT resistance; malarial parasites likewise acquired multi-drug-resistant genes.
Just as mosquitoes can "acquire" (evolve) DDT resistance or bacteria might evolve antiobiotic-resistance, might not humans evolve AI resistance? How fast might we do this? On what timeline? Will the pressure be slowly built up over time, or will the onset be so quick that extinction is the only outcome?
-
- Nov 2023
-
www.theatlantic.com www.theatlantic.com
-
Journalist Anna Nemtsova on Russian public society decline and losing hope after the post-Soviet period optimism wrt change. Places the turning point in 2011/2012. I worked in Moldova briefly then, and they were aiming to divert their exports to anyplace else than Russia. Kyrgyzstan had just had a revolution in spring 2010 (both towards democracy and Russian influenced). 2014 I wasn't allowed to travel from Kyrgyzstan through Moscow as P had not been seen in public for a week or two, while the Donbas conflict took place (MH17 was shot down a few months earlier). Late 2012 Russia signed onto OGP to withdraw ealry 2013 https://www.opengovpartnership.org/stories/russia-withdraws-from-open-government-partnership-too-much-transparency/ faving a controlled openness (through registered entities) above individual rights. Russia's foreign agents law is also from 2012. So seems to chime with my own experiences.
-
- Sep 2023
-
-
34:00 potential to be special, choosing path of least resistance
Tags
Annotators
URL
-
- Jan 2023
-
thedreammachine.substack.com thedreammachine.substack.com
-
Protecting and practicing fallow time is an act of resistance; it can make us feel out of step with what the prevailing culture tells us.
Rest is Resistance
Fallow time, I like that wording
-
- Dec 2022
-
Local file Local file
-
the deer reminds Chris of the trick-ster tales, that it suggests he must use his wiles to escape
-
the deer strikes back
-
Wagner emphasizes thatsuch animal tales often provided coded ways of imparting strategies forresistance and that this story has historical connections not only to the tropeof the speaking animal from African trickster mythologies like the spiderAnansi, but also perhaps, to Aesop’s animal fable
-
- Nov 2022
-
billyoppenheimer.com billyoppenheimer.com
-
The novelist and screenwriter Raymond Chandler said he avoided reading books written by someone who didn’t “take the pains” to write out the words. (It used to be common for writers to dictate into a recorder then have an assistant transcribe those words.) “You have to have that mechanical resistance,” Chandler wrote in a 1949 letter to actor/writer Alex Barris. “When you have to use your energy to put those words down, you are more apt to make them count.”
-
- Aug 2022
-
www.bbc.com www.bbc.com
-
Ro, C. (2021, November 1). Why mandatory vaccination is nothing new. https://www.bbc.com/future/article/20211029-why-mandatory-vaccination-is-nothing-new
-
-
www.biorxiv.org www.biorxiv.org
-
Iketani, S., Liu, L., Guo, Y., Liu, L., Huang, Y., Wang, M., Luo, Y., Yu, J., Yin, M. T., Sobieszczyk, M. E., Huang, Y., Wang, H. H., Sheng, Z., & Ho, D. D. (2022). Antibody Evasion Properties of SARS-CoV-2 Omicron Sublineages (p. 2022.02.07.479306). bioRxiv. https://doi.org/10.1101/2022.02.07.479306
-
-
www.nature.com www.nature.com
-
Kozlov, M. (2022). Why scientists are racing to develop more COVID antivirals. Nature, 601(7894), 496–496. https://doi.org/10.1038/d41586-022-00112-8
-
-
www.bmj.com www.bmj.com
-
Torjesen, I. (2021). Covid-19: Omicron may be more transmissible than other variants and partly resistant to existing vaccines, scientists fear. BMJ, 375, n2943. https://doi.org/10.1136/bmj.n2943
-
-
github.com github.com
-
I don't understand the hesitation here to accept a really useful addition to rspec. Maintenance burden. Forseen internal changes required to do it. Unforseen internal changes required to do it. Formatter changes to handle new output status for a spec that passed and failed It's simply not a previously design use case of RSpec. It will be hacky to implement.
-
We already have a very wide configuration API. The further we expand it the more unwieldy it becomes for users. At this point we generally require new features to be implemented first as extension gems, and then to see support, before considering including them in core.
-
- Jun 2022
-
hybridpedagogy.org hybridpedagogy.org
-
But systems of schooling and educational institutions–and much of online learning– are organized in ways that deny their voices matter. My role is to resist those systems and structures to reclaim the spaces of teaching and learning as voice affirming. Voice amplifying.
Modeling annotation and note taking can allow students to see that their voices matter in conversation with the "greats" of knowledge. We can and should question authority. Even if one's internal voice questions as one reads, that might be enough, but modeling active reading and note taking can better underline and empower these modes of thought.
There are certainly currents within American culture that we can and should question authority.
Sadly some parts of conservative American culture are reverting back to paternalized power structures of "do as I say and not as I do" which leads to hypocrisy and erosion of society.
Education can be used as a means of overcoming this, though it requires preventing the conservative right from eroding this away from the inside by removing books and certain thought from the education process that prevents this. Extreme examples of this are Warren Jeff's control of religion, education, and social life within his Mormon sect.
Link to: - Lawrence Principe examples of the power establishment in Western classical education being questioned. Aristotle wasn't always right. The entire history of Western science is about questioning the status quo. (How can we center this practice not only in science, but within the humanities?)
My evolving definition of active reading now explicitly includes the ideas of annotating the text, having a direct written conversation with it, questioning it, and expanding upon it. I'm not sure I may have included some or all of these in it before. This is what "reading with a pen in hand" (or digital annotation tool) should entail. What other pieces am I missing here which might also be included?
-
- Mar 2022
-
hackeducation.com hackeducation.com
-
www.theguardian.com www.theguardian.com
-
Al Newman. (2022, March 8). @danaparish @jennybluebird2U To your point: Https://t.co/CsULpIACoI [Tweet]. @AlNewman_. https://twitter.com/AlNewman_/status/1501056062262333441
-
-
blog.lolofit.com blog.lolofit.com
-
Valter Longo, PhD has been studying an aspect of fasting and autophagy that is fascinating enough, I wanted to include it in it’s own section. One area of his research focuses on how fasting induces differential stress resistance to make chemotherapy far more effective. In a food scarce environment, normal cells become more resistant to oxidative stress, but cancer cells don’t. Remember, cancer cells are broken cells. Something went wrong with them and they are replicating out of control. Being broken means they don’t retain all the typical functions and protective mechanisms of normal cells, like antioxidant generation. That’s one of the reasons cancer cells switch their metabolism from oxidative phosphorylation to glycolysis even in the presence of oxygen. It’s known as the Warburg effect. There are many theories on why this happens, but one is because cancer cells are more sensitive to the reactive oxygen species created during normal metabolism. Eating creates an environment where cancer cells thrive and normal cells are stressed. Cancer cells need an environment rich with sugar, growth factors (like IGF-1) and amino acids like glutamine. For normal cells, metabolism creates reactive oxygen species and triggers an immune response to deal with all the pathogens riding along on top of your meals. However, when you fast, normal cells become 1000 times more resistant to reactive oxygen species, but cancer cells do not. This same starvation-protection also makes normal cells far more resistant to chemotherapy drugs.
So fasting helps protect healthy cells and weakens cancerous ones. That's cool. But then it says cacer clles need sugar, growth factors like [[IGF-1]] and amino acids like glutamine. The [[Carnivore Diet]] is going to increse IGF-1 and amino acid levels but should starve the cancer cells of sugar. Given Dr Clemens' success treating cancer with the [[PKD]] protocol I'm inferring that it's the triad that needs to be inn place and if sugar is missing then the other factors being elevated eoesn't matter that much.
-
- Feb 2022
-
assets.publishing.service.gov.uk assets.publishing.service.gov.uk
-
Academics: Viral Evolution Scenarios, 10 February 2022. (n.d.). GOV.UK. Retrieved February 14, 2022, from https://www.gov.uk/government/publications/academics-viral-evolution-scenarios-10-february-2022
Tags
- transmissibility
- surveillance
- immune escape
- viral evolution
- COVID-19
- vaccination
- antigenic escape
- infection
- lang:en
- waning immunity
- vaccine efficacy
- severity
- therapeutic
- testing
- UK
- scenario
- antiviral drug resistance
- prediction
- protection
- heterogeneity
- variant
- immunity
- vaccine
- is:report
Annotators
URL
-
- Dec 2021
-
psyarxiv.com psyarxiv.com
-
Santos, H. C., Meyer, M., & Chabris, C. (2021). Reports of the Death of Expertise May Be Exaggerated: Limits on Knowledge Resistance in Health and Medicine. PsyArXiv. https://doi.org/10.31234/osf.io/6wy53
-
-
www.theguardian.com www.theguardian.com
-
Oladipo, G. (2021, November 14). ‘Detox’ routines won’t undo Covid vaccine, experts tell anti-vaxxers. The Guardian. https://www.theguardian.com/us-news/2021/nov/14/covid-vaccine-mandate-detox-borax-bath
-
- Nov 2021
-
www.science.org www.science.org
-
Couzin-Frankel, J. (2021). Antiviral pills could change pandemic’s course. Science, 374(6569), 799–800. https://doi.org/10.1126/science.acx9605
-
-
beforewegoblog.com beforewegoblog.com
-
The punk movement is anti-establishment, with long ties to political activism and resistance, anti-consumerist, anti-corporate, anti-authoritarian, with a strong ethic of visibility and in-your-face active expression of these sentiments.
Perfectly expresses my orientation and my love of XTC.
-
- Oct 2021
-
www.nature.com www.nature.com
-
Mallapaty, S. (2021). The search for people who never get COVID. Nature. https://doi.org/10.1038/d41586-021-02978-6
-
-
www.nature.com www.nature.com
-
Roozenbeek, J., & van der Linden, S. (2019). Fake news game confers psychological resistance against online misinformation. Palgrave Communications, 5(1), 1–10. https://doi.org/10.1057/s41599-019-0279-9
-
-
dailycaller.com dailycaller.com
-
GANDHI: Vaccine Mandates Are The Only Way To End This Public Health Emergency. (n.d.). Retrieved 4 October 2021, from https://dailycaller.com/2021/09/21/gandhi-vaccine-mandates-are-the-only-way-to-end-this-public-health-emergency/
-
-
www.gavi.org www.gavi.org
-
Five reasons why it’s a terrible idea to hold a COVID-19 party (even if you’ve been vaccinated) | Gavi, the Vaccine Alliance. (n.d.). Retrieved October 3, 2021, from https://www.gavi.org/vaccineswork/five-reasons-why-its-terrible-idea-hold-covid-19-party-even-if-youve-been
-
- Sep 2021
-
twitter.com twitter.com
-
SuzeeB🙂. (2021, September 14). Dear vaccinated, We did not take your freedom. The government did. We are not holding your freedoms to ransom. The government is. If we are a danger to you, then your vaccine doesn’t work. If it does, then you should already be free. The government has lied to you. [Tweet]. @NatalieSuB. https://twitter.com/NatalieSuB/status/1437835320628809733
-
-
www.youtube.com www.youtube.com
-
I've been wanting to read Zinn, so perhaps this is a good place to follow along? A sort of pseudo book club perhaps?
It's interesting to see Dan struggle with an obvious listicle article in Forbes as an authoritative source. This example is a great indicator that Forbes online has created far too much of a content farm to be taken seriously anymore. From what I've seen of it over the past several years it's followed the business model of The Huffington Post before Huffington sold it and cashed out. My supposition is that Forbes is providing a platform for people to get reach and isn't actually paying those writers to create their content.
Howard Zinn's A People's History of the United States
- Covering a chapter a week
- companion edition, Voices of People's History of United States by Howard Zinn and Anthony Arnov
- Erik Foner's article about Zinn
- Time, Work-Discipline, and Industrial Capitalism by E. P. Thompson *
- cultural theorist Raymond Williams' idea of resources of hope
- Resources of Hope: Culture, Democracy, Socialism by Raymond Williams
- An Indigenous People's History of the United States
-
-
twitter.com twitter.com
-
ReconfigBehSci. (2021, August 22). RT @chrischirp: Some good news from PHE’s Friday Delta tech briefing update: Two sublineages of Delta called AY.1 and AY.2 do not seem to b… [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1430638002586329088
-
- Aug 2021
-
mediaschool.indiana.edu mediaschool.indiana.edu
-
Vaccine resistance rooted in ideology, new survey shows: News: The Media School. (n.d.). Retrieved August 17, 2021, from https://mediaschool.indiana.edu/news-events/news/item.html?n=vaccine-resistance-rooted-in-ideology-new-survey-shows
-
-
www.newscientist.com www.newscientist.com
-
Page, M. L. (n.d.). UK conditions are ideal for evolving vaccine-resistant covid variants. New Scientist. Retrieved 4 August 2021, from https://www.newscientist.com/article/mg25133453-400-uk-conditions-are-ideal-for-evolving-vaccine-resistant-covid-variants/
-
- Jul 2021
-
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
-
Resistance to colistin in Acinetobacter baumannii associated with mutations in the PmrAB two-component system
PmrAB
-
-
twitter.com twitter.com
-
Eric Topol. (2021, June 9). Here’s the updated, comprehensive list of #SARSCoV2 variants that are resistant to vaccines https://t.co/JnOz3T7L28 [Tweet]. @EricTopol. https://twitter.com/EricTopol/status/1402752521970458628
-
-
twitter.com twitter.com
-
Roy Perlis. (2021, May 21). Finally: We looked at rates of vaccination among depressed/non-depressed people. 13-point gap, but not because of resistance. Underappreciated opportunity to reach people who need more help accessing vaccines? @celinegounder @CDCDirector @ASlavitt @MDaware https://t.co/EHa80z1YCH [Tweet]. @royperlis. https://twitter.com/royperlis/status/1395744126813937666
-
- Jun 2021
-
psyarxiv.com psyarxiv.com
-
Rosenfeld, D. L., & Tomiyama, A. J. (2021). Jab My Arm, Not My Morality: Perceived Moral Reproach as a Barrier to COVID-19 Vaccine Uptake. PsyArXiv. https://doi.org/10.31234/osf.io/ycbrd
-
-
twitter.com twitter.com
-
Adam Kucharski on Twitter: “A few reports from COVID situation in Taiwan that might not necessarily be what people expect: Https://t.co/7k1YKuU0qn” / Twitter. (n.d.). Retrieved June 14, 2021, from https://twitter.com/AdamJKucharski/status/1395039636204965891
-
- May 2021
-
www.thelancet.com www.thelancet.com
-
Ramanathan, M., Ferguson, I. D., Miao, W., & Khavari, P. A. (2021). SARS-CoV-2 B.1.1.7 and B.1.351 spike variants bind human ACE2 with increased affinity. The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(21)00262-0
-
-
twitter.com twitter.com
-
ReconfigBehSci on Twitter: ‘RT @enenbee: We need to be very honest with ourselves about what we know is true and what we hope is true. Https://t.co/c4lq4pWpfH’ / Twitter. (n.d.). Retrieved 18 May 2021, from https://twitter.com/SciBeh/status/1391417299878379522
-
-
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
-
Weber, T. P. (2008). Vaccine anxieties: Global science, child health and society. Bulletin of the World Health Organization, 86(9), 736. https://doi.org/10.2471/BLT.07.050369
-
-
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
-
Jansen, K. U., & Anderson, A. S. (2018). The role of vaccines in fighting antimicrobial resistance (AMR). Human Vaccines & Immunotherapeutics, 14(9), 2142–2149. https://doi.org/10.1080/21645515.2018.1476814
-
- Apr 2021
-
www.jmir.org www.jmir.org
-
Grant, L., Hausman, B. L., Cashion, M., Lucchesi, N., Patel, K., & Roberts, J. (2015). Vaccination Persuasion Online: A Qualitative Study of Two Provaccine and Two Vaccine-Skeptical Websites. Journal of Medical Internet Research, 17(5), e4153. https://doi.org/10.2196/jmir.4153
-
-
jamanetwork.com jamanetwork.com
-
Rubin, R. (2021). COVID-19 Vaccines vs Variants—Determining How Much Immunity Is Enough. JAMA, 325(13), 1241. https://doi.org/10.1001/jama.2021.3370
-
- Mar 2021
-
-
Karimi, Fariba, and Petter Holme. ‘A Temporal Network Version of Watts’s Cascade Model’. ArXiv:2103.13604 [Physics], 25 March 2021. http://arxiv.org/abs/2103.13604.
-
-
www.krisp.org.za www.krisp.org.za
-
de Oliveira T, Lutucuta S, Nkengasong J, Morais J, Paixao JP, Neto Z, Afonso P, Miranda J, David K, Ingles L, Amilton P A P R R C, Freitas H R, Mufinda F, Tessema K S , Tegally H, San E J, Wilkinson E, Giandhari J, Pillay S, Giovanetti M, Naidoo Y, Katzourakis A, Ghafari M, Singh L, Tshiabuila D, Martin D, Lessells R. (2021) A Novel Variant of Interest of SARS-CoV-2 with Multiple Spike Mutations Detected through Travel Surveillance in Africa. medRxiv. https://www.krisp.org.za/publications.php?pubid=330. Accessed 26 March 2021.
-
-
-
Wang, P., Nair, M. S., Liu, L., Iketani, S., Luo, Y., Guo, Y., Wang, M., Yu, J., Zhang, B., Kwong, P. D., Graham, B. S., Mascola, J. R., Chang, J. Y., Yin, M. T., Sobieszczyk, M., Kyratsous, C. A., Shapiro, L., Sheng, Z., Huang, Y., & Ho, D. D. (2021). Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7. Nature, 1–9. https://doi.org/10.1038/s41586-021-03398-2
-
-
jedkolko.com jedkolko.com
-
Jed. ‘The Geography of the COVID19 Third Wave | Jed Kolko’. Accessed 25 February 2021. http://jedkolko.com/2020/10/18/the-geography-of-the-covid19-third-wave/.
-
-
www.sciencedirect.com www.sciencedirect.com
-
Hidiroglu, S., Ay, P., Topuzoglu, A., Kalafat, C., & Karavus, M. (2010). Resistance to vaccination: The attitudes and practices of primary healthcare workers confronting the H1N1 pandemic. Vaccine, 28(51), 8120–8124. https://doi.org/10.1016/j.vaccine.2010.09.104
-
-
psyarxiv.com psyarxiv.com
-
Hyland, P., Vallières, F., Shevlin, M., Bentall, R. P., McKay, R., Hartman, T. K., McBride, O., & Murphy, J. (2021). Resistance to COVID-19 vaccination has increased in Ireland and the UK during the pandemic. PsyArXiv. https://doi.org/10.31234/osf.io/ry6n4
Tags
- China
- resistance
- ireland
- Russia
- COVID-19
- second wave
- is:preprint
- vaccination
- lang:en
- cross-sectional data
- statistical analysis
- public health
- pandemic
- officials
- UK
- statistics
- attitudes
- social behavior
- communication strategies
- vaccine
- vaccine hesitance
- vaccine resistance
- longitudinal
Annotators
URL
-
-
twitter.com twitter.com
-
ReconfigBehSci on Twitter: ‘RT @PsyArXivBot: Resistance to COVID-19 vaccination has increased in Ireland and the UK during the pandemic https://t.co/AgKErDr7Yj’ / Twitter. (n.d.). Retrieved 2 March 2021, from https://twitter.com/SciBeh/status/1366707710151053312
-
- Oct 2020
-
-
If the react cargo cult didn't have the JSX cowpath paved for them and acclimated to describing their app interface with vanilla javascript, they'd cargo cult around that. It's really about the path of least resistance and familiarity.
-
-
www.pnas.org www.pnas.org
-
Bosco-Lauth, A. M., Hartwig, A. E., Porter, S. M., Gordy, P. W., Nehring, M., Byas, A. D., VandeWoude, S., Ragan, I. K., Maison, R. M., & Bowen, R. A. (2020). Experimental infection of domestic dogs and cats with SARS-CoV-2: Pathogenesis, transmission, and response to reexposure in cats. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.2013102117
-
- Aug 2020
-
-
Karl Friston: Up to 80% not even susceptible to Covid-19. (2020, June 4). UnHerd. https://unherd.com/2020/06/karl-friston-up-to-80-not-even-susceptible-to-covid-19/
-
-
www.biorxiv.org www.biorxiv.org
-
Glasgow, A., Glasgow, J., Limonta, D., Solomon, P., Lui, I., Zhang, Y., Nix, M. A., Rettko, N. J., Lim, S. A., Zha, S., Yamin, R., Kao, K., Rosenberg, O. S., Ravetch, J. V., Wiita, A. P., Leung, K. K., Zhou, X. X., Hobman, T. C., Kortemme, T., & Wells, J. A. (2020). Engineered ACE2 receptor traps potently neutralize SARS-CoV-2. BioRxiv, 2020.07.31.231746. https://doi.org/10.1101/2020.07.31.231746
-
-
www.medrxiv.org www.medrxiv.org
-
SARS-CoV-2 infection induces robust, neutralizing antibody responses that are stable for at least three months | medRxiv. (n.d.). Retrieved 1 August 2020, from https://www.medrxiv.org/content/10.1101/2020.07.14.20151126v1.article-metrics
-
- Apr 2020
-
www.troyhunt.com www.troyhunt.com
-
If you're wearing the same shoes as I have so many times before where you're trying to make yourself heard and do what you ultimately believe is in the organisation's best interests
-
-
-
Moyers, S. A., & Hagger, M. S. (2020, April 20). Physical activity and sense of coherence: A meta-analysis. https://doi.org/10.31234/osf.io/d9e3k
-
- Jan 2020
-
www.nytimes.com www.nytimes.com
-
After all, the rise in antibiotic resistance doesn’t mean that we shouldn’t have invented antibiotics at all.
It does mean though, that we should try to forsee unintended consequences and not dismiss skeptics without judging the merit of their skepticism with sound scientific discussions. It is famed that Alexander Fleming who discovered the first antibiotic - penicillin, mentioned the observation of resistant bacteria and advised caution in antibiotic usage. This caution went unheeded in the subsequent golden era of antibiotics where all alternatives like phage therapy were shelved from research and development. This is the real lesson we should learn
-
- Oct 2019
-
-
indicate that even low concentrations of just a single type of antibiotic leads to resistance to multiple classes of antibiotics.
I doubt this claim, do you mean they are correlated?
-
-
www.sciencedirect.com www.sciencedirect.com
-
Overall, the low contamination level of antibiotics and high absolute abundance of ARGs indicated that ARGs previously introduced to an environment can self-amplify and persist in the environment
-
suggesting that STPs have become an important source of contamination for their receiving rivers
Read these references: Saying antibiotic resistance is proliferating in wastewater treatment plants
-
Additionally, the concentrations of antibiotics and the abundance of ARGs might increase after the sewage treatment process.
Wow, that is a strong and counter-intuitive claim. Is this rigorously determined?
-
-
www.sciencedirect.com www.sciencedirect.com
-
wastewater treatment plants are hotspots for the release of antibiotics, and transmission of diverse antibiotic resistance bacteria (ARB) as well as ARGs into various environments
That's a strong claim, not backed by strong evidence
-
Recent findings have indicated that most ARGs could not be efficiently removed by traditional anaerobic digestion treatment
-
- Jul 2019
-
newrepublic.com newrepublic.com
-
Ultimately, Pelosi is right to insist that a case must be made for beginning impeachment proceedings. But it’s her job to make that case, and failure to do so is a failure of omission. And failure to do so in a timely manner that would curtail some of the worst damage potentially produced by the administration is neglect.
Similarly, if we look at the history of the rise of Nazi Germany can we see how lack of direct resistance allowed Germany to end up in their ultimate situation with Hitler?
-
- Jun 2019
-
onlinelibrary.wiley.com onlinelibrary.wiley.com
-
introduction of Cu to agricultural soil selects for Cu resistance, but also indirectly selects for antibiotic resistance in the Cu‐resistant bacteria
-
- Mar 2019
-
criticaldigitalpedagogy.pressbooks.com criticaldigitalpedagogy.pressbooks.com
-
“Bartleby, the Scrivener,” Herman Melville
Ms. Massicot assigned this novella in her English class my junior year in high school. Fifty years later, Bartleby still informs my decision making everyday. Especially when responding to academics and educational institutions.
-
- Jan 2019
-
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
-
Adipose tissue is no longer considered to be an inert tissue that stores fat. This tissue is capable of expanding to accommodate increased lipids through hypertrophy of existing adipocytes and by initiating differentiation of pre-adipocytes. Adipose tissue metabolism exerts an impact on whole-body metabolism. As an endocrine organ, adipose tissue is responsible for the synthesis and secretion of several hormones. These are active in a range of processes, such as control of nutritional intake (leptin, angiotensin), control of sensitivity to insulin and inflammatory process mediators (tumor necrosis factor α (TNF-α), interleukin-6 (IL-6), resistin, visfatin, adiponectin, among others) and pathways (plasminogen activator inhibitor 1 (PAI-1) and acylation stimulating protein (ASP) for example). This paper reviews some of the biochemical and metabolic aspects of adipose tissue and its relationship to inflammatory disease and insulin resistance.
-
- Dec 2018
-
wendynorris.com wendynorris.com
-
Resistance Realily is 'that which resists,' according to Latour's (1987) Pragmatistinspired definition. The resistances thal designers and users encounter will change lhc ubiquitous networks of classifications and standards. Although convergence may appear at times to create an inescapable cycle of feedback and verification, the very multiplicity of people, things and processes involved mean lhat they are never locked in for all time.
Questioning the infrastructural inversion via ubiquity, material and texture, history, and power shapes the visibility and invisibility of the infrastructure that society creates for itself.
-
- Oct 2018
-
www.freitag.de www.freitag.de
-
Es ist aber auch Widerstand gegen den nicht ebenso leicht zu beschreibenden, weil sich liberal gebenden Totalitarismus des WWW selbst zu leisten.
-
-
www.atsjournals.org www.atsjournals.org
-
Low BP was more prevalent in subjects with upper airway resistance syndrome (UARS) (23%) than in subjects with obstructive sleep apnea syndrome (OSAS) (0.06%), parasomnia (0.7%), restless leg syndrome (0.9%), or psychological insomnia (0.9%).
That's an extremely high rate of hypotension in UARS. This may be what I have. If UARS causes hypotension, then sleep apnea (SA) may be different because of its link to obesity.
-
-
hybridpedagogy.org hybridpedagogy.org
-
Learning is a subversive act.
YES! In American schools you are indoctrinated with the premise: "There is no difficult material. There are only difficult learners." The "trial-by-failure" prevalent in the 70's and 80's, that if you repeat a subject you truly do not nor will not ever understand, Algebra in my case, you are somewhat "subversive" to the rest of classroom, the teacher and especially the school. Report card comments: asks too many questions/asks no questions, disruptive/sleeps in class, no effort given, won't get tutored after school labels the learner without labelling the conformity of the classroom: fit in or be shut out. Excellent point!
-
-
www.mnemotext.com www.mnemotext.com
-
When Being-out-for-something comes up against resistance, and can do nothing but ‘come up against it’, it is itself already alongside a totality of involvements. But the fact that this totality has been discovered is grounded in the disclosedness of the referential totality of significance. The experiencing of resistance—that is, the discovery of what is resistant to one’s endeavours—is possible ontologically only by reason of the disclosedness of the world.
Heidegger: "The experiencing of resistance—that is, the discovery of what is resistant to one’s endeavours—is possible ontologically only by reason of the disclosedness of the world. " || Again, does this view of disclosedness / truth foreclose a technical resistance that is not appropriable by Dasein (i.e. that which remains 'crowded out' within the horizon though not, necessarily, excluded from it).
-
- Dec 2017
-
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
-
A beneficial impact of the fat quality on insulin sensitivity is not seen in individuals with a high fat intake (> 37E%).
This is likely do to the reduced carbohydrate intake rather than increased fat intake. Since carbohydrates generally insulin sensitivity, it's likely that this additional insulin resistance is acting as a confounder (as well as, presumably, a standard deviation widener). Thus, I would expect similar results during hypocaloric carbohydrate restriction.
Tags
- fatty acid / fat / LCSFA(s) /
- diabetes / insulin sensitivity/resistance / blood sugar
- research note
- saturated fatty acid fat LCSFAs unsaturated ceramide intramuscular triglycerides intramyocellular lipid
- diabetes insulin sensitivity resistance blood sugar
- diet health lifestyle disease prevention and reversal food nutrients nutrition eat
Annotators
URL
-
- May 2017
-
nfnh2017.scholar.bucknell.edu nfnh2017.scholar.bucknell.edu
-
heat trace (heating cable)
Heat trace or heating cable is used to warm or heat underground structures, storage tanks, vessels, and instrumentation in order to maintain a specified temperature or eliminate the possibility of freezing. Heat trace or heating cable accomplish this task by adding the amount of heat energy to the process fluid that is lost from the process fluid. It is desirable to maintain a certain temperature since higher temperatures reduce viscosity, enhance combustion, and prevent freezing or crystallization of the fluid. Within the oil and gas industry, elevated temperatures are required to separate the crude oil or raw natural gas to the surface and freeze protection is required to allow refining and distribution of the fluid (Thermon South Africa (Pty.) Ltd. ). Heat trace or heating cable often utilizes resistance wire to provide a medium for voltage to pass through. Due to the resistance of the wire, the heat trace or heating cable becomes warmer and is able to use this heat to warm the underground structures that it surrounds. One material used in resistance wires is nickel-chromium (Peterjohn, Melillo, Bowles, & Steudler, 1993). Heat trace has been used since the early 1900s to ensure the proper flow of petroleum, tar, and wax through pipelines. Since then, certain products within the petroleum and chemical industries needed to be kept between specific temperatures to ensure their quality. Today, the most commonly used heat trace medium is steam (Thermon South Africa (Pty.) Ltd. ).References
Peterjohn, W. T., Melillo, J. M., Bowles, F. P., & Steudler, P. A. (1993). Soil Warming and Trace Gas Fluxes: Experimental Design and Preliminary Flux Results. Oecologia, 18-24.
Thermon South Africa (Pty.) Ltd. . (n.d.). Heat Tracing Technologies. Retrieved from Thermon South Africa (Pty.) Ltd. : file:///H:/Users/rrs020.BUCKNELL.000/Downloads/thermon-sa_heat-trace-technologies_energy-savings.pdf
-
- Mar 2017
-
rhetcompnow.com rhetcompnow.com
-
This paranoia has some pretty deep roots
Mistrust. Paranoia
-
I am an outsider who thought that perhaps I could lay a set of parallel sidetracks next to the well-worn ones of System B, an underground railway designed to lift up, carry forward, and sustain those fleeing the plight of System B.
identity
escape
-
- Aug 2016
-
books.google.ca books.google.ca
-
Juma, Calestous. 2016. Innovation and Its Enemies: Why People Resist New Technologies. Oxford University Press.
-
- May 2016
-
www.jstor.org.ezproxy.alu.talonline.ca www.jstor.org.ezproxy.alu.talonline.ca
-
nalogies between teaching and various aspects of show business or guidance counseling are more often than not excuses for having abdicated the task
On why showy teaching is bad teaching p.3
De Man, Paul. “The Resistance to Theory.” Yale French Studies, no. 63 (1982): 3–20. doi:10.2307/2929828.
-
-
christmind.info christmind.info
-
Always I AM there to pick you up, after the fall, although you do not know it at the time; firststraightening you out and then starting you onward again, by pointing out the reason for yourfall; and finally, when you are sufficiently humbled, causing you to see that these powersaccruing to you by the conscious use of My Will, My Intelligence and My Love, are allowed youonly for use in My Service, and not at all for your own personal ends.Do the cells of your body, the muscles of your arm, think to set themselves up as having aseparate will from your will, or a separate intelligence from your intelligence?No, they know no intelligence but yours, no will but yours.After a while it will be that you will realize you are only one of the cells of My Body; and thatyour will is not your will, but Mine; that what consciousness and what intelligence you have areMine wholly; and that there is no such person as you, you personally being only a physical formcontaining a human brain, which I created for the purpose of expressing in matter and Idea, acertain phase of which I could express best only in that particular form.All this may be difficult for you now to accept, and you may protest very strenuously that itcannot be, that every instinct of your nature rebels against such yielding and subordinatingyourself to an unseen and unknown power, however Impersonal or Divine.Fear not, it is only your personality that thus rebels. If you continue to follow and study MyWords, all will soon be made clear, and I will surely open up to your inner understanding manywonderful Truths that now are impossible for you to comprehend. Your Soul will rejoice singglad praises, and you will bless these words for the message they bring
I am supported through my healing, growing, learning, fashioning..........
to be able to be.. "a physical form containing a human brain, which I created for the purpose of expressing in matter and Idea, a certain phase of which I could express best only in that particular form."
It is only my personality that resists Truth.
-
- Feb 2016
-
courses.edx.org courses.edx.org
-
lleged techn o - educational innovation is generally little more than a manifestation of the divergent interests of the stakeholders involved, with any convergence rarely linked to teaching or learning
convergent interests of stakeholders does not amount to innovation teaching and learning
-
“ Whatever happened to Instructional Technology? ”. With this publication , he highlighted a nd attempted to explain the persistent failure of ICT to penetrate the world of higher education, despite several decades of effort and massive inve stment (Geoghegan, 1994)
This may situate the problem quite deeply in the history of educational ict and support claims relating to the persistence of this problem in the face of numerous interventions.
-
- Jan 2016
-
christmind.info christmind.info
-
As I said earlier, our dialoguing like this does constitute your connection with Reality, with Sanity, and you are now beginning to grasp why it is that the one who is dreaming must reach out, and why one’s Guide cannot enforce his or her presence upon the one guided. The one being guided has been engaging in the denial of Reality, the effective blocking of It, and that resistance cannot be penetrated. It isn’t actually a shell, but an insistence upon ignoring. And no one can penetrate an act of ignoring—you could say, an act of ignorance.
I need to reach out to my guide because I have been in denial of Reality and blocking it, I have been insisting on ignoring it.
-
Now, it is not necessary to be in a meditative state. At this point, it is helpful to meditate when the line of communication seems to be filled with static. It is the means of clearing the “sound” of resistance from the line of communication. Our connection is, indeed, definite, and you can hear me whether your ego is erupting or not.
It is not necessary to be in a meditative state to hear guidance although it can support the quietening of the thinking mind.
Tags
Annotators
URL
-
- Oct 2015
-
christmind.info christmind.info
-
RAJ: Paul, do not resist that feeling, but simply do not invest too much attention in it. You can move away from it, where you will not be reached by the apparent dynamics of its meaning. Even if it does not appear to resolve anything from your present point of view, you will, nevertheless, be in the best position possible to have the answer be revealed as your conscious experience. I will ask you to do that this evening before you go to sleep, in preparation for the work we will do while you are sleeping.
Paul is feeling panicky.
Raj suggests the he allow that feeling and says don't resist and don't invest too much attention in it.
Here Raj is describing how to allow.
Tags
Annotators
URL
-
-
quod.lib.umich.edu quod.lib.umich.edu
-
I describe this as “writing back” not in order to describe the volunteers as freely acting agents—we will see that this is far from the truth
like Foucault's idea that power structures predetermine forms of resistance, thus being absorbed back into the power structure?
-
-
inst-fs-iad-prod.inscloudgate.net inst-fs-iad-prod.inscloudgate.net
-
A ‘Financial Katrina’ is unfolding, which conveniently (for the developers) threatens to wipe out low-income neighbourhoods on potentially high-value land in many inner-city areas far more effectively and speedily than could be achieved through emi-nent domain.
unplanned change that will allow the government to overcome initial resistance
-
- Aug 2014
-
www.africa.upenn.edu www.africa.upenn.edu
-
First, I must confess that over the past few years I have been gravely disappointed with the white moderate. I have almost reached the regrettable conclusion that the Negro's great stumbling block in his stride toward freedom is not the White Citizen's Counciler or the Ku Klux Klanner, but the white moderate, who is more devoted to "order" than to justice; who prefers a negative peace which is the absence of tension to a positive peace which is the presence of justice; who constantly says: "I agree with you in the goal you seek, but I cannot agree with your methods of direct action"; who paternalistically believes he can set the timetable for another man's freedom; who lives by a mythical concept of time and who constantly advises the Negro to wait for a "more convenient season."
Feeling a lot of this frustration at white liberals these days.
-