Since 1993, when Mosaic first briefly experimented with native annotation, dozens of projects have tried without success.

Accessibility of Content

Motivation and Purpose

The intent behind the creation of an Annotation or the inclusion of a particular Body or Target is an important property and represented by a Motivation resource.

An increasingly conservative roster of justices has played judicial Jenga with Roe — pulling out one underpinning after another, waiting to see what will bring it down. 

The technical and theoretical details underlying clinical informatics are beyond the scope of this chapter. What follows is a concise introduction to topics and resources of general interest in this field, presented to help clinicians use information technology for the benefit of patient care.

Geological models that aid in the understanding of buried valleys are a product of recent studies in the Oak Ridges Moraine (ORM) (e.g., Barnett et al. 1998; Sharpe et al. 2002a; Russell et al 2003a; Logan et al. 2005). This work has contributed an emerging robust geological framework, yet these data have not been analysed in the context of the Laurentian valley system and its evolution over time. In contrast, conceptual hydrogeological models that might provide a framework for Laurentian valley aquifers (Fig. 1) a

In the future, robots will play a more critical role in the intelligent manufacturing field, which requires more data space and higher computing power.

This subset constituted 24% of the total frame, and was identified by Genesys Sampling Systems using a multiple regression model including covariates such as demographic variables, magazine subscription data, and data on purchasing behavior. According to Genesys Sampling Systems, the model is capable of identifying a subset of households with probability 0.6 of containing at least one age-eligible individual.

The first stage involved drawing a sample of households, using a sampling frame owned and maintained by Genesys, Inc.

Our target sample was selected from the population of English-speaking adults born between 1935 and 1952, living in Cook County, Illinois, who were sufficiently ambulatory to come to the University of Chicago for an annual, daylong visit to the Social Neuroscience Laboratory.

In the 21st century, Pacific island countries (from herein PICs) continue to leverage for tourism the attributes that have imbued them, including appeals to their cultural, geographical, and climatic allure (Pratt & Harrison, 2015).

Buried valleys have been recognized as important components of the geology of southern Ontario (Fig. 1) from the time Spencer inferred that an ancient Laurentian river network may have helped form the Great Lakes (Spencer 1881, 1890). More than 100 years later, there is no clear idea of the form, geometry, and nature of the Laurentian valley system, nor of its sedimentary fill.

It was found that the three new emerging districts (District 2, 9 and ThuDuc) are highly vulnerable to floods, but the local government still implements the plan for attracted investments in housing without an integrated flooding management. This is also in line with the development pattern of many coastal cities in Southeast Asia, as economic development can be seen as a driving factor.

The MGEs are less abundant in archaea and bacteria, conceivably due to the intense purifying selection that constrains the spread of selfish elements but nevertheless constitute up to 30% of some bacterial genomes ( Casjens 2003 ; Carle et al. 2010 ).

This classification was developed more recently in studies by Scheffer et al. (2007) and Winkler et al. (2009), which utilised molecular data sets in quantitative analyses, and are supportive of Dempewolf's Phytomyza group.

Social media networks provided immediate solutions to a few problems with those early blogging networks: they relieved the moderately heavy lift in getting started and they created the possibility of connections that were immediate, dense, and growing. But as those networks expanded, they both pulled authors away from their own domains — so much quicker to tweet than to blog, and with a much speedier potential response — and they privatized and scattered conversations.

Physiological plasticity has the potential to buffer organisms from warming by reducing the thermal sensitivity of life-sustaining processes and increasing physiological tolerances (3, 4).

The first successful attempts at farm breeding of wildV. vulpeswere initiated in the second half of the 19th cen-tury (Forester and Forester 1973) as a means of obtainingtheir valuable pelts.

The default methodology when undertaking these predictive exercises is to assume the plants themselves are static entities. However, changes in weed distributions may often reflect evolutionary change in the plants themselves, and frequently correspond to anthropogenic influences such as cropping practices (Clements et al. 2004)

Dawn Sturgess, who suffered from alcoholism, and her friend Charlie Rowley, a heroin addict, had inadvertently handled a bottle that contained the nerve agent, and were taken ill on June 30th

He has since bought a repossessed home, in the nearby town of Bluefield, that previously belonged to a pet hoarder.

This summer, Web activists plan to convene at the second Decentralized Web Summit, in San Francisco.

I selected the WordPress smilie for an arrow so I could bring up the graphic with a couple of keystrokes, as opposed to adding an image.

I have the option to link the main link for the bookmark to the Hypothesis link for “all annotations” on the source, but I’m thinking most readers will want to go directly to the source to read more.

all annotations in the source in the open for the bookmark

Deputy Prime Minister Winston Peters

We report the presence of EBV latent membrane protein 1 (LMP-1) in 93% of MS and 78% of control brains, with a greater percentage of MS brains containing CD138+ plasma cells and LMP-1–rich populations.

I am sure most Medallions are upset at the dramatic drop in upgrade success this year as well as the mega prices in SkyMiles awards cost (as well as not publishing the award charts).

as many libraries begin to function as publishers themselves, it would be interesting to see discussion around how they fit into the existing publishing ecosystem.

As the article says, 'It’s not so lonely at the top if you bring others along.' If you build a support network for others, it will support you as well."

Having an intern is actually more work (you need to carve out a lot of time to give feedback), and you are there to teach and guide. It’s not about what they are bringing to you.

In the last two centuries, there has been remarkable progress in the field of gastroenterological surgery, including the curative resection of cancers, replacement of failed organs through transplantation, increased safety of undergoing major surgeries and decreased operative morbidity through developments in minimal access surgery.

Together, these experiments elucidate a novel molecular pathway in which APP regulates, via protein-protein interaction with KCC2, GABAAR mediated inhibition in the hippocampus.

The bees understood that this card represented zero, and that its value was lower than one, with greater than 80% accuracy.

It should be noted that the number of female founders (and employees) is also significantly higher in social enterprises. According to the State of Social Enterprise Survey (2013), 38% of social ventures are led by women.

social enterprises have not only been at the forefront of ‘external’ innovations through new solutions to societal problems;

Sally Lehrman, senior director of the journalism ethics program at the Markkula Center for Applied Ethics, leads its signature Trust Project, a complex international collaboration that she began building in 2015 to strengthen public confidence in the news through accountability and transparency.

Sally Lehrman at The Trust Project.

we will pose some questions that consumers might wonder about a news organization and its people, not specific to a story. This last group of questions borrow heavily from the work on transparency and trust being done by others, including Joy Mayer at Trusting News and Sally Lehrman at The Trust Project.

Joy Mayer is a community engagement strategist based in Sarasota, Fla. Her work focuses on the continually evolving notion of audience engagement in journalism — how communicators can foster two-way conversations, collaborate with their communities and know who they’re serving and how well they’re doing it.

China’s ‘social credit system’ monitors citizen behavior and punishes them with travel bans, bans from four and five star hotels, preventing them from sending children to expensive schools, and throttling internet speeds.

That is why one company, Schumacher Homes of Akron, Ohio, has a fresh new design on offer: a house with an open floor plan, with its kitchen, dining area, and living room all flowing into one another. But then, behind the first kitchen, lies another. A “messy” kitchen. There, the preparation for or remainders from a meal or party can be deposited for later cleanup, out-of-sight, out-of-mind.

Thanks in large part to the massive popularity of “The Great British Baking Show,” Brits now, as Ptak herself has noted, have developed a taste for cakes beyond “stale sponges.”

There’s a few less apostles in Australia’s Twelve Apostles Marine National Park. In 2005, one of the largest and most intricate of the offshore sea stacks crumpled into dust in front of a watching family

Set on a space station in the 23rd century, the show revolves around galactic politics, epic alien battles, and secret agendas from a variety of factions

We’re now in a transformative stage as new tools such as ‘commenting’ emerge that can support a collective reading experience. These innovations allow readers to ‘engage’ with content in new ways.

While many libraries worldwide provide internet access and other services, libraries in cities and towns across Finland have expanded their brief to include lending e-publications, sports equipment, power tools and other “items of occasional use”. One library in Vantaa even offers karaoke.

A Prayer for Owen Meany

optics

FOLIO applications are language agnostic. In other words, apps can be written in any programming language. Apps include standard ILS modules such as circulation, cataloging, and acquisitions. Libraries and vendors can build on existing apps, or develop new apps that extend the library into areas such as campus ERP, research administration, and more

The observer can be the teacher or facilitator depending on the objectives of the activity. Group dynamics are usually presented in simulations in which there are a group of participants of three or more, while one participant acts as the nurse, the others are active observers (Jeffries, 2012).

The tectonic shift from print culture to the digital age is transforming practices of reading and writing, turning a once solitary endeavor into an interactive, dialogic, and multimedia activity. The shift is also affecting scholarly practices, albeit more gradually.

At one point, Pérez told me the name Jupyter honored Galileo, perhaps the first modern scientist. The Jupyter logo is an abstracted version of Galileo’s original drawings of the moons of Jupiter. “Galileo couldn’t go anywhere to buy a telescope,” Pérez said. “He had to build his own.”

At every turn, IPython chose the way that was more inclusive, to the point where it’s no longer called “IPython”: The project rebranded itself as “Jupyter” in 2014 to recognize the fact that it was no longer just for Python.

The school additionally offered multiple programs that both supported students in the college application process and helped educate parents about the process.

having relationships with faculty, teachers, or mentors in a STEM field can bolster students’ sense of belonging in these fields

we found advanced math and science courses advertised but not actually offered and specialized STEM programs eroded or discontinued within a few years of inception.

So I started thinking, Where can I do this [kind of math] all the time? … I started talking to my dad and he was like, “Well engineering is somewhere where you could do this … if you want to do the math all the time, then go into engineering.”

For women of color and women, in general, such developmental relationships are critical to navigate their career, and according to Eby, Allen, Evans, Ng, and Dubois (2008), mentoring aids in socialization into the organization and in career development.

Yet, across the country, 2 in 5 high schools don't offer physics, according to an Education Week Research Center analysis of data from the U.S. Department of Education's office for civil rights.

he odd result of this is that we have trending topics in networks like Twitter and Facebook, where the vast majority of updates are short and trivial, but we don’t have easily-explorable tags, hashtags or trending topics for articles and stories that are longer and more substantive.

It’s striking that we likely have author information provided as metadata on the majority of articles published today, but almost none of our reading tools expose this information in useful ways, or let us search or explore using the metadata.

n this note we determine thetorsion subgroup of the additive group of (1.1) in the case whereLhas rank 2, thatisXis a set of two elements, andcis a prime number

Of particular interest are the lower central series: G1=GG1=GG_1 =G, Gi+1=[Gi,G]Gi+1=[Gi,G]G_{i+1} = [G_i, G], i≥1i≥1i \ge 1, and, for a fixed prime number p, the Zassenhaus series (see [7, 8]).

one of my jobs was to run the mimeograph machine for their newsletter.

Most scholars of hypertext of the time pointed to Vannevar Bush's 1945 article "As We May Think" as an important precursor to the Web and as providing important guidance for necessary development. Bush's model of hypertext was much richer than that of the early Web. Among other things, he envisioned people who would put together articles (or "trails") by finding a sequence of useful pages in different sources, annotating those pages, inserting a few pages of their own, and linking it all together. While the Web had "live links", those links were limited to the original authors of the text, so The Web provided essentially none of the features necessary for Bush's more collaborative model.

not noticing when a little word like “the” gets repeated, as it was three times in the previous paragraph

“Without your critics, you’ve not got a career,” he said.

the Sunken Cities exhibition opened this week at the St. Louis Art Museum.

In what appears to be a first, a U.S. court is forcing a journal publisher to breach its confidentiality policy and identify an article's anonymous peer reviewers.

Consistent rates of ice disappearance support scientists’ prediction that the Arctic will be completely devoid of ice by 2040.

Scientists have identified a new species of reptile from prehistoric Connecticut

Nicotine is composed of a pyridine ring and a pyrrolidine ring, synthesized from two separate branches as demonstrated in Figure S1

Offer alternative working arrangements for mental-health sufferers

On the third day—Thursday—birders arrived to find the crake dead, struck by a speeding car. 

Meta is based in Canada,

So imagine my delight when, with very little preparation or context, I paid a visit to one of the sites developed by the art collective Meow Wolf, in Santa Fe, New Mexico.

Aerospace companies are in a heated race to create a hypersonic plane to replace the SR-71 Blackbird. Though retired in 1990, the SR-71 still holds the record as the fastest plane ever built, achieving a top speed of 3,540 kmh (2,200 mph).

Earning $27 million it is only $18 million away from passing  2012's The Avengers as the highest-grossing superhero film of all-time, domestically.

In 2008, Stephen Hawking, the renowned physicist who wrote A Brief History of Time, presided over the unveiling of a clockmaker’s monument to time. The Corpus Clock, created by the inventor and horologist John C. Taylor, does not look like a clock. Its shiny gold disk features 60 notches that radiate from its center. Lights race around the edges of the disc, and a spherical pendulum swings slowly beneath it.

Going into week six, Black Panther is already the second highest-grossing domestic superhero film of all-time.

While I was pregnant, I found out that women love to recount their birth experiences. It didn’t matter if it was a new mom I ran into at my doctor’s office or the grandmotherly cashier at the grocery store: Everyone had a birth story to share.

No one can say Sudan, a northern white rhino, didn’t live a full life. He was the subject of countless works of art. Famous actresses and heads of state traveled across the globe to meet him. He even had his own Tinder profile.

I will be the first and last at the bar where all the interesting conversations happen.

n our project, images needed to be checked in nearly 25% of papers ready for acceptance at our cancer research journal, requiringa time commitment of about 80 h for the initial checking during our study period of ~10 months (Table 1). Of these papers, 35.5%were found to have issues and the authors were contacted (Table 2). After the papers were returned, the images needed to bechecked again to determine whether problems were resolved and, if not, returned to the authors. We did not tr

Reconstructions from sedimentary records show that canyons undergo flushing infrequently (102- to 103-year time scales), and on passive margin canyons, this might occur only during periods of glacially lowered sea level and direct sediment supply (7, 12).

We’re officially entering the final stretch leading up to Avengers: Infinity War because Marvel just released a brand-new trailer for the movie, revealing tons of new footage and details in the process.

Theremins are unusual in that you can play them without touching them—instead, two antennae poking out of a central console detect changes in the magnetic fields surrounding them, and transform these changes into a kind of eerie, keening sound.

Jurassic World: Fallen Kingdom (June 22)

Avengers: Infinity War (May 4)

What should a superhero movie be? What can it be? With Black Panther, we finally have an answer worthy of our time.

That’s because Mars, lacking an inherent magnetic field, does not channel the sun’s energetic particles to its poles.

"But if I show you a green A, you hate it. I've had to change the colours of fonts on my power point slides in the past when giving presentations to synaesthetes."

time-space variant is one of three types that has only been properly described within the last few years.

When she thinks of a date she feels herself travel along the calendar to the right spot. She has a separate, hoop-shaped calendar for days of the week. Both have been part of her life for as long as she can remember.

“Ovals of time: time-space associations in synaesthesia”,

When someone mentions a year, I see the oval with myself at the very bottom, Christmas day to be precise. As soon as a month is given, I see exactly where that month is on the oval. As I move through the year, I am very aware of my place on the oval at the current time, and the direction I am moving in.”

there’s something unusual about the core-mantel boundary under Africa that could be having an important impact on the global magnetic field,”

Some 1,800 miles beneath southern Africa is an area called the African Large Low Shear Velocity Province, a heavy region that might be pressing down on the hot liquid iron at the Earth’s core that is responsible for generating the magnetic field in the first place.

Overwintering stinkbugs navigate like nine-year-olds in bumper cars, making as much noise as possible and banging into everything in sight: walls, doors, windows, humans.

A class of pesticides known as pyrethroids, which are used to control native stinkbugs, initially appeared to work just as well on the brown marmorated kind—until a day or two later, when more than a third of the ostensibly dead bugs rose up, Lazarus-like, and calmly resumed the business of demolition.

Reduction in cost can be achieved by the optimized design of wind farm in terms of collector system and cable layout.

Yale Collection of Musical Instruments

Many publications propose a flow-pattern identification method for two-phase flow in a microchannel,3–83. J. Shao et al., Exp. Therm. Fluid Sci. 85, 240 (2017).4. J. López et al., Exp. Therm. Fluid Sci. 76, 126 (2016).5. G. Alcan et al., Flow Meas. Instrum. 51, 55 (2016). https://doi.org/10.1016/j.flowmeasinst.2016.08.0056. P. Zhang and H. W. Jia, Chem. Eng. J. 306, 978 (2016). https://doi.org/10.1016/j.cej.2016.08.0347. M. H. Maqbool, B. Palm, and R. Khodabandeh, Exp. Therm. Fluid Sci. 46, 120 (2013). https://doi.org/10.1016/j.expthermflusci.2012.12.0028. Z. Yang et al., Appl. Therm. Eng 120, 654 (2017). and visual observation has proved the preferred method for identifying gas–liquid two-phase flow patterns.

Early inventories of emission sources show that electric power generation in India is mostly done using a polluting fossil fuel like coal and to some extent oil. Oil and petroleum products for transport are also mostly imported.

We thus hypothesize

To use a GIAN-encoder for cancer cell identification, a cell-specific ligand is necessary. Aptamers are oligonucleic acid molecules that have specificity and affinity to a wide range of targets that vary from small molecules to cancer cells.46,47 In contrast to antibodies, aptamers are cost-effective chemical antibodies that can be chemically modified and synthesized using an automatic DNA synthesizer, ensuring reproducibility from batch to batch. Many aptamers have been selected by cell-SELEX methods.48–50

In this study, a new colloidal gold quick card (TAB quick test card) was developed with the aid of colloidal gold immunochromatographic assay. This test card showed more rapidness and convenience for rapid detection of A. acidoterrestris in apple juice.

Most genetic pest controls for V. inaequalis rely on gene-for-gene interactions [3], such that the infection outcome is determined by the interaction between the products from a specific locus in the plant (the main resistance R gene) and a gene from the pathogen (avirulence gene).

Apple (Malus × domestica Borkh.) is one of the most important fruit crops in temperate regions. As a long‐lived and woody perennial tree species, apple is affected by numerous environmental stresses, leading to the economic losses.

Environmental abiotic stresses such as drought, heat, cold and high salinity affect plant growth, productivity and distribution.

Some bacteria will swim toward chemicals that suggest a potential reward, such as food.

In addition, around 144 million people weredisplaced by disasters in between 2008 and 2014, and many of them were exacerbated byclimate change with increasing frequency and intensity.

"We don't just have a skeleton," said one of the nodosaur researchers involved. "We have a dinosaur as it would have been."

In the 21st century, at the beginning of the post-industrial era, with the development of global trade and rapid rise in economic transactions, complex and competitive environments are formed (Dobbs 2014). By identifying opportunities and threats, organizations can improve their reactions in these competitive environments. One of the structural factors in any organization is Human Resources (HR). Employees are one of the critical assets for organizations to sustain their competitive advantages by utilizing specific knowledge and skills (Ahmed et al. 2013). Performance appraisal (PA)

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We also see glimpses of other actors, like Woody Harrelson's Star Wars universe debut as Tobias Beckett and Emilia Clarke (Game of Thrones) as Qi'Ra.

A 2015 study of self-checkouts with handheld scanners,

William Holman Hunt, “The Lady of Shalott”

the notably coldblooded mammals

An elegant black forest cake.

An episode in the third season of the TV show “Black Mirror” portrays a world in which people spend nearly all their time using their phones to rate virtually everyone else on a five-star scale.

Indeed, perhaps the most obvious thing to send (though it’s a bit macabre) would just be whole cryonically preserved humans (and, yes, they should keep well at the temperature of interstellar space!). Of course, it’s ironic how similar this is to the Egyptian idea of making mummies—though our technology is better (even if we still haven’t yet solved the problem of cryonics).

right now there are just four spacecraft outside our solar system (and another one that’s headed there), and there are under 100 spacecraft more-or-less intact on various planetary surfaces (not counting hard landings, melted spacecraft on Venus, etc.). And at some level a spacecraft itself is a great big “message”, illustrating lots of technology and so on.

This is their ‘afterlife’!” They successfully transmitted some essence of their life to a world far beyond their own.

They focus on what happens at the time of the trip or stay, eventually taking into account the preparations and ensuing memories. On the other hand, these works do not pay attention to the way in which the instantaneous experience falls within the individual’s life trajectory, or in which way it depends on a previous tourist experience and influences subsequent experiences1.

Swastika Night has some obvious successors, notably George Orwell’s 1984, published 12 years later, Philip K. Dick’s The Man in the High Castle, and Margaret Atwood’s The Handmaid’s Tale.

Burdekin was born in 1896 in Derbyshire, England. Her parents wouldn’t allow her go to Oxford, as her brothers had, so she married an Olympic rower, had two daughters, immigrated to Australia, started writing, left her husband, and then returned to England. The 1930s were her most fecund creative period, when she wrote 13 novels, six of which were published.