701 Matching Annotations
  1. Mar 2024
  2. Feb 2024
    1. The volunteer ‘Readers’ were instructed to write out the words andsentences on small 4 x 6-inch pieces of paper, known as ‘slips’.

      Volunteer 'Readers' for the Oxford English Dictionary were encouraged to write down interesting headwords along with their appearances in-situ along with the associated bibliographical information. The recommended paper size was 4 x 6-inch pieces of paper which were commonly called 'slips'.

      (Double check this against the historical requests from James Murray.)

  3. Jan 2024
    1. it doesn't matter how good it is they just refuse to look at it you know i had argument daniel dennett two three years ago we were at a conference and and i said you know what about a public debate

      for - adjacency - Rupert Sheldrake - Daniel Dennett - Michael Levin

      adjacency - between - Rupert Sheldrake - Daniel Dennett - Michael Levin - adjacency statement - 6 degrees of separation between - Rupert Sheldrake - Daniel Dennett - Michael Levin - Rupert met Daniel and challenged him to a debate, which Daniel flatly refused. - Daniel has coauthored paper with Michael Levin - Michael's ideas adopted from William James's definition of intelligence parallels Sheldrake's ideas of future to past trajectory of mental causation

    1. l'article 6 de la Déclaration des Droits de l'Homme et du Citoyen rédigé le 26 00:05:06 août 1789 place le mérite au cœur de l'organisation sociale tous les citoyens étant égaux à ses yeux sont également admissibles à toute dignité place et emploi public selon leur capacité et 00:05:19 sans autre distinction que celle de leur vertuus et de leurs talents
  4. Dec 2023
    1. Avery Templates for 4 x 6" products:

      • Avery 8386 postcards 2 per sheet (template compatibility 5889)
      • Avery 5292 Shipping Labels 1 per Sheet White (template compatibility 5454, 5614)
      • Avery 5454 Print or Write Multi-Use Labels 6" x 4" 1 per Sheet White (template compatibility 5292, 5614)
      • Avery 5389 Postcards 4" x 6" 2 per Sheet White (template compatibility 15389)
  5. Nov 2023
    1. As to the mechanics of research, I take notes on four-by-six indexcards, reminding myself about once an hour of a rule I read long agoin a research manual, “Never write on the back of anything.”

      Barbara Tuchman took her notes on four-by-six inch index cards.

      She repeated the oft-advised mantra to only write on one side of a sheet.


      What manual did she read this in? She specifically puts quotes on "Never write on the back of anything." so perhaps it might be something that could be tracked down?

      Who was the earliest version of this quote? And was it always towards the idea of cutting up slips or pages and not wanting to lose material on the back? or did it also (later? when?) include ease-of-use and user interface features even when not cutting things up?

      At what point did double sided become a thing for personal printed materials? Certainly out of a duty to minimize materials, but it also needed the ability to duplex print pages or photocopy them that way.

  6. Oct 2023
    1. https://en.wikipedia.org/wiki/Shmita

      During shmita, the land is left to lie fallow and all agricultural activity, including plowing, planting, pruning and harvesting, is forbidden by halakha (Jewish law).

      The sabbath year (shmita; Hebrew: שמיטה, literally "release"), also called the sabbatical year or shǝvi'it (שביעית‎, literally "seventh"), or "Sabbath of The Land", is the seventh year of the seven-year agricultural cycle mandated by the Torah in the Land of Israel and is observed in Judaism.

    1. When the ark of the covenant was returned to Israel, the people of Beth-shemesh set up a large stone upon which they offered burnt offerings and presented sacrifices to Yahweh (1 Samuel 6:14–15).
  7. Sep 2023
    1. Theexercisesthatfollow havebeengroupedinthethreecategories already explained.Whereatransposing instrumenthasbeenrequired,thegivenopeningisprintedhereasthepartwouldbewrittenforthatinstrument;i.e.theopeningmaterialisnotatconcertpitch,butalreadyinthetransposedkey.Exercises6d,6hand6nareexamplesof thismethodwhichisdifferentfromthelayoutinMusic TheoryinPractice,Grade5,SectionI.Inwriting yourmelodiestrytoremember:1)towriteinastylethatwill suitthegivenopening;2)tokeep withinthecompassofthegiveninstrumentandtowrite idiomatically, tryingtoimaginehowthemusicwillsoundinperformance;3)toplanthestructureofyourmelody,dependingonwhatisasked(itcanbehelpfultosketchintheprincipalcadences andmodulationsbefore tryingtowrite anypartofyourcontinuation-alterationsoradjustmentscanbemadelater,ifnecessary);4)toincludenon-harmonynotes,whichwillhelpyourmelodytoflowiftheyaresuitableand well-placed;5) to consider the harmonic implications of your melodic line;6) to consider the overall shape, balance and direction of your completed melody;

      Exercises are per category. Instructions are given on how to approach melody writing. This is followed by actual exercises for the student to complete.

  8. Aug 2023
    1. https://www.lochby.com/collections/frontpage/products/venture-pouch<br /> Lochby Venture Pouch<br /> $44.00

      Acquired one of these in early 2023 on sale?

      several internal sections including for pens. <br /> will easily fit a handful or so of 4 x 6" index cards for quick travel

  9. Jul 2023
    1. "I keep a dated diary of sorts on index cards, though they rarely go past one card a day."This is something I haven't heard of before. So, you journal/diary on index cards, one per day?

      reply to u/taurusnoises (Bob Doto) at tk

      Yep, for almost a full year now on 4x6" index cards. (Receipts for the kids: https://boffosocko.com/wp-content/uploads/2023/07/wp-1688411021709-scaled.jpg)

      Previously I'd used a Hobonichi Cousin (page per day) journal for this. (Perhaps I should have stayed with the A6 size instead of the larger A5 for consistency?) Decades ago (around 1988ish?) I had started using a 2 page per day DayTimer pocket planners (essentially pre-printed/timed index cards spiral bound into monthly booklets which they actually shipped in index card-like plastic boxes for storage/archival purposes). Technically I've been doing a version of this for a really long time in one form or another.

      It generally includes a schedule, to do lists (bullet journal style), and various fleeting notes/journaling similar to the older Memindex format, just done on larger cards for extra space. I generally either fold them in half for pocket storage for the day or carry about in groups for the coming week(s) when I'm away from my desk for extended periods (also with custom blank index card notebooks/pads).

      I won't go into the fact that in the 90's I had a 5,000+ person rolodex... or an index card (in the entertainment they called them buck slips) with the phone numbers and names of \~100 people I dealt with regularly when early brick cell phones didn't have great (or any) storage/functionality.

  10. Jun 2023
    1. Indeed the mainstream embraces almost anything edgy; although once the label is applied it is no longer on the edge.

      Once a movement becomes mainstream it's no longer sortout by the masses.

    2. emergence of other confrontational art and design movements, including Punk and Grunge, sought to unhinge dominant methods and mannerisms, but were ultimately absorbed into the mass culture.

      This is an example of underground turned mainstream.

    3. Despite its anti-establishment symbolism, Cubistic, Futuristic and Expressionistic veneers, he argued, would capture consumers’ attention better than a hundred slogans.

      The rawness of the avant-garde's talent connects to the public better than a structured sortout slogan. It speaks the language of the public.

    4. Yet when an intrepid commercial artist attempted to push the boundaries of design, they had to be cognizant of what industrial designer Raymond Loewy called MAYA (Most Advanced Yet Acceptable).

      Basically the underground talent is too raw to be publicized on its own so it needs to be watered down to be acceptable to become mainstream.

    1. At 9¢/card these are very expensive in comparison to bulk cards which usually can be found for 1-2¢/card. The difference however is in the luxuriousness of the silky smooth texture. Whether you're writing with your favorite fountain pen or a carefully chosen pencil. I don't know if these are the same brand of Bristol cards that Vladimir Nabokov used for his writing, but one could easily image him using such lovely material.

      These provide a very smooth writing experience for fountain pens, gel pens and pencils. I particularly love the way my Tennessee Reds and Blackwing 602s glide over their surface. In comparison to some Japanese stationery, I'd put these cards somewhere between tsuru tsuru (slippery) and sara sara (smooth). If you're looking for a toothier paper, you'll definitely want to look elsewhere. They take fountain pens pretty well with no feathering or ghosting. My juiciest fountain pen dries in about 15 seconds, while a drier extra fine is dry in about 7 seconds, so it may take some care not to smear ink if you're on the messier end of the spectrum.

      Pencil erases reasonably well, though there may be some minimal residual ghosting here. At 205 gsm, they've got a satisfying thickness unseen in most index cards and one is unlikely to rip or crinkle them when erasing. They're also thick enough that the wettest Sharpie won't bleed much less ghost through. You have to hold a card up to a backlight to see the appearance of any ghosting through it and even then, not well.

      For the sticklers used to using standard 4 x 6" index cards, one should take note that the dimensions of these are slightly shorter in both dimensions—they're closer to 3.94" x 5.91". This means that you might have to take some care that while flipping through mixed company of cards your Exacompta can potentially hide between larger imperial sized cards. They're also close to, but not quite A6 in size either (105 x 148.5 mm or 4.1 x 5.8 inches).

  11. May 2023
  12. Apr 2023
    1. 2.10-6 Space II

      The dual space of \(l^1\) is \(l^\infty\).

    Tags

    Annotators

    1. (6-10+ minutes) engaging videos that appear to do well on YouTube

      This number(6-10minutes) is appealing to most viewers as it is concise and delivers a information in short bursts. It is ideal for quick tutorials, news and entertainment.

  13. Mar 2023
    1. 312 Oak Midget Tray WWeesCoverEquipped same as]No.324,price.55CTohold cards14x3.No.423.Equippedasabove,tohold65Ccards 24x4, priceNo. 533. Standard size.to hold card 3x5, equip-ped as above,price..........No. 7- Nickel ....PrepaidinU. S.onreceiptofpriceNo. 324OakMidgetTraytheCoverWeis75cNo. 644. To hold cards4x6,equipped$1.10(StyleNos.312,423.533and644)asabove......(Style No. 324,213.335and446.)Send for catalog showing many other time-saving office devices. Our goods are soldyour dealer does not carry our line we can supply you direct from the factory.To hold cards 24x4. lengthof tray2%in..equippedwithAtoZindexand100record cards 45cNo. 213. To hold cards 14x3in,, lenght of tray 24in..equipped asabove40cNo.335.Standardsize,tohold3x5 cards.equipped asabove50c80cNo. 446. To hold 4x6 cards,equipped asabove.Any of these trays sent pre-paid in U. S. on receipt ofpriceby stationers everywhere. IfNo. 6 Union St.The WeisManufacturing Co.,Monroe,Mich.,U. S.A.Please mention SYSTEM when writing to advertisers

      Notice the 1 1/4" x 3" cards, 2 1/4 x 4" cards in addition to the 3 x 5" and 4 x 6".

    1. The width of the drawers of both McDowell & Craig and Steelcase desks is just wide enough to accommodate two rows of 4 x 6" index cards side by side with enough space that one might insert a sizeable, but thin divider between them

      I suspect that this is a specific design choice in a world in which card indexes often featured in the office environment of the mid-twenty first century.

      Were other manufacturers so inclined to do this? Is there any evidence that this was by design? Did people use it for this? Was there a standard drawer width?

      The metal inserts to section off the desk drawer area could have also been used for this sort of purpose and had cut outs to allow for expanding and contracting the interior space.

      Keep in mind that some of these tanker desks were also manufactured with specific spaces or areas intended for typewriters or for storing them.

    1. wretch

      可憐的人

    2. emulating

      to copy something achieved by someone else and try to do it as well as they have

    3. brooded

      籠罩

    4. haughty

      傲慢的

    5. But now the queen, who fear’d for Turnus’ life

      This is Turnus ignores the advice of the queen, and insist on going fighting with Aeneas , so the queen is worried about he

    6. But now the queen, who fear’d for Turnus’ life

      Why the queen feared turnus' life? And why is the advice the queen gives to he?

    7. The golden belt

      Turnus wears Pallas's belt as his trophy

    8. loquacious

      : full of excessive talk

    9. squadrons

      : a unit of military organization

    10. presage

      : something that foreshadows or portends a future event

    11. lance

      :a steel-tipped spear carried by mounted knights or light cavalry

    12. infringe

      to encroach upon in a way that violates law or the rights of another

    13. Undaunted

      courageously resolute especially in the face of danger or difficulty

    14. panacee

      a remedy for all ills or difficulties

    15. ‘T is Pallas, Pallas gives this deadly blow.”

      When Aeneas saw the golden belt, he recalled Pallas. This made him out of his mind and take revenge for Pallas by killing Turnus.

    16. adjure

      to command solemnly under or as if under oath or penalty of a curse

    17. Laurentum

      The original Italy’s capital

    18. nostrils

      either of the two openings in the nose through which air moves when you breath

    19. swains

      a young man who loves, or is having a relationship with, a woman

    20. persecute

      Treat someone unfairly or cruelly over a long period

    21. banish’d

      send someone away ,especially from their country, and not allow them to come back

    22. vaunting

      to make a vain display of one's own worth or attainments : BRAG 自誇

    23. obviate

      排除 to anticipate and prevent (something, such as a situation) or make (an action) unnecessary

    24. hawk

      鷹 any of numerous diurnal birds of prey belonging to a suborder (Falcones of the order Falconiformes) and including all the smaller members of this group

    25. balmy

      Mild and pleasant

    1. Analog Supplies

      I should mention that the Stockroom Plus 4 x 6" cards I got a while back are great with even my juiciest fountain pens. They're some of the least expensive gridded cards I've been able to find and are a fraction of the cost of the Exacompta.

  14. Feb 2023
    1. As noted by the IE SA, the HTML publication of contact information was not considered necessary by Facebook’s Security Team and was subsequently discontinued117. The EDPB considers that the analysis of the principle of data minimisation (Article 5(1)(c) GDPR) is relevant for the necessity assessment on the basis of Article 6(1)(b) GDPR118. Consequently, the EDPB further finds that such analysis should have complemented the LSA’s assessment on the necessity of the processing for the performance of the contract, with specific regard to the publication of the contact information in the HTML source code on the Instagram website. The EDPB considers that the IE SA could not have concluded that the publication of the contact information of child users in the HTML source code may be regarded as

      EDPB rightly smacks the IE SA around a bit for generally cocking this all up.

    2. Assessment of processing on the basis of Article 6(1)(f) GDPR‌

      Now we're moving on to #legitimate_interests and Article 6(1)(f)

    1. then select Close

      While there is an [ X ] close button for this window, the buttons at the bottom right are OK, Cancel, and Help. There is no close button.

      I'd update the docs to say Cancel instead,

    2. verify the server name is the instance of SQL Server containing the SSISDB catalog, and the path shows SSIS Tutorial Deployment

      My path said /SSISDB/SSIS Tutorial and there didn't seem to be a way to change it - that field was visible but disabled (grayed out).

      After pressing the Connect button to the right of Authentication, the Path changed to match the documentation and became editable.

    3. On the Select Packages page, you should see all six packages from the SSIS Tutorial. In the Packages list, select Lesson 6.dtsx, then select Next.

      At this step I encountered the following error: "One or more selected packages are not ready. Review the Status column for more information."

      The Status column said: "Microsoft.SqlServer.Dts.Pipeline.ComponentVersionMismatchException: The version of Get Error Description is not compatible with this version of the DataFlow. [[The version or pipeline version or both for the specified component is higher than the current version. This package was probably created on a new version of DTS or the component than is installed on the current PC.]] at Microsoft.SqlServer.Dts.Pipeline.ManagedComponentHost.HostCheckAndPerformUpgrade(IDTSManagedComponentWrapper100 wrapper, Int32 lPipelineVersion)"

      I was able to resolve this by changing the value Configuration Properties > General > TargetServerVersion from SQL Server 2022 to SQL Server 2019.

      Thanks to a hint found here: https://johnkilleenblog.wordpress.com/2019/10/08/ssis-script-component-mismatch-error/

  15. Jan 2023
    1. May 19, 2004 #1 Hello everyone here at the forum. I want to thank everyone here for all of the helpful and informative advice on GTD. I am a beginner in the field of GTD and wish to give back some of what I have received. What is posted below is not much of tips-and-tricks I found it very helpful in understanding GTD. The paragraphs posted below are from the book Lila, by Robert Pirsig. Some of you may have read the book and some may have not. It’s an outstanding read on philosophy. Robert Pirsig wrote his philosophy using what David Allen does, basically getting everything out of his head. I found Robert Pirsigs writing on it fascinating and it gave me a wider perspective in using GTD. I hope you all enjoy it, and by all means check out the book, Lila: An Inquiry Into Morals. Thanks everyone. arthur

      Arthur introduces the topic of Robert Pirsig and slips into the GTD conversation on 2004-05-19.

      Was this a precursor link to the Pile of Index Cards in 2006?

      Note that there doesn't seem to be any discussion of any of the methods with respect to direct knowledge management until the very end in which arthur returns almost four months later to describe a 4 x 6" card index with various topics he's using for filing away his knowledge on cards. He's essentially recreated the index card based commonplace book suggested by Robert Pirsig in Lila.

  16. Dec 2022
    1. The drawers are jammed with jokes typed on 4-by-6-inch cards — 52 drawers, stacked waist-high, like a card catalog of a certain comedian’s life’s work, a library of laughs.

      Joan Rivers had an index card catalog with 52 drawers of 4-by-6-inch index cards containing jokes she'd accumulated over her lifetime of work. She had 18 2 drawer stackable steel files that were common during the mid-1900s. Rather than using paper inserts with the label frames on the card catalogs, she used a tape-based label maker to designate her drawers.

      Scott Currie, who worked with Melissa Rivers on a book about her mother, Joan Rivers, at the comedian’s former Manhattan office. Many of her papers are stored there.Credit...Hiroko Masuike/The New York Times


      Note carefully that the article says 52 drawers, but the image in the article shows a portion of what can be surmised to be 18 2-drawer cabinets for a total of 36 drawers. (14 2-drawer cabinets are pictured, but based on size and perspective, there's one row of 4 2-drawer boxes not shown.)

    1. https://www.youtube.com/watch?v=b-Wp0sLpnMY

      PVA Glue used in bookbinding, but isn't inexpensive.

      • Tacky glue - okay
      • rubber cement - not great
      • elmer's glue - not great, tears esp. for 2 layers
      • Mod podge - pulls nicely and strong
      • mod podge hard shell - cracks, not great
      • PVA Glue - the best of the group

      Recommendations in order: PVA, Tacky Glue, Mod Podge (regular)

      Brush on top edge and do two coats. Don't get it down between sheets.

  17. Nov 2022
    1. https://www.instagram.com/p/CeWV6xBuZUN/?hl=en

      Ryan Holiday in the past has made custom 4 x 6" index cards for taking notes for his individual projects.

      Pictured: A custom slip with 11 light gray lines, small margins all around, and at the top the printed words: "Courage. Temperance. Justice. Wisdom."

      <small><cite class='h-cite via'> <span class='p-author h-card'>Billy Oppenheimer, research assistant to Ryan Holiday</span> in The Notecard System: Capture, Organize, and Use Everything You Read, Watch, and Listen To - Billy Oppenheimer (<time class='dt-published'>11/03/2022 16:53:44</time>)</cite></small>

      <div style="padding:16px;"> <div style=" display: flex; flex-direction: row; align-items: center;"> <div style="background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 40px; margin-right: 14px; width: 40px;"></div> <div style="display: flex; flex-direction: column; flex-grow: 1; justify-content: center;"> <div style=" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; margin-bottom: 6px; width: 100px;"></div> <div style=" background-color: #F4F4F4; border-radius: 4px; flex-grow: 0; height: 14px; width: 60px;"></div></div></div><div style="padding: 19% 0;"></div> <div style="display:block; height:50px; margin:0 auto 12px; width:50px;"><svg width="50px" height="50px" viewBox="0 0 60 60" version="1.1" xmlns="https://www.w3.org/2000/svg" xmlns:xlink="https://www.w3.org/1999/xlink"><g stroke="none" stroke-width="1" fill="none" fill-rule="evenodd"><g transform="translate(-511.000000, -20.000000)" fill="#000000"><g><path d="M556.869,30.41 C554.814,30.41 553.148,32.076 553.148,34.131 C553.148,36.186 554.814,37.852 556.869,37.852 C558.924,37.852 560.59,36.186 560.59,34.131 C560.59,32.076 558.924,30.41 556.869,30.41 M541,60.657 C535.114,60.657 530.342,55.887 530.342,50 C530.342,44.114 535.114,39.342 541,39.342 C546.887,39.342 551.658,44.114 551.658,50 C551.658,55.887 546.887,60.657 541,60.657 M541,33.886 C532.1,33.886 524.886,41.1 524.886,50 C524.886,58.899 532.1,66.113 541,66.113 C549.9,66.113 557.115,58.899 557.115,50 C557.115,41.1 549.9,33.886 541,33.886 M565.378,62.101 C565.244,65.022 564.756,66.606 564.346,67.663 C563.803,69.06 563.154,70.057 562.106,71.106 C561.058,72.155 560.06,72.803 558.662,73.347 C557.607,73.757 556.021,74.244 553.102,74.378 C549.944,74.521 548.997,74.552 541,74.552 C533.003,74.552 532.056,74.521 528.898,74.378 C525.979,74.244 524.393,73.757 523.338,73.347 C521.94,72.803 520.942,72.155 519.894,71.106 C518.846,70.057 518.197,69.06 517.654,67.663 C517.244,66.606 516.755,65.022 516.623,62.101 C516.479,58.943 516.448,57.996 516.448,50 C516.448,42.003 516.479,41.056 516.623,37.899 C516.755,34.978 517.244,33.391 517.654,32.338 C518.197,30.938 518.846,29.942 519.894,28.894 C520.942,27.846 521.94,27.196 523.338,26.654 C524.393,26.244 525.979,25.756 528.898,25.623 C532.057,25.479 533.004,25.448 541,25.448 C548.997,25.448 549.943,25.479 553.102,25.623 C556.021,25.756 557.607,26.244 558.662,26.654 C560.06,27.196 561.058,27.846 562.106,28.894 C563.154,29.942 563.803,30.938 564.346,32.338 C564.756,33.391 565.244,34.978 565.378,37.899 C565.522,41.056 565.552,42.003 565.552,50 C565.552,57.996 565.522,58.943 565.378,62.101 M570.82,37.631 C570.674,34.438 570.167,32.258 569.425,30.349 C568.659,28.377 567.633,26.702 565.965,25.035 C564.297,23.368 562.623,22.342 560.652,21.575 C558.743,20.834 556.562,20.326 553.369,20.18 C550.169,20.033 549.148,20 541,20 C532.853,20 531.831,20.033 528.631,20.18 C525.438,20.326 523.257,20.834 521.349,21.575 C519.376,22.342 517.703,23.368 516.035,25.035 C514.368,26.702 513.342,28.377 512.574,30.349 C511.834,32.258 511.326,34.438 511.181,37.631 C511.035,40.831 511,41.851 511,50 C511,58.147 511.035,59.17 511.181,62.369 C511.326,65.562 511.834,67.743 512.574,69.651 C513.342,71.625 514.368,73.296 516.035,74.965 C517.703,76.634 519.376,77.658 521.349,78.425 C523.257,79.167 525.438,79.673 528.631,79.82 C531.831,79.965 532.853,80.001 541,80.001 C549.148,80.001 550.169,79.965 553.369,79.82 C556.562,79.673 558.743,79.167 560.652,78.425 C562.623,77.658 564.297,76.634 565.965,74.965 C567.633,73.296 568.659,71.625 569.425,69.651 C570.167,67.743 570.674,65.562 570.82,62.369 C570.966,59.17 571,58.147 571,50 C571,41.851 570.966,40.831 570.82,37.631"></path></g></g></g></svg></div><div style="padding-top: 8px;"> <div style=" color:#3897f0; font-family:Arial,sans-serif; font-size:14px; font-style:normal; font-weight:550; line-height:18px;">View this post on Instagram</div></div><div style="padding: 12.5% 0;"></div> <div style="display: flex; flex-direction: row; margin-bottom: 14px; align-items: center;"><div> <div style="background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(0px) translateY(7px);"></div> <div style="background-color: #F4F4F4; height: 12.5px; transform: rotate(-45deg) translateX(3px) translateY(1px); width: 12.5px; flex-grow: 0; margin-right: 14px; margin-left: 2px;"></div> <div style="background-color: #F4F4F4; border-radius: 50%; height: 12.5px; width: 12.5px; transform: translateX(9px) translateY(-18px);"></div></div><div style="margin-left: 8px;"> <div style=" background-color: #F4F4F4; border-radius: 50%; flex-grow: 0; height: 20px; width: 20px;"></div> <div style=" width: 0; height: 0; border-top: 2px solid transparent; border-left: 6px solid #f4f4f4; border-bottom: 2px solid transparent; 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      A post shared by Ryan Holiday (@ryanholiday)

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      I used to do this sort of practice before, but I used buckslips instead.

  18. Oct 2022
    1. This effort, which Americans have supported almostfrom the beginning of the national existence and which is oneof the cornerstones of our democratic way of life, has hadremarkable results.

      Read in juxtaposition with the knowledge of orality and along with Graeber & Wengrow's The Dawn of Everything, one could certainly argue that there are other ways of knowing which provide potentially better pathways to democracy.

      Further, the simple fact of basic literacy doesn't necessarily encourage democracy. Take a look at the January 6th (2021) insurrectionists who were likely broadly literate, but who acted more like a damaged oral society and actively subverted democracy.

      Literacy plus "other things" are certainly necessary for democracy. How do we define these other things, and then once we have, is literacy still part of the equation for democracy?

    1. Dwyer, Edward J. “File Card Efficiency.” Journal of Reading 26, no. 2 (1982): 171–171.

      Ease of use in writing and grading with short assignments by using 4 x 6" index cards in classrooms.

      This sounds like some of the articles from 1912 and 1917 about efficiency of card indexes for teaching.

      I'm reminded of some programmed learning texts that were card-based (or really strip-based since they were published in book form) in the 1960s and 1970s. Thse books had small strips with lessons or questions on the front with the answers on the reverse. One would read in strips through the book from front to back and then start the book all over again on page one on the second row of strips and so on.

  19. Sep 2022
    1. Posted byu/jackbaty4 hours agoCard sizes .t3_xib133._2FCtq-QzlfuN-SwVMUZMM3 { --postTitle-VisitedLinkColor: #9b9b9b; --postTitleLink-VisitedLinkColor: #9b9b9b; --postBodyLink-VisitedLinkColor: #989898; } I've been on-again/off-again with paper for PKM, but one thing remains consistent each time: I don't enjoy using 4x6 index cards. I much prefer 3x5-inch cards. I realize that it's irrational, but there it is.My question is if I dive into building an antinet, will I regret using 3x5 cards? I already have hundreds of them. I have dividers, holders, and storage boxes for them. I just prefer how they _feel_, as weird as that sounds.I'd like to hear if people are using 3x5 cards successfully or if you've come to regret it.

      While it may be slightly more difficult to find larger metal/wood cases for the 4x6 or 5x8 cards, it's a minor nuisance and anyone who wants them will eventually find the right thing for them. Beyond this, choose the card size that feels right to you.

      If you don't have an idea of what you need or like, try things out for 10-20 cards and see how it works for you, your handwriting size, and general needs. People have been using 3x5, 4x6, and even larger for hundreds of years without complaining about any major issues. If Carl Linnaeus managed to be okay with 3x5, which he hand cut by the way, I suspect you'll manage too.

      Of course I won't mention to the Americans the cleverness of the A6, A5, A4 paper standards which allows you to fold the larger sizes in half to get the exact next smaller size down. Then you might get the benefit of the smaller size as well as the larger which could be folded into your collection of smaller cards, you just have to watch out for accidentally wrapping ("taco-ing") a smaller card inside of a larger one and losing it. I suppose you could hand cut your own 5" x 6" larger cards to do this if you found that you occasionally needed them.

      For the pocketbook conscious, 3x5 does have the benefit of lower cost as well as many more options and flexibility than larger sizes.

      At least commercial card sizes are now largely standardized, so you don't have deal with changing sizes the way Roland Barthes did over his lifetime.

      My personal experience and a long history of so many manuals on the topic saying "cards of the same size" indicates that you assuredly won't have fun mixing different sized slips together. I personally use 3x5" cards in a waste book sense, but my main/permanent collection is in 4x6" format. Sometimes I think I should have done 3 x 5, but it's more like jealousy than regret, particularly when it comes to the potential of a restored fine furniture card catalog. But then again...

    1. Art

      Tracy and I would've been more interested in seeing more depictions of the negative aspects of religion which weren't addressed enough. A good example of this would've been possibly the Salem Witch Trials and the Last Judgement.

  20. Aug 2022
    1. Forcertainlyagreatervarietyofcards,clippings,andsuchlikecan befiledbehind 4x6slipsthan behind3x5's.

      A benefit of 4 x 6" cards is that clippings and other items can often be more easily filed along with them as opposed to the smaller 3 x 5" cards.

    2. shall I adopt the 3x5 slip or the 4x61

      Dow indicates in 1924 that 3 x 5" and 4 x 6" are both commonly had in a range of materials the US as well as boxes or cases to keep them in. He does mention that one can also cut their own paper, indicating that this is a possibility.

    1. Citation: Kirkpatrick, Keith. The Road to 6G. Communications of the ACM, September 2022, Vol. 65 No. 9, Pages 14-16 10.1145/3546959

      Although it is early in the commercial rollout of 5G mobile networks, countries, companies and standards bodies are gearing up for what will be in the next version—so called “6G” mobile network. There are already experimental allocation of high frequency radio bands and testing that has occurred at about 100m distances. The high frequency will mean higher bandwidth, but over shorter distances. There are experiments to make passive graphene reflectors on common surfaces to help with propagation. What may come is a convergence of 6G with WiFi 6 to support connectivity from body-area networks to low earth orbit satellites.

  21. Jul 2022
    1. So in total, Bannon predicted Trump’s premature victory declaration, which came true. He predicted that all hell would break loose on Jan. 6, which came true. He predicted that uncertainty about election results spurred by a bunch of lawsuits would force Congress to decide the election, which wound up essentially being Trump’s plan. And he suggested that unrest was perhaps desirable and/or could be of some utility in all of this, which evidence suggests Trump might well have agreed with on Jan. 6.

      Did he just predict or was he tactically planning this?

    1. the question you were asking was what is mind or consciousness so here we're using the words synonymously um and from a buddhist perspective uh there are 01:11:50 six what we call primary minds and then there's a whole slew of secondary minds and some of the more common systems include 51 in the secondary minds now please understand that mind like 01:12:04 everything else that exists in the world doesn't exist permanently it exists there are a few exceptions okay but essentially everything that exists in the world um is not permanent therefore 01:12:18 it's changing moment to moment therefore everything exists as a continuum including mind so that means there'll be a moment of mind followed by a next moment of mind etc 01:12:31 and the next moment of mind is determined primarily but not solely by the previous moment of mind so from that we can extrapolate a continuum an infinite continuum and mind is an 01:12:43 infinite continuum from perspective of buddhism and that means that we've had that implies suggests rebirth and it suggests we've had ultimate we've had infinite rebirths there's been no beginning 01:12:56 and so this then comes up again with the notion of a beginning creator if you will a so-called you know god there are some some problems here to resolve this um 01:13:07 and so mind is a continuum it's infinite now each moment of mind is made up of a primary mind and a constellation of secondary minds these six primary or the five as you read from nagarjuna the five 01:13:22 sensory minds of seeing hearing smelling tasting touching tactile right these five plus what's sometimes called the mental consciousness and that has live different levels of subtlety on the 01:13:34 grossest level is thinking if we go a little bit deeper a little bit more so little subtler we have dream mind which seems like these senses are active but actually 01:13:46 when we're sleeping the senses are inactive so it's just something coming from our sixth or mental consciousness it seems like the senses are active in dream mind that dream mind is a little more subtle than a wake mind awake 01:13:59 thinking mind and then if we go more subtle we're talking now again about awake mind we we talk about intuition when we're in intuition we're not thinking right it's a non-conceptual 01:14:11 mind uh in that sense and deeper yet our minds we call non-conceptual and non-dual where there's no awareness of a subject or an object so subject object non-duality so 01:14:25 that's kind of the rough sort of you know lay of the land

      Barry provides a brief summary of what the word "mind" means from a Buddhist philosophy perspective and says that there are six primary minds and 51 secondary minds.

      The 6 primary minds are the 5 senses plus mental consciousness, which itself consists of the coarse thinking (conceptual) mind, the intuitive mind (these two could be roughly mapped to Daniel Kahnaman's fast and slow system respectively), as well as the dreaming mind.

      Barry also conveys an interpretation of reincarnation based on the concept that the mind is never the same from one moment to the next, but is rather an ever changing continuum. The current experience of mind is GENERALLY most strongly influenced by the previous moments but also influenced by temporally distant memories. This above interpretation of reincarnation makes sense, as the consciousness is born anew in every moment. It is also aligned to the nature of the Indyweb interpersonal computing ecosystem, in which access to one's own private data store, the so-called Indyhub, allows one to experience the flow of consciousness by seeing how one's digital experience, which is quite significant today, affects learning on a moment to moment basis. In other words, we can see, on a granular level, how one idea, feeling or experience influences another idea, experience or feeling.

    1. the six 00:48:41 six big systems i've mentioned can be viewed as a cognitive architecture it's the it's the means by which the society learns decides adapts and 00:48:54 and this society's efforts this is the third underlying position the society's efforts to learn decide and adapt and be viewed as being driven by an intrinsic purpose and that's really key also 00:49:08 because it's not just that we're learning deciding and adapting willy-nilly i mean i mean maybe it seems that way in the world you know in the sense we're so dysfunctional it kind of is billy nilly but 00:49:20 but what really matters is that we learn decide and adapt in relation to whatever intrinsic purpose we actually have as as a society as individuals in a 00:49:34 society it's that it's it's it's it's as i will use the the term uh maybe several times today it's solving problems that matter that really that really 00:49:45 matter that's what we're after

      Second Proposition: The six thrusts or prmary societal systems are the cognitive architecture of the superorganism which it uses to sense the world

  22. Jun 2022
  23. heathercoxrichardson.substack.com heathercoxrichardson.substack.com
    1. at the end of the hearing that witnesses said they had been pressured by Trump’s people to remain “loyal” when testifying, and having just tipped their hand about just how much information the committee has, Thompson urged those witnesses to come back and revise their testimony.

      Witness tampering here. Waiting for more to come out of the woodwork.

    2. “You heard it, Pat. He thinks Pence deserves it. He doesn’t think they’re doing anything wrong.”

      This is so sophmoric. It reminds me of the mean kids in high school.

    3. The president is only supposed to go into the House chamber when specifically invited

      British Parliamentary rules prohibit monarch from Parliament without an invitaion. Possibly modeled on this practice. Remember Trump's disinvitation from the House for his last state of the union, which he had to give from the WH.

    4. Hutchinson connected Trump to the insurrection attempt

      To Stone, Flynn and the Oath Keepers, via Meadows.

    1. RRID:ZFIN_ZDB-ALT-150113-6

      DOI: 10.7554/eLife.76640

      Resource: (ZFIN Cat# ZDB-ALT-150113-6,RRID:ZFIN_ZDB-ALT-150113-6)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-ALT-150113-6


      What is this?

  24. Apr 2022
    1. Amsell A. Colebrooke was married to Gertrude Flora (Pohelman) Colebrooke born May 31,1891 - death Sept. 25, 1978 He left her with 6 small children, (around 1922 or 1923, and never came back, all assumed he was dead, until photos and named surfaced) 1- Shirley A 2- Amsell A Jr 3- Larkland P 4- Delores A 5- Frederick D 6- Gertude just a baby, to be at Nancy Cunard’s side The mom Gertude struggled to raise them on her own, she only knew some English, as she spoke fluent German.

  25. Mar 2022
    1. In this ancient text, we can see that El and Yahweh were still perceived as being two separate deities, with Yahweh subordinate to El. But as time went by, El and Yahweh became conflated: the two deities began to be seen as one and the same.In Exodus 6:3 God tells Moses: "I appeared unto Abraham, unto Isaac, and unto Jacob, by the name of God Almighty (El Elyon), but by my name Jehovah was I not known to them." Thus the ancients only knew God as El, but as time went by they discovered that El was just another name of Yahweh.

      In Deuteronomy 32 the gods El and Yahweh are separate deities which, over time, became conflated into one god as indicated in Exodus 6:3.

  26. Jan 2022
    1. e tourisme de croisière

      Arg6: le tourisme de croisière reste un enjeu économique majeur

      • Un secteur en essor 2019 - 30M de personnes croisière Caraïbes, Mer Méditerranée, Asie Pacifique

      • Qui est marqué par une forte concurrence et de lours freins Multinationales: Carnival, Royal Caribbean, MSC Emissions CO2, risques accidents + COVID19: mauvaise réputation

    1. India was the highest (5.8 times) and only Chile (5.7 times) came close.
    2. Excess deaths analyses based on deaths registered in the Civil Registration System (CRS) have shown that they have been as high as six times the official death toll for just 11 States and Union Territories (Maharashtra, Punjab, West Bengal, Tamil Nadu, Kerala, Karnataka, Himachal Pradesh, Haryana, Delhi, Madhya Pradesh and Andhra Pradesh) for which such data was available.
      • =>
    1. TMDB (82%) JustWatch (90%) filmstarts.de (4,5/5) moviepilot.de (8/10) IMDB (8,3/10 · 114K · Metascore: 88)

      Der unabhängige Anthony (Anthony Hopkins) lehnt auch im Alter und zunehmend von Demenz geplagt jegliche Hilfe von seiner Tochter Anne (Olivia Colman) ab. Diese Hilfe wird aber unabdingbar, als Anne beschließt, mit ihrem Mann Paul (Rufus Sewell) nach Paris zu ziehen, und Anthony somit allein in der Wohnung zurückbleiben müsste, in der Anne und Paul mit ihm leben. Dass das nicht funktionieren wird, wird schon daran deutlich, dass Anthony immer wieder sehr durcheinanderkommt. Er wundert sich etwa über den unbekannten Mann (Mark Gatiss), der auf einmal im Wohnzimmer sitzt und behauptet, sein Schwiegersohn Paul zu sein. Und selbst die Frau (Olivia Williams), die kurz darauf nach Hause kommt und behauptet seine Tochter Anne zu sein, erkennt er nicht. Die Pflegerin Laura (Imogen Poots) soll Anthony helfen, doch auch wenn er sich anfangs charmant gibt: Er hat bereits zuvor andere Pflegerinnen mit seinen Stimmungsschwankungen vergrault... filmstarts.de

      Mit „The Father“ gelingt Florian Zeller eine herausragende Adaption seines eigenen Bühnenstücks. Ganz großes Kino! [filmstarts.de] (https://www.filmstarts.de/kritiken/273981/kritik.html) 4,5/5

      „The Father“ zeigt aus der Sicht eines 80-Jährigen, wie sich die Wahrnehmung der Welt aufgrund von Demenz verändern kann. Das Ergebnis ist ein eindrucksvolles, ungewöhnliches und herausragend gespieltes Drama, das mit einfachsten Mitteln ein Entfremdungsgefühl entstehen lässt und verdeutlicht, was es heißt, in der Welt verloren zu gehen. Oliver Armknecht 9/10

    1. moviepilot.de 6,1/10 IMDB 5,8/10 · 150

      Muskelpaket und Einzelgänger Mosk (Thomas Sarbacher) hat alles andere als diesen süßen Labradorwelpen im Kopf: Er trainiert seit Wochen hart für die anstehenden gefängnisinternen Meisterschaften im Gewichtheben. So sträubt er sich zunächst auch vehement gegen das Projekt der neuen Gefängnisdirektorin Gloria (Clelia Sarto), bei dem ausgewählte Häftlinge Welpen zu Blindenhunden ausbilden sollen. Leider hilft weder sein abweisendes Verhalten noch ein klares „Nein“, er wird gegen seinen Willen für das Programm ausgewählt und zieht kurz darauf zusammen mit fünf weiteren Teilnehmern und Knastkumpanen in einen speziellen Trakt der Vollzugsanstalt. filmstarts.de 3,5/5

      Ein Häftling findet sich gegen seinen Willen in einem Pilotprojekt wieder, bei dem er und fünf Mitgefangene Welpen zu Blindenhunden ausbilden. Unterhaltsamer Gefängnisfilm, der die Klischees des Genres umschifft. epdFilm 6/10

    1. moviepilot.de 6,3/10 IMDB 5,7/10 · 210

      Es war einmal vor langer Zeit in den endlosen Weiten des Atlasgebirges. Der Nomade Mustapha soll die besten arabischen Vollblüter und Reiter seines Stammes nach Marrakesch führen, um am ruhmreichsten aller Pferderennen teilzunehmen: dem Agdal. Aber bevor es in die Berge geht, holt er in der Stadt seine elfjährige Tochter, ein menschenscheues Mädchen mit dem Namen Zaina, von deren Existenz er erst beim Tod von Zainas Mutter erfahren hat. Denn einst musste Mustapha unter dem Druck seines Stammes diese Frau verstoßen, weil sie als Mann verkleidet an dem Agdal teilgenommen hatte. filmstarts.de (2,5/5)

  27. Dec 2021
    1. painted an American flag on his bare chest, but painted it upside down.

      this didn't happen. in front of Dallas city hall Johnson unfurled the American flag, doused it with kerosene and set it on fire. as the flag burned protestors were chanting "red white and blue we spit on you"

  28. Nov 2021
    1. https://thedispatch.com/p/a-note-to-our-readers-from-steve

      Center-right journalists Steve Hayes and Jonah Goldberg of The Dispatch have severed ties with Fox News over a misinformation campaign from Tucker Carlson based on the January 6 events.

      Kudos to them for drawing a line on this issue.

    1. El factor tiempo de trabajo está también muy relacionado con la variabilidad de la presión de inyección, ya que a medida que incrementa el tiempo de operación de un motor, se incrementa el desgaste de las piezas, siendo agravado el sistema de alimentación por la variación de la calidad del combustible

      También depende del factor de cuanto uso se le ha dado a ese motor, no solo por el incremento de desgaste significa que va a bajar su calidad.

    1. 10 percent of the private schools available were religious

      incorrect- 80% of the private schools were religious

  29. Oct 2021
    1. “Hurry up and do it before someone else does!” she told him. And so he did.

      At least he did it quickly as possible because it's a known fact that people can have similar ideas as you.

      article

    1. ephemera

      Definition of ephemera 1: something of no lasting significance —usually used in plural

      2 ephemera plural : paper items (such as posters, broadsides, and tickets) that were originally meant to be discarded after use but have since become collectibles

      merriam webster

    2. A handful of African-American designers seemed exempt from Modernism’s influence, which may be because they didn’t work in advertising or commerce.

      This is not surprising at all. Funny thing is just as he mentioned that...it made me realize there's barely any black designers being known, especially around that time.

    1. Congress has clearly chosen to rid itself of that power and give it to the president.

      This is not true. Congress has not lost its authority to be the lawmaker.

  30. Sep 2021
    1. ZFIN: ZDB-ALT-120419-6

      DOI: 10.1016/j.devcel.2021.09.005

      Resource: (ZFIN Cat# ZDB-ALT-120419-6,RRID:ZFIN_ZDB-ALT-120419-6)

      Curator: @Naa003

      SciCrunch record: RRID:ZFIN_ZDB-ALT-120419-6


      What is this?

    2. ZFIN: ZDB-ALT-051223-6

      DOI: 10.1016/j.devcel.2021.09.005

      Resource: (ZFIN Cat# ZDB-ALT-051223-6,RRID:ZFIN_ZDB-ALT-051223-6)

      Curator: @Naa003

      SciCrunch record: RRID:ZFIN_ZDB-ALT-051223-6


      What is this?

  31. Aug 2021
    1. RRID:ZFIN_ZDB-ALT-051223-6

      DOI: 10.7554/eLife.42881

      Resource: (ZFIN Cat# ZDB-ALT-051223-6,RRID:ZFIN_ZDB-ALT-051223-6)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-ALT-051223-6


      What is this?

    1. RRID:ZFIN_ZDB-GENO-090918-6

      DOI: 10.1002/cne.23645

      Resource: (ZFIN Cat# ZDB-GENO-090918-6,RRID:ZFIN_ZDB-GENO-090918-6)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-GENO-090918-6


      What is this?

  32. Jul 2021
    1. Zebrafish: npas4ls5 mutant

      DOI: 10.1016/j.celrep.2019.05.052

      Resource: (ZFIN Cat# ZDB-ALT-010426-6,RRID:ZFIN_ZDB-ALT-010426-6)

      Curator: @ethanbadger

      SciCrunch record: RRID:ZFIN_ZDB-ALT-010426-6


      What is this?

    1. RRID:ZDB-ALT-040217-6

      DOI: 10.7554/eLife.37001

      Resource: (ZFIN Cat# ZDB-ALT-040217-6,RRID:ZFIN_ZDB-ALT-040217-6)

      Curator: @evieth

      SciCrunch record: RRID:ZFIN_ZDB-ALT-040217-6


      What is this?

    2. RRID:ZDB-ALT-110310-6

      DOI: 10.7554/eLife.37001

      Resource: (ZFIN Cat# ZDB-ALT-110310-6,RRID:ZFIN_ZDB-ALT-110310-6)

      Curator: @evieth

      SciCrunch record: RRID:ZFIN_ZDB-ALT-110310-6


      What is this?

  33. Jun 2021
    1. ZFIN: ZDB-ALT-131127-6

      DOI: 10.1016/j.cub.2021.05.042

      Resource: (ZFIN Cat# ZDB-ALT-131127-6,RRID:ZFIN_ZDB-ALT-131127-6)

      Curator: @Naa003

      SciCrunch record: RRID:ZFIN_ZDB-ALT-131127-6


      What is this?

    2. ZFIN: ZDB-ALT-110217-6

      DOI: 10.1016/j.cub.2021.05.042

      Resource: (ZFIN Cat# ZDB-ALT-110217-6,RRID:ZFIN_ZDB-ALT-110217-6)

      Curator: @Naa003

      SciCrunch record: RRID:ZFIN_ZDB-ALT-110217-6


      What is this?

  34. May 2021
    1. ZFIN: ZDB-ALT-051111-6

      DOI: 10.1016/j.devcel.2020.07.015

      Resource: (ZFIN Cat# ZDB-ALT-051111-6,RRID:ZFIN_ZDB-ALT-051111-6)

      Curator: @Naa003

      SciCrunch record: RRID:ZFIN_ZDB-ALT-051111-6


      What is this?

    2. ZFIN: ZDB-ALT-051223-6

      DOI: 10.1016/j.devcel.2020.07.015

      Resource: (ZFIN Cat# ZDB-ALT-051223-6,RRID:ZFIN_ZDB-ALT-051223-6)

      Curator: @Naa003

      SciCrunch record: RRID:ZFIN_ZDB-ALT-051223-6


      What is this?

    3. ZFIN: ZDB-GENO-200316-6

      DOI: 10.1016/j.devcel.2020.07.015

      Resource: (ZFIN Cat# ZDB-GENO-200316-6,RRID:ZFIN_ZDB-GENO-200316-6)

      Curator: @Naa003

      SciCrunch record: RRID:ZFIN_ZDB-GENO-200316-6


      What is this?

  35. Mar 2021
    1. CONSEQUENCES JURIDIQUES DU DEFAUT D’ACCUSE DE RECEPTION. Article L112-6 CRPASi l’administration n’accuse pas réception de la demande, ou le fait demanière incorrecte (mentions incomplètes ou erronées), les délais derecours ne sont pas opposables à l’auteur de la demande.L’usager pourra donc contester votre décision implicite à tout momentdevant la juridiction administrative.Il est donc important pour la sécurité juridique de vos décisions, derespecter les règles tant sur la forme que sur le fond.
    1. Results for individual PALB2 variants were normalized relative to WT-PALB2 and the p.Tyr551ter (p.Y551X) truncating variant on a 1:5 scale with the fold change in GFP-positive cells for WT set at 5.0 and fold change GFP-positive cells for p.Y551X set at 1.0. The p.L24S (c.71T>C), p.L35P (c.104T>C), p.I944N (c.2831T>A), and p.L1070P (c.3209T>C) variants and all protein-truncating frame-shift and deletion variants tested were deficient in HDR activity, with normalized fold change <2.0 (approximately 40% activity) (Fig. 1a).

      AssayResult: 4.7

      AssayResultAssertion: Normal

      StandardErrorMean: 0.32

    2. A total of 84 PALB2 patient-derived missense variants reported in ClinVar, COSMIC, and the PALB2 LOVD database were selected

      HGVS: NM_024675.3:c.109C>T p.(Arg37Cys)

    1. SUPPLEMENTARY DATA

      AssayResult: 93.06

      AssayResultAssertion: Not reported

      PValue: > 0.9999

      Comment: Exact values reported in Table S3.

    2. To this end, 44 missense variants found in breast cancer patients were identified in the ClinVar database (https://www.ncbi.nlm.nih.gov/clinvar) and/or selected by literature curation based on their frequency of description or amino acid substitution position in the protein (Supplemental Table S1).

      HGVS: NM_024675.3:c.226A>G p.(Ile76Val)

    1. Source Data

      AssayResult: 17.43

      AssayResultAssertion: Abnormal

      ReplicateCount: 2

      StandardErrorMean: 5.19

      Comment: Exact values reported in “Source Data” file.

    2. Source Data

      AssayResult: 7.82

      AssayResultAssertion: Abnormal

      ReplicateCount: 2

      StandardDeviation: 2.31

      StandardErrorMean: 1.64

      Comment: Exact values reported in “Source Data” file.

    3. We, therefore, analyzed the effect of 48 PALB2 VUS (Fig. 2a, blue) and one synthetic missense variant (p.A1025R) (Fig. 2a, purple)29 on PALB2 function in HR.

      HGVS: NM_024675.3:c.1227_1231delTGTTA p.(Y409X)

    1. Most Suspected Brugada Syndrome Variants Had (Partial) Loss of Function

      AssayResult: 0

      AssayResultAssertion: Abnormal

      ReplicateCount: 39

      StandardErrorMean: 0

      Comment: This variant had loss of function of peak current (<10% of wildtype), therefore it was considered abnormal (in vitro features consistent with Brugada Syndrome Type 1). (Personal communication: A. Glazer)

    2. we selected 73 previously unstudied variants: 63 suspected Brugada syndrome variants and 10 suspected benign variants

      HGVS: NM_198056.2:c.1100G>T p.(Arg367Leu)

  36. Feb 2021
    1. RRID:ZFIN_ZDB-ALT-160322-6

      DOI: 10.1111/bph.15156

      Resource: (ZFIN Cat# ZDB-ALT-160322-6,RRID:ZFIN_ZDB-ALT-160322-6)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-ALT-160322-6


      What is this?

    1. RRID:ZDB-ALT-040217-6

      DOI: 10.7554/eLife.37001

      Resource: (ZFIN Cat# ZDB-ALT-040217-6,RRID:ZFIN_ZDB-ALT-040217-6)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-ALT-040217-6


      What is this?

    2. RRID:ZDB-ALT-110310-6

      DOI: 10.7554/eLife.37001

      Resource: (ZFIN Cat# ZDB-ALT-110310-6,RRID:ZFIN_ZDB-ALT-110310-6)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-ALT-110310-6


      What is this?

    1. RRID:ZFIN_ZDB-ALT-051223-6

      DOI: 10.7554/eLife.42881

      Resource: (ZFIN Cat# ZDB-ALT-051223-6,RRID:ZFIN_ZDB-ALT-051223-6)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-ALT-051223-6


      What is this?

    2. RRID:ZFIN_ZDB-ALT-160323-6

      DOI: 10.7554/eLife.42881

      Resource: (ZFIN Cat# ZDB-ALT-160323-6,RRID:ZFIN_ZDB-ALT-160323-6)

      Curator: @scibot

      SciCrunch record: RRID:ZFIN_ZDB-ALT-160323-6


      What is this?

    1. Supplemental material

      AssayResult: 89, 90

      AssayResultAssertion: Normal

      Comment: See Table S3 for details

    2. Supplemental material

      AssayResult: 5.8, 6.1

      AssayResultAssertion: Abnormal

      Comment: See Table S3 for details

    3. We analysed a total of 82 blood samples derived from 77 individuals (online supplemental table 3). These 77 individuals corresponded either to new index cases suspected to harbour a pathogenic TP53 variant or to relatives of index cases harbouring TP53 variants.

      HGVS: NM_000546.5:c.1043T>C p.(Leu348Ser)

  37. Jan 2021
    1. PTT

      AQ:6 Please provide an expansion for PTT.

      PTT: partial thromboplastin time

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  38. Oct 2020