1,084 Matching Annotations
  1. Jul 2022
  2. bafybeiac2nvojjb56tfpqsi44jhpartgxychh5djt4g4l4m4yo263plqau.ipfs.dweb.link bafybeiac2nvojjb56tfpqsi44jhpartgxychh5djt4g4l4m4yo263plqau.ipfs.dweb.link
    The%20Human%20Takeover%20-%20A%20Call%20for%20a%20Venture%20into%20an%20Existential%20Opportunity%20-%20lenartowicz2018.pdf
    1
    1. stopresetgo 23 Jul 2022
      FollowingSimondon’s social theory [37] and our previous work [10 ], social systems are themselves individualsthat harbour in them preindividual forces of transformation. Therefore we do not see in the currentorganization of personhood, inasmuch as it seems unassailable, a final unchangeable state of affairs.

      !- references : evolutionary biology * Evolutionary biologists have developed similar ideas to explain how throughout history, groups of individual organisms that clustered together and discovered better fitness as a result of symbiotic relationships began to reproduce as a whole new entity. Hence the collective became the new individual * Robin et al. paper: https://hyp.is/go?url=https%3A%2F%2Fwww.frontiersin.org%2Farticles%2F10.3389%2Ffevo.2021.711556%2Ffull&group=world * Robin et al. video presentation: https://hyp.is/go?url=http%3A%2F%2Fdocdrop.org%2Fvideo%2F6J-J72GoqhY%2F&group=world * Stuart West video: https://hyp.is/go?url=http%3A%2F%2Fdocdrop.org%2Fvideo%2FVUfNEHl44hc%2F&group=world

      Stuart West Amanda Robin Major Evolutionary Transition MET evolutionary biology
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    bafybeiac2nvojjb56tfpqsi44jhpartgxychh5djt4g4l4m4yo263plqau.ipfs.dweb.link/The Human Takeover - A Call for a Venture into an Existential Opportunity - lenartowicz2018.pdf
  3. www.biorxiv.org www.biorxiv.org
    LncRNA RUS shapes the gene expression program towards neurogenesis
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    biorxiv.org/content/10.1101/2022.02.17.480853v1
  4. Jun 2022
  5. www.biorxiv.org www.biorxiv.org
    Negative curvature-promoting lipids instruct nuclear ingression of low autophagic potential vacuoles
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    biorxiv.org/content/10.1101/2021.06.26.450031v1
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    Genetic and compound screens uncover factors modulating cancer cell response to indisulam
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    biorxiv.org/content/10.1101/2021.12.20.473451v1
  7. www.scientificamerican.com www.scientificamerican.com
    The Complicated Legacy of E. O. Wilson
    2
    1. chrisaldrich 01 Jun 2022

      https://www.scientificamerican.com/article/the-complicated-legacy-of-e-o-wilson/

      I can see why there's so much backlash on this piece.

      It could and should easily have been written without any reference at all to E. O. Wilson and been broadly interesting and true. However given the editorial headline "The Complicated Legacy of E. O. Wilson", the recency of his death, and the photo at the top, it becomes clickbait for something wholly other.

      There is only passing reference to Wilson and any of his work and no citations whatsoever about who he was or why his work was supposedly controversial. Instead the author leans in on the the idea of the biology being the problem instead of the application of biology to early anthropology which dramatically mis-read the biology and misapplied it for the past century and a half to bolster racist ideas and policies.

      The author indicates that we should be better with "citational practices when using or reporting on problematic work", but wholly forgets to apply it to her own writing in this very piece.

      I'm aware that the magazine editors are most likely the ones that chose the headline and the accompanying photo, but there's a failure here in both editorial and writing for this piece to have appeared in Scientific American in a way as to make it more of a hit piece on Wilson just days after his death. Worse, the backlash of the broadly unsupported criticism of Wilson totally washed out the attention that should have been placed on the meat of the actual argument in the final paragraphs.

      Editorial failed massively on all fronts here.

      This article seems to be a clear example of the following:

      Any time one uses the word "problematic" to describe cultural issues, it can't stand alone without some significant context building and clear arguments about exactly what was problematic and precisely why. Otherwise the exercise is a lot of handwaving and puffery that does neither side of an argument or its intended audiences any good.

      read E. O. Wilson racist ideas evolution biology Scientific American editorial failure editorials health disparities public health
    2. chrisaldrich 01 Jun 2022
      Second, the application of the scientific method matters: what works for ants and other nonhuman species is not always relevant for health and/or human outcomes. For example, the associations of Black people with poor health outcomes, economic disadvantage and reduced life expectancy can be explained by structural racism, yet Blackness or Black culture is frequently cited as the driver of those health disparities. Ant culture is hierarchal and matriarchal, based on human understandings of gender. And the descriptions and importance of ant societies existing as colonies is a component of Wilson’s work that should have been critiqued. Context matters.

      The author is going in two opposite directions here and neither match up. A massive swath of our medicine research is wholly based on translational genetics. (That is, our basic research on organisms like flies (drosophila), worms (C. elegans), zebrafish, mice, rats, primates, etc. is contingent on moving medicines applicable to simpler genetic models in these animals will also work for humans who share large amounts of genetic material as the result of evolutionary dynamics. Sure some of it may not be relevant for humans because of both genetic and epigenetic (environmental) factors, but generally we expect that more will than won't.

      This basic fact is wholly separate from the health disparities issue. While there are some (and few of these are generally scientists in my experience) who believe that culture is the driving factor, there is enough proof to show that structural racism is the driving factor in almost all cases. I'm unaware of any translational genetic work on ant culture into human culture in any of the scientific literature and she certainly doesn't cite any to provide any sort of evidence to the contrary. As a result, she isn't providing any context at all.

      translational medicine genetics biology
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  8. whyevolutionistrue.com whyevolutionistrue.com
    Scientific American does an asinine hit job on E. O. Wilson, calling him a racist
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    whyevolutionistrue.com/2021/12/30/scientific-american-does-an-asinine-hit-job-on-e-o-wilson-calling-him-a-racist/
  9. www.biorxiv.org www.biorxiv.org
    Map7D2 and Map7D1 facilitate microtubule stabilization through distinct mechanisms to control cell motility and neurite outgrowth.
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    biorxiv.org/content/10.1101/2021.10.27.466197v3
  10. www.biorxiv.org www.biorxiv.org
    A RIF1 and KAP1-based, double-bookmarking system generates a toggle switch that stabilises the identities of the active and inactive X chromosomes during random X inactivation in mouse
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    biorxiv.org/content/10.1101/2020.06.04.133512v2
  11. May 2022
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    Diauxic lags explain unexpected coexistence in multi-resource environments
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    biorxiv.org/content/10.1101/2021.08.09.455603v2
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    Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly
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    biorxiv.org/content/10.1101/2021.10.26.465695v2
  14. www.biorxiv.org www.biorxiv.org
    UPF3A and UPF3B are redundant and modular activators of nonsense-mediated mRNA decay in human cells
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    biorxiv.org/content/10.1101/2021.07.07.451444v3
  15. bioregistry.io bioregistry.io
    Bioregistry
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  16. bioportal.lirmm.fr bioportal.lirmm.fr
    Annotator | SIFR BioPortal
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  17. bmcbioinformatics.biomedcentral.com bmcbioinformatics.biomedcentral.com
    SIFR annotator: ontology-based semantic annotation of French biomedical text and clinical notes
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    bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-018-2429-2
  18. github.com github.com
    GitHub - nanotate-tool/nanotate: Nanotate is a free and open source tool. The code behind the tool is available on Github. End-users can install it by creating a bookmark. The documentation about how to install and use the Nanotate is available at http://doi.org/10.5281/zenodo.5101941 A running instance of the tool can be found https://nanotate.bitsfetch.com
    1
    1. kael 10 May 2022
      <details open> <summary>
      Nanotate Annotations Samples
      </summary> ```json [ { "id":"d5JrdABbEeuatj9X3vvoXw", "authority":"__world__", "url":"https://protocolexchange.researchsquare.com/article/pex-1069/v1", "created":"2020-09-27T00:50:41.265044+00:00", "updated":"2020-09-27T00:50:41.265044+00:00", "title":[ "Sample preparation and imaging procedures for fast and multiplexed superresolution microscopy with DNA-PAINT-ERS" ], "refs":[ ], "isReply":false, "isPagenote":false, "user":"acct:miguel.ruano@hypothes.is", "displayName":null, "text":"", "prefix":"for 10 minutes. Wash with PBS3. ", "exact":"Add imaging buffer with desired ratios of Buffer C (500 mM), ethylene carbonate, and IS-CF660R at 1-2 nM final concentration. The exact concentration of IS may need to be adjusted depending on the target and based on the imaging kinetics.", "suffix":"", "start":15158, "end":15396, "tags":[ "step" ], "group":"__world__", "ontologies":[ ] }, { "id":"FrhgjABcEeu5B4dnXgvb_A", "authority":"__world__", "url":"https://protocolexchange.researchsquare.com/article/pex-1069/v1", "created":"2020-09-27T00:55:08.276888+00:00", "updated":"2020-10-05T14:15:00.764415+00:00", "title":[ "Sample preparation and imaging procedures for fast and multiplexed superresolution microscopy with DNA-PAINT-ERS" ], "refs":[ ], "isReply":false, "isPagenote":false, "user":"acct:miguel.ruano@hypothes.is", "displayName":null, "text":"my other text modificate", "prefix":"ed ratios of Buffer C (500 mM), ", "exact":"ethylene carbonate", "suffix":"", "start":15219, "end":15237, "tags":[ "reagent" ], "group":"__world__", "ontologies":[ "CHEBI" ], "settings":{ "bio_annotations":[ "" ] } }, { "id":"7Z1sugBbEeu9_wtvk1iAjw", "authority":"__world__", "url":"https://protocolexchange.researchsquare.com/article/pex-1069/v1", "created":"2020-09-27T00:53:59.317703+00:00", "updated":"2020-09-30T00:39:50.822216+00:00", "title":[ "Sample preparation and imaging procedures for fast and multiplexed superresolution microscopy with DNA-PAINT-ERS" ], "refs":[ ], "isReply":false, "isPagenote":false, "user":"acct:miguel.ruano@hypothes.is", "displayName":null, "text":"", "prefix":"10 minutes. Wash with PBS3. Add ", "exact":"imaging buffer", "suffix":"", "start":15162, "end":15176, "tags":[ "reagent" ], "group":"__world__", "ontologies":[ "CHEBI" ], "settings":{ "bio_annotations":[ "http://purl.obolibrary.org/obo/CHEBI_35225" ] } } ] </summary>
      nanotate hypothesis annotations biology bioinformatics
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    github.com/nanotate-tool/nanotate
  19. nanotate.bitsfetch.com nanotate.bitsfetch.com
    Nanotate
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  20. cris.maastrichtuniversity.nl cris.maastrichtuniversity.nl
    Nanotate: Semantically Annotating Experimental Protocols with Nanopublications
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    cris.maastrichtuniversity.nl/en/publications/nanotate-semantically-annotating-experimental-protocols-with-nano
  21. ceur-ws.org ceur-ws.org
    CEUR-WS.org/Vol-3127 - 13th International Conference on Semantic Web Applications and Tools for Health Care and Life Sciences 2022
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  22. www.slideshare.net www.slideshare.net
    Bioschemas: Using Schema.org for describing scientific information
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    slideshare.net/bioschemas/bioschemas-using-schemaorg-for-describing-scientific-information-80523264
  23. www.macs.hw.ac.uk www.macs.hw.ac.uk
    Bioschemas Profile Markup Generator
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    macs.hw.ac.uk/SWeL/BioschemasGenerator/
  24. www.slideshare.net www.slideshare.net
    Bioschemas overview
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    slideshare.net/bioschemas/bioschemas-overview
  25. www.slideshare.net www.slideshare.net
    Make your Web resources more discoverable with Bioschemas markup –Bio…
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    slideshare.net/bioschemas/make-your-web-resources-more-discoverable-with-bioschemas-markup-bioschemas-tutorial-june-2019
  26. bioportal.bioontology.org bioportal.bioontology.org
    NCBO BioPortal
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  27. www.biorxiv.org www.biorxiv.org
    Differential impact of TNFRSF co-stimulation on CD8+ T cell cytokine production by feedback control of surface receptor expression
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    biorxiv.org/content/10.1101/2021.07.02.450833v1
  28. www.biorxiv.org www.biorxiv.org
    Single Cell Variability of CRISPR-Cas Interference and Adaptation
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    biorxiv.org/content/10.1101/2021.07.21.453200v1
  29. www.biorxiv.org www.biorxiv.org
    CROP: A Retromer-PROPPIN complex mediating membrane fission in the endo-lysosomal system
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    biorxiv.org/content/10.1101/2021.09.06.459059v1
  30. bioschemas.org bioschemas.org
    BioSchemas
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  31. Apr 2022
  32. www.biorxiv.org www.biorxiv.org
    Tricalbin proteins regulate plasma membrane phospholipid homeostasis
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    biorxiv.org/content/10.1101/2021.06.04.447076v1
  33. www.biorxiv.org www.biorxiv.org
    A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters
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    biorxiv.org/content/10.1101/2021.09.02.458684v1
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    A genetic program boosts mitochondrial function to power macrophage tissue invasion
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    biorxiv.org/content/10.1101/2021.02.18.431643v1
  35. www.biorxiv.org www.biorxiv.org
    Polycomb Group Ring Finger Protein 6 suppresses Myc-induced lymphomagenesis
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    biorxiv.org/content/10.1101/2021.12.02.470967v1
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    Quantitative analysis of nuclear pore complex organization in Schizosaccharomyces pombe
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    biorxiv.org/content/10.1101/2021.08.11.455278v1
  37. www.biorxiv.org www.biorxiv.org
    Unique features of transcription termination and initiation at closely spaced tandem human genes
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    biorxiv.org/content/10.1101/2021.09.10.459726v1
  38. www.biorxiv.org www.biorxiv.org
    TET2-mediated epigenetic reprogramming of breast cancer cells impairs lysosome biogenesis
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    biorxiv.org/content/10.1101/2021.10.27.466063v1
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    A UPF1 variant drives conditional remodeling of nonsense-mediated mRNA decay
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    biorxiv.org/content/10.1101/2021.01.27.428318v2
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    Physical and functional interactome atlas of human receptor tyrosine kinases
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    biorxiv.org/content/10.1101/2021.09.17.460748v1
  41. www.biorxiv.org www.biorxiv.org
    Conserved exchange of paralog proteins during neuronal differentiation
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    biorxiv.org/content/10.1101/2021.07.22.453347v1
  42. Mar 2022
  43. www.biorxiv.org www.biorxiv.org
    REDUCED ER-MITOCHONDRIA CONNECTIVITY PROMOTES NEUROBLASTOMA MULTIDRUG RESISTANCE
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    biorxiv.org/content/10.1101/2021.03.01.433120v1
  44. www.biorxiv.org www.biorxiv.org
    AGO1 regulates major satellite transcripts and H3K9me3 distribution at pericentromeric regions in mESCs
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    biorxiv.org/content/10.1101/2021.07.26.453733v2
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    Autophagy suppression by TORC1 maintains epithelial plasma membrane integrity and inhibits syncytium formation
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    biorxiv.org/content/10.1101/2021.08.05.455228v1
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    GROWTH-RATE DEPENDENT AND NUTRIENT-SPECIFIC GENE EXPRESSION RESOURCE ALLOCATION IN FISSION YEAST
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    biorxiv.org/content/10.1101/2021.03.16.435638v1
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    The expression of essential selenoproteins during zebrafish development requires SECIS binding protein 2-like
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    biorxiv.org/content/10.1101/2021.11.01.466845v1
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    Specialization of actin isoforms derived from the loss of key interactions with regulatory factors
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    biorxiv.org/content/10.1101/2021.02.09.430555v1
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    Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation
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    biorxiv.org/content/10.1101/2020.12.22.423933v1
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    A human kinase yeast array for the identification of kinases modulating phosphorylation-dependent protein-protein interactions
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    biorxiv.org/content/10.1101/2021.11.18.469002v1
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    ETV2 regulates PARP-1 binding protein to induce ER stress-mediated cell death in tuberin-deficient cells
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    biorxiv.org/content/10.1101/2021.11.08.467714v1
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    Quantitative Profiling of Adaptation to Cyclin E Overproduction
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    biorxiv.org/content/10.1101/2021.07.26.453751v3
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    A Cdc42-Borg4-Septin 7 axis regulates HSCs polarity and function
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    B1-type cyclins control microtubule organization during cell division in Arabidopsis
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    biorxiv.org/content/10.1101/2021.06.29.450310v1
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    Rewiring phospholipid biosynthesis reveals robustness in membrane homeostasis and uncovers lipid regulatory players.
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    biorxiv.org/content/10.1101/2021.07.20.453065v1
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    Redundant and specific roles of EGFR ligands in the ERK activation waves during collective cell migration of MDCK cells
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    biorxiv.org/content/10.1101/2021.05.25.445569v1
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    The nucleoporin Nup50 activates the Ran guanyl-nucleotide exchange factor RCC1 to promote mitotic NPC assembly
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    biorxiv.org/content/10.1101/2021.03.31.437874v1
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    Nonsense-mediated mRNA decay utilizes complementary mechanisms to suppress mRNA and protein accumulation
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    biorxiv.org/content/10.1101/2021.05.24.445486v1
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    Balancing the length of distal tip is key for stability and signalling function of primary cilia
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    biorxiv.org/content/10.1101/2021.06.04.447095v1
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    https://biorxiv.org/cgi/content/10.1101/2021.09.01.458647
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    biorxiv.org/content/10.1101/2021.09.01.458647v1
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    Recruitment of Scc2/4 to double strand breaks depends on &#x03B3;H2A and DNA end resection
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    biorxiv.org/content/10.1101/2021.07.09.451733v1
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    https://biorxiv.org/cgi/content/10.1101/2021.09.09.459577
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  63. www.newyorker.com www.newyorker.com
    A Journey to the Center of Our Cells
    2
    2. ankostis 06 Mar 2022
      A poster hanging in many labs shows the Roche Biochemical Pathways diagram, a flowchart of cellular metabolism.

      This is the poster to look for, alike with the one with pork's meat parts.

      biology
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    newyorker.com/magazine/2022/03/07/a-journey-to-the-center-of-our-cells
  64. www.thehindu.com www.thehindu.com
    Moths are key to pollination in Himalayan ecosystem
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    thehindu.com/sci-tech/energy-and-environment/moths-are-key-to-pollination-in-himalayan-ecosystem/article25354080.ece
  65. Feb 2022
  66. www.biorxiv.org www.biorxiv.org
    A census of cell types and paracrine interactions in colorectal cancer
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    biorxiv.org/content/10.1101/2020.01.10.901579v3
  67. www.biorxiv.org www.biorxiv.org
    EMC is required for biogenesis and membrane insertion of Xport-A, an essential chaperone of rhodopsin-1 and the TRP channel
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    biorxiv.org/content/10.1101/2021.02.01.429115v1
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    Structured decomposition improves systems serology prediction and interpretation
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    biorxiv.org/content/10.1101/2021.01.03.425138v2
  69. www.biorxiv.org www.biorxiv.org
    Major functional bias for mitochondrial complexes in genome-wide CRISPR screens
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    biorxiv.org/content/10.1101/2020.08.31.273730v1
  70. www.biorxiv.org www.biorxiv.org
    CDK4/6 inhibitors induce replication stress to cause long-term cell cycle withdrawal
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    1. lucyparfitt16 21 Jan 2022

      Frere, J. J., Serafini, R. A., Pryce, K. D., Zazhytska, M., Oishi, K., Golynker, I., Panis, M., Zimering, J., Horiuchi, S., Hoagland, D. A., Moller, R., Ruiz, A., Overdevest, J. B., Kodra, A., Canoll, P. D., Goldman, J. E., Borczuk, A. C., Chandar, V., Bram, Y., … tenOever, B. (2022). SARS-CoV-2 infection results in lasting and systemic perturbations post recovery (p. 2022.01.18.476786). https://doi.org/10.1101/2022.01.18.476786

      is:preprint lang:en COVID-19 recovery long covid research persistent symptom animal study biology
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    The Other Invisible Hand | NOEMA
    4
    1. chrisaldrich 05 Jan 2022

      https://www.noemamag.com/the-other-invisible-hand/?utm_source=indieweb&utm_medium=social&utm_campaign=indieweb

      Raw capitalism mimics the logic of cancer within our body politic.

      Folks who have been reading David Wengrow and David Graeber's The Dawn of Everything are sure to appreciate the sentiment here which pulls in the ideas of biology and evolution to expand on their account and makes it a much more big history sort of thesis.

      capitalism read big history cooperation the commons economics biology GWBC
    3. chrisaldrich 05 Jan 2022
      Unfortunately, the ideas most economists use have been too influenced by “methodological individualism,” rather than the more scientifically supported view of us as a super-social, super-cooperative, intensely interdependent species. Often, this economics-style individualism is of the Thomas Hobbes variety, which paints humans in “a state of nature,” waging a “war of all against all.”

      This statement in the framing of biology is quite similar to the framing in anthropology and archaeology that David Graeber and David Wengrow provide in The Dawn of Everything.

      Perhaps we should be saying (especially from a political perspective): Cooperation is King!

      cooperation cooperation is king GWBC The Dawn of Everything biology anthropology economics
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    (13) (PDF) Human ultrasociality and the invisible hand: foundational developments in evolutionary science alter a foundational concept in economics
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    1. chrisaldrich 05 Jan 2022

      Human ultrasociality and the invisible hand: foundational developments in evolutionary science alter a foundational concept in economics

      December 2014

      Journal of Bioeconomics 17(1)

      DOI: 10.1007/s10818-014-9192-x

      by David Sloan Wilson and John Malcolm Gowdy

      https://www.researchgate.net/publication/269637211_Human_ultrasociality_and_the_invisible_hand_foundational_developments_in_evolutionary_science_alter_a_foundational_concept_in_economics

      <small><cite class='h-cite via'>ᔥ <span class='p-author h-card'>Jag Bhalla</span> in The Other Invisible Hand - NOEMA (<time class='dt-published'>01/05/2022 12:12:29</time>)</cite></small>

      Cross reference: https://hyp.is/g3DHAm5jEey8o3NhnLbsew/www.noemamag.com/the-other-invisible-hand

      want to read cooperation invisible hand economics biology
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      Translational kinetics of mRNA-LNP delivered by different routes in vivo. Quantification of the bioluminescent signal measured in BALB/c mice injected with (A) 0.1 μg, (B) 1.0 μg or (C) 5.0 μg mRNA-LNPs by intradermal (i.d.), intramuscu

      Diagrams of the presence of proteins versus time in various administration methods in mouse

      covid19-vaccine mRNA biology
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    Column: You go, Joe! Thank heavens the president is standing up for science, public health and vaccines
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    1. adam5 11 Sep 2021
      Thursday, he announced that private-sector businesses with more than 100 employees must make sure their workers are fully vaccinated or be tested each week before coming to work.The

      surveillance state: meet the first candidate for a govnerment created retroviral biotracker:

      COVID-19 and it's quanta of "so long, freedom"

      #bnio bio biology 1994 1984
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    1. lucyparfitt16 07 Sep 2021

      Michael Mina on Twitter: “With all the news of vaccines & immunity, did you know measles infections destroy immunity and cause ‘Immune Amnesia’, increasing risk of all other infections Our research in ‘15 & ‘19 discovered this & the abbreviated story is written up nicely here: 1/ https://t.co/t5DKoQljxM” / Twitter. (n.d.). Retrieved September 7, 2021, from https://twitter.com/michaelmina_lab/status/1435037668027641861

      is:tweet lang:en vaccine immunity research measles mortality childhood mortality children immune memory immune amnesia modeling biology
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  146. Jul 2021
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    A polycomb-independent role of EZH2 in TGFβ1-damaged epithelium triggers a fibrotic cascade with mesenchymal cells
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    thermofisher.cn/cn/zh/home/life-science/protein-biology/protein-biology-learning-center/protein-biology-resource-library/pierce-protein-methods/immunoprecipitation-ip.html
  154. www.biorxiv.org www.biorxiv.org
    A genome-scale yeast library with inducible expression of individual genes
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    biorxiv.org/content/10.1101/2020.12.30.424776v2
  155. www.biorxiv.org www.biorxiv.org
    Diverse natural variants suppress mutations in hundreds of essential genes
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    biorxiv.org/content/10.1101/2020.11.24.395855v2
  156. www.biorxiv.org www.biorxiv.org
    Behavioral fingerprints predict insecticide and anthelmintic mode of action
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    biorxiv.org/content/10.1101/2021.01.27.428391v1
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    JSTA: joint cell segmentation and cell type annotation for spatial transcriptomics
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    biorxiv.org/content/10.1101/2020.09.18.304147v1
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    Characterization of histone inheritance patterns in the Drosophila female germline
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    biorxiv.org/content/10.1101/2020.08.18.255455v1
  159. www.biorxiv.org www.biorxiv.org
    Primary platinum resistance and immune exclusion in ovarian carcinomas with high expression of the homologous recombination mediator RAD51
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    Dynamic association of IκBα to chromatin is regulated by acetylation and cleavage of histone H4
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    Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth
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  162. www.biorxiv.org www.biorxiv.org
    A highly conserved binding pocket on PP2A-B56 is required for shugoshin binding and cohesion protection
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  163. www.biorxiv.org www.biorxiv.org
    Quantifying signal persistence in the T cell signaling network using an optically controllable antigen receptor
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    biorxiv.org/content/10.1101/2020.10.30.362194v1
  164. www.biorxiv.org www.biorxiv.org
    Aurora Kinase A proximity interactome reveals centriolar satellites as regulators of its function during primary cilium biogenesis
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  165. www.biorxiv.org www.biorxiv.org
    A cryo-EM structure of metazoan TRAPPIII, the multisubunit complex that activates the GTPase Rab1
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    biorxiv.org/content/10.1101/2020.12.17.423307v1
  166. www.efsyn.gr www.efsyn.gr
    Δηλητηριασμένη «επιστήμη»
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    1. ankostis 07 Jul 2021
      από τις 53 μελέτες που είχαν υποβληθεί από παραγωγούς της γλυφοσάτης στην EFSA μόλις δύο ήταν επιστημονικά αξιόπιστες με βάση τα διεθνή πρότυπα του ΟΟΣΑ. Οι 34 ήταν μη αξιόπιστες ενώ οι υπόλοιπες 17 μερικά αξιόπιστες.

      Πάμε πάλι: η Επιστήμη δεν αποφαίνεται για θετικά συμπεράσματα, αλλα μονο διαψεύδει.

      epistemology biology corporatocracy Monsanto-Roundup
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    efsyn.gr/stiles/ano-kato/301350_dilitiriasmeni-epistimi
  167. mlech26l.github.io mlech26l.github.io
    The wormnet project - Part 1
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    1. mshook 05 Jul 2021
      In our research, i.e., the wormnet project, we try to build machine learning models motivated by the C. elegans nervous system. By doing so, we have to pay a cost, as we constrain ourselves to such models in contrast to standard artificial neural networks, whose modeling space is purely constraint by memory and compute limitations. However, there are potentially some advantages and benefits we gain. Our objective is to better understand what’s necessary for effective neural information processing to emerge.
      celegans nn neuron ml biology
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  168. www.sciencedaily.com www.sciencedaily.com
    Carl Linnaeus Invented The Index Card
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    1. chrisaldrich 04 Jul 2021
      “Although a seemingly mundane and simple innovation, Linnaeus' use of index cards marks a major shift in how eighteenth-century naturalists thought about the order of nature,” says Mueller-Wille. The natural world was no longer ordered on a fixed, linear scale, but came to be seen as a map-like natural system of multiple affinities.

      Ha!

      Roughly the idea I'd just written!

      The idea of reordering nature this way would have been fantastic, particularly in light of the general prior order of the cosmos based on the scala naturae or Great Chain of Being.

      Compare this with Ernst Haeckel's Tree of Man. What year was this in relation? Was the idea of broader biological networks and network-like structure thought of prior to this?

      scala naturae order complexity biology
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    sciencedaily.com/releases/2009/06/090616080137.htm
  169. www.biorxiv.org www.biorxiv.org
    Vaccinia virus hijacks ESCRT-mediated multivesicular body formation for virus egress
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    biorxiv.org/content/10.1101/2020.07.15.203935v1
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    A dynamic and spatially periodic micro-pattern of HES5 expression underlies the probability of neuronal differentiation in the mouse spinal cord
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    biorxiv.org/content/10.1101/2020.08.03.234369v2
  171. Jun 2021
  172. www.biorxiv.org www.biorxiv.org
    Aneuploid cells activate NF-κB to promote their immune clearance by NK cells
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    biorxiv.org/content/10.1101/2020.06.25.172239v1
  173. www.cell.com www.cell.com
    Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids
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  174. phys.org phys.org
    Study finds potentially druggable process of SARS-CoV-2 replication
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    phys.org/news/2021-06-potentially-druggable-sars-cov-replication.html
  175. osf.io osf.io
    Variants of Concern responsible for SARS-CoV-2 vaccine breakthrough infections from India
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    osf.io/fgd4x/
  176. www.biorxiv.org www.biorxiv.org
    CyclinD1 controls development of cerebellar granule cell progenitors through phosphorylation and stabilization of ATOH1
    1
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    biorxiv.org/content/10.1101/2020.03.27.010926v1
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    Integrated requirement of non-specific and sequence-specific DNA binding in MYC-driven transcription
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    biorxiv.org/content/10.1101/2020.05.04.076190v2
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    Sequence analysis allows functional annotation of tyrosine recombinases in prokaryotic genomes
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    biorxiv.org/content/10.1101/542381v1
  179. www.biorxiv.org www.biorxiv.org
    Subepidermal blisters are healed by wedge-shaped keratinocytes of hair follicle origin
    1
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    biorxiv.org/content/10.1101/2020.04.08.032326v2
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    Pancreatic Cancer Intrinsic PI3Kα Activity accelerates Metastasis and rewires Macrophage Component
    1
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    biorxiv.org/content/10.1101/2020.09.23.307884v1
  181. May 2021
  182. biorxiv.org biorxiv.org
    Advancing the sharing of research results for the life sciences
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    Somatic transposition in the Drosophila intestine occurs in active chromatin and is associated with tumor suppressor gene inactivation
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    biorxiv.org/content/10.1101/2020.07.10.166629v1
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    REPRESSION BY HDAC3 AND DAX1 MEDIATES LINEAGE RESTRICTION OF EMBRYONIC STEM CELLS
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    biorxiv.org/content/10.1101/2020.09.10.291013v1
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    Gametic specialization of centromeric histone paralogs in Drosophila virilis
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    biorxiv.org/content/10.1101/530295v1
  186. www.biorxiv.org www.biorxiv.org
    Spurious regulatory connections dictate the expression-fitness landscape of translation factors
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  187. www.biorxiv.org www.biorxiv.org
    hu.MAP 2.0: Integration of over 15,000 proteomic experiments builds a global compendium of human multiprotein assemblies
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    biorxiv.org/content/10.1101/2020.09.15.298216v1
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    http://biorxiv.org/cgi/content/short/2020.10.21.348854
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  189. blogs.sciencemag.org blogs.sciencemag.org
    Spike Protein Behavior
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    1. ankostis 13 May 2021
      This might explain the seemingly higher frequence of this serious complication compared to the mRNA delivery methods which have other problems, in particular related to the ionizable cationic lipid packaging which have strong toxic effects.

      On brain tissue damages due to AstraZeneca.

      covid19 biology
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  190. localhost:8080 localhost:8080
    Research on Demand | DeepDyve
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    1. chrisaldrich 13 May 2021

      <small><cite class='h-cite via'>ᔥ <span class='p-author h-card'>Maël Montévil</span> in "I've redone my #academic website using @eleven_ty It is fun to play with various data sources like @CrossrefOrg api as a complement to #webmention. I also took some inspiration and code from @nhoizey https://t.co/ULaTAMDYZC" / Twitter (<time class='dt-published'>05/12/2021 17:52:48</time>)</cite></small>

      Theoretical biology AND webmentions? I'm in.

      following theoretical biology ITBio mathematics
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  191. www.biorxiv.org www.biorxiv.org
    Multidimensional Chromatin Regulation of Cell Lineage Differentiation in a Metazoan Embryo
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    biorxiv.org/content/10.1101/2020.05.18.101584v1
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    CODEX, a neural network approach to explore signaling dynamics landscapes
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    biorxiv.org/lookup/doi/10.1101/2020.08.05.237842
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    Proteome constraints reveal targets for improving microbial fitness in nutrient-rich environments
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    biorxiv.org/content/10.1101/2020.10.15.340554v1
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    Combinatorial action of transcription factors in open chromatin contributes to early cellular heterogeneity and organizer mesendoderm specification.
    1
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    biorxiv.org/content/10.1101/2020.02.26.966168v1
  195. www.quantamagazine.org www.quantamagazine.org
    The Hard Lessons of Modeling the Coronavirus Pandemic
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  196. www.biorxiv.org www.biorxiv.org
    Carbonic anhydrase VII regulates dendritic spine morphology and density via actin filament bundling
    1
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    biorxiv.org/content/10.1101/736868v1
  197. Apr 2021
  198. www.biorxiv.org www.biorxiv.org
    CDCP1 controls compensatory renal growth by integrating Src and Met signaling
    1
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    biorxiv.org/content/10.1101/789339v1
  199. www.biorxiv.org www.biorxiv.org
    Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2
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    biorxiv.org/content/10.1101/2020.04.06.027896v2
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    Replicated chromatin curtails 53BP1 recruitment in BRCA1-proficient and -deficient cells
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    biorxiv.org/content/10.1101/2020.02.24.947168v1
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    CASB: A concanavalin A-based sample barcoding strategy for single-cell sequencing
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    biorxiv.org/content/10.1101/2020.10.15.340844v1
  202. localhost:8080 localhost:8080
    Research on Demand | DeepDyve
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  203. www.biorxiv.org www.biorxiv.org
    An ATM-MYBL2-CDC7 axis regulates replication initiation and prevents replication stress in pluripotent stem cells
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  204. www.pennington.com www.pennington.com
    All You Need to Know About Perennial Ryegrass
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  205. www.biorxiv.org www.biorxiv.org
    Urinary proteome profiling for stratifying patients with familial Parkinsons disease
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    Reflux of Endoplasmic Reticulum proteins to the cytosol yields inactivation of tumor suppressors
    1
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    biorxiv.org/content/10.1101/2020.04.13.038935v1
  207. www.biorxiv.org www.biorxiv.org
    Cryo-EM reveals the complex architecture of dynactin's shoulder and pointed end
    1
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    biorxiv.org/content/10.1101/2020.07.16.206359v1