another patient with the 541 variant potentially not in cis with ala1038val. G1961E has been classified as pathogenic by the ABCA4 VCEP

another patient with the 541 variant potentially not in cis with ala1038val. F655C is path/LP in clinvar

Case#: Patient 13, 35yo

DiseaseAssertion: STGD

FamilyInfo: Family 8

CasePresentingHPOs:

CaseHPOFreeText: Visual acuity=0.017. OCT ft (μm)=163. MP (dB)=0. Fundus=3(extensive atrophic-appearing RPE changes). ERG=3(abnormal responses involving both rods and cones). mfERG=4(subnormal mfERG in the entire test field (0°–30°) plus pathologic Ganzfeld ERG).

CaseNotHPOs:

CaseNotHPOFreeText:

GenotypingMethod: PCR of coding regions, intron/exon boundaries, and 5′ and 3′ regions of ABCA4; Standard cycle-sequencing reactions with BigDye Terminator

PreviouslyPublished:

Variant: L541P; R1098C

CAID: CA226911;

SupplementalData: n/a

Case#: 4, 34 year old male

DiseaseAssertion: Stargardt Disease

FamilyInfo: NR

CasePresentingHPOs: NR

CaseHPOFreeText: NR

CaseNotHPOs:

CaseNotHPOFreeText: NR

Genotyping Method: Analyzing the ABCA4 gene

PreviouslyPublished: NR

Variant: 4469G>A

ClinVar: NR

CAID: NR

SupplementalData: NR

PMID: 23949494 HGNC: 34 Gene: ABCA4 DiseaseAssertion: Stargardt Disease

gnomad 0.0001 frequency

I don't understand what this means, but how I interepret it is if an homozygous STGD1 variant appears at a lower frequency that it is less severe.

I don't understand what this means, but how I interepret it is if an homozygous STGD1 variant appears at a lower frequency that it is less severe.

SupplementalData:

SupplementalData:

This variant was found in Patient 074752 in cis with a nonsense (c.6088C>T) and in trans with an intronic variant (c.4253+43G>A); neither of which has been curated yet by the ABCA4 VCEP

Not sure if this variant is c.1988G>A or c.1989G>A.

This variant is listed for Stargardt DNAID#067322 in trans with c.5603A>T p.(Asn1868Ile). No phenotype information provided.

Case#: Female, family #5, Patient #20

DiseaseAssertion: STGD

FamilyInfo: Proband's sister presented with same clinical prognosis. Sister diagnosed with pattern dystrophy and photoaversion at age 57, with difficulty seeing at night. Sister has nuclear sclerotic and cortical cataracts in both eyes.

CasePresentingHPOs: HP:0000662, HP:0000603, HP:0000603, HP:0000493

CaseHPOFreeText: Proband presented with localized blur at age 62, (late onset) in her left eye. BVCA 20/20-3 and 20/20-2 at age 70. Also has macular lesions with stage 2 fundus flecks.

CaseNotHPOs: n/a

CaseNotHPOFreeText: n/a

Genotyping Method: Genotyping performed at Columbia University, sequencing technology used is not disclosed.

PreviouslyPublished: n/a

Variant: p.N18681, IVS36:c.5196+1G>A

ClinVar: M2) 99067, M6) 99351

CAID: N/A

SupplementalData: Fig 1: Pedigree illustrating ABCA4 variants and the associated Stargardt phenotype for 5 families. Proband Labeled w/ white arrow for each family. Fig 2: retinal scan measuring melanin in 4 patients of family 2. Panel shows bull's-eye ring of RPE atropy. Fig 3: Macular SD-OCT line profile from b-scans. Reflectivity plotted against function of retinal depth. Table 1: table shows patients with p.N18681 variant, type of mutation, and pathogenicity class. Table 2: Patients, age on-set and first symptom

Case#: Patient 225, Female, age of onset 7 y.o, Poland

DiseaseAssertion: STGD-1

FamilyInfo: no given family information.

CasePresentingHPOs: HP:0007722, HP:0000608, HP:0025158

CaseHPOFreeText: RPE atrophy, macular degeneration, central hyper-autofluorescence in fundus autofluorescence

CaseNotHPOs: n/a

CaseNotHPOFreeText: n/a, non-proband identified HPO's mentioned, but not assignable to individual proband.

Genotyping Method: DNA isolated from peripheral blood from patients and relatives via MagNA Pure 24, samples screened with MIPs targeting 108 genes involved in pathogensis of IRD's. PCR completed on library, analysed with NGS fragment analysis kit.

PreviouslyPublished: yes

Variant: c.[1622T>C;3113C>T]

ClinVar: 99067, 7894

CAID: n/a

gnomeAD 0.0001266 allele frequency

SupplementalData: Fig1: List of families displaying pseudo-dominant inheritance. Fig2: Number of alleles for most common variants.

It is known that patients harbouring p.(Gly1961Glu) or p.(Asn1868Ile) allele share some common clinical characteristics and present with a milder disease phenotype than patients carrying other alleles. A typical feature of patients with p.(Gly1961Glu) is BEM, which is otherwise present in around 20% of all STGD1 patients.

It is known that patients harbouring p.(Gly1961Glu) or p.(Asn1868Ile) allele share some common clinical characteristics and present with a milder disease phenotype than patients carrying other alleles. A typical feature of patients with p.(Gly1961Glu) is BEM, which is otherwise present in around 20% of all STGD1 patients.

ABCA4 variant revealed but not target of research and doesn't seem to amount to anything Variantc.3113C>T p.(Ala1038Val)

ABCA4 variant revealed but not target of research and doesn't seem to amount to anything Variantc.3113C>T p.(Ala1038Val)

Case#: Patient #35, male, 35yo at report, 14yo at onset,

DiseaseAssertion: STGD

FamilyInfo: family 30, segregation was noted as "yes" but no other details provided

CasePresentingHPOs:

CaseHPOFreeText:

CaseNotHPOs:

CaseNotHPOFreeText:

GenotypingMethod:

PreviouslyPublished: n/a

Variant: allele 1: A1038V;L541P allele 2: G818E

ClinVar: 99135

CAID: CA227000

SupplementalData: supplemental table 1

Case#: STGD87, 10-14yo at onset, German

DiseaseAssertion: STGD

FamilyInfo: segregation in family

CasePresentingHPOs:

CaseHPOFreeText: "The diagnosis of STGD was based on the demonstration of bilateral impairment of central vision and the appearance of perimacular and/or peripheral yellow-white flecks, with or without atrophy of the central retinal-pigment epithelium and a normal or only mildly abnormal flash electroretinogram when recorded in early stages of the disease."

CaseNotHPOs:

CaseNotHPOFreeText:

GenotypingMethod: denaturing gradient gel electrophoresis, dHPLC, and SSCP analysis, PCR amplification of individual coding exons and flanking intron sequences, direct DNA sequencing

PreviouslyPublished: n/a

Variant: Q1750X; 2588G→C in trans "Correct segregation of disease alleles was demonstrated in all 39 cases in which family samples were available for study"

ClinVar: 7879

CAID: CA119128

SupplementalData: n/a

Case#: STGD47/164, 10-14yo at onset, German

DiseaseAssertion: STGD

FamilyInfo: segregation in family

CasePresentingHPOs:

CaseHPOFreeText: "The diagnosis of STGD was based on the demonstration of bilateral impairment of central vision and the appearance of perimacular and/or peripheral yellow-white flecks, with or without atrophy of the central retinal-pigment epithelium and a normal or only mildly abnormal flash electroretinogram when recorded in early stages of the disease."

CaseNotHPOs:

CaseNotHPOFreeText:

GenotypingMethod: denaturing gradient gel electrophoresis, dHPLC, and SSCP analysis, PCR amplification of individual coding exons and flanking intron sequences, direct DNA sequencing

PreviouslyPublished: n/a

Variant: IVS13+1G→A; 2588G→C in trans "Correct segregation of disease alleles was demonstrated in all 39 cases in which family samples were available for study"

ClinVar: 7879

CAID: CA119128

SupplementalData: n/a

Case#: Hwang Case 4, male, 52yo at report, 45yo at onset

DiseaseAssertion: Stargardt

FamilyInfo: Family history was not significant for ocular disease.

CasePresentingHPOs: HP:0000545

CaseHPOFreeText: declining vision OS, BCVA was 20/100 OD and 20/70 OS. Spherical refractive error measured −3.00 OD and −3.25 OS. Posterior segment examination was significant for central atrophy and classic peripheral pisciform flecks sparing the peripapillary regions OU (Figure 4, A and B). Autofluorescence imaging demonstrated inner atrophic flecks and outer hyperautofluorescent flecks. Moderate peripapillary hypoautofluorescence, but not atrophy, was present (Figure 4, C and D).

CaseNotHPOs: HP:0500087

CaseNotHPOFreeText:

GenotypingMethod: Genotyping was performed by the ABCR400 microarray followed by direct sequencing to confirm identified variants.

PreviouslyPublished: n/a

Variant: P1380L and S1696N

ClinVar: 7904

CAID: CA129033

SupplementalData: n/a

Case#: Hwang Case 1, US, male, 55yo at report, 18yo at onset

DiseaseAssertion: Stargardt disease

FamilyInfo: Family history was not significant for ocular disease

CasePresentingHPOs: HP:0007663, HP:0500087, HP:0000603, HP:0000512

CaseHPOFreeText: BCVA of 20/350 OD and 20/200 OS. Spherical refractive error measured −3.5 OD and −2.0 OS. Posterior segment examination and autofluorescence imaging were significant for sharply demarcated central and peripapillary zones of atrophy and the absence of fleck lesions (Figure 1, A–D). Humphrey visual fields demonstrated bilateral central scotomas with eccentric fixation at the inferior border.

CaseNotHPOs:

CaseNotHPOFreeText:

GenotypingMethod: Genotyping was performed by the ABCR400 microarray followed by direct sequencing to confirm identified variants.

PreviouslyPublished: n/a

Variant: P1380L and IVS40 + 5G>A

ClinVar: 7904

CAID: CA129033

SupplementalData: n/a

Case#: Case 3, 39yo

DiseaseAssertion: BEM, RCD

FamilyInfo: n/a

CasePresentingHPOs:

CaseHPOFreeText: a ring of increased AF surrounding decreased foveal AF, visual acuity= 6/6, 6/6

CaseNotHPOs:

CaseNotHPOFreeText: acquired toxic aetiology

GenotypingMethod: The entire coding sequence (50 exons), including exon–intron boundaries, of the ABCA4 gene of each patient was screened using single‐stranded conformational polymorphism (SSCP) analysis and direct sequencing.

PreviouslyPublished: n/a

Variant: Val552Ile heterozygous

CAID: CA239745

SupplementalData: n/a

PMID: 32843395

Gene: ABCA4

Disease: Stargardt

PMID: 35120629

Gene: ABCA4

Disease: Stargardt disease

PAPER USED TO SCORE PS4

PMID: 12796258

Gene: ABCA4

Disease: autosomal recessive cone-rod dystrophy

PMID: 32845050

Gene: ABCA4

Disease: Stargardt Macular Degeneration

PMID: 17296903

Gene: ABCA4

Disease: hereditary retinal disease

PMID:39215425

Gene: ABCA4

HGNC ID: 34

case27-year-old male, the brother of case 1

DiseaseAssertion: Table 1 The summary of the clinical assessment of IRD patients’ family in this research fro there down they did a whole pannel on the family

Pedigree one can be fore form the beggginnings of case presention section?

CasePresentingHPOs: Case 2, a 27-year-old male, the brother of case 1 had blurry vision which was not corrected with an eyeglass and inconveniences under bright light starting from 14 years ago. Case 2 also underwent a fundus examination after finding that case 1 was RP. In further examination of those patients and their family members found that case 1 was confirmed as RP and case 2

CaseHPOFreeText:NA

CaseNotHPOs:NA

CaseNotHPOFreeText:NA

Genotyping Method:NA

PreviouslyPublished:NA

Variant:NA

ClinVar:

CAID:NA

SupplementalData:NA

Inheritance pattern Autosomal Recessive

PMID:39967245

Gene: ABCA4

HGNC ID: 34

Case#:39 man

DiseaseAssertion:NA

FamilyInfo:NA

CasePresentingHPOs:Snellen in both eye, visual impairment with night blindnessisual acuity was 20/20Snellen in both eyes, with a minor correction for astig-matism. The anterior segment and intraocular pressurewere within normal limits. On fundus examination, dif-fuse fleck-like lesions were scattered both inside and out-side the arcades, while sharply demarcated areas ofmacular atrophy with foveal sparing, more pronouncedin the left eye, were visible.

CaseHPOFreeText:NA

CaseNotHPOs:NA

CaseNotHPOFreeText:

Genotyping Method:Next-Generation Sequencing (NGS), using theTruSight One Clinical Exome sequencing panel on anIllumina NexSeq500 platform, enriching for 4800 genesincluding ABCA4, CNGB3, ELOVL4, PROM1, and PRPH2

PreviouslyPublished:Under refernces?

Variant:WDR19 variants:the novel deletion at c.1777 + 1 within the donor splicingsite (class 4) and the rare c.1430 G>T variant causing theamino-acid substitution p.(Arg477Leu) (class 3) in the putative protein. Additionally, a heterozygous c.1793A>G(class 3) variant in the CDH23 gene was found, though it was deemed as not contributive to the patient’s clinical phenotype. All reported variants were confirmed throughSanger sequencing

ClinVar:NA

CAID:NA

SupplementalData:NA

Case#: Family 12 Proband, male, 43yo at onset, Portuguese

DiseaseAssertion: Stargardt

FamilyInfo: no affected family members in pedigree (Fig. 1)

CasePresentingHPOs: HP:0007663

CaseHPOFreeText: "The criteria for STGD phenotype included bilateral central vision loss and pigmentary macular lesions, normal caliber of retinal vessels, absence of pigmented bone spicules, and compatibility with recessive mode of inheritance." Moderate central retinal changes, decreased mfERG responses exclusively in the central 15 degrees

CaseNotHPOs:

CaseNotHPOFreeText:

PreviouslyPublished: n/a

Variant: p.Glu1574X; p.Val931Met. Several other polymorphisms also reported. ABCR400 gene chip microarray, DHPLC

ClinVar: 1460063

CAID: CA341283936

SupplementalData: n/a

Annotating here since the full text is a PDF.

Case#: Family AR321 proband, US, 6yo at onset

DiseaseAssertion: Stargardt

FamilyInfo: proband and two other siblings are affected

CasePresentingHPOs: The essential and defining features of STGD were (1) pedigrees with at least one living affected individual compatible with autosomal recessive inheritance; (2) an ophthalmoscopically characteristic retinal disorder in families with both parents living; (3) bilateral central visual loss with both “beaten metal” elliptical foveal dystrophy and temporal pallor of the optic discs, documented by retinal color photography, with or without yellow-pigment epithelial flecks in the macular and/or retinal “near periphery”; and (4) the characteristic fluorescein angiographic feature of a dark choroid (Blacharski 1988).

CaseHPOFreeText:

CaseNotHPOs:

CaseNotHPOFreeText: (1) evidence of autosomal dominant inheritance; (2) any history of night blindness, loss of peripheral vision, or "retinitis pigmentosa"; (3) cataracta complicata or cells in the vitreous; (4) substantially abnormal electroretinographic or electrooculographic responses; (5) no fluorescein angiography performed or no dark choroid documented; (6) neurological disease (including loss of cognition or seizures); 7) drug exposures (especially to antimalarial and agents known to cause crystalline retinopathies); or (8) any "atypical" maculopathies in which a unique diagnosis of STGD could not be established.

PreviouslyPublished: PMID: 8533764

Variant: c.3113C>T p.A1038V; c.1715G>C p.R572P . Heteroduplex and SSCP analyses were used to screen the 50 exons of ABCA4. Linkage analysis and haplotype analysis were previously performed

ClinVar: 99073

CAID: CA226919

SupplementalData: n/a

Case#: Bryant Subject JB260, US

DiseaseAssertion: Stargardt

FamilyInfo:

CasePresentingHPOs: "Stargardt disease is a childhood-onset macular degeneration and is most commonly caused by mutations in ABCA4. Characteristic yellow flecks are typically seen under the macula during a fundus exam."

CaseHPOFreeText:

CaseNotHPOs:

CaseNotHPOFreeText:

GenotypingMethod: WES; previously screened using arrayed primer extension (APEX) multigene panels for the relevant disease and no disease-causing variants had been identified; PCR and Sanger for verification

PreviouslyPublished: n/a

Variant: c.6119G>A p.Arg2040Gln; c.2879del p.Ala960Aspfs*17

CAID: CA232815

SupplementalData:

Case#: Patients were identified from the inherited retinal disease (IRD) database at UC San Diego (UCSD).

DiseaseAssertion: RP with macular edema

FamilyInfo:

CasePresentingHPOs:

CaseHPOFreeText: Dx of RP based on "a history of progressive peripheral vision loss or nyctalopia, and ocular examination findings of RP including bone spicule pigmentation, disc pallor and attenuated vessels and genetic confirmation."

CaseNotHPOs:

CaseNotHPOFreeText:

GenotypingMethod: Next-generation sequencing (NGS), exome sequencing, and/or targeted Sanger sequencing were the primary genetic testing approaches.

PreviouslyPublished: PMID:10206579 is referenced but it seems a reference to the variant and not the proband

Variant: c.6383A>G (p.His2128Arg); c.3G>T (p.Met1?). phase unknown

ClinVar: 99455

CAID: CA227399

SupplementalData: Variant is found in table S2

something I would like to learn more about is the effectiveness on individuals who are not biological women, for example trans women or biological men. Both of these demographics can absolutely experience some form of IPV. I believe these 2 groups can have very different experiences in how they try to cope with abuse and also how they are expected to cope with abuse. (e.g., men expected to not take abuse seriouslty due to the sole fact that they are men). I would love to learn more if art therapy can still aid in healing for these groups.

after the study, it was reported that women not only improved cognitively but also improved in the way they see themselves physically, and taking back ownership of their own bodies and feeling more confident overall. This is important to me because it just emphasizes the fact that everything is interconnected and that one aspect of mental health always affects the others.

group therapy is helpful in having other women go through similar experiences promotes a healthy atmosphere and allows connection between eachother in a safe environment.

art therapy aims to "diminish impulsive responses", which I think is very important because therapy in itself will not be helpful if you can't find the root of the problem. Most traumas feed on impulsivity, and how the brain responds to an individual's first thought, which can usually be negative.

note on how any art form can reveal meaning

art therapy can access different parts of the brain that talk-based therapy cannot. sensorymotor skills are activated through artmaking and aids understanding in one's emotions and how it manifests physically.

this is notable to me because i think remembering these 5 themes can help me aid my future patients when i'm in the art therapy field. a. rebuilding myself b. art symbolically telling my story c. reconnecting d. promoting a healing space e. hoping for a better future

because victims have a skewed sense of reality, they often find themselves in a place where they believe that the abuse is actually their fault, making them hesitant to speak out about said abuse. because art therapy isa nonverbal expression of therapy, these barriers can be torn down and provide a safe space for the victim in telling their story.

art therapy can be used in many ways, such as using it as a replacement for verbal expression, or a stepping stone to eventually having the ability to put their trauma into words, or a hybrid of both. this interests me because I myself, plan to become an art therapist and want to know of the many ways art therapy can be used to patients. and it's important for em to note that this method of therapy can't be utilized in the same way for everyone, and there are adjustments that need to be made to make sure every therapy session is tailored to each individual's own needs.

understanding why and how vicitms were abused and reanalyzing that trauma can be the first step into a positive direction. I think this is very interesting because sometimes I don't think of looking at trauma in the way of looking at it from a different perspective, and it's easy to drown in your own suffering and getting into your head of "why is this happening to me?", "reinterpreting their trauma", as the articles calls it, allows the victims to take control of their own life again.

it's important to study the aftermath effects of therapy as well, such as PTG, which is posttramatic growth, where victims find a "deeper appreciation of life, increased personal strength, enchanced relationships..." (page 2).

and this can lead to the importance of art therapy as it is a type of therapy where words do not need to be expressed. having the body go through motions and putting their thoughts into something they create with their hands can aid in the healing process.

3 types of trauma have arised from IPV, those being personal, relational and betrayal trauma (trust and security in relationship being violated), which in turn caused many mental, sexual and physical health problems that affect the victim's ability to function in their life.

More often than not I just go simple pencil all the way through.

Sometimes I use a Pilot Coleto Hi-tec C multipen with four different colors to make things more interesting and differentiate between types of data, particularly within the boxes so I know what happens from one box to the next, particularly when going back to prior boxes to add in historical information. (I also tend to go with their 0.3mm fine tip ink refills for being able to pack more writing into small boxes!) Sometimes I'll do the starting pitcher and their work in black, and relievers in blue, purple, and orange rotating through to differentiate each pitcher's work to make it easier to keep up with their individual data, especially when I do full pitch counts.

Sometimes I'll take along a Mitsubishi 772 "editor's pencil" that has both red and blue lead to add in some color. Often it's a simple line for pitcher changes or for substitutions across an individual line to distinguish when a sub came into the game.

Sometimes I'll use a typewriter with a bichrome ribbon and switch between black and red ink to help break up some data, or to highlight things like RBIs to make summing things easier in the end. Example: https://www.reddit.com/r/BaseballScorecards/comments/1s33f1d/20260324_tampa_bay_rays_vs_atlanta_braves_spring/ which has red lines between pitchers and red "I"s to break up substitutions.

Looking at example cards that get posted here will give you some ideas and pointers. Usually one can puzzle out what the scorer was doing using different colors or highlighters.

A lot of how I score depends on my mood, where I'm watching a game, how much time I want to put into it all, and which tools I have at hand. Experiment. Have fun. Do what works best for you. There's no single "right" way, just the same way there are thousands of different formats in scorecard formats.

reply to u/Alej_Betancourt at https://reddit.com/r/BaseballScorecards/comments/1s3mbzt/your_advice_for_a_rookie_highlighters_and/

Pathos appeals to emotions such as sadness, fear, or happiness. Writers use pathos to help the audience emotionally connect to the message and feel motivated to respond.

Logos focuses on logic, facts, and reasoning. Using evidence and clear explanations helps make an argument more convincing and reasonable to the audience.

Ethos is about credibility and trust. If the audience believes the writer is knowledgeable and trustworthy, they are more likely to accept the argument being made.

A rhetorical situation includes the writer, the audience, and the purpose. All three must work together for communication to be effective, and changing one affects how the message is understood.

Rhetoric is about persuading an audience through writing or speaking. This shows that communication is not just about sharing information, but about influencing how people think or act.

for - Medium article - cogress - Part 1 - progress trap - James Gien Wong - definition - cogress - to - Medium article cogress - Part 2 - progress trap - James Gien Wong - https://hyp.is/t8FhpDGAEfC4J7f0NEFujg/medium.com/@gien_SRG/human-cogress-part-2-d6fd075a55c7 - to - Stop Reset Go hypothesis annotations - progress trap - Ronald Wright - https://jonudell.info/h/facet/?max=100&expanded=true&user=stopresetgo&exactTagSearch=true&any=ronald+wright - General - https://jonudell.info/h/facet/?max=100&expanded=true&user=stopresetgo&exactTagSearch=true&any=progress+trap - from - youtube - Planet Critical interview - Samuel Miller MacDonald - The Myth of Progress - https://hyp.is/r-hmFtjKEfCd8odATbINbA/www.youtube.com/watch?v=BEhmWEDkZUQ

Personally, I love this; Image annotations.

This can be used as an effective analysis tool. Visual stimulus is powerful and for many individuals constitutes a deeper connection to fundamental learning. Balanced learning across the three basic modes; written, auditory and visual is implied in academics and the workplace but the reality is that one mode is dominant. Recognizing that mode and enhancing reaps far more advantage than forcing an inferior mode. @Byrnesz

Old book typewriter Underwood Elliott-Fisher (1930), how to type on books, and why (video N°103)<br /> by [[Old Typewriters and Calculators]] on YouTube<br /> accessed on 2025-11-09T09:32:48

Adler, Mortimer J. 1940. “How to Mark a Book.” Saturday Review of Literature 6: 250–52. https://www.unz.com/print/SaturdayRev-1940jul06-00011/ (January 11, 2023).

Annotations: https://via.hypothes.is/https://docdrop.org/download_annotation_doc/Adler---1940---How-to-Mark-a-Book-fehef.pdf

Annotations alternate: https://jonudell.info/h/facet/?user=chrisaldrich&max=100&exactTagSearch=true&expanded=true&url=https%3A%2F%2Fdocdrop.org%2Fdownload_annotation_doc%2FAdler---1940---How-to-Mark-a-Book-fehef.pdf

Prior [.pdf copy]9https://stevenson.ucsc.edu/academics/stevenson-college-core-courses/how-to-mark-a-book-1.pdf): - Annotations https://hypothes.is/users/chrisaldrich?q=url%3Ahttps%3A%2F%2Fstevenson.ucsc.edu%2Facademics%2Fstevenson-college-core-courses%2Fhow-to-mark-a-book-1.pdf<br /> - Alternate annotation link https://jonudell.info/h/facet/?user=chrisaldrich&max=100&exactTagSearch=true&expanded=true&url=https%3A%2F%2Fstevenson.ucsc.edu%2Facademics%2Fstevenson-college-core-courses%2Fhow-to-mark-a-book-1.pdf

Summary

• Marking a book helps in increasing "the most efficient kind of reading."
• The marked (pun intended) difference between physical vs. intellectual ownership of books
• 3 types of book owners:
  • 1. collector of wood pulp and ink
  • 1. one whose read most and dipped into some
  • 1. one who's annotated and sucked the marrow out of them
• Active reading (annotating and staying awake) and engaging deeply, arguing with, and questioning the author is the point of reading.
• A historical record of your active reading allows you to continue the conversation you've had with the author and yourself. (p12)
• Adler's method of reading and marking:
  1. Underlining major points of importance
  2. Vertical lines for emphasis
  3. Marginal marks (stars, asterisks, etc.) (10-20 per book) to indicate the most important statements in conjunction with dogearing these pages for making it easier to find them subsequently
  4. Numbers in the margin to sequence arguments
  5. Page numbers in the margin for linking ideas across pages, ostensibly for juxtaposing them later
  6. Circling key words or phrases (unsaid here, but this is helpful for indexing as well as helping one to come to terms with the author)
  7. Marginal writing for synopsis of sections as well as questions raised by the text; use of endpapers for a personal index of ideas presented chronologically throughout the book
• Objections to marking books:
  • Using scratch pad (or index cards, which he doesn't mention specifically, but which could be implied) so as not to destroy a precious or rare physical copy (this is a repetition from earlier in the article)
  • Marking slows you down. This is part of the point! Slowing down makes you engage with the author and get more out of the text.
  • You can't loan books because they contain your important thoughts which you don't want to give away (and lose the historical record of your thinking). Solution: Simply require friends to buy their own copy.

refer to previous note on all the 'between's

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Gaps -> every part of life seems unfulfilled --> sexual desire unfulfulled

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notes on repetition of 'between'

GAPS * in knowledge of epistemological crisis -> no revelation启示 * action and agency（自主性）-> static/stuck in

notes on repetition of 'between'

GAPS * in knowledge of epistemological crisis -> no revelation启示 * action and agency（自主性）-> static/stuck in

refer to all previous notes on the 'between's

Gaps -> every part of life seems unfulfilled --> sexual desire unfulfulled

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https://github.com/alangrainger/obsidian-air-quotes

An Obsidian plugin that can pull quotes from digital files into specific notes.

Found via: https://forum.obsidian.md/t/using-hypothes-is-to-quickly-place-notes-into-my-digital-notebook/5010/29

for - Jean Gebser - annotations on him from Lisa Maroski's book: - Embracing Paradox, Evolving Language - https://hyp.is/MraNjBtZEfCHI7dtJEkt-w/ipfs.indy0.net/ipfs/bafybeihk6dcr7dfruu65z5e5ze2rkeiydkmgbbpadhyulckm4afnqbtdgy - https://jonudell.info/h/facet/?max=100&expanded=true&user=stopresetgo&exactTagSearch=true&any=jean+gebser

for - progress trap - to - Stop Reset Go hypothesis annotations - progress trap - Ronald Wright - https://jonudell.info/h/facet/?max=100&expanded=true&user=stopresetgo&exactTagSearch=true&any=ronald+wright - General - https://jonudell.info/h/facet/?max=100&expanded=true&user=stopresetgo&exactTagSearch=true&any=progress+trap

for - definition - cogress - Medium article - Cogress - Part 2 - Stop Reset Go - Deep Humanity - James Gien Wong - from - Medium article - Cogress - Part 1 - Stop Reset Go - Deep Humanity - James Gien Wong - https://hyp.is/_Nyg2DF_EfCBeu_iuDroYg/medium.com/@gien_SRG/human-cogress-part-1-5159a575e1c4 - to - Stop Reset Go hypothesis annotations - progress trap - Ronald Wright - https://jonudell.info/h/facet/?max=100&expanded=true&user=stopresetgo&exactTagSearch=true&any=ronald+wright - General - https://jonudell.info/h/facet/?max=100&expanded=true&user=stopresetgo&exactTagSearch=true&any=progress+trap

for - to - book Embracing Paradox, Evolving Language - Lisa argues that language and consciousness are two sides of the same coin - adjacency - Heidegger - Symbolosphere - to - symbolosphere annotations - https://jonudell.info/h/facet/?max=100&expanded=true&user=stopresetgo&exactTagSearch=true&any=Symbolosphere adjacency - between - Heidegger's position on language - the symbolosphere - adjacency relationship - The symbolosphere is an individual or group's world of symbols - Modern humans inhabit the symbolosphere, - in fact, we spend the majority of our lives in the symbolosphere

https://en.wikipedia.org/wiki/S._(Dorst_novel)?

This was mentioned to me at an IndieWebCamp event today.

Seems interesting with respect to the meta portions of books.

Looks like the sort of thing that @remikalir and @anterobot may be interested in.

这篇论文介绍了一个名为ROSCOE的度量标准套件，用于评估逐步骤推理的性能。ROSCOE是一套可解释的、无监督的自动评分系统，旨在改进和扩展之前的文本生成评估指标。该研究通过设计一个推理错误的分类学，并在常用的推理数据集上收集合成和人类评估分数，来评估ROSCOE相对于基线指标的表现

Interstitial journaling predates and may have induced Ryder Carroll's suggestion of using "=" for emotion in Bullet Journaling.

See: https://hypothes.is/a/l12OgFD7Ee-LjAevth_Piw in the piece Carroll mentions interstitial journaling.

Miles, 1905 uses an arrow symbol with a hash on it to indicate a "connecting link between two Sentences or Paragraphs, etc."

It's certainly an early example of what we would now consider a hyperlink. It actively uses a "pointer" in it's incarnation.

Are there earlier examples of these sorts of idea links in the historical record? Surely there were circles and arrows on a contiguous page, but what about links from one place to separate places (possibly using page numbers?) Indexing methods from 11/12C certainly acted as explicit sorts of pointers.

When was the use of the caret first made for indicating the insertion of material?

Eustace Miles has an example from 1905.

Eustace Miles suggests the use of "special marks on cards" (annotations) in the top left corners, though he doesn't provide specific examples of how they might be used in practice. He does mention "The Abbreviations and Marks need be clear only to the Writer [sic] himself. They save ever so much time."

• "X": As contrasted with—
• "Q": Quotation
• Black triangle in corner: important
• Arrow pointing to corner of card: As compared with
• Angled parallel lines in the bottom right corner of card: End of Paragraph (or Chapter).
• Arrow pointing to the corner of card with hash mark: Connecting Link between two Sentences or Paragraphs, etc.
• Upside down V (or caret): An omission, e.g. to be filled in afterwards
• ?: A doubtful point

Footnote 8:

The last edition of Origin published during CD’s lifetime was the 1876 reprint of Origin 6th ed., and had some corrections and additions to the text (Freeman 1977). This edition was produced in a cheaper form than previous ones, with small type and a relatively small page; a ‘gentleman’s’ edition usually had larger type and page size, with wider margins.

Ref: Darwin Correspondence Project, “Letter no. 11918,” accessed on 30 September 2024, https://www.darwinproject.ac.uk/letter/?docId=letters/DCP-LETT-11918.xml

ᔥ[[Richard Carter]] in Mastodon at Sep 23, 2024, 08:20 AM (accessed:: 2024-09-30 01:34:36)

It doesn't seem like he necessarily cared she was leaving and just wanted her gone, and found any excuse to get her off the Google team. Like Buolamwini, she talked to important people to try to get things changed and bettered and it seemed like there wasn't some interest in anything she had to say.

I think there is definitely a connection between the two because they are both struggling with the same problems in their jobs, and as soon as they change skin tones, they are more relevant and people care more about their opinions.

I think throughout this article, they used examples of people that are affected by this and how they look to help people understand they are just as talented as any other human being

for - digital delay stats - Pew Research

summary - That digital decay and link rot are digital facts of life means that annotating information on the page that is relevant for you to preserve is a good practice. - It may appear redundant but if that page disappears in the future, you will be glad you have preserved it in a place accessible to you - in your annotations!

This is related to the video because ChatGPT 3.5 uses the same method to change wording. LLM is a very important thing when using ChatGPT because it is able to make sentences transform into more proper and correct sentences

This is very similar to the ChatGPT video because how ChatGPT produces their answers, is by other peoples answers or searches. Words look for each other to make everything relevant and be put together well, while ChatGPT puts peoples searches together to create one answer.

I expect to learn from this paragraph is why words mean what they mean and how the are used to make sense. Depending on how things are worded, they could mean different things and this paragraph will teach us how to use proper language.

This paragraph will teach us about the languages used when chatgpt was first started and how it was created.

I'm using this quote again because it connects to the video on where ChatGPT models learn how to predict words for their responses. The prediction from ChatGPT leads to complex possibilities and Dobrin connects to this where context is the main reason why AI can make these predictions.

This sentence connects to Dobrin's perspective on ChatGPT limits, arguing whether ChatGPT actually understands the language or just copies answers that sound right. Even in the video, it talks about ChatGPT's model where it creates responses based on context rather that being conscious.

I think this is crazy. It surprises me how many people believe in AI and how many people are actually for it and trying to prove to people that AI is actually helpful and a good resource to use.

I think it's really crazy how fast AI became popular because people have been using it for so long and as soon as student found out it can be a way of cheating, it rapidly grew, and it's cool learning about how AI can help us learn, rather than help us cheat.

I believe I will learn from this paragraph is the background of AI and who and how it was discovered and used throughout the past

In a way wikipedia is another form of AI, all teachers don't like their students getting information from Wikipedia because a lot of it is fake, but AI seems like another step up and finding real true information to find research.

I was very intrigued by this, I didn't know companies have been using AI for information that has been happening around the word. After reading this it now makes sense of how specific the numbers, time, and dates are.

A lot of people tend to be against AI because they think its creepy or flat out wrong, this paragraph is going to help us understand that anyone can us AI for any reason and help colleges and students understand that in certain circumstances AI would be helpful for us.

This paragraph is going to help introduce what AI is an how we can use it for education.

Uhh, I'd imagine "remove" would refer to "bold" annotation.

Otherwise, there can be another "bold" with t < 20, that would be accidentally removed.

Syntactic intent is not preserved.

Adler, Mortimer J. “How to Mark a Book.” Saturday Review of Literature, July 6, 1940.

See also: https://hypothes.is/a/WZWWgnV2EeyFFBshJKbM4A

ownership [of a book]

quote from:<br /> The Booke of the Common Prayer and Administration of the Sacraments (London: 1549), sig. B iiv.

I now know what page notes are. They are annotations without selecting any texts. However, I do not know how to use page notes effectively, or when to use page notes, for me or for my students.

I have known about highlights in Hypothesis.is. Highlights are only visible to myself, but not to others.

However, I have thought about how to use highlights as my own tips for students. Use highlights first while you are reading the article. Highlight potential texts first for later annotation! That way, there is no need to read the article one more time.

This is getting into methods of this study.

Jillian Hess' guess for the origin of King's plagiarism.

It's also possible that he came from a much more oral facing cultural upbringing rather than a dyed-in-the-wool academic one which focused on attribution.

her is some evidence that I am being honest

2023-12-21 BookBridge Talk, 2023. https://www.youtube.com/watch?v=3M-nfWI93nY. Andy Matuschak and Derrek Chow

[[Dan Allosso]] in How to Read, part 2

original source?

it's Benjamin Franklin letter to Miss Stevenson, Wanstead. Craven-street, May 16, 1760.<br /> see: https://hyp.is/HZeDKI3YEeyj9GcNWKX4iA/www.gutenberg.org/files/40236/40236-h/40236-h.htm

https://mitpressonpubpub.mitpress.mit.edu/pub/syyor4ra/release/1?readingCollection=31668090

From Chapter 3 of Remi Kalir and Antero Garcia's book Annotation.

I've referenced this image so many times, I ought to finally bookmark it, right?

Ted Nelson shows a similar one when talking about Project Xanadu and the importance of parallel texts.

https://medium.com/workings/obsidian-properties-meets-sidenotes-1b46a25d8be

A note taking tool discussed by [[Bastien Guerry]] at I Annotate 2021.

“You don't read without marking; you can't mark without reading.” —Kori Stamper

Delmore Schwartz' heavily annotated copy of James Joyce's Finnegans Wake; complete work digitized

https://collections.library.yale.edu/catalog/10646994

https://archaeologyofreading.org/ The Archaeology of Reading

https://blogs.bard.edu/arendtcollection/

cc: remikalir

https://www.reddit.com/r/books/comments/17pitv9/when_does_annotating_books_become_a_distraction/

This entire thread is a fascinating sample look at the state of annotation with respect to reading practices.

via https://www.reddit.com/r/books/comments/17pitv9/comment/k86tusz/?utm_source=reddit&utm_medium=web2x&context=3

reply to u/Low-Appointment-2906 at https://www.reddit.com/r/books/comments/17pitv9/when_does_annotating_books_become_a_distraction/

Through the middle ages, bookmakers would not only leave significant margins for readers to annotate, but they also illuminated books and included drolleries which readers in the know would use in conjunction with the arts of memory (from rhetoric) to memorize portions of texts more easily. I strongly suspect this isn't what booktokkers are doing; their practice is likely more like the sorts of decorative #ProductivityPorn one sees in the Bullet journal and journaling spaces. It's performative content creation.

Those interested in refining their practices of "reading with a pen in hand", continuing the "great conversation" or having "conversations with their texts" might profitably start with Mortimer J. Adler's essay: “How to Mark a Book” (Saturday Review of Literature, July 6, 1941). In his 1975 KCET series How to Read a Book, which was based on their book of the same name, Adler mentioned to Charles Van Doren that he would buy new copies of books so he could re-annotate them without being distracted by his older annotations.

Some have solved the problem of distracting annotations by interleaving their books so they've got lots of blank space to write their notes. It's a rarer practice now, but some publishers still print Bibles with blank pages every other page for this practice. Others put their annotations and notes into commonplace books or on index cards for their card index/zettelkasten.

As some have mentioned, friends and lovers through time have shared books with annotations as a way of sharing their thoughts. George Custer and his wife Elizabeth did this with Tennyson.

If you're interested in annotating digitally online, perhaps check out Hypothes.is where I've seen teachers and students using social annotation to read and make sense of books [example]. I've also seen groups of people use this tool for hosting online book groups/clubs.

If you're in it for fun, you might appreciate:

• https://archaeologyofreading.org/
• https://booktraces-public.lib.virginia.edu/
• My digital annotations on annotation

And those wishing to delve more deeply into the history and power of annotation might look at: Kalir, Remi H., and Antero Garcia. Annotation. The MIT Press Essential Knowledge Series. MIT Press, 2019. https://mitpressonpubpub.mitpress.mit.edu/annotation.

Good luck annotating! 📝

love "raucous conversation"!

Thomas Jefferson wrote the names of the previously anonymous authors of The Federalist next to their essays in his personal copy.

https://chantalmb.github.io/MRE-MitM-2023/

Found via Shawn Graham @electricarchaeo@scholar.social

Folks, I am so pleased to share that Chantal Brousseau has won the University Medal for Outstanding Graduate Work at the Master's Level for her major research project 'Metadata in the Margins - Reshaping Archives as Data through Early Modern Marginalia' > https://chantalmb.github.io/MRE-MitM-2023/

Just a tremendous person to work with; I've been lucky to work with her. So pleased! #histodons #dh https://hcommons.social/@electricarchaeo@scholar.social/111292052630790110

cc: remikalir

reply to u/Sensitive-Binding at https://www.reddit.com/r/antinet/comments/17ck5la/what_is_it_with_index_cards/

Some of it may involve the difference in available space versus other forms of writing on larger pages of paper. Similarly, many find that there is less pressure to write something short on Twitter or similar social media platforms because there is less space in the user interface that your mind feels the need to fill up. One can become paralyzed by looking at the larger open space on a platform like WordPress with the need to feel like they should write more.

With index cards you fill one up easily enough, and if there's more, you just grab another card and repeat.

cross reference with Fermat's Last Theorem being easier to suggest in a margin than actually writing it out in full.

Example: Hypothesis Plug In.

http://annotatingausten.sfsuenglishdh.net/

Three AI Chatbots, Two Books, and One Weird Annotation Experiment by Remi Kalir on September 29, 2023 https://remikalir.com/blog/three-ai-chatbots-two-books-and-one-weird-annotation-experiment/

An interesting divergent take on writing in library books...