216 Matching Annotations
  1. Nov 2024
    1. four things

      for - suggestions - how to end US hegemony for a global fair trade system - needed to re-establish global cooperation - Yanis Varoufakis - Yanis Varoufakis four on below to discuss four different suggestions of how China can support global cooperation to emerge

    1. Hi friends! I received a vintage teal blue SCM Smith Corona "Skyriter" typewriter. It is awesome, but it does not have the original spools. I ordered an expensive original ribbon from eBay, but it was totally dried out. Then I ordered an inexpensive "universal" (2") spool from Amazon that didn't fit in my machine. Does anyone have recommendations of new, small spool (1 5/8") ribbons that tend to be reliably inky? I am located in Canada and getting tired of paying import costs on stuff that doesn't work. Thanks in advance!

      reply to u/actualwoey at https://old.reddit.com/r/typewriters/comments/1gqhied/recommendations_for_reliable_new_small_spool_1_58/

      You could see if a local repair shop is parting out a machine or has spools that would work for you. iirc the Corona Zephyr, Skyriter, and the later versions of the Corsair all used that smaller spool size, usually described as 1 5/8" or 1 2/3". https://site.xavier.edu/polt/typewriters/tw-repair.html Once you've got the correct sized spools, you can wind your Amazon ribbon onto them, but you'll likely have to trim it down to fit. (2" spools usually have 16 yards of ribbon while the 1 5/8" accommodate about 12 yards.)

      If you can't come up with original metal spools to respool your 1/2" ribbon onto, you can try https://www.ribbonsunlimited.com/category-s/12779.htm which will sell you both in one go.

      Some other ribbon options: https://site.xavier.edu/polt/typewriters/tw-faq.html#q1. I've had good luck buying bulk ribbon from both Baco Ribbon and Fine Line.

      I've heard some have successfully re-juvenated old ribbon by spraying it (unspooled into a box) with WD-40 or glycerine to re-wet it and then respooling it.

  2. Oct 2024
  3. Sep 2024
    1. Typewriters? In 2024? Are You Nuts? by Jesse M. Slater for [[Raconteur Press]]

      A short, but relatively solid typewriter 101 story for someone looking for a distraction-free writing machine. Certainly not completist, but enough to get your toes wet.

      Slater uses his typewriter for a first draft, then edits the second draft as he re-types it into his computer to have a digital copy for further editing and distribution.

    1. for - Federico Faggin (FF) - analytic idealism - consciousness - Deep Humanity

      summary - This is an good talk that introduces Federico Faggin's (FF) ideas about consciousness from the perspective of analytic idealism, the idea that consciousness is the most fundamental aspect of reality and that materialism is an epiphenomena of consciousness, not the other way around - Bernado Kastrup's organization, Essentia Foundation invited FF to the Netherlands to give a talking tour of his new - book "Irreducible" - https://www.collectiveinkbooks.com/essentia-books/our-books/irreducible-consciousness-life-computers-human-nature - and they visited the prestigous semiconductor design company ASML' facilities, - https://www.asml.com/en - where this insightful talk was delivered - FF reconciles scientific explanation with the hard problem of consciousness and our ordinary, everyday experience of consciousness - FF's theory offers - a good western, science-based explanatory framework that is consistent with - the experiential and theoretical framework from the east - from - Tibetan Buddhist - Zen Buddhist - Vedic - and other ancient ideas of emptiness<br /> - This framing heals the divide between science and religion that has created a meaning crisis in modernity - and by so doing, also addresses a core issue of the meaning crisis - mortality salience

  4. Aug 2024
    1. what we do is we use language we squeeze it down to a to a simple low bandwidth message you will have to re-expand and and reinterpret that message

      for - squeezing down and re-expanding - Michael Levin

  5. Jul 2024
    1. The worst thing for stone – and for bricks, come to that – is for them to be bedded, jointed or rendered with hard cement mortars.

      for - sustainable building - cement mortar is the worst thing for re-using bricks

    1. most of the great religions in the world have been attempts to to restrain or reform uh human nature or at least uh channel our worst impulses into something 01:10:48 more productive or higher something loftier um and in this this is exactly what we need here it's something that will create a form of altruism which doesn't only extend to people we see around us now but extends 01:11:00 to the future generations

      for - rapid whole system change - need for something that will create a new form of altruism - Ronald Wright - transition - requires an experience of re-awakening transition - need for a new religion? Deep Humanity?

      comment 10 July 2024 - Deep Humanity is our attempt at this. It is not a religion, however. It is humanity, but in the deepest sense, so it is accessible to anyone in our species. Our tagline has been - Rekindling wonder in an age of crisis - However, this morning an adjacency occurred:

      adjacency - between - familiarity - wonder - adjacency relationship - Familiarity hides wonder - Richard Dawkins said: - There is an anaesthetic of familiarity, - a sedative of ordinariness - which dulls the senses and hides the wonder of existence. - For those of us not gifted in poetry, - it is at least worth while from time to time - making an effort to shake off the anaesthetic. - What is the best way of countering the sluggish habitutation brought about by our gradual crawl from babyhood? - We can't actually fly to another planet. - But we can recapture that sense of having just tumbled out to life on a new world - by looking at our own world in unfamiliar ways. - That is, when a type of experience becomes familiar through repeated sensory episodes, - we lose the feeling of wonder we had when we initially experienced it - It's much like visiting a place for the very first time. We are struck with a sense of wonder because everything is unpredictable, in a safe way. We have no idea what's around the next corner. It's a surprise. - However, once we live there, and have traced that route hundreds of times, we have transformed that first magical experience into mundane experience. - So it is with everything that makes us human, with all the foundational things about reality that we learned from the moment we were born. - They have all become jaded. We've forgotten the awe of those first experiences in this reality: - our first experience of our basic senses - our first breath of air, instead of amniotic fluid - our first integration of multiple sensory experiences into a cohesive whole - the birth of objectification - the very first application of objectification to form the object we called mOTHER - the Most significant OTHER - our first encounter with the integration of multiple sensory stimuli associated with each object we construct - our first encounter with auditory human, speech symbols - our first experience with object continuity - how objects still exist even if they disappear from view momentarily - do we remember freaking out when mOTHER disappeared from view momentarily? - our first ability to communicate with mOTHER through speech symbols - our first encounter with ability to control our bodies through our own volition - our first encounter with gravity, the pull towards the ground - our first encounter with a large bright sphere suspended in the sky - our first encounter with perspective, how objects change size in our field of view as they get nearer or farer - etc... - What's missing now, is that we have repeated all these experiences so many times, that the feeling of awe no longer emerges with life - To generate awe, the repertoire of existing experiences is insufficient - now we have to create NEW experiences, we have to create novelty - Mortality Salience can help jolt us out of this fixation on novelty, and remind us of the sacred that is already here all the time - For, what happens at the time of death? All the constructions we have taken for granted in life disappear all at once, or perhaps some before others - Hence, we begin to re-experience them as relative, as constructions, and not absolutes - All living organisms have their own unique umwelt - These umwelts are all expressions of the sacred, sensing itself in different ways

      • What is required is a kind of awakening, or re-awakening
      • When religions do their job, it gives us a framework to engage in a shared sense of the sacred, of wonder in the mundane
      • In a sense, Deep Humanity is identifying that most vital commonality in all religions and seeing all their diverse intersectionalities in simply being deeply human
      • We awakened once, when we were born into the world
        • then we fell asleep through the dream of familiarity
      • Now, we have to collectively re-awaken to the wonder we all experienced in that initial awakening experience as newborns
  6. May 2024
    1. Any selective disclosure is potentially ineffective unless per-formed within the confines of a contractually protected disclosure that imposes an incentive onthe disclosee (verifier) to protect that disclosure (counter-incentive against the exploitation ofthat discloser).
  7. Jan 2024
  8. Aug 2023
    1. contacting your city council members running for office yourself donating to projects like black space and getting involved in zoning board meetings that could help change the density and makeup of the 00:20:08 communities where you live
      • for: zoning, city council, re-zoning, low carbon city, walkable city
  9. Jul 2023
  10. Jun 2023
  11. ivanov-petrov.livejournal.com ivanov-petrov.livejournal.com
    1. Всегда был тот, кто говорил с травой, с землей, с колючками, кто разводил руки, касался осторожно семян, острых ростков, зеленых, желтеющих, выцветших добела, до бумажной хрупкости, до пыли почти. С теми, кто был травой, кто ею стал, кто никогда не хотел, кто и не был против.Кто никогда не выбирал, с кем ему говорить. Кому трава отвечала.
    1. n doing so, language education programs have erased all tracesof heteroglossia in language (Bailey 2007), upholding the standardized versions of named languagestaught and valued in school, instead of valuing and recognizing the complex linguistic practices ofmultilingual speakers. But this traditional view of multilingualism has started to show fissures. Nextwe discuss how and why we are facing these ‘cracks’ in our conception of multilingualism andhow it is viewed and used in school

      the idea of multiling separatedly

  12. Mar 2023
    1. We find that meeting such access needs for the billions in poverty may lead to crossing ESBs unless resources are reallocated from the rich to the poor28, in line with limitarian and sufficientarian justice37,73.
      • Comment
      • The transformation of the economically wealthy will be critical to the future of civilization
  13. Feb 2023
  14. www.edwinwenink.xyz www.edwinwenink.xyz
    1. Here’s a basic hermeneutic insight for you: interpretation requires a form of application which renews the interpretandum by engaging it in a new context. Yes, “something in it anarchives” itself, but that’s also the seed for the old to enter into something new and to stay “alive”.
    1. Only then do I start writing. Compared with the labour of making, sorting and arranging notes, this is a relatively speedy business. But it is followed by a much more time-consuming task, that of travelling round the libraries to check the references in my footnotes, only too many of which, thanks to poor handwriting, carelessness and an innate tendency to ‘improve’ what I have read, turn out to be either slightly wrong or taken out of context.That one hit a little close to home. lol.

      We should also acknowledge that when revisiting some of our references again later, we're doing so with a dramatically increased knowledge and context of a particular problem which we may not have had when we first read a piece or took the notes.

      Not many here are writing or talking about these small sorts of insights into learning and writing or generating new work. Perhaps we should do more to acknowledge this hermeneutic cycle in our work?


      reply to u/stjeromeslibido at https://www.reddit.com/r/Zettelkasten/comments/10wj6tv/comment/j7uexbk/?utm_source=reddit&utm_medium=web2x&context=3

  15. Nov 2022
    1. Έδωσε,πράγματι, τη διαταγή της προελάσεως πέραν της ζώνης τηςΣμύρνης (π.χ. στο Ουσάκ), αλλά το έκανε για μια πολύπεριορισμένη περιοχή κοντά στα όρια της ζώνης της Σμύρνης,εξυπηρετώντας και τις ανάγκες αμύνης των συμμαχικώνδυνάμεων στην ευρύτερη περιοχή.

      Για τις συνετές στρατιωτικές του επιλογές.

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  16. Oct 2022
    1. They were adding social structures and context to the data. Basically adding social software design principles to a large volume of data.

      After letting professionals in a company have access to their internal BI data, they made it re-usable for themselves by -adding social structures (iirc indicating past and present people, depts etc., curating it for specific colleagues, forming subgroups around parts of the data) -adding context (iirc linking it to ongoing work, and external developments, adding info on data origin) Thus they started socially filtering the data, with the employee network as social network [[Social netwerk als filter 20060930194648]].

    2. they had given a number of their professionals access to their business intelligence data. Because they were gathering so much data nobody really looked at for lack of good questions to ask of the dataset. The professionals put the data to good use, because they could formulate the right questions.

      Most data in a company is collected for a single purpose (indicators, reporting, marketing). Companies usually don't look at how that data about themselves might be re-used by themselves. Vgl [[Data wat de overheid doet 20141013110101]] where I described this same effect for the public sector (based on work for the Court of Audit, not tying it back to this here. n:: re-use company internal data

  17. Sep 2022
  18. ivanov-petrov.livejournal.com ivanov-petrov.livejournal.com
    1. Колыбельная "памяти всех"Дело прошлое – любили, не любили,насажали опечаток на могиле,стали книгами, рассказами, рекой.Позабытые, ненужные, не в моде,баю-баюшки, они уже уходят,помаши им на прощание рукой.Дело прошлое – хранили, предавали,все разбросанное бережно собрали,потащили на совсем не страшный суд...От рождения до смерти полстраницы.Баю-баюшки, да что ж тебе не спится?Засыпай, иначе в сводки не внесут.Дело прошлое – любили, как умели,до оскомины друг другу надоели,расставались, целовались, всё в бреду.Поселились в фотографиях потертых.Баю-баюшки, дитя, не бойся мертвых.Не обидят. Не обманут. Не придут.
  19. Aug 2022
  20. Jul 2022
    1. The richest 10 percent accounted for over half (52 percent) of the emissions added to the atmosphere between 1990 and 2015. The richest one percent were responsible for 15 percent of emissions during this time – more than all the citizens of the EU and more than twice that of the poorest half of humanity (7 percent).

      This is a key leverage point strategy for Stop Reset Go for Rapid Whole System Change (RWSC) strategy. As argued by Kevin Anderson https://youtu.be/mBtehlDpLlU, the wealthy are a crucial subculture to target and success can lead to big decarbonization payoffs.

      The key is to leverage what contemplative practitioners and happiness studies both reveal - after reaching a specific level of material needs being met, which is achievable for staying within planetary boundaries, we don’t need any more material consumption to be happy. We need an anti-money song: https://youtu.be/_awAH-JJx1kamd and enliven Martin Luther King Junior’s quote aspirational: the only time to look down at another person is to give them a hand up. Educate the elites on the critical role they now play to solve the double problem of i equality and runaway carbon emissions.

  21. Jun 2022
    1. • Write down ideas for next steps: At the end of a worksession, write down what you think the next steps could be forthe next one.• Write down the current status: This could include your currentbiggest challenge, most important open question, or futureroadblocks you expect.• Write down any details you have in mind that are likely tobe forgotten once you step away: Such as details about thecharacters in your story, the pitfalls of the event you’re planning,or the subtle considerations of the product you’re designing.• Write out your intention for the next work session: Set anintention for what you plan on tackling next, the problem youintend to solve, or a certain milestone you want to reach.

      A lot of this is geared toward the work of re-contextualizing one's work and projects.

      Why do all this extra work instead of frontloading it? Here again is an example of more work in comparison to zettelkasten...

  22. May 2022
    1. For one test, the researchers trained the neural network with data from an unidentified mobile phone service that detailed 43,606 subscribers’ interactions over 14 weeks. This data included each interaction’s date, time, duration, type (call or text), the pseudonyms of the involved parties and who initiated the communication.

      Graph of Phone Calls/Texts

      One of the tests involved the researcher creating a directed graph of user calls/texts including timestamp, type of interaction (call versus text), and duration. Just based on the pattern of interaction, the AI could be fed the graph of a known individual and be spotted in the anonymized dataset about 15% of the time. Adding the second derivative interactions into the search graph increased the positive result to just over 50%.

  23. Apr 2022
    1. instructors and experts must also become more legible models. This can beaccomplished through what philosopher Karsten Stueber calls “re-enactiveempathy”: an appreciation of the challenges confronting the novice that isproduced by reenacting what it was like to have once been a beginner oneself.
  24. Feb 2022
  25. Jan 2022
  26. Oct 2021
    1. w/ Jurgis Didžiulis, Mark Smith, Amanda Joy Ravenhill, Turquoise Sound, Tamas David-Barrett — 📡 Re&Co RADIO | a weekly transmission of regenerative thinking & musical co-creation |cross-disciplinary conversations, synesthesic jams, and other fluxus | 📡 KPCR.fm 🔴rec
    1. Yarrow Kraner

      Hatch

      Yarrow is the Founder of HATCH and H360.ai, is an Aspen Institute Fellow, RSA Fellow, and named 2015 top 100 creatives in the U.S. by Origins. He is a pioneer of social networking and has been building communities for twenty years.

      Shared by Mark Smith and Jurgis Didžiulis. We were chatting in the RE & CO Radio soundcheck room just before the live event in Clubhouse.

    1. Jurgis Pranas Didžiulis Valencia (born 5 November 1979 in Bogotá , Colombia ) is a performer, song and music author, producer, public figure and activist.
    1. “The real problem of humanity is the following: we have paleolithic emotions; medieval institutions; and god-like technology.

      Quoted by Amanda Joy Ravenhill on RE & CO Radio, Wednesday, October 13, 2021.

      This leads to a sense of learned hopelessness: Things are worse than you imagined, and there is nothing you can do about it.

      But Buckminster Fuller said, “We are called to be the architects of the future, not its victims.”

  27. Aug 2021
  28. Jun 2021
    1. Well, there are a lot of reasons, with the main reason being that I am empathetic to what is happening out there and I agree with many other people that we should re-examine our choice of words to make the industry more inclusive.
  29. Apr 2021
    1. Über einen Bericht der Swiss Re, der die globale Erhitzung als Problem für das Wachstum ansieht. Danach würde eine Temperatursteigerung um 2,3° bis 2050 in diesem Jahr zu einer Minderung des globalen Wachstums um 23 Trillionen USD führen. Die armen Länder wären davon am stärksten betroffen. Es werden auch Szenarien mit größeren Temperatursteigerungen durchgerechnet. Der Bericht steht in der Nachfolge des Stern-Reports, in dem zum ersten Mal detailliert versucht wurde, die wirtschaftlichen Kosten der Klimakrise zu berechnen. Climate Change Could Cut World Economy by $23 Trillion in 2050 - The New York Times

    1. the term historical revisionism identifies the re-interpretation of a historical account.[1] It usually involves challenging the orthodox (established, accepted or traditional) views held by professional scholars about an historical event or time-span or phenomenon, introducing contrary evidence, or reinterpreting the motivations and decisions of the people involved.
  30. Mar 2021
    1. o put it in the language of psy­chology, there are limits on the number of distinct concepts which we can manipulate cognitively at any one time, and we. are therefore forced, if we wish to get a view of the whole problem, to re-encode these items.1
  31. Feb 2021
    1. Another HD wallet solution to generate privacy is a so-called merge and re-split operation. In this example, several entities anonymously submit new addresses to a smart contract. The contract collects the same amount from each party, let's say it's 100 bitcoins each. Then the contract re-deploys the amount to the new addresses.

      workaround to avoid full trace with attribution

  32. Nov 2020
    1. There is no rerender, when you call listen, then all scroll events will warn on chrome. See this entry from svelte: breaking the web

      Even the author of this library forgot this about Svelte?? :) (Or maybe he didn't and this response misunderstood/falsely assumed that he had.)

    1. If you rely on any external dependencies (files required in a preprocessor for example) you might want to watch these files for changes and re-run svelte compile. Webpack allows loader dependencies to trigger a recompile. svelte-loader exposes this API via options.externalDependencies.
  33. Oct 2020
    1. The original promise of React was that you could re-render your entire app on every single state change without worrying about performance. In practice, I don’t think that’s turned out to be accurate. If it was, there’d be no need for optimizations like shouldComponentUpdate (which is a way of telling React when it can safely skip a component)
  34. Sep 2020
    1. useField() returns FieldRenderProps. It will manage the rerendering of any component you use it in, i.e. the component will only rerender if the field state subscribed to via useField() changes.
    1. Since you often want to do calculations based on state, Svelte also has the “reactive declaration” symbol, $:. It’s like a let declaration, but whenever any variable referenced in the expression — count in this case — is updated, the expression is re-run, the new variable’s value is updated, and the component is re-rendered.
    2. The heart of Svelte’s magic is “reactivity”. Every let declaration sets up a listener, where any time the variable is assigned to, the change triggers a render of the component. So when the increment function calls count++, the component will re-render, which will update the value shown to the user by Count: {count}.
    1. To change component state and trigger a re-render, just assign to a locally declared variable.
    1. repetition of yes all leads up to the final yes to marriage. the lack of punctuation also makes the whole thing read as if it's being said very quickly, as if a lot of thoughts are happening all at once.

    1. losing

      the repetition of the many forms of the verb "to lose" highlights the theme of loss throughout the poem without the poet having to explicitly tell the reader what it is about

  35. Aug 2020
    1. In the two years that I've been working with React professionally, I've never come to a point where I needed to force a re-render. I encourage you to read the article from the beginning if that's what you're here for because usually there's a better way of dealing with React components that aren't updating.
    1. Cajner, T., Crane, L. D., Decker, R. A., Grigsby, J., Hamins-Puertolas, A., Hurst, E., Kurz, C., & Yildirmaz, A. (2020). The U.S. Labor Market during the Beginning of the Pandemic Recession (Working Paper No. 27159; Working Paper Series). National Bureau of Economic Research. https://doi.org/10.3386/w27159

  36. Jul 2020
  37. Jun 2020
  38. May 2020
  39. Jan 2020
  40. Jul 2019
    1. REFERENCES
    2. Conclusion
    3. ROS ASSAY
    4. In vitro cytotoxic activity of methanolic extract of N. sativafrom different germination phasesduringSRB assay
    5. n vitro cytotoxic activity of methanolic extract of N. sativafrom different germination phasesduringMTT assay
    1. Relative distribution of virulence genes among V. parahaemolyticusfrom Cochin estuary, shrimp farm and sea food
    2. Prevalence of type III secretion system genes amongV. parahaemolyticusfrom Cochin estuary, shrimp farm and seafood
    3. Prevalence of tdhand trhgenes among V. parahaemolyticusfrom Cochin estuary, shrimp farm and seafood
    4. Relative prevalence of extracellular virulence factors among Vibriofrom Cochin estuary, shrimp farm and seafood
    5. Prevalence of extracellular virulence factors in Vibriofrom seafood
    6. Prevalence of extracellular virulence factors in Vibriofrom shrimp farm
    7. Prevalence of extracellular virulence factors in Vibriofrom Cochin estuary
    1. Plasmid curing of Vibriofrom Cochin estuary,shrimp farms and seafood
    2. Plasmid profiles among Vibriofrom Cochin estuary, shrimp farms and seafood
    3. Distribution of antibiotic resistance genes in Vibriofrom Cochin estuary, shrimp farm and seafood
    4. MAR indexingand antibiotic resistance pattern amon
    5. Relative antibiotic resistance amongVibrioisolated from Cochin estuary, shrimp farm and seafood
    6. Antibiotic resistance among Vibriofrom seafood
    7. Antibiotic resistance amongVibriofrom shrimp farm
    8. Antibiotic resistance amongVibriofrom Cochin estu
    9. Antibiotic resistance amongVibrio
    10. Plasmid curing of Vibriofrom Cochin estuary,shrimp farms and seafood
    11. Distribution of antibiotic resistance genes in Vibriofrom Cochin estuary, shrimp farm and seafood
    12. MAR indexingand antibiotic resistance pattern amon
    13. Relative antibiotic resistance amongVibrioisolated from Cochin estuary, shrimp farm and seafood
    14. Antibiotic resistance among Vibriofrom seafood
    15. Antibiotic resistance amongVibriofrom shrimp fa
    16. Antibiotic resistance amongVibriofrom Cochin estu
    17. Antibiotic resistance amongVibrio
    1. Genbank accession numbers
    2. Seasonal variation in the diversity and distribution of Vibrioin Cochin estuary
    3. Relative diversity and distribution of Vibrioin the water and sediment of Cochin estuary
    4. Species level identification and distribution of Vibriospecies in Cochin estuary
    5. Environmental parameters
  41. sg.inflibnet.ac.in sg.inflibnet.ac.in
    1. Active site identification, metal detection and interaction of Dof domain structure
    2. Superposition of the Dof domain with predicted 3D structure
    3. Validation of the predicted 3D structure
    4. Tertiary structural prediction
    5. Secondary structural prediction
    6. Secondary and tertiary structure prediction of SbDof proteins o
    7. Cis-regulatory elements analysis
    8. Motif analysis
    9. Evolutionary relationships of sorghum, rice and Arabidopsis with respect to Dofgene family
    10. Gene structure prediction
    11. Phylogenetic relationships among Dofproteins of sorghum
    12. Chromosomal locations
    13. In silico prediction of Dof gene family of sorghum
    14. Genome wide identification and in silico characterization of Dof gene family of sorghum
    15. Phylogenetic and motif analysi
    16. In silico characterization of cloned Dof gene
    17. Phylogenetic and motif analysis of sequenced Dof domains
    18. In silico characterization of sequenced Dof domains of cereal
    19. Sequencing of Dof domain and gene
    20. Cloning of Dof genes of sorghum using pBSK vector
    21. Cloning of Dof domain and Dof genes using pGEM-T Easy
    22. Gel elution of PCR products
    23. PCR based cloning, sequencing and in silico characterization of Dof domain and Dofgenes of cereals and millet
    24. Comparative analysis of cereals and millets based on banding patterns generated by Dof domain and Dof genes-specific primers
    25. PCR amplification of Dof gene
    26. PCR amplification of Dofdomain
    27. PCR amplification of Dof domain and Dof genes
    28. Primer designing for PCR amplification of Dof domain and Do
    29. Isolation, purification and quantification of genomic DNA
    30. PCR amplification of Dof domains/genes and studying the polymorphisms generated by different sets of primers for cereals and millets
    1. Estimation of antibody response in rLdADHT+BCG vaccinated hamsters
    2. Estimation of mRNA cytokines in rLdADHT+BCG vaccinated hamsters as well as in control groups
    3. Immunological Responses (DTH, mitogenic and Leishmania-specific cellular responses)
    4. Assessment of parasitic burden in hamsters vaccinated with rLdADHT+BCG and challenged with L. donovan
    1. The recombinant Th1 stimulatory proteins (rLdADHT, and rLdTPR,) induced lymphoproliferative and NO responses in normal/infected/cured hamst
    1. The table 6.1 gives the mixing probabilities and the associated parametricvalues fork(number of components) = 2,3, and 4. It may be noted thatthe Log likelihood value is smaller fork= 4 (the results fork= 5 , 6 etc.are not better than that fork= 4 and hence are not given here). The fourcomponents Poisson Mixture model is given in table 6.2. It may be notedthat 58% of wards may have higher incidence/relative risk and the remainingwards have lesser/lower incidence for the Cancer disease. We computed theposterior probability for each component for each ward (see table 6.3). Eachward is assigned to a particular component so that the posterior probability islarger. These results are also given in table 6.3 Finally we present Choroplethmaps based on those results
    1. We have analysed the Cancer data of patients in 155 wards of Chennai Cor-poration by the above described method. As preliminary analyses, we havecreated the Choropleth maps for Observed counts, Population of wards, ex-pected counts for patients and SMR's.The Choropleth map for the observed counts Figure 5.2 does not show anypattern. But the Choropleth map for the expected counts Figure: 5.4 indi-cate that the inner regions of the Chennai Corporations have lower expectedcounts and the regions along the border have larger counts of patients. As ameasure of spatial heterogeneity we have computed PSH= 0:7108:Hence ofthe total spatial random variation, nearly 71% is due to spatial heterogene-ity and the remaining 28:92% is due to Poisson variation. Thus the spatialvariation is present in the data.The Choropleth map for Empirical Bayes smoothed rates Figure 5.5 re-veals that only 13 sub regions have high risk values. The wards with numbers53, 64, 67, 70, 78, 93, 100, 103, 110, 117, 122, 147 and 151 have high riskvalues. Though this information could be used by the health managers toconcentrate their work on these regions, one can look for additional covariatesin these regions for further study
  42. Jun 2019
    1. Dominance of regulatory transitional B cellsand lower memory B cells in HBsAgpositive compared to negative newborns
    2. Post vaccination enhanced expression of activation marker CD69 and Chemokine receptor CCR5 on memory B cells in HBV positive newborns
    3. Post-vaccination declination of Transitional B cell population and increase in memory B cells in HBV positive newborns
    4. Increased Chemokine and Toll like receptor on T cells after vaccination in HBV positive newborns.
    5. Vaccination improved the Chemokine receptor CCR1, CCR3, CCR9 and Toll like receptor TLR2, TLR4 and TLR9 expression in HBsAgpositive newborns compared to healthy newborns.
    6. T cell frequencies(Post vaccination response)
    7. Post-vaccination immune responses in newborns
    8. IFN γ production by CD8 T cells upon stimulation with PMA and viral peptides
    9. Decreased CD3 ζ chain expression on CD8 T cells in HBsAgpositive newborns
    10. Phenotypic and Functional Characterization of CD8 T cells in cord blood
    11. Cord Blood immune profiles of HBV positive newborns at birth(Cord blood vs. peripheral blood)
    12. Pre-vaccination:Lower Chemokine and Toll like receptor expression in HBsAgpositive newborns:
    13. T cell phenotypic distribution in HBsAgPositive, HBsAgNegative from HBsAg positive mothers and healthy newborns.
    14. Clinical characteristics of the subjects
    15. CD107a expression (marker of cytotoxicity)