Businesses are rapidly relying on artificial intelligence to enhance user experiences, automate processes, and gain competitive advantages. However, understanding AI app development cost remains one of the biggest challenges for companies planning to create artificial intelligence app solutions.
Explore the key factors influencing AI app development cost in 2025. Learn how app complexity, features, and tech stack impact your budget for smart AI solutions.
ASP.NET API of AutoCAD is a part of the larger set of APIs from Autodesk. To start working with AutoCAD API integration you need to have a good understanding of all the programming principles of .NET and the object model of AutoCAD.
Explore the key factors influencing .NET development costs, from project complexity to developer expertise. Learn how to estimate the cost of building .NET applications, including enterprise solutions and web apps. Get insights into budget planning, hiring .NET developers, and cost-effective strategies for your project.
4.3 Geopolitics- study of the effects of geography on politics and relations among states.<br /> Territoriality - a willingness by a person or group of people to defend space they claim. A people's connection to a particular piece of land.
Neocolonialism- Process which powerful countries attempt to control weaker countries because of economic or cultural pressures. Control was indirectly exerted over developing countries. Ex. Transnational corporations based in European countries continued to control the extractions of natural resources through mining and the export of natural resources
relaxed safer sex practices after the advent of potent HIV combination therapies, increased methamphetamine use drove riskier behavior and an explosion of online dating made it hard to track and test sexual partners
Since then, funding has remained anemic.
she feared catching the coronavirus and skipped prenatal care.
The decisions are often politically driven and can be detached from actual health needs.
Zhang Qian's journey provided the Chinese with valuable information about the lands and peoples of Central Asia, and his report to Emperor Wudi helped to establish trade networks between China and Central Asia.
diplomatic mission to the Yuezhi nomads in modern-day Uzbekistan, led by an official named Zhang Qian. Zhang Qian's journey was a significant one, as it marked the beginning of Chinese travel to Central Asia.
Chinese princesses were sent to marry the Xiongnu leaders as part of the treaty agreement.
Peace and Friendship" accords, established a framework for relations between the Chinese and the Xiongnu that lasted for about 150 years.
he first emperor of the Han dynasty, Liu Bang, was a former official who had once been in charge of policing a section of the imperial highway system.
ACTUAL HAN
imperial courier network
imperial tribute system motivated travel for other purposes as the infrastructure was there
The construction of a network of five great tree-lined 'fast roads' that converged on his capital at Xianyang linked the city to the eastern, southern, and northern regions of the empire.
The Chinese took an important lead in promoting travel, with formal state policy involved in promoting travel
Needs better sourcing, but
Henry Dreyfuss added crinkle paint to his Royal Quiet De Luxe typewriter design to diffuse reflected light so that typists who worked at their machines all day wouldn't have headaches from the glare reflecting off the fronts of their machines.
The challenge and the problem is that emergency to our neural ancestral wiring meant a saber toothed tiger or something like that. And these risks are complex. They're in the future. They're abstract. There are no easy solutions. the famous people on TV aren't talking about them. so it's, really difficult.
for - planetary emergency - psychological factors - the 5 Ds
planetary emergency - psychological factors - the 5 Ds - Nate brings up the psychological challenges. These are summarized nicely by Per Espen Stokes interview on the Al Jazeera documentary below, where he discusses the 5 Ds:
reference - Per Espen Stokes psychological factors that make climate action difficult - the 5 Ds - https://hyp.is/UgWKRlNcEe-sPqcIvC-9Aw/www.youtube.com/watch?v=fqXys5VluIQ
Link to academic resources, as appropriate (such as Office of Disability Services, Learnin
linking to student resources
The content needs to be grounded instated course learning goals and be organized into content segments/modules.a. Structure the course to support the learning goals.b. Arrange the course content in a linear, logical structure, and organize the content intomanageable segments/modules.c. Use consistent organizational structure, color scheme, and textual components throughoutthe course to help students navigate the course.d. Provide course materials (graphics, media, documents, etc.) in accessible formats (ADACompliance for Online Course Design).
Course organization
ate overall course learning goals clearly and measurably
Learning objectives stated
For completing tasks such as reading instructions, submit-ting an assignment, and posting to the discussion board,a chronological layout was more efficient. Figures 7 and 8are an example of individual participant’s gaze plot for eachgroup while completing the second task of reading the assign-ment instructions. The visualizations show that when giventhe instruction to complete a task by week or module, thechronological layout was more compelling at guiding partici-pant’s visual attention to the weekly modules on the naviga-tion menu. Not to mention, those in the Chronological groupcommitted fewer mistakes than participants in the Functionalgroup for all instructional activities, with the exception oflocating grades.What was les
to find instructions, and assignments and discussion boards - modules was the most effective.
Functional group completed the prescribed tasks fasterthan the participants in the Chronological group. In particu-lar, the completion time was faster in the Functional group forstudents to locate the syllabus, look up their grades, and findthe help link. With the precise name of the link to the coursesyllabus directly at the top of the main navigation area, it wasextremely easy for participants to find correctly without delay.Similarly, looking up grades and finding the help link wasstraight-forward in the functional layout.
with modules you still have this
Some participants alsocommented on the lack of organization with the menu items orhaving extra menu items that were not used in the course, whichled to confusion.
issues Lack of organization in menu items extra menu items
The overarching motivation behind this line of research isan interest in developing course sites that are potentially moreintuitive to navigate for students, which could potentiallyenhance student learning experiences through the reductionof extraneous cognitive load (Sweller, 2016).
Course design should reduce cognitive load
usability looks at how easy the interface is to use andconsists of five quality components: learnability, efficiency, mem-orability, errors, and satisfaction
usability - learnability efficiency memorability errors satisfaction
esearch has also shown that social presence can influ-ence students’ learning experiences, including students’ participation and motivationto participate
student motivation
Research has shown us that students’ relationshipswith faculty have a direct and significant effect on their scholarly engagement
instructor - student relationship
five integrated elements:affective association, community cohesion, instructor involvement,interaction intensity, and knowledge and experience. Examining theconcept of social presence through this lens allows us to understand howthese elements relate to satisfactory online experiences
5 integrated elements of Social presence affective association, community cohesion instructor involvement interaction intensity knowledge experience
who determine the five most important elements of social presenceto be social respect, social sharing, open mind, social identity, andintimacy. All these facets are areas in which video and voice can enrichonline students’ learning experience.
5 most important elements of social presence social respect social sharing open mind social identity imtimacy
enriched by video and voice.
video chats were one of the factorsstudents reported to increase the teacher-student relationship
video chats
Social presence is increased when the class moves away frombeing purely text based and incorporates voice and video
Voice and Video increases social presence
A study by Glazier (2016) of 465 studentsover six years compared one course that used built-in rapport-buildingstrategies, such as humanized instruction features like video, extensivepersonalized feedback on assignments, and personalized emails, to anonline course with none of the above rapport-building strategies. The studyexamined rapport through course grades and an anonymous studentsurvey. Both qualitative and quantitative data show that rapport buildingby the instructor can improve student success as measured by coursegrades and retention rates (Glazier, 2016)
rapport building by instructor improves student success
three distinct elements that contribute tostudent engagement: course design, instructor role, and student role
student engagement factors: Course design Instructor role Student Role
posit that without specialconsideration, the typical asynchronous discussion format of many onlinecourses aligns poorly with constructivist theory and the nature of learningcomplex course material, such as that which is found in most MAEdcourses.
design of online asynchronous discussions
were significantly more likely to saythat assignments were the most important factor, and they ranked course organization significantly higherthan students who chose face-to-face classes
assignments most important to online courses
. Studies indicate that the most common factors impacting online student retention arestudent motivation and faculty/student interaction or engagement
online retention factor
If an activity is both meaningful and engaging, you’re golden, and if it’s neither you’ve got a one-way ticket to dullsville.
for - boredom - factors - boredom - quote
quote - boredom - ( see below)
both factors—a dearth of meaning and a breakdown in attention—play independent and roughly equal roles in boring us.
for - boredom - factors
Thecalamity of the unexpected surrender, the “bleeding borders” re-drawn in the postwar settlement at Versailles, and the overwhelm-ing chaos of the inflation in the early 1920s were collective experi-ences that made the suffering of the nation more comprehensible.During the Weimar years, the people’s community denoted the be-leaguered condition Germans shared, while expressing the politicalunity necessary for national renewal.
heNazis responded to an intense desire for order in Germany in 1933.Fears of Communist revolutionaries mingled with more generalanxieties about crime and delinquency.
Socialists around the worldhad celebrated May Day as a festival of labor since the 1880s; butin Germany they had failed to get the official recognition the Nazisnow offered. So strong were the hopes for national unity that theGerman Free Trade Unions welcomed the Nazi gesture and encour-aged members to participate in the celebrations.
The state of permanent emer-gency declared by the National Socialists helps explain the tremen-dous efforts that they and their followers made to reconstruct thecollective body and the satisfaction they took in images of unityand solidarity. It also helps explain the violent exclusions they ac-cepted as part of the rebuilding process.
. It was the experience of conversion, which left peoplelike Dürkefälden and Ebermayer isolated, that was new and pro-vided the Third Reich with legitimacy and energy.
“he doesn’t want to take part in any waragain,” Karl reported; “he has had enough.”
the prospect of a new war, a topic Germanfamilies discussed frequently in the years after 1933
The strong presence of the police,who tended to sympathize with the National Socialists, restrictedthe mobility of opponents, while Nazi toughs broke into SocialDemocratic or trade union offices and Nazi officials banned so-cialist newspapers.
the “August Days” of 1914, when thou-sands of Germans rallied in the streets to support the national causein time of war, revealed extraordinary emotional investment in thepromise of national unity.
The enduring popularity of the Nazis rested on the idea of theVolksgemeinschaft, or people’s community.
volksgemeinschaft - people's community
Germans converted to National Socialism out of fear and for thesake of appearances. Indeed, each diary refers to concentrationcamps, arrests, and other violence. Moreover, pressure to conformto Nazi expectations persisted, a fact that Karl’s father tried topoint out. Like Friedrich Kassler, Germans also converted becausethey were persuaded finally that Nazism represented a “new direc-tion,” which offered opportunities and to which citizens simply hadto adapt. In addition, there were countless people who mistrustedthe Nazis, misunderstood their racial precepts, and resented theirhostility to the churches, but nonetheless endorsed the “nationalrevolution” of January 1933 and the political reconciliation it ap-peared to achieve. In some ways, Erich Ebermayer falls into thiscategory. Finally, Germans converted because they were genuinelyattracted to the social and political vision of National Socialism andparticularly to the promise of the people’s community.
reasons for german conformity - fear of nazi retaliation - maintaining appearances with other germans - pressure to conform - new opportunities in nazi society - disliked nazis but liked german unity - in search of national community - agreed w nazis socially and politically
for - Biden vote - Gen z factors - adjacency - 2024 U.S. elections - Trump vs Biden - Gen Z is an important demographic
adjacency - between - 2024 U.S. elections - Trump vs Biden - Gen Z is an important demographic - adjacency statement - Gen Z can play a critical role in the 2024 U.S. elections. - Pro - they care about environment - Con - not many of them may bother voting - Challenge - reaching them with the right message
but from previous experiences like this, the feature set has to be robust at the start or I think adoption will suffer.
four mitigating factors that make power appear to corrupt when something else is actually going on.
Refinements themselves present a significant hurdle to adoption by virtue of their limitations and overall introduction of conceptual complexity. So it’s a tough sell to recommend this for anything outside of personal projects or places with incredibly strong esoteric Ruby knowledge (like, say, hidden away within Rails).
Review coordinated by Life Science Editors
Reviewed by: Dr. Helen Pickersgill, Life Science Editors
Potential Conflicts of Interest: None
Impact Point: Transcription factors may mediate the release of specific genes in extracellular vesicles that could be taken up by other cells and directly influence their behaviour.
Background: Extracellular vesicles (EVs) are nanoscale, membrane-bound vesicles containing proteins, nucleic acids and lipids that are released by most cell types. Originally thought of as a cell waste disposal mechanism, they have since been rebranded as a means of intercellular communication, both short and long range, (like a cellular postal service), and can, for example, modify gene expression and function in recipient cells via the transfer of specific RNAs (DOI: 10.1038/s41580-020-0251-y). One interesting function for EVs was the recent discovery that antigen presenting cells (APCs) could donate telomeres via EVs to recipient T cells and rescue them from senescence (DOI: 10.1038/s41556-022-00991-z).
Given EVs contain a wide variety of cargos derived from the secreting cells, which have been extensively profiled (e.g., DOI: 10.1016/j.cell.2020.07.009) they are particularly interesting as sources of biomarkers for diagnosing diseases such as cancer (e.g., DOI: 10.1038/s12276-019-0219-1). We might also be able to use them as stable delivery mechanisms for controlling cell behaviour or targeting therapeutics/diagnostics.
We know quite a bit about how RNAs and proteins are selected for secretion by EVs (mediated by the autophagy protein LC3: e.g., DOIs: 10.1080/15548627.2020.1756557; 10.1038/s41556-019-0450-y). But little is known about DNA. DNA presents a particular challenge as it is packed up into the nucleus. This is also particularly important to understand in the context of horizontal gene transfer, i.e., passing functional genes between cells.
Main question: How does a cell ‘select’ specific DNA cargo from the nucleus and enable it to be released by EVs?
The advance: They discover that a transcription factor (FOXM1) plays a central role in mediating DNA release in EVs.
Results: • FOXM1 and LC3 (autophagy protein) colocalize and interact in cultured cells (coIP endogenous and exogenous, EMSA, immunostaining and identify an FOXM1-binding domain mutant). • FOXM1, LC3 and DNA colocalise in the cytoplasm in cultured cells, which increases upon starvation-induced autophagy (immunofluorescence). • FOXM1 and LC3 are found in EVs released from cultured cells (Western blot). • 15,544 DNA identified in EVs released from cultured cells (evDNA sequencing), of which 25 overlapped with DNA loci binding FOXM1 (ChIP). • FOXM1-bound nuclear DNA is transported to the cytoplasm upon induction of autophagy and is released in EVs in cultured cells (knock-in tagged chromatin with CRISPR-cas9, IF and PCR). This is dependent on FOXM1 (knock-out in cultured cells).
Significance: Transcription factors display strong DNA binding specificity and so are ideal candidates for directing specific genes into EVs for potential transfer to recipient cells.
Remaining questions/points: Care needs to be taken with regard to purification of EVs. Are the FOXM1-DNAs in the EVs functional in recipient cells? Is the DNA being actively ‘selected’ for an intercellular signalling purpose or is this just random degradation? Is it all FOXM1 bound DNA that has the potential to be trafficked to EVs or just a subset? Do other transcription factors have the same function or is it specific to this protein/family? Does this mechanism occur in other contexts (e.g., in vivo, under disease conditions).
ReconfigBehSci. (2021, February 1). @MaartenvSmeden @richarddmorey 2/2 Having conducted experiments on lay understanding of arguments from ignorance, in my experience, people intuitively understand probabilistic impact of factors, such as quality of search, that moderate strength. Rather than build on that, we work against it with slogan! [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1356228495714746370
ReconfigBehSci. (2020, October 31). RT @learnfromerror: PHIL STAT FORUM NOVEMBER 19; STEPHEN SENN ‘Randomisation and Control in the Age of Coronavirus?’ https://t.co/hqT8GWTqC… [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1323311706609721344
Multiple factors appear to increase the risk of PGD, including depression, anxiety disorders, current substance use/abuse, multiple losses, particularly stressful circumstances surrounding the death, lack of social supports, uncertainty about the death, and the unavailability of usual mourning rituals.
depression, anxiety disorders, current substance use/abuse, multiple losses, particularly stressful circumstances surrounding the death, lack of social supports, uncertainty about the death, the unavailability of usual mourning rituals
‘No one wanted to read’ his book on pandemic psychology – then Covid hit. (2021, August 19). The Guardian. http://www.theguardian.com/us-news/2021/aug/19/book-psychology-pandemics-steven-taylor
We should think about the number of simultaneous connections (peak and average) and the message rate/payload size. I think, the threshold to start thinking about AnyCable (instead of just Action Cable) is somewhere between 500 and 1000 connections on average or 5k-10k during peak hours.
number of simultaneous connections (peak and average)
the message rate/payload size.
Rather than write new tooling we decided to take advantage of tooling we had in place for our unit tests. Our unit tests already used FactoryBot, a test data generation library, for building up test datasets for a variety of test scenarios. Plus, we had already built up a nice suite of helpers that we coud re-use. By using tools and libraries already a part of the backend technology’s ecosystem we were able to spend less time building additional tooling. We had less code to maintain because of this and more time to work on solving our customer’s pain points.
The problem domain and the data involved in this project was complicated enough. We decided that not having to worry about unknowns with the frontend end-to-end testing stack helped mitigate risk. This isn’t to say you should always going with the tool you know, but in this instance we felt it was the right choice.
This particular project team came in with a lot of experience using testing tools like RSpec and Capybara. This included integrating with additional tools like Selenium WebDriver, Chrome and Chromedriver, data generation libraries like FactoryBot, and task runners like Rake. We had less experience doing end-to-end testing with Protractor even though it too uses Selenium WebDriver (a tool we’re very comfortable with).
There are times to stretch individually and as a team, but there are also times to take advantage of what you already know.
Osmanov, I. M., Spiridonova, E., Bobkova, P., Gamirova, A., Shikhaleva, A., Andreeva, M., Blyuss, O., El-Taravi, Y., DunnGalvin, A., Comberiati, P., Peroni, D. G., Apfelbacher, C., Genuneit, J., Mazankova, L., Miroshina, A., Chistyakova, E., Samitova, E., Borzakova, S., Bondarenko, E., … Sechenov StopCOVID Research Team. (2021). Risk factors for long covid in previously hospitalised children using the ISARIC Global follow-up protocol: A prospective cohort study [Preprint]. Pediatrics. https://doi.org/10.1101/2021.04.26.21256110
Young, K. S., Purves, K. L., Huebel, C., Davies, M., Thompson, K. N., Bristow, S., Krebs, G., Danese, A., Hirsch, C., Parsons, C. E., Vassos, E., Adey, B., Bright, S., Hegemann, L., Lee, Y. T., Kalsi, G., Monssen, D., Mundy, J., Peel, A., … Breen, G. (2021). Depression, anxiety and PTSD symptoms before and during the COVID-19 pandemic in the UK [Preprint]. PsyArXiv. https://doi.org/10.31234/osf.io/sf7b6
Blakemore, E. (n.d.). New diabetes cases linked to covid-19. Washington Post. Retrieved February 11, 2021, from https://www.washingtonpost.com/health/2021/02/01/covid-new-onset-diabetes/
Elgar, F. J., Stefaniak, A., & Wohl, M. J. A. (2020). The trouble with trust: Time-series analysis of social capital, income inequality, and COVID-19 deaths in 84 countries. Social Science & Medicine, 263, 113365. https://doi.org/10.1016/j.socscimed.2020.113365
Chambon, Monique, Jonas Dalege, Lourens Waldorp, Han van der Maas, Denny Borsboom, and Frenk van Harreveld. ‘A Complex Systems Perspective on Compliance with Behavioral Measures during the COVID-19 Pandemic in the Netherlands: How Psychological Networks Can Inform Interventions.’ PsyArXiv, 31 March 2021. https://doi.org/10.31234/osf.io/fmu9w.
Hein, G., Gamer, M., Gall, D., Gründahl, M., Domschke, K., Andreatta, M., Wieser, M. J., & Pauli, P. (2021). Social cognitive factors outweigh negative emotionality in predicting COVID-19 related safety behaviors. PsyArXiv. https://doi.org/10.31234/osf.io/5sbzy
Lopez-Persem, A., Bieth, T., Guiet, S., Ovando-Tellez, M., & Volle, E. (2021). Through thick and thin: Changes in creativity during the first lockdown of the Covid-19 pandemic. PsyArXiv. https://doi.org/10.31234/osf.io/26qde
Lee, Elizabeth C., Nikolas I. Wada, M. Kate Grabowski, Emily S. Gurley, and Justin Lessler. ‘The Engines of SARS-CoV-2 Spread’. Science 370, no. 6515 (23 October 2020): 406–7. https://doi.org/10.1126/science.abd8755.
Endress, Ansgar. ‘The Values of Survival: Socio-Cultural Values Predict COVID-19-Related Mortality’. PsyArXiv, 3 December 2020. https://doi.org/10.31234/osf.io/da95b.
Clift, Ash K., Carol A. C. Coupland, Ruth H. Keogh, Karla Diaz-Ordaz, Elizabeth Williamson, Ewen M. Harrison, Andrew Hayward, et al. ‘Living Risk Prediction Algorithm (QCOVID) for Risk of Hospital Admission and Mortality from Coronavirus 19 in Adults: National Derivation and Validation Cohort Study’. BMJ 371 (20 October 2020): m3731. https://doi.org/10.1136/bmj.m3731.
November 19: “Randomisation and control in the age of coronavirus?” (Stephen Senn). (2020, October 30). PhilStatWars. https://phil-stat-wars.com/2020/10/30/november-19-randomisation-and-control-in-the-age-of-coronavirus-stephen-senn/
Giesbrecht, G. (2020, October 2). Protocol for the Canadian Pregnancy During the COVID-19 Pandemic study. https://doi.org/10.31234/osf.io/w8hd5
Rogers, Andrew H., Lorra Garey, and Michael J. Zvolensky. “COVID-19 Psychological Factors Associated with Pain Status, Pain Intensity, and Pain-Related Interference.” Cognitive Behaviour Therapy, February 10, 2021, 1–13. https://doi.org/10.1080/16506073.2021.1874504.
Grundy. E., (2020) SCRUB PROJECT WAVE 4: AUSTRALIANS’ VIEWS ON PRIVATE GATHERINGS, REMOTE WORKING AND GETTING TESTED. Behaviour Works Australia. Retrieved from https://www.behaviourworksaustralia.org/scrub-project-wave-4-australians-views-on-private-gatherings-remote-working-and-getting-tested/
Papageorge. N. W., Zahn. M. V. Belot. M., van den Broek-Altenburg. E., Choi. S., Jamison. J. C., (2020). Socio-Demographic Factors Associated with Self-Protecting Behavior during the COVID-19 Pandemic. Institute of Labor Economics. Retrieved from: https://covid-19.iza.org/publications/dp13333/
going back to find something they found before
Muge Cevik [mugecevik] (2020/09/21) Over the last 6 months, we've learned a lot about how SARS-CoV-2 spreadsMicrobe What does the evidence so far tell us about SARS-CoV-2 transmission dynamics, high-risk activities and environments? Thread Thread (1/n) https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3692807 [tweet]. [twitter], https://twitter.com/mugecevik/status/1308080079763902464
It is very important that "production ready" UI libraries are available because otherwise the use of Svelte cannot be argued. A key point would be to make it easy possible that people can contribute
Developmental benzo[a]pyrene (B[a]P) exposure impacts larval behavior and impairs adult learning in zebrafish
A truly enjoyable read about specific environmental factors and their effect on learning in adult zebra fish. Although the study was done on fish, it is known that this particular contaminant effects humans as well in many ways, including in intelligence. The fact that this contaminant was found to effect learning and memory in adult fish reminds us to consider multiple aspects when constructing educational environments. Physical location and learning environment can greatly impact adult learning outcomes and is rarely talked about in adult learning theory papers. 10/10 for interest, 1/10 for relevance to this class.
Muge Cevik {@mugecevik} (2020) Over the last 6 months, we've learned a lot about how SARS-CoV-2 spreadsMicrobe What does the evidence so far tell us about SARS-CoV-2 transmission dynamics, high-risk activities and environments? Thread. Twitter. Retrieved from: https://twitter.com/mugecevik/status/1308080065830363138
Racine, S. E., Miller, A. E., Mehak, A., & Trolio, V. (2020, September 14). Examining Risk and Protective Factors for Psychological Health during the COVID-19 Pandemic. https://doi.org/10.31234/osf.io/ys8fn
Lee, Hyeon-seung, Derek Dean, Tatiana Baxter, Taylor Griffith, and Sohee Park. ‘Deterioration of Mental Health despite Successful Control of the COVID-19 Pandemic in South Korea’. Preprint. PsyArXiv, 30 August 2020. https://doi.org/10.31234/osf.io/s7qj8.
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Meeting the psychological needs of people recovering from severe coronavirus. (2020, May 7). https://www.youtube.com/watch?v=6hAUUTdhHlc&feature=youtu.be
r/BehSciAsk - Scibeh’s first Policy Problem Challenge: Relaxing the 2 m social distancing rule. (n.d.). Reddit. Retrieved June 12, 2020, from https://www.reddit.com/r/BehSciAsk/comments/h0zaco/scibehs_first_policy_problem_challenge_relaxing/
Disappointingly, a recent meta-analysis failed to demonstrate any value for autologous platelet-rich plasma in the treatment of chronic wounds
This approach allows treatment with patient-specific factors at an apparently physiologic ratio of growth factor concentrations.
Autologous growth factors are harvested from the patient’s own platelets, yielding an unpredictable combination and concentration of factors, which are then applied to the wound.
Fibroblasts stimulated by growth factors can produce type I collagen and glycosaminoglycans (e.g., chondroitin sulfates), which adhere to the wound surface to permit epithelial cell migration, as well as adhesive ligands (e.g., the matrix protein fibronectin), which promote cell adhesion.
The first is the way the natural scientific community operates.
First Factor encouraging professional environmentalists in their denial of social collapse in the near term
Especially in situations of shared powerlessness, it can be perceived as safer to hide one's views and do nothing if it goes against the status quo.
convergence of several societal factors
Discuss what these societal factors may have included.
Instructional Design Strategies for Intensive Online Courses: An Objectivist-Constructivist Blended Approach
This was an excellent article Chen (2007) in defining and laying out how a blended learning approach of objectivist and constructivist instructional strategies work well in online instruction and the use of an actual online course as a study example.
RATING: 4/5 (rating based upon a score system 1 to 5, 1= lowest 5=highest in terms of content, veracity, easiness of use etc.)
Distance Education Trends: Integrating new technologies to foster student interaction and collaboration
This article explores the interaction of student based learner-centered used of technology tools such as wikis, blogs and podcasts as new and emerging technology tools. With distance learning programs becoming more and more popular, software applications such as Writeboard, InstaCol and Imeem may become less of the software of choice. The article looks closely at the influence of technology and outcomes.
RATING: 4/5 (rating based upon a score system 1 to 5, 1= lowest 5=highest in terms of content, veracity, easiness of use etc.)
Factors Influencing Teachers' Integration of ICT in Teaching and Learning
ICT is enhancing communication in the digital learning environment. In this article the integration of ICT is explored and reveals how both teachers and students are able to better utilize their digital options 24/7 more effectively and efficiently. In addition, a gap has been identified in being showing how to best use ICT in the learning environment and included are in-depth studies of its’ use. The article identifies factors influencing teachers’ decision to integrate ICT in teaching.
RATING: 4/5 (rating based upon a score system 1 to 5, 1= lowest 5=highest in terms of content, veracity, easiness of use etc.)
A visual exploration of the link between statin use and the risk of Diabetes in a subpopulation of patients with subclinical hypothyroidism.
This is an interactive graph created with Biovista Vizit; nodes and links can be further explored to view supporting bibliography and molecular mechanism of action.
knowledge of student thinking and learning, knowledge of subject matter, and increasingly, knowledge of technology.
3 important factors