46 Matching Annotations
  1. Dec 2022
    1. forced on the population

      at least in the US, no one is being forced to get a vaccine. Not only that, but there's no evidence anyone's even considered it: https://www.snopes.com/fact-check/forced-vaccines-covid-19/

      Maybe they're talking about another population?

    1. We analyzed URLs cited in Twitter messages before and after the temporary interruption of the vaccine development on September 9, 2020 to investigate the presence of low credibility and malicious information. We show that the halt of the AstraZeneca clinical trials prompted tweets that cast doubt, fear and vaccine opposition. We discovered a strong presence of URLs from low credibility or malicious websites, as classified by independent fact-checking organizations or identified by web hosting infrastructure features. Moreover, we identified what appears to be coordinated operations to artificially promote some of these URLs hosted on malicious websites.
    1. We found that misinformation-exposure scores are significantly positively related to language toxicity (Fig. 3a; b = 0.129, 95% CI = [0.098, 0.159], SE = 0.015, t (4121) = 8.323, p < 0.001; b = 0.319, 95% CI = [0.274, 0.365], SE = 0.023, t (4106) = 13.747, p < 0.001 when controlling for estimated ideology) and expressions of moral outrage (Fig. 3b; b = 0.107, 95% CI = [0.076, 0.137], SE = 0.015, t (4143) = 14.243, p < 0.001; b = 0.329, 95% CI = [0.283,0.374], SE = 0.023, t (4128) = 14.243, p < 0.001 when controlling for estimated ideology). See Supplementary Tables 1, 2 for full regression tables and Supplementary Tables 3–6 for the robustness of our results.
    1. Exposure to elite misinformation is associated with sharing news from lower-quality outlets and with conservative estimated ideology.

      Shown is the relationship between users’ misinformation-exposure scores and (a) the quality of the news outlets they shared content from, as rated by professional fact-checkers21, (b) the quality of the news outlets they shared content from, as rated by layperson crowds21, and (c) estimated political ideology, based on the ideology of the accounts they follow10. Small dots in the background show individual observations; large dots show the average value across bins of size 0.1, with size of dots proportional to the number of observations in each bin.

    1. We find that, during the pandemic, no-vax communities became more central in the country-specificdebates and their cross-border connections strengthened, revealing a global Twitter anti-vaccinationnetwork. U.S. users are central in this network, while Russian users also become net exporters ofmisinformation during vaccination roll-out. Interestingly, we find that Twitter’s content moderationefforts, and in particular the suspension of users following the January 6th U.S. Capitol attack, had aworldwide impact in reducing misinformation spread about vaccines. These findings may help publichealth institutions and social media platforms to mitigate the spread of health-related, low-credibleinformation by revealing vulnerable online communities
    1. Engagement of religious leaders, for example, has been documented as an important approach to improve vaccine acceptance16,57. Key to the preparation of a COVID-19 vaccine is, therefore, the early and frequent engagement of religious and community-leaders58, and for health authorities to work collaboratively with multiple societal stakeholders to avoid the feeling that they are only acting on behalf of government authorities59.
    2. Similar rates of vaccine hesitance (26% and 25%) and resistance (9% and 6%) were evident in the Irish and UK samples, with only 65% of the Irish population and 69% of the UK population fully willing to accept a COVID-19 vaccine. These findings align with other estimates across seven European nations where 26% of adults indicated hesitance or resistance to a COVID-19 vaccine7 and in the United States where 33% of the population indicated hesitance or resistance34. Rates of resistance to a COVID-19 vaccine also parallel those found for other types of vaccines. For example, in the United States 9% regarded the MMR vaccine as unsafe in a survey of over 1000 adults35, while 7% of respondents across the world said they “strongly disagree” or “somewhat disagree” with the statement ‘Vaccines are safe’36. Thus, upwards of approximately 10% of study populations appear to be opposed to vaccinations in whatever form they take. Importantly, however, the findings from the current study and those from around Europe and the United States may not be consistent with or reflective of vaccine acceptance, hesitancy, or resistance in non-Western countries or regions.
  2. Apr 2022
  3. Mar 2022
  4. Feb 2022
  5. Jan 2022
  6. Dec 2021
  7. Nov 2021
    1. It remains unclear whether the reduction in the neutralization sensitivity of the N501Y.V2 strain to vaccine-induced antibodies is enough to seriously reduce vaccine efficacy. First, mRNA vaccines also induce virus-specific helper T cells and cytotoxic T cells, both of which might be involved in protection against challenge. Also, the mRNA vaccines, in particular, induce such a strong NAb response that there could be enough “spare capacity” to deal with reductions in the sensitivity of the variant to NAbs. In other words, N501Y.V2 (and the related virus from Brazil) may be less sensitive to NAbs, but not to an extent that will cause widespread vaccine failure.

      Variants that show reduced sensitivity to NAbs don't necessarily mean mRNA vaccine failure

      New variants may emerge that show reduced sensitivity to NAbs.

      This may not result in vaccine failure because:

      1. The mRNA vaccines induce such a strong NAb response, there will be enough spare capacity to deal with the virus.
      2. The mRNA vaccines also induce other virus specific protection such as helper T cells and cytotoxic T cells, which may not be affected by the reduction in NAb sensitivity.
    1. Vaccine effectiveness against laboratory-confirmed symptomatic infection is never higher than 50 to 60%, and in some years it is much lower.

      Vaccine effectiveness for influenza vaccines for symptomatic infection is never higher than 50-60% and some years it is much slower.

    2. The effect on asymptomatic infections was a welcome surprise, because it has been thought that most vaccines for respiratory illnesses, including influenza, are “leaky” — that is, they allow some degree of asymptomatic infection and are better at preventing symptomatic infection.

      Most vaccines for respiratory illnesses are leaky.

      The efficacy the mRNA vaccines showed in preventing asymptomatic transmission was therefore a welcome surprise.

  8. Oct 2021
  9. Jul 2021
  10. Jun 2021
  11. May 2021
  12. Mar 2021
  13. Feb 2021
  14. Dec 2020
  15. Sep 2020
  16. Aug 2020