33 Matching Annotations
  1. Jan 2024
  2. Nov 2023
    1. 2. La vioLation du principe deneutraLité poLitique peut-eLLejustifier Le refus de diffusiond’un document ?Non. Le CDPE des Vosges a obtenu du Tribunal ad-ministratif de Nancy l’annulation du refus de distri-bution d’un tract qu’il avait rédigé et appelant à unesemaine de mobilisation nationale pour s’opposer auxsuppressions de postes dans l’enseignement. Dansson jugement du 2 octobre 2012, le tribunal relèveque l’administration a fondé son refus sur une pré-tendue violation du principe de laïcité (critère prévupar la loi mais nullement violé en l’espèce) et sur uneprétendue violation du principe de « neutralité poli-tique » qui n’est pas prévu par l’article D.111-9 ducode de l’éducation et qui, comme le rappelle le tri-bunal, « s’impose aux seuls agents du service ». La« neutralité politique » ne peut donc pas justifier unrefus de distribution par l’établissement.
  3. Oct 2023
    1. Despite disagreement about the role of fly-ways in limiting viral spread among wild birds (17,18), therapid spatial diffusion and transmission of HPAIV in wildand domestic birds highlight the need to further investigatethe processes involved in viral emergence and spread.
  4. Jun 2023
  5. May 2023
    1. iron-bearing transferrin interacts with its receptor
      1. Iron is transported in the blood by the iron-transferrin complex.
      2. The complex interacts with specific transferrin receptors on the surface of cells that express transferrin receptors, such as developing erythroblast cells.
      3. The iron-bearing transferrin is internalized via clathrin-coated pits and transported to an acidic endosome.
      4. Iron is released from the transferrin at the low pH of the endosome.
      5. Iron is made available for heme synthesis.
      6. The transferrin-receptor complex is recycled to the surface of the cell.
      7. The bulk of the transferrin is released back into circulation, and the transferrin receptor re-anchors into the cell membrane.
      8. Iron in excess of the amount needed for hemoglobin synthesis binds to a storage protein, apoferritin, forming ferritin.
      9. Senescent red cells are recognized by the cells of the reticuloendothelial system and undergo phagocytosis.
      10. Hemoglobin is broken down, and the iron is shuttled back to the surface of the RE cell.
      11. Iron is presented to circulating transferrin via the iron export channel, ferroportin.
      12. Iron is then available for reutilization for hemoglobin synthesis
  6. Dec 2022
    1. I just can’t stop dreaming about a perfect world where I could go back to any of my old JavaScript projects with an ease of mind and knowing that everything just works. A perfect world where my program is going to stand the test of time.

      That's a you-problem. The pieces are there—the language is stable, and there's a ludicrously backwards compatible World Wide Wruntime that you can trust to be around—it's on you if it fails.

    1. In this work, we develop the “Multi-Agent, Multi-Attitude” (MAMA) model which incorporates several key factors of attitude diffusion: (1) multiple, interacting attitudes; (2) social influence between individuals; and (3) media influence. All three components have strong support from the social science community.

      several key factors of attitude diffusion: 1. multiple, interacting attitudes 2. social influence between individuals 3. media influence

  7. Nov 2022
    1. The erupting volcano represents Productive ambiguity. This is where the real work is done at scale. Concepts can be productively ambiguous through straight metaphor, or by mass (media) convergence on a particular term. It resonates with many people.

      New, relatively well-formed ideas may have lost much of their ambiguity to their creators, but they're solid enough to be communicated at scale to others. The newness of the concepts as they're accepted and used by others provides a tremendous level of productive ambiguity as the ideas spread and further solidify and are combined with a broader field of pre-existing ideas.

  8. Sep 2022
  9. Jul 2022
    1. probefahrer · 7 hr. agoAre you familiar with Mark Granovetter‘s theory of weak ties?He used it in the sense of the value of weak social connections but I am pretty sure one could make a case for weak connections in a Zettelkasten as being very valuable

      Humanity is a zettelkasten in biological form.

      Our social ties (links) putting us into proximity with other humans over time creates a new links between us and our ideas, and slowly evolves new ideas over time. Those new ideas that win this evolutionary process are called innovation.

      The general statistical thermodynamics of this idea innovation process can be "heated up" by improving communication channels with those far away from us (think letters, telegraph, radio, television, internet, social media).

      This reaction can be further accelerated by actively permuting the ideas with respect to each other as suggested by Raymond Llull's combinatorial arts.

      motivating reference: Matt Ridley in The Rational Optimist

      link to: - Mark Granovetter and weak ties - life of x

  10. Jun 2022
    1. the time you sit down tomake progress on something, all the work to gather and organize thesource material needs to already be done. We can’t expectourselves to instantly come up with brilliant ideas on demand. Ilearned that innovation and problem-solving depend on a routine thatsystematically brings interesting ideas to the surface of ourawareness.

      By writing down and collecting ideas slowly over time, working on them in small fits and spurts, when one finally comes to do the final work on their writing project or other work, the pieces only need minor shaping to take their final form. This process allows for a much greater level of serendipity, creativity, and potential sustained genius of connecting ideas across time to take shape in a final piece.


      How does this relate to diffuse thinking? How can slow diffuse thinking be leveraged into this process?

      Writing down fleeting notes while walking around can be valuable as one's ideas brew slowly in the mind (diffuse thinking) in combination with active combinatorial creativity, thus a form of Llullan combinatorial diffusion.


      Many business books seem so shallow and often only have one real insight which is repeated multiple times, perhaps to drive the point home or perhaps just to have enough filler to seem being worth the purchase of a book.

      Napoleon Hill's Think and Grow Rich is an example of this, though it shows a different form of genius in expanding the idea from a variety of perspectives so that eventually everyone will absorb the broader idea which is distilled to great effect into the title.

  11. May 2022
    1. new result, test it against each of your twelve problems to seewhether it helps. Every once in a while there will be a hit, andpeople will say, “How did he do it? He must be a genius!”

      You have to keep a dozen of your favorite problems constantly present in your mind, although by and large they will lay in a dormant state. Every time you hear or read a new trick or a

      Gian-Carlo Rota, Indiscrete Thoughts (Boston: Birkhäuser Boston, 1997), 202.

      Richard Feynman indicated in an interview that he kept a dozen of his favorite problems at the top of his mind. As he encountered new results and tricks, he tried applying them to those problems in hopes of either solving them or in coming up with new ideas. Over time by random but combinatorial chance, solutions or ideas would present themselves as ideas were juxtaposed.

      One would suspect that Feynman hadn't actually read Raymond Llull, but this technique sounds very similar to the Llullan combinatorial arts from centuries earlier, albeit in a much more simplified form.

      Can we find evidence of Feynman having read or interacted with Llull? Was it independently created or was he influenced?

      I had an example of this on 2022-05-28 in Dan Allosso's book club on Equality in the closing minutes where a bit of inspiration hit me to combine the ideas of memes, evolution, and Indigenous knowledge and storytelling to our current political situation. Several of them are problems and ideas I've been working with over years or months, and they came together all at once to present a surprising and useful new combination. #examples

      Link this also to the idea of diffuse thinking as a means of solving problems. One can combine the idea of diffuse thinking with combinatorial creativity to super-charge one's problem solving and idea generation capacity this way. What would one call this combination? It definitely needs a name. Llullan combinatorial diffusion, perhaps? To some extent Llull was doing this already as part of his practice, it's just that he didn't know or write explicitly about the diffuse thinking portion (to my knowledge), though this doesn't mean that he wasn't the beneficiary of it in actual practice, particularly when it's known that many of his time practiced lectio divina and meditated on their ideas. Alternately meditating on ideas and then "walking away" from them will by force cause diffuse thinking to be triggered.

      Are there people for whom diffuse thinking doesn't work from a physiological perspective? What type of neurodiversity does this cause?

  12. Aug 2021
    1. The life cycle of technologies can be divided into stages – from invention, through research, development and dissemination (RD&D) and market development, to commercial diffusion.

      Memang aneh ketika siklus hidup teknologi didefinisikan secara seragam seperti ini, khususnya di bagian akhirnya, commercial diffusion.

  13. Feb 2021
  14. Oct 2020
  15. Sep 2020
  16. Aug 2020
  17. May 2020
  18. Apr 2020
  19. Mar 2020
  20. Dec 2019
    1. broaden the definition of a ‘researcher’ to include a molecular biologist and basic science researcher, and to widen the scope of research ethics

      In order to adapt to new contexts, policy diffusion often triggers such semantic drift of key concepts.

      Would be great to see that linked to the policy learning framework.

    2. CIOMS Guidelines serve as a helpful reference in the drafting of a new regulation

      Good example of policy diffusion

    3. based on the recommendations and standards set out by international organisations like the World Medical Association and CIOMS

      Reference to policy diffusion

    4. Regarding recommended practices in international ethical policy documents, these are not sufficiently disseminated or internalized, hence gaps still exist in relation to best practices and critical aspects of data practices. To address this challenge, it is not only essential to disseminate and promote these policies, but to also adapt them to the contexts and situations where they are applicable through training and capacity building.

      Given that the article is framed as being about policy diffusion and using a policy learning framework, I would have expected more details here.

  21. Jul 2019
    1. The web, in yet another example of its leveling effect, allows nearly everyone to see nearly every interface. Thus designers can learn rapidly from what others have done, and users can see if one web site's experience is substandard compared to others.
  22. Jun 2017
    1. Roewan Crowe, Associate Professor, Women’s and Gender Studies & Co-Director, Institute for Women’s & Gender Studies, University of Winnipeg. 2. Catherine Taylor, Professor, Faculty of Education and Dept of Rhetoric & Communications, University of Winnipeg. 3. Robin Jarvis Brownlie, Associate Professor, Department of History, University of Manitoba 4. Angela Failler, Chancellor’s Research Chair, Associate Professor, Women’s and Gender Studies, Research Affiliate Institute for Women’s and Gender Studies, University of Winnipeg. 5. Adele Perry, Associate Professor and Canada Research Chair, Department of History, University of Manitoba.

      Interesting to track this to the diffusion of ideas. Started in Manitoba.

  23. Feb 2014
    1. By contrast, any positive or negative effects that intellectual property rights have on the wider populace are diffused, and any individual member of the wider populace has little motive (and potentially insufficient means) to overco me the significant barriers to active political lobbying. As a result, the intrinsic trend is for intellectual INTELLECTUAL PROPERTY: POLICY FOR INNOVATION 11   property holders to actively lobby, largely unopposed, for greater rights protections. (Fisher, 1999, Sect. II. C.)

      Both positive and negative effects stemming from intellectual property rights to the wider populace are diffused, thus the wider populace has little motive to oppose changes to laws and policies that support intellectual property.