- Oct 2023
-
www.facultyfocus.com www.facultyfocus.com
-
Appreciative
Appreciation
-
-
www.nytimes.com www.nytimes.com
-
Neue, gigantische Fracking-Projekte in den USA („monster fracks“) verbrauchen enorme Mengen Wasser, so dass die Öl- und Gasfirmen inzwischen auch nach Wasser bohren. Damit wird die durch Übernutzung und globale Erhitzung prekäre Wasserversorgung in vielen Gegenden der USA zusätzlich belastet. Analyse und Reportage in der New York Times, die herazusgefunden hat, dass die monster fracks in Texas inzwischen zwei Drittel der Fracking-Projekte ausmachen. https://www.nytimes.com/interactive/2023/09/25/climate/fracking-oil-gas-wells-water.html
-
- Aug 2023
-
baijiahao.baidu.com baijiahao.baidu.com
-
那么，如何让发起请求的时候，使用我们小号的私钥呢？我们先来看一下执行 clone 代码时候，仓库源那个以 git 开头的链接是什么意思：
给目标服务器配置别名
-
-
moochinaboutltd.bandcamp.com moochinaboutltd.bandcamp.com
- May 2023
-
vschsd.org vschsd.org
-
Muthu scowled. “I have to write I won’t be rude to myteachers one hundred times.”
on the matilda movie she has to do that
-
“That’s because Rukku is gone, Arul! She’s gone because of me.If I hadn’t forced her to leave home—”
i once saw a serie (flash) where the protagonist blamed herself for everything
-
He asked how I was doing, and when, as usual, I just said,“Fine,” he wouldn’t let me get away with it.“No,” he said. “You’re not fine, Viji.”I said nothing.
mom asks me how school was and this is always how it plays out
-
“I don’t mind if you have no faith in religion, Viji. Just as longas you have faith in the goodness within yourself.
my mother told me this berfore aswell
-
I’m not mean about any one religion,” I said. “They’re allequally silly.
i agree
-
Soon, I’d setthe whole place yawning.
this same thing happens when augusto shouts "BREEEK"
-
Celina Aunty called me into the schoolroom andmotioned me toward one of the empty desks.“Sit,” she ordered. “Write.”“Write?” I said. “Why?”
right when i was going to sleep my mother made me write and practice to pass a test
-
I tried a few times but kept choking up, unable to get beyondthe first sentences.
when i get exited or sad the same happens to me
-
hen I saw him—scrubbed clean by a nurse, with his hair cutshort and washed and brushed—I could hardly believe it wasMuthu.
when i take a bath i look 10x prettier aswell
-
“Life isn’t fair.
famous quote
-
Muthu lay in beds near one another. You were each hooked upto a contraption that dripped medicine and food and water into yourveins,
my cousin has once been in this situation
-
“Did you use mosquitonets?” “Did you boil the water before you drank it?” “Whatmedication did you try to give her?”
doctors ask the exact same questions to my mother when i go to a hospital
-
“Rich boys, for sure,” Arul said. “You have to be rich to wastetime going on escapades at night instead of catching up on precioussleep
i do homework in the middle of the night
-
Arul placed his candle beside the others. You watched asintently as when you made your bead necklaces.
ive done this before
-
As we walked away, you and Muthu started playing a game,tossing a bit of concrete into the air like a ball and trying to catch itagain before it fell.
i do this with a tenis ball and i catch it with a punch to practice
-
The drone of bloodthirsty mosquitoes had wokenme several times during the night, and my arms itched with bites.
This was a huge problem for me when i didnt have a ventilator, i would have to sleep in the couch but sometimes they followed
-
My voice came out all panicky. I had avision of a ghost swallowing you whole.
i had a dream i was escaping a ghost
-
But I cared. I cared about him as strongly as if we’d known eachother all our lives. I couldn’t imagine our future without him andMuthu in it.
i also met a girl in 5th grade which i loved, and i cared about her like i met her my whole life, but she left...
-
But my dad was the best fisherman in our village.
my father is also a good fisherman
-
I felt too excited to sleep, so I sneaked out to join him.
this happened once in a sleepover
-
“Don’t you ever think about the future?” I challenged him.“No,” Muthu said. “There’s enough to worry about every daywithout worrying about tomorrow.”
seems like the procrastinator version of me
-
You set it free, Rukku,” I cut him short. “Now it can goanywhere it feels like. That was really nice of you.”
i once did that because i thought it would go to space and find aliens
-
“Life isn’t a competition.”
this was said by Matthew west
-
Sullen faced, the boy named Sridar stepped away as Arul joinedus.“How are you, Kumar?” Arul said to the fuzzy-lipped boy.“Look, this is our place,” Kumar replied. “It’s okay for you tocome here, but you can’t bring along every new kid in the city.”“Enough here for us all to share,” Arul said.
this is just like an event of a movie i watched
-
I slowly rolled the spicy yellow mixture of rice and vegetablesand meat into little balls with my fingers and licked the sauce offmy hands.
this is exactly what skellig used to do
-
“You really never pray?” Arul looked horrified. “Even the wrongGods are better than no God.”
heard that before
-
It sounded like our father, O. R. T. Narayan,something something—all in English, not Tamil like Amma’sprayers.
i recognize this prayer and i used to preach it in the USA
-
Still, I felt thankful. Thankful we had at least that much. Mostof all, thankful that you were following me without a fuss, withKutti at your heels.
on skellig whisper was at her heels
-
“Give me something,” she whined. “I have to look after mybrother. See him?” She gestured at a small boy—stark naked—whowas sleeping behind her.
this situation happened to my family when we went to egypt
-
She sat with you, showing you ways to tie pretty knots and braidstrands together.
i tried to learn that when i was in a school on the USA
-
I looked behind us to see whom he was shooing.“You!” he yelled. “Get that dog away from my shop!”“It’s a good dog . . .” I began, but the man shook his fist at us.Kutti growled. I picked him up and held his squirming bodytight.
there is a movie where dogs are prohibited in a hotel but someone manages to sneak one in
-
“No banana?”“No, sorry.”“Papaya?” you suggested.“No.”“Guava?”“No. No pomegranate, no jackfruit, no oranges, no sapotes, nosweet limes. No nothing.”
seems like my fridge
-
“Want to come for a swim?” Muthu grinned at you. “The water’snice and cool.”
i like swimming
-
I couldn’t help petting him. His coat was smooth. He wiggledand sniffed my hand.
same, cant help petting my dog no matter what
-
“Get away from that puppy, Rukku. It might bite.”
My dog loves to bite
-
Homesicknesspinched my heart for a moment. I thought of the rare weekendswhen Appa was away and Amma had enough energy to join us so wecould cook a meal together.
how i felt when going to the nr
-
The smell of roasting chillis tickled my nose
the smell of crabs makes me feel that way
-
The conductor looked at me and then at you, and stuck a handin his pocket and pulled out a hard green sweet that had melted outof shape.
i have been to ubers that have this function
-
But I should have known she’d never tell.
On Breaking Bad the mother would never tell, despite desperately wanting to tell her husband's secret
-
he set packages wrapped in newspaper onthe cracked kitchen counter. “Presents for my girls.”
My father also gave me a wrapped present once
-
She didn’t finish her sentence. She didn’t need to. She’d told mea million times how scared she was that if you set foot in a hospital,the doctors might lock you away in “a mental institution.”
On a book i read a person died because they were too scared to go to the doctor for the same reason.
-
We’d just finished our dinner when we heard Appa’s heavyfootsteps. The sound of him staggering up the stairs to ourapartment told us all we needed to know.
This situation is similar, when my father arrives his footsteps are heavy so i know he arrived.
-
- Apr 2023
-
vschsd.org vschsd.org
-
payasam
I have eaten something like this.
-
-
-
For many people, “Camelot” is more familiar as a metaphor than as a musical — it depicts a noble effort to create a just society, often associated with the Kennedy administration, because Jacqueline Kennedy, in an interview shortly after President John F. Kennedy’s assassination, mentioned her husband’s fondness for the show, and quoted a final lyric: “Don’t let it be forgot, that once there was a spot, for one brief shining moment, that was known as Camelot.”
The Kennedy administration became culturally associated with Camelot because Jacqueline Kennedy mentioned her husband's affinity for the show in an interview with Theodore H. White for LIFE Magazine following his death and quoted the show's closing lyric: “Don’t let it be forgot, that once there was a spot, for one brief shining moment, that was known as Camelot.”
Somewhat curious that there's T. H. White of The Once and Future King and a separate Theodore H. White who interviewed Jackie Kennedy following her husband's death with mentions of Camelot.
-
- Mar 2023
-
www.statology.org www.statology.org
-
Some people argue that the Welch’s t-test should be the default choice for comparing the means of two independent groups since it performs better than the Student’s t-test when sample sizes and variances are unequal between groups, and it gives identical results when sample sizes are variances are equal. In practice, when you are comparing the means of two groups it’s unlikely that the standard deviations for each group will be identical. This makes it a good idea to just always use Welch’s t-test, so that you don’t have to make any assumptions about equal variances.
Tags
Annotators
URL
-
-
krebsonsecurity.com krebsonsecurity.com
-
A new breach involving data from nine million AT&T customers is a fresh reminder that your mobile provider likely collects and shares a great deal of information about where you go and what you do with your mobile device — unless and until you affirmatively opt out of this data collection. Here’s a primer on why you might want to do that, and how.
-
- Jan 2023
-
www.investopedia.com www.investopedia.comT-Test1
-
T-Test: What It Is With Multiple Formulas and When To Use Them
https://www.investopedia.com/terms/t/t-test.asp A t-test is an inferential statistic used to determine if there is a significant difference between the means of two groups and how they are related. T-tests are used when the data sets follow a normal distribution and have unknown variances, like the data set recorded from flipping a coin 100 times.
Tags
Annotators
URL
-
-
www.scribbr.com www.scribbr.com
-
An Introduction to t Tests | Definitions, Formula and Examples
How to TTEST
-
- Dec 2022
-
www.usgo.org www.usgo.org
-
- Nov 2022
-
archive.org archive.org
-
Pg. 52, 53, & 54
- Dietrich Bonheoffer, the 1st German lutheran Pator and theologians opposed Adolf Hitler's anti-semitic legislation called the Aryan Clause on April 7, 1933
- Reich church damded loyalty oath from all German Protestants who held church offices
- Bonheoffer refused and took lead in the alternative, confessing church movement
- he helped many jews escape the Germans as well as training other church leaders to do the same
- In June 1939 Bonhoeffer went to the U.S for the sake of his safety
- Bonheoffer specializes in theology
- He felt a calling to be involved in church and national affairs
- Bonheoffer worried that he is leaving god behind because he is not following his calling by staying to the U.S
- He was not allowed to return to Germany and this worried him
- June 20th, he feels uneasy and wishes to return home because God is giving him a sign "The reasons one gives for an action to others and to one's self are certainly inadequate... In the last resort one acts from a level which remains hidden from us. So we can only ask God to judge and forgive us.. it is now in his hands" (Cahalan, 54)
- July 9, 1939 he returns to Germany and resumes his efforts to resit hitlier and the Reich
- He wanted to assassinate Hitler (pg. 54)
- April 5, 1943 he was arrested for his activity in the underground resistance movement
Tags
Annotators
URL
-
-
www.allocine.fr www.allocine.frMR 731
- Oct 2022
-
latin.stackexchange.com latin.stackexchange.com
-
[T.S.] Eliot stood—as he once famously said of himself—for conservatism in politics, classicism in literature, and Catholicism, or rather Anglo-Catholicism, in religion. He looked back into the past, the mediaeval past, as a confirmed laudator temporis acti and in the mediaeval past he looked back not only to John Donne among the metaphysical poets, nor only to William Shakespeare among the Elizabethan dramatists, but before them to the great Dante among Italian poets and behind Dante, though not so obviously, to St. Thomas Aquinas among the scholastic theologians. (From "T.S. Eliot's Metaphysics" by Peter Milward, Culture and Civilization 2009.)
-
-
openintro-ims.netlify.app openintro-ims.netlify.app
-
However, its tails are thicker than the normal distribution’s, meaning observations are more likely to fall beyond two standard deviations from the mean than under the normal distribution.
This is what Dr. Herring meant by "fatter tails."
Below is why.
-
- Aug 2022
-
www.news-medical.net www.news-medical.net
-
Thomas, L. (2021, October 14). SARS-CoV-2 induces tissue immune memory. News-Medical.Net. https://www.news-medical.net/news/20211014/SARS-CoV-2-induces-tissue-immune-memory.aspx
-
-
www.theguardian.com www.theguardian.com
-
Beaumont, P. (2021, December 17). T-cells in Pfizer Covid jab recipients stay robust against severe illness. The Guardian. https://www.theguardian.com/world/2021/dec/17/t-cells-pfizer-covid-jab-robust-against-severe-illness-south-africa-research
-
-
findmymobile.samsung.com findmymobile.samsung.com
- Jun 2022
-
www.themarginalian.org www.themarginalian.org
-
T. S. Eliot believed that the poet’s mind incubates fragmentary thoughts into beautiful ideas
-
-
www.theatlantic.com www.theatlantic.com
-
In the 1920s and ’30s, the NRA was at the forefront of legislative efforts to enact gun control. The organization’s president at the time was Karl T. Frederick, a Princeton- and Harvard-educated lawyer known as “the best shot in America”—a title he earned by winning three gold medals in pistol-shooting at the 1920 Summer Olympic Games. As a special consultant to the National Conference of Commissioners on Uniform State Laws, Frederick helped draft the Uniform Firearms Act, a model of state-level gun-control legislation.
-
- May 2022
-
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
-
DICER1 syndrome encompasses a variety of benign and malignant manifestations including multinodular goitre
Gene: DICER1 PMCID: PMC8451242 PMID: 34552563 Pathogenic Inheritance Pattern: Autosomal Dominant MultipleDiseaseEntities Disease Entity: DICER1 syndrome, multinodular goitre, cystic nephroma, anaplastic renal sarcoma, Wilms tumour, differentiated thyroid carcinoma, gynandroblastoma, ciliary body medulloepithelioma, embryonal rhabdomyosarcoma, pineoblastoma, pituitary blastoma, kidney cyst, pulmonary cyst, Sertoli-Leydig Cell Tumor. Mutation: Germline MultipleGeneVariants Variant & Clinvar IDs: c.3452_3453del (485534), c.316del (no ClinVar ID), c.171_172insAC (no ClinVar ID), c.3434del (no ClinVar ID), c.988C>T (933007), c.5388dup (no ClinVar ID) Zygosity: None provided. Case: At time of operation, the goitre patients living in Denmark were ages 21, 12, 21, 8, 14, and 16. Four underwent total thyroidectomies, and two underwent partial thyroidectomies. The patient originally aged 21 previously had a kidney cyst at age 14 and a pulmonary cyst at an unknown age. The patient aged 14 at time of partial thyroidectomy later manifested a Sertoli-Leydig Cell Tumor at age 15. All six patients were female. CasePresentingHPO: None provided. CasePreviousTesting: thyroidectomy gnomAD: ENSG00000100697.10, https://gnomad.broadinstitute.org/gene/ENSG00000100697 Mutation Type: Frameshift, Nonsense
Tags
- MultipleDiseaseEntities
- c.3434del
- PMCID:PMC8451242
- Age:14
- gnomAD:ENSG00000100697.10
- ClinvarID:485534
- c.3452_3453del
- Mutation:Nonsense
- MultipleGeneVariants
- Age:21
- Mutation:Frameshift
- Pathogenic
- thyroidectomy
- c.988C>T
- PMID:34552563
- Frameshift
- Germline
- Cohort
- cancer
- c.5388dup
- ClinvarID:NotProvided
- c.171_172insAC
- goitre
- Age:12
- Gene:DICER1
- Nonsense
- AutosomalDominant
- Age:8
- DICER1
- ClinvarID:933007
- c.316del
- female
- goiter
Annotators
URL
-
-
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
-
DICER1 syndrome is an autosomal-dominant, pleiotropic, tumor-predisposition disorder arising from pathogenic germline variants in DICER1, which encodes an endoribonuclease integral to processing microRNAs (1).
Gene Name: DICER1 PMCID: PMC5443331 PMID: 28323992 HGNCID: not found Inheritance Pattern: autosomal dominant Disease Entity: thyroid cancer and familial multinodular doiter Mutation: germline loss-of-function mutation Zygosity: not provided Variant: c.1870C>T; p.Arg624a, c.1870C>T; p.Arg624a, c.1870C>T; p.Arg624a, c.1870C>T; p.Arg624a, c.3726C>A; p.Tyr1242a, c.3675C>G; p.Tyr1225a, c.3675C>G; p.Tyr1225a Family Information: 145 individuals with a DICER1 germline mutation and 135 controls from 48 families Case: family members used; both males and females used and no significant differences seen among sex; ages range from 20-40 with carriers being significantly younger than controls; no significant differences seen among ethnicity but participants located from the US, UK, and Great Britain CasePresentingHPOs: thyroid cancer or MNG diagnosis common to those with a DICER! mutation but with no chemotherapy or radiation treatment yet CasePreviousTesting: tested levels of thyroid-stimulating hormone, thyroxine, thyroxine-binding globulin, and serum albumin; thyroid palpation; thyroid ultrasound; Sanger or next-generation sequencing assays gnomAD: n/a Mutation Type: missense
Tags
- DiseaseEntity:thyroidcancerandfamilialmultinodulardoiter
- Zygosity:notprovided
- Mutation:germlineloss-of-functionmutation
- PMCID:PMC5443331
- Gene:DICER1
- FamilyInformation:145individualswithaDICER1germlinemutationand135controlsfrom48families
- MutationType:missense
- HGNCID:notfound
- PMID:28323992
- Variant: c.1870C>T; p.Arg624a, c.1870C>T; p.Arg624a, c.1870C>T; p.Arg624a, c.1870C>T; p.Arg624a, c.3726C>A; p.Tyr1242a, c.3675C>G; p.Tyr1225a, c.3675C>G; p.Tyr1225a
- InheritancePattern:autosomaldominant
Annotators
URL
-
-
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
-
Embryonal rhabdomyosarcoma (ERMS) of the uterus has recently been shown to frequently harbor DICER1 mutations.
HGNCID:
Tags
- Mutation: c.4420A>G
- Mutation: c.3580delA
- Zygosity: Some Cases displayed homozygosity
- Inheritance Pattern: Non- inheritance(DNA methylation)
- Disease Entity: Embryonal rhabdomyosarcoma (ERMS)
- PMID (PubMed ID): 33846547
- Mutation: 5428 G>C
- Family Information: not identified
- pathogenicity: only 2 of 17 patients died from disease
- case mut: f 28-67
- case wt: m&f 0.5-19
- Mutation: c.5438 A> C
- Mutation: c.5125G > A
- Variant: Clinvar ID not identified
- GeneName: DICER1
- Mutation: c5113G>A
- Mutation: c.4267G>T
- Mutation: c.5428G>T
Annotators
URL
-
- Apr 2022
-
www.sciencedirect.com www.sciencedirect.com
-
Payne, R. P., Longet, S., Austin, J. A., Skelly, D. T., Dejnirattisai, W., Adele, S., Meardon, N., Faustini, S., Al-Taei, S., Moore, S. C., Tipton, T., Hering, L. M., Angyal, A., Brown, R., Nicols, A. R., Gillson, N., Dobson, S. L., Amini, A., Supasa, P., … Zawia, A. A. T. (2021). Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine. Cell, 184(23), 5699-5714.e11. https://doi.org/10.1016/j.cell.2021.10.011
-
-
twitter.com twitter.com
-
Edward Nirenberg 🇺🇦 [@ENirenberg]. (2021, November 30). This is also not limited to the vaccine- any infection we encounter will do the same thing. It’s how we evolved to get around a massive genetic and bioenergetic challenge and it’s brilliant and it’s happening all the time regardless of any vaccines we get. [Tweet]. Twitter. https://twitter.com/ENirenberg/status/1465698637434933254
-
-
www.graphpad.com www.graphpad.com
-
difference between SD and SEM
-
-
towardsdatascience.com towardsdatascience.com
-
In this case, for a test to be statistically significant, p-value must be lower than 0.05.
statistical significance should be less than 5%
tf your confidence that the results are not due to chance is 95%
-
-
www.stat.colostate.edu www.stat.colostate.edu
-
We are 99% confident that the true average “attitude” difference betweenliving environments is between 1.32 and 7.88. At a significance level of 0.01we can say that living in a minority environment is associated with higherscore
99% confident that the true average (result) is between these two numbers;
at 1% (0.01) significance, we can scientifically assume there is a causal relationship
-
- Mar 2022
-
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
-
Bellesi, S., Metafuni, E., Hohaus, S., Maiolo, E., Marchionni, F., D’Innocenzo, S., La Sorda, M., Ferraironi, M., Ramundo, F., Fantoni, M., Murri, R., Cingolani, A., Sica, S., Gasbarrini, A., Sanguinetti, M., Chiusolo, P., & De Stefano, V. (2020). Increased CD95 (Fas) and PD-1 expression in peripheral blood T lymphocytes in COVID-19 patients. British Journal of Haematology, 191(2), 207–211. https://doi.org/10.1111/bjh.17034
-
-
twitter.com twitter.com
-
Eric Topol. (2022, February 28). A multimodal #AI study of ~54 million blood cells from Covid patients @YaleMedicine for predicting mortality risk highlights protective T cell role (not TH17), poor outcomes of granulocytes, monocytes, and has 83% accuracy https://nature.com/articles/s41587-021-01186-x @NatureBiotech @KrishnaswamyLab https://t.co/V32Kq0Q5ez [Tweet]. @EricTopol. https://twitter.com/EricTopol/status/1498373229097799680
-
-
deadline.com deadline.com
-
https://deadline.com/2022/03/discovery-sets-board-of-directors-warnermedia-merger-1234979430/
New board for Warner Bros. Discovery after $43 billion merger.
-
-
twitter.com twitter.com
-
Anthony J Leonardi, PhD, MS. (2022, February 28). Damn, nice find https://t.co/cJRhB2k4zH [Tweet]. @fitterhappierAJ. https://twitter.com/fitterhappierAJ/status/1498113886846914567
-
- Feb 2022
-
www.nature.com www.nature.com
-
Hall, V. G., Ferreira, V. H., Wood, H., Ierullo, M., Majchrzak-Kita, B., Manguiat, K., Robinson, A., Kulasingam, V., Humar, A., & Kumar, D. (2022). Delayed-interval BNT162b2 mRNA COVID-19 vaccination enhances humoral immunity and induces robust T cell responses. Nature Immunology, 1–6. https://doi.org/10.1038/s41590-021-01126-6
-
- Jan 2022
-
www.ijidonline.com www.ijidonline.com
-
Paolucci, S., Cassaniti, I., Novazzi, F., Fiorina, L., Piralla, A., Comolli, G., Bruno, R., Maserati, R., Gulminetti, R., Novati, S., Mojoli, F., Baldanti, F., Bruno, R., Mondelli, M., Brunetti, E., Matteo, A. D., Seminari, E., Maiocchi, L., Zuccaro, V., … Ferrari, A. (2021). EBV DNA increase in COVID-19 patients with impaired lymphocyte subpopulation count. International Journal of Infectious Diseases, 104, 315–319. https://doi.org/10.1016/j.ijid.2020.12.051
-
-
sheetstutorial.com sheetstutorial.com
-
How to do t test in google sheets
T-test tutorial
-
-
www.frontiersin.org www.frontiersin.org
-
Townsend, L., Dyer, A. H., Naughton, A., Kiersey, R., Holden, D., Gardiner, M., Dowds, J., O’Brien, K., Bannan, C., Nadarajan, P., Dunne, J., Martin-Loeches, I., Fallon, P. G., Bergin, C., O’Farrelly, C., Cheallaigh, C. N., Bourke, N. M., & Conlon, N. (2021). Longitudinal Analysis of COVID-19 Patients Shows Age-Associated T Cell Changes Independent of Ongoing Ill-Health. Frontiers in Immunology, 12. https://www.frontiersin.org/article/10.3389/fimmu.2021.676932
-
-
www.agenciasinc.es www.agenciasinc.es
-
Los linfocitos T no nos salvarán del coronavirus, pero ayudarán a resolver el puzle inmunitario. (n.d.). Agencia SINC. Retrieved January 17, 2022, from https://www.agenciasinc.es/Reportajes/Los-linfocitos-T-no-nos-salvaran-del-coronavirus-pero-ayudaran-a-resolver-el-puzle-inmunitario
-
-
www.theguardian.com www.theguardian.com
-
Halliday, J., & correspondent, J. H. N. of E. (2022, January 17). ‘Christmas was awful’: On the Omicron frontline at the Royal Preston hospital. The Guardian. https://www.theguardian.com/world/2022/jan/17/christmas-was-awful-on-the-omicron-frontline-at-the-royal-preston-hospital
-
-
twitter.com twitter.com
-
Anthony J Leonardi, PhD, MS. (2022, January 4). Wow. 17 years of T cell immunity guys. Looks like it works as advertised. Https://t.co/bkSizFXK49 [Tweet]. @fitterhappierAJ. https://twitter.com/fitterhappierAJ/status/1478392475240869899
-
-
twitter.com twitter.com
-
ReconfigBehSci on Twitter: ‘T cell immunologist getting very upset at people arguing that high levels of transmission are a good thing’ / Twitter. (n.d.). Retrieved 12 January 2022, from https://twitter.com/SciBeh/status/1481178244678402048
-
-
drive.google.com drive.google.com
-
In his article, Gorbachev says that perestroika was meant for the people and that its goal was to emancipate human beings to give people ownership of their lives and of their country. This stood out to me because the believed it was right to give people freedom which is a great point.
-
- Dec 2021
-
www.nature.com www.nature.com
-
Adamo, S., Michler, J., Zurbuchen, Y., Cervia, C., Taeschler, P., Raeber, M. E., Sain, S. B., Nilsson, J., Moor, A. E., & Boyman, O. (2021). Signature of long-lived memory CD8+ T cells in acute SARS-CoV-2 infection. Nature, 1–9. https://doi.org/10.1038/s41586-021-04280-x
-
-
www.nature.com www.nature.com
-
Heitmann, J. S., Bilich, T., Tandler, C., Nelde, A., Maringer, Y., Marconato, M., Reusch, J., Jäger, S., Denk, M., Richter, M., Anton, L., Weber, L. M., Roerden, M., Bauer, J., Rieth, J., Wacker, M., Hörber, S., Peter, A., Meisner, C., … Walz, J. S. (2021). A COVID-19 peptide vaccine for the induction of SARS-CoV-2 T cell immunity. Nature, 1–9. https://doi.org/10.1038/s41586-021-04232-5
-
-
www.bmj.com www.bmj.com
-
Mahase, E. (2021). Covid-19: Antibody boost after third dose varies greatly by vaccine, study finds. BMJ, 375, n3011. https://doi.org/10.1136/bmj.n3011
-
- Nov 2021
-
www.facebook.com www.facebook.com
-
docdrop.org docdrop.org
-
I have used the Oxford text of T. W. Allen, 2nd edition, and followed itexcept in a very few places
The source of the translation of the Odyssey by Richmond Lattimore is the 2nd edition of the Oxford text of T. W. Allen.
-
-
certificates.creativecommons.org certificates.creativecommons.org
-
Public Knowledge resource
spoiler: there is also an example about licensing a T-Rex shower nozzle 3-D printed.
-
- Sep 2021
-
twitter.com twitter.com
-
John Burn-Murdoch. (2021, August 23). NEW: in the last couple of weeks there have a lot of new studies out assessing vaccine efficacy, many of which have touched on the question of waning immunity. Unsurprisingly, these have prompted a lot of questions. Time for a thread to summarise what we do and don’t know: [Tweet]. @jburnmurdoch. https://twitter.com/jburnmurdoch/status/1429878189011111936
-
- Jul 2021
-
twitter.com twitter.com
-
Thushan de Silva on Twitter. (n.d.). Twitter. Retrieved 29 July 2021, from https://twitter.com/Thushan_deSilva/status/1418511974435115011
-
-
www.nejm.org www.nejm.org
-
Barouch, Dan H., Kathryn E. Stephenson, Jerald Sadoff, Jingyou Yu, Aiquan Chang, Makda Gebre, Katherine McMahan, et al. “Durable Humoral and Cellular Immune Responses 8 Months after Ad26.COV2.S Vaccination.” New England Journal of Medicine 0, no. 0 (July 14, 2021): null. https://doi.org/10.1056/NEJMc2108829.
-
-
www.doers3.org www.doers3.org
Tags
Annotators
URL
-
- Jun 2021
-
poseidon01.ssrn.com poseidon01.ssrn.com
-
Parry, H. M., Tut, G., Faustini, S., Stephens, C., Saunders, P., Bentley, C., Hilyard, K., Brown, K., Amirthalingam, G., Charlton, S., Leung, S., Chiplin, E., Coombes, N. S., Bewley, K. R., Penn, E. J., Rowe, C., Otter, A., Watts, R., D’Arcangelo, S., … Moss, P. (2021). BNT162b2 Vaccination in People Over 80 Years of Age Induces Strong Humoral Immune Responses with Cross Neutralisation of P.1 Brazilian Variant. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.3816840
-
- May 2021
-
hiphopfoundations.org hiphopfoundations.org
-
James Brown
"Funky President" appears on the Grand Theft Auto: San Andreas soundtrack on the Master Sounds 98.3 station.
https://genius.com/James-brown-funky-president-people-its-bad-lyrics
-
- Apr 2021
-
twitter.com twitter.com
-
evaluation in the margins
Dr. Laura Gibbs is one of the most inspiring educators I know.
-
-
static1.squarespace.com static1.squarespace.com
-
are called mother.
This appreciation would be exceptional in terms of respect.
-
- Mar 2021
-
www.nytimes.com www.nytimes.com
-
In the late 1960s and early ’70s, he liked to tweak his critics by wearing a T-shirt that read “Minor Regional Novelist.”
I want a shirt like this!
-
-
science.sciencemag.org science.sciencemag.org
-
Buss, Lewis F., Carlos A. Prete, Claudia M. M. Abrahim, Alfredo Mendrone, Tassila Salomon, Cesar de Almeida-Neto, Rafael F. O. França, et al. ‘Three-Quarters Attack Rate of SARS-CoV-2 in the Brazilian Amazon during a Largely Unmitigated Epidemic’. Science 371, no. 6526 (15 January 2021): 288–92. https://doi.org/10.1126/science.abe9728.
-
- Feb 2021
-
www.forbes.com www.forbes.com
-
When T-Cells are activated they release cytokines (yes, that cytokine), which trigger additional T-Cells to be made, which then release even more cytokines. One type of T-cells that are created are called cytotoxic T-cells. Cytotoxic T-cells are the cells that are able to roam the body and mercy kill infected cells who are chemically calling out to be killed and ideally to stop the increased production of viruses like COVID-19.
-
-
twitter.com twitter.com
-
ReconfigBehSci. (2020, November 21). RT @DrEricDing: Good question for immunologists like @michaelmina_lab @VirusesImmunity and @PeterHotez. Https://t.co/Rs1zaUPznm [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1334804615842439170
-
- Jan 2021
-
jaewon1013.github.io jaewon1013.github.io
-
Learners’ practices, for example, should develop from low-level procedures such as sharing initial ideas to mid-level comparing and evaluatingsequences and eventually toward high-level challenging/debating and synthesizingroutines.
The surface to in-depth learning. Related to Expansive framing written by Andrews et al.
-
identify invariant (i.e., constant) characteristics of subsequent transfer domains
The "bone" of the body. In the design of social annotation activities, what are the bones?
-
- Dec 2020
-
www.investopedia.com www.investopedia.comT-Test1
-
Essentially, a t-test allows us to compare the average values of the two data sets and determine if they came from the same population.
Comparing datasets to see if they came from the same population.
Tags
Annotators
URL
-
- Oct 2020
-
www.ibm.com www.ibm.com
-
The GROUPS subcommand specifies an unknown variable or a long string variable.
The GROUPS subcommand specifies an unknown variable or a long string variable.
-
- Sep 2020
-
-
Doshi, P. (2020). Covid-19: Do many people have pre-existing immunity? BMJ, 370. https://doi.org/10.1136/bmj.m3563
-
-
ecourse.auca.kg ecourse.auca.kgFYS.pdf2
-
Come, Shamhat, 1 will fix your destiny,
It shows the confident.
-
[who] knew ... , was wise in all matters!
Was the author meant Gilgamesh?
-
-
www.nature.com www.nature.com
-
Le Bert, N., Tan, A. T., Kunasegaran, K., Tham, C. Y. L., Hafezi, M., Chia, A., Chng, M. H. Y., Lin, M., Tan, N., Linster, M., Chia, W. N., Chen, M. I.-C., Wang, L.-F., Ooi, E. E., Kalimuddin, S., Tambyah, P. A., Low, J. G.-H., Tan, Y.-J., & Bertoletti, A. (2020). SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls. Nature, 584(7821), 457–462. https://doi.org/10.1038/s41586-020-2550-z
-
-
www.imperial.ac.uk www.imperial.ac.uk
-
T cell immunity: What is it and how does it help to protect us from COVID-19? | Imperial News | Imperial College London. (n.d.). Imperial News. Retrieved September 18, 2020, from https://www.imperial.ac.uk/news/201833/cell-immunity-what-does-help-protect/
-
- Aug 2020
-
science.sciencemag.org science.sciencemag.org
-
Mateus, J., Grifoni, A., Tarke, A., Sidney, J., Ramirez, S. I., Dan, J. M., Burger, Z. C., Rawlings, S. A., Smith, D. M., Phillips, E., Mallal, S., Lammers, M., Rubiro, P., Quiambao, L., Sutherland, A., Yu, E. D., Antunes, R. da S., Greenbaum, J., Frazier, A., … Weiskopf, D. (2020). Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans. Science. https://doi.org/10.1126/science.abd3871
-
-
www.sciencemag.org www.sciencemag.org
-
LeslieMay. 14, M., 2020, & Pm, 9:00. (2020, May 14). T cells found in COVID-19 patients ‘bode well’ for long-term immunity. Science | AAAS. https://www.sciencemag.org/news/2020/05/t-cells-found-covid-19-patients-bode-well-long-term-immunity
-
-
www.nytimes.com www.nytimes.com
-
Mandavilli, A. (2020, June 18). You May Have Antibodies After Coronavirus Infection. But Not for Long. The New York Times. https://www.nytimes.com/2020/06/18/health/coronavirus-antibodies.html
-
-
medrxiv.org medrxiv.org
-
Ferretti, A. P., Kula, T., Wang, Y., Nguyen, D. M., Weinheimer, A., Dunlap, G. S., Xu, Q., Nabilsi, N., Perullo, C. R., Cristofaro, A. W., Whitton, H. J., Virbasius, A., Olivier, K. J., Baiamonte, L. B., Alistar, A. T., Whitman, E. D., Bertino, S. A., Chattopadhyay, S., & MacBeath, G. (2020). COVID-19 Patients Form Memory CD8+ T Cells that Recognize a Small Set of Shared Immunodominant Epitopes in SARS-CoV-2. MedRxiv, 2020.07.24.20161653. https://doi.org/10.1101/2020.07.24.20161653
-
-
twitter.com twitter.com
-
Benjamin Meyer on Twitter: “1. Since there was a huge discussion about T-cell mediated immunity following the Lancet comment on seroprevalence by @EckerleIsabella and me, I’d like to share my thoughts on this in the following thread:” / Twitter. (n.d.). Twitter. Retrieved July 8, 2020, from https://twitter.com/BenjaminMeyer85/status/1280257221587320835
-
-
-
Xu, G., Qi, F., Li, H., Yang, Q., Wang, H., Wang, X., Liu, X., Zhao, J., Liao, X., Liu, Y., Amit, I., Liu, L., Zhang, S., & Zhang, Z. (2020). The differential immune responses to COVID-19 in peripheral and lung revealed by single-cell RNA sequencing. MedRxiv, 2020.08.15.20175638. https://doi.org/10.1101/2020.08.15.20175638
-
- Jun 2020
-
twitter.com twitter.com
-
Crotty, S. (2020, May 14). "Our new paper rapidly studied T cell + antibody immune responses in average COVID-19 cases. This is good news in multiple ways, including coronavirus vaccines. @ljiresearch cell.com/cell/fulltext/..." Twitter. https://twitter.com/profshanecrotty/status/1261052353773363200
-
- May 2020
-
www.sciencedirect.com www.sciencedirect.com
-
Grifoni, A., Weiskopf, D., Ramirez, S. I., Mateus, J., Dan, J. M., Moderbacher, C. R., Rawlings, S. A., Sutherland, A., Premkumar, L., Jadi, R. S., Marrama, D., de Silva, A. M., Frazier, A., Carlin, A., Greenbaum, J. A., Peters, B., Krammer, F., Smith, D. M., Crotty, S., & Sette, A. (2020). Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals. Cell, S0092867420306103. https://doi.org/10.1016/j.cell.2020.05.015
-
- Apr 2020
-
blogs.bmj.com blogs.bmj.com
-
Don’t touch the T-Zone—How to block a key pathway to infection with SARS-CoV-2. (2020, April 3). The BMJ. https://blogs.bmj.com/bmj/2020/04/03/dont-touch-the-t-zone-how-to-block-a-key-pathway-to-infection-with-sars-cov-2/
-
- Oct 2019
-
stackoverflow.com stackoverflow.com
Tags
Annotators
URL
-
-
stackoverflow.com stackoverflow.com
-
stackoverflow.com stackoverflow.com
-
Let's make the example even easier. function convertDate<T extends string | undefined>(isoDate?: string): T { return undefined } 'undefined' is assignable to the constraint of type 'T' Means: What you return in the function (undefined), matches the constraints of your generic type parameter T (extends string | undefined). , but 'T' could be instantiated with a different subtype of constraint 'string | undefined'. Means: TypeScript does not consider that as safe. What if you defined your function like this at compile time: // expects string return type according to generics // but you return undefined in function body const res = convertDate<string>("2019-08-16T16:48:33Z") Then according to your signature, you expect the return type to be string. But at runtime that is not the case! This discrepancy that T can be instantiated with a different subtype (here string) than you return in the function (undefined) is expressed with the TypeScript error.
-
-
www.typescriptlang.org www.typescriptlang.org
-
Based on examples given in https://github.com/Microsoft/TypeScript/issues/29049
-
-
stackoverflow.com stackoverflow.com
-
Both of the below are valid as far as T extends (...args: any[]) => any goes logFn((a, b) => a + b) logFn((a, b, c) => c) But if you refer back to the example I gave, the inner definition as: return (a, b) => fn(a, b); So option 2. will throw an error here, which is why typescript is warning you about it.
-
-
github.com github.com
-
In the body of the function you have no control over the instantiation by the calling context, so we have to treat things of type T as opaque boxes and say you can't assign to it. A common mistake or misunderstanding was to constraint a type parameter and then assign to its constraint, for example: function f<T extends boolean>(x: T) { x = true; } f<false>(false); This is still incorrect because the constraint only restricts the upper bound, it does not tell you how precise T may really be.
-
-
stackoverflow.com stackoverflow.com
-
P can't be assigned {}, since the Generic Type P can be a more defined (or restricted) type.
-
-
stackoverflow.com stackoverflow.com
-
you can have a Type that is more specific than a boolean like this
-