77 Matching Annotations
  1. Nov 2022
    1. I'm pretty much done thinking about "tools for thought". It quickly becomes an infinity of navel gazing and a complete waste of time. It's an easy topic for budding "influencers" because you don't actually need to know anything. All they need is to spend some time with a new bit of software and tell people how they should use it and the next thing you know they're selling an online course via their budding YouTube channel.

      scathing, but broadly true...

  2. Oct 2022
    1. If you're trying out @tana_inc and are not on the slack... why not?? There are so many talented people coming up with awesome workflows

      https://twitter.com/syncretizm/status/1581264527336669184

      So many in the tools for thought space either have shiny object syndrome or are focusing on "workflows". Eventually you have to quit looking at and building workflows to actually get some work done.

  3. Aug 2022
    1. What is more, these advances have notnarrowed the gap between what is known and what can be seen to lie beyond thescope of present understanding and technique; rather, each advance has madeit clear that these intellectual horizons are far more remote than was heretoforeimagined.
    1. Since 2016, American diplomats in Cuba, Russia, China and elsewhere have experienced "Havana Syndrome," associated with mysterious neurological and brain injuries thought to be inflicted by unknown high-powered microwave or targeted sonic energy systems. Sound wave transmitters are not only psychologically toxic but can cause pain and dizziness, burns, irreversible damage to inner ears and possibly neurological and internal injuries.
  4. Jul 2022
    1. Harold Jarche looked at his most visited blog postings over the years, and concludes his blog conforms to Sturgeon’s Revelation that 90% of everything is crap. I recognise much of what Harold writes. I suspect this is also what feeds impostor syndrome. You see the very mixed bag of results from your own efforts, and how most of it is ‘crap’. The few ‘hits’ for which you get positive feedback are then either ‘luck’ or should be normal, not sparse. Others of course forget most if not all of your less stellar products and remember mostly the ones that stood out. Only you are in a position to compare what others respond to with your internal perspective.

      The cumulative effect of one's perception of Sturgeon's law may be a driving force underlying imposter syndrome.

      While one see's the entirety of their own creation process and realizes that only a small fraction of it is truly useful, it's much harder seeing only the finished product of others. The impression one is left with by availability heuristic is that there are thousands of geniuses in the world with excellent, refined products or ideas while one's own contribution is miniscule in comparison.


      Contrast this with Matt Ridley's broad perspective in The Rational Optimist which shows the power of cumulative breeding and evolution of ideas. One person can make their own stone hand axe, but no one person can make their own toaster oven or computer mouse alone.

      Link to: - lone genius myth (eg. Einstein's special relativity did not spring fully formed from the head of Zeus, there was a long train of work and thought which we don't see the context of)

    1. My Fortran professor gave me a low mark because I used a lookup table for octal to binary conversion, instead of using division and modulo.
    1. As the Intergovernmental Panel on Climate Change says in its October 2018 report, keeping global warming below 1.5 C “is possible within the laws of chemistry and physics” but will require “unprecedented changes” before 2030.

      The increasingly dire warnings of scientists are unfortunately increasingly normalized as the unintended consequences of media on human evolutionary propensity to adapt to environmental challenges - the so called "Boiling Frog Syndrome".

  5. May 2022
    1. Common Pitfalls to Avoid When Choosing Your App

      What are the common pitfalls when choosing a note taking application or platform?

      Own your data

      Prefer note taking systems that don't rely on a company's long term existence. While Evernote or OneNote have been around for a while, there's nothing to say they'll be around forever or even your entire lifetime. That shiny new startup note taking company may not gain traction in the market and exist in two years. If your notes are trapped inside a company's infrastructure and aren't exportable to another location, you're simply dead in the water. Make sure you have a method to be able to export and own the raw data of your notes.

      Test driving many

      and not choosing or sticking with one (or even a few)<br /> Don't get stunned into inaction by the number of choices.

      Shiny object syndrome

      is the situation where people focus all attention on something that is new, current or trendy, yet drop this as soon as something new takes its place.<br /> There will always be new and perhaps interesting note taking applications. Some may look fun and you'll be tempted to try them out and fragment your notes. Don't waste your time unless the benefits are manifestly clear and the pathway to exporting your notes is simple and easy. Otherwise you'll spend all your time importing/exporting and managing your notes and not taking and using them. Paper and pencil has been around for centuries and they work, so at a minimum do this. True innovation in this space is exceedingly rare, and even small affordances like the ability to have [[wikilinks]] and/or bi-directional links may save a few seconds here and there, in the long run these can still be done manually and having a system far exceeds the value of having the best system.

      (Relate this to the same effect in the blogosphere of people switching CMSes and software and never actually writing content on their website. The purpose of the tool is using it and not collecting all the tools as a distraction for not using them. Remember which problem you're attempting to solve.)

      Future needs and whataboutisms

      Surely there will be future innovations in the note taking space or you may find some niche need that your current system doesn't solve. Given the maturity of the space even in a pen and paper world, this will be rare. Don't worry inordinately about the future, imitate what has worked for large numbers of people in the past and move forward from there.

      Others? Probably...

    1. software engineers who do web development are by far among the worst at actually evaluating solutions based on their engineering merit

      There's plenty of irrationality to be found in opposing camps, too. I won't say that it's actually worse (because it's not), but it's definitely a lot more annoying, because it usually also carries overtones that there's a sort of well-informed moral and technological high ground—when it turns out it's usually just a bunch of second panel thinkers who themselves don't even understand computers (incl. compilers, system software, etc.) very well.

      This is what makes it hard to have discussions about reforming the practices in mainstream Web development. The Web devs are doing awful things, but at least ~half of the criticism that these devs are actually exposed to ends up being junk because lots of the critics unfortunately just have no fucking idea what they're talking about and are nowhere near the high ground they think they're standing on—often taking things for granted that just don't make sense when actually considered in terms of the technological uppercrust that they hope to invoke. Just a kneejerk "browser = bad" association from people who can't meaningfully distinguish between JS (the language), browser APIs, and the NPM corpus (though most NPM programmers are usually guilty of exactly the same...).

      It's a very "the enemy of my enemy is not my friend" sort of thing.

    1. DICER1 syndrome is an autosomal-dominant,pleiotropic, tumor-predisposition disorder arisingfrom pathogenic germline variants in DICER1, whichencodes an endoribonuclease integral to processingmicroRNAs

      DICER1 is the gene name. PubMed ID, HGCNCID, and Variant: I can't find Inheritance Pattern: autosomal-dominant The disease entity: DICER1 syndrome The type of mutation: germline. Zygosity: not known. Family Information: a family was used, DICER1 carriers, and non DICER1 variant used, some of the family members had tumors from DICER1 Case Information: mean age is 34, the range of age is 18.6 to 43 years, male, and female used, ethnicity can't find Case Presenting HPO: cancer testing, chemotherapy, radiotherapy gnomeAD: 9.2,8.3.2 Mutation type: Pleiotropic, loss of function, missense

  6. Apr 2022
    1. DICER1 syndrome is a rare genetic disorder that predisposes individuals to multiple cancer types

      GeneName: DICER1 PMID (PubMed ID): 29762508 HGNCID: Unavailable Inheritance Pattern: Autosomal Dominant Disease Entity: cancer, rare genetic disorder, pleuroplumonary blastomas, cystic nephroma, rhabdomyosarcoma, multinodular goiter, thyroid cancer, overian Sertoli-Leydig cell tumors, and other meoplasias Mutations: Germline mutations or Somatic mutations Zygosity: Heterozygosity Variant: unregistered Family Information: Cystic nephromas has been reported in approximately 12% of children with pleuripulmonary blastomas or those with a family member with cystic nephroma. Patient with two DICER1 mutations and several of his family members shared these mutations. All members developed a least one type of tumor with differing origins. The patient was an 11-year old boy with a rare Hodgkin lymphoma with DICER1 in 2016. (c.5299delC and c.4616C>T).

  7. Feb 2022
    1. These study guides, which neglect everything before a writingassignment is given, are a little bit like financial advisors who discusshow 65-year-olds can save for retirement. At this point you would bebetter off curbing your enthusiasm (which is exactly what one of themost often sold study guides in Germany recommends: first, loweryour expectations on quality and insight).

      A side benefit of a growing set of notes as an academic is that one has a visible repository of knowledge and ideas as well as fascinating questions which, while they may reveal how much one doesn't know, it will make it apparent how much one does know and thereby mitigate one's feelings of imposter syndrome.

    2. Good students, on the other hand, constantly raise the bar forthemselves as they focus on what they haven’t learned andmastered yet. This is why high achievers who have had a taste ofthe vast amount of knowledge out there are likely to suffer from whatpsychologists call imposter syndrome, the feeling that you are notreally up to the job, even though, of all people, they are (Clance andImes 1978; Brems et al. 1994).

      He's saying here that smart, high achievers are more likely to suffer from imposter syndrome specifically because they've read more broadly and know what they're doing.

      Does the psychology research indicate this? Is there a higher incidence of imposter syndrome at the higher end of the spectrum in part because ones' knowledge of the Known Unknown Framework is dramatically expanded?

      Look into these sources for more detail on this question.

    1. Deepti Gurdasani. (2022, January 29). Going to say this again because it’s important. Case-control studies to determine prevalence of long COVID are completely flawed science, but are often presented as being scientifically robust. This is not how we can define clinical syndromes or their prevalence! A thread. [Tweet]. @dgurdasani1. https://twitter.com/dgurdasani1/status/1487366920508694529

  8. Jan 2022
    1. triad

      triad of serotonin syndrome: altered mental status, neuromuscular abnormalities, autonomic hyperactivity

  9. Dec 2021
    1. Among the most eloquent commentaries on this wholephenomenon is to be found in a private letter written by BenjaminFranklin to a friend:When an Indian Child has been brought up among us,taught our language and habituated to our Customs, yet ifhe goes to see his relations and make one Indian Ramblewith them there is no persuading him ever to return, andthat this is not natural merely as Indians, but as men, isplain from this, that when white persons of either sexhave been taken prisoner young by the Indians, and livedawhile among them, tho’ ransomed by their Friends, andtreated with all imaginable tenderness to prevail withthem to stay among the English, yet in a Short time theybecome disgusted with our manner of life, and the careand pains that are necessary to support it, and take thefirst opportunity of escaping again into the Woods, fromwhence there is no reclaiming them. One instance Iremember to have heard, where the person was to bebrought home to possess a good Estate; but finding somecare necessary to keep it together, he relinquished it to ayounger brother, reserving to himself nothing but a gunand match-Coat, with which he took his way again to theWilderness.30

      Franklin, Benjamin. 1961 [1753]. Letter to Peter Collinson, 9 May 1753. In Leonard W. Labaree (ed.), The Papers of Benjamin Franklin. New Haven, CT and London: Yale University Press, vol. 4, pp. 481–3.

      Is Stockholm syndrome a temporary or permanent condition? Likely that it's not permanent and that basic lifeways may win out in a switch of lifeways.

    2. The colonial history of Northand South America is full of accounts of settlers, captured oradopted by indigenous societies, being given the choice of wherethey wished to stay and almost invariably choosing to stay with thelatter.

      How is this to be interpreted against the idea of Stockholm syndrome, a condition in which hostages develop a psychological bond with their captors during captivity?

      Were these people actually captives? Could there have been an effect beyond the idea of one way of life being better than another? Are there example in the other direction?

      There's the example in Chagnon's Science paper (1998: 990) in which the nursing student wanted Western culture to visit his Yanomami peoples.

      There are also numerous examples of indigenous Americans being captured by Americans and forced to live a life they didn't want to or choose.

  10. Nov 2021
  11. Oct 2021
    1. But when our hypothetical Blub programmer looks in the other direction, up the power continuum, he doesn't realize he's looking up.

      We have a word for this: "sophomoric".

  12. Sep 2021
  13. Jul 2021
  14. Jun 2021
    1. Mike: That was going on high school. I think it was my freshman year, because like I said man, it's just all these things that happen to you, there's just only so much you could take to where you're like, "You know what? Eff it." You're just done with everybody and you're just like, "You know what? If life paid me back like this, then why should I care?" You know what I mean? And it makes me feel like inferior at times.Mike: So yeah, I feel like it was around my freshman year, everything started going downhill, because I used to be in events, classes, and all my teachers loved me. I would have conversations like this with my teachers and they'd be amazed sometimes like, "Wow, this kid has so much insight. So much to talk about." And they would always encourage me, but the thing about it is I wouldn't feel like that.

      Time in the US, School, High School, Struggling/ Suspension/ Dropping Out

  15. May 2021
    1. I have received a lot of positive feedback for noting my epistemic status and effort at the top of my posts. This is hilarious, because I originally started using these as a hack in order to publish half-baked ideas that I'd otherwise not feel comfortable sharing.

      This is an interesting hack for getting one to hit the publish button.

      I wonder if people have renamed the "publish" button in their CMS to make hitting it easier?

      My own anecdotal evidence is that hitting it often can certainly make it seem trivial, particularly if one is posting their status updates to their site along with everything else.

      <small><cite class='h-cite via'> <span class='p-author h-card'>Maggie Appleton</span> in A Brief History & Ethos of the Digital Garden (<time class='dt-published'>05/28/2021 18:08:16</time>)</cite></small>

  16. Apr 2021
  17. Mar 2021
    1. People diagnosed with REM sleep behaviour syndrome have an increased risk of developing Parkinson's disease.

      According to this statement, those who are diagnosed with RME sleep behavior syndrome have an increased risk of developing Parkinson’s disease. A number of questions arise from this statement.

      • What are the characteristics of REM sleep behavior syndrome? How does it manifest itself? How often does it manifest itself? Do those individuals in which it manifests itself more frequently have an increased chance of developing Parkinson’s disease?
      • What is the neurological mechanism that is causing REM sleep behavior syndrome? Is the mechanism that is causing this the actual cause of the reduction of dopamine production that is characteristic of Parkinson’s disease?
  18. Feb 2021
    1. However, most notably, COVID-19 patients are most often dying of acute respiratory distress syndrome (ARDS), which indicates that COVID-19 related cytokine storms, like the virus, are focused in the lower lung. This leads to the instances of acute pneumonia and the need for intubation and ventilator use.
  19. Oct 2020
    1. The solution to imposter syndrome is to see that you are one. When I first wrote about how useful it is to remember that everyone is totally just winging it, all the time, we hadn’t yet entered the current era of leaderly incompetence (Brexit, Trump, coronavirus). Now, it’s harder to ignore. But the lesson to be drawn isn’t that we’re doomed to chaos. It’s that you – unconfident, self-conscious, all-too-aware-of-your-flaws – potentially have as much to contribute to your field, or the world, as anyone else.
  20. Aug 2020
    1. Consiglio, C. R., Cotugno, N., Sardh, F., Pou, C., Amodio, D., Zicari, S., Ruggiero, A., Pascucci, G. R., Rodriguez, L., Santilli, V., Tan, Z., Eriksson, D., Wang, J., Lakshmikanth, T., Marchesi, A., Lakshmikanth, T., Campana, A., Villani, A., Rossi, P., … Brodin, P. (2020). The Immunology of Multisystem Inflammatory Syndrome in Children with COVID-19. MedRxiv, 2020.07.08.20148353. https://doi.org/10.1101/2020.07.08.20148353

    1. Chen, Y., Yang, W.-H., Huang, L.-M., Wang, Y.-C., Yang, C.-S., Liu, Y.-L., Hou, M.-H., Tsai, C.-L., Chou, Y.-Z., Huang, B.-Y., Hung, C.-F., Hung, Y.-L., Chen, J.-S., Chiang, Y.-P., Cho, D.-Y., Jeng, L.-B., Tsai, C.-H., & Hung, M.-C. (2020). Inhibition of Severe Acute Respiratory Syndrome Coronavirus 2 main protease by tafenoquine in vitro. BioRxiv, 2020.08.14.250258. https://doi.org/10.1101/2020.08.14.250258

  21. Jul 2020
  22. Jun 2020
  23. May 2020
  24. Apr 2020
    1. Le syndrome de la dispersion est un mal universellement partagé dans de nombreux secteurs de travail, particulièrement dans les activités d’encadrement.

      Nous avons ici, la thèse de cet article, qui sera étayée par divers arguments.

  25. Feb 2020
  26. Apr 2019
  27. Oct 2018
    1. Low BP was more prevalent in subjects with upper airway resistance syndrome (UARS) (23%) than in subjects with obstructive sleep apnea syndrome (OSAS) (0.06%), parasomnia (0.7%), restless leg syndrome (0.9%), or psychological insomnia (0.9%).

      That's an extremely high rate of hypotension in UARS. This may be what I have. If UARS causes hypotension, then sleep apnea (SA) may be different because of its link to obesity.

  28. Feb 2017
  29. Oct 2016
  30. May 2016
    1. Slower metabolisms were not the only reason the contestants regained weight, though. They constantly battled hunger, cravings and binges. The investigators found at least one reason: plummeting levels of leptin. The contestants started out with normal levels of leptin. By the season’s finale, they had almost no leptin at all, which would have made them ravenous all the time. As their weight returned, their leptin levels drifted up again, but only to about half of what they had been when the season began, the researchers found, thus helping to explain their urges to eat.Leptin is just one of a cluster of hormones that control hunger, and although Dr. Hall and his colleagues did not measure the rest of them, another group of researchers, in a different project, did. In a one-year study funded by Australia’s National Health and Medical Research Council, Dr. Joseph Proietto of the University of Melbourne and his colleagues recruited 50 overweight people who agreed to consume just 550 calories a day for eight or nine weeks. They lost an average of nearly 30 pounds, but over the next year, the pounds started coming back.
  31. Aug 2015
    1. Here, on page 2, a study on infrasound conducted by Mr. Richard James is referenced. Mr. Richard James references Nina Pierpont's "Wind Turbine Syndrome" in articles he has written, namely "Wind Turbine Infra and Low-Frequency Sound: Warning Signs That Were Not Heard," see this link. Wind turbine syndrome is not a real medical syndrome, see this link and this link. In fact, Mr. Richard James and his methodologies for measuring sound has been discredited in a Michigan court, see Rick James – A Technical Discussion of His Deposition and Testimony in the Spencer / Kobetz Lawsuit.

      On page 7, we learn that Mr. Richard James trained a field technician to set up sound measuring equipment at a dozen homes within the Shirley Wind Farm. It's unclear if Mr. Richard James was present to ensure set up and staging of equipment was per professional protocol. The trained field technician is stated to live within the Shirley Wind Farm. Mr. Richard James also collected weather data using a website called wonderground.com [sic]. Note that the field technician didn't record weather data via actual observation while domiciled within the Shirley Wind Farm. Also to consider is the likelihood of gaps in the collection of data, "On many occasions, there was an observer recording the events of the turbines..." This sounds fuzzy. Brings doubt to the reliability of collected data.

      On page 13, the Brown County Board of health declares the Shirley Wind Farm a human health hazard.

      As a result of Brown County's declaration, the Governor of Wisconsin will spend $250,000 to study health effects of wind power.

  32. May 2015
    1. When we trivialize learning something new for other people, it sends a message. “This is easy. You should know how to do this. Why don’t you?” It’s demoralizing. If you see someone else struggling, let them know it will be okay and that you’ve been there too. It’s reassuring, as a beginner, to hear that the thing that feels so impossible will one day feel easy.
    2. For me, the feeling went away after I realized, like the Director of Photography, that no one else knew what to do either. I also started to listen to conference talks on my way into work as a way of improving and read a few books in my spare time. I talked to my friends about how I felt and asked for advice.
    3. “But what if I don’t know anything and really am an impostor?”
    4. I think we find it uncomfortable to talk about feeling inadequate. It feels like it’s a problem that’s unique to us or to our situation. The general idea is well-documented and has been discussed before by countless others.