4,038 Matching Annotations
  1. Nov 2021
    1. Jeffrey Barrett. (2021, October 19). Proportion of AY.4.2 (now on http://covid19.sanger.ac.uk) has been steadily increasing in England, which is a pattern that is quite different from other AY lineages. Several of them rose when there was still Alpha to displace, but none has had a consistent advantage vs other Delta. Https://t.co/mD5gQzKxgV [Tweet]. @jcbarret. https://twitter.com/jcbarret/status/1450408485829718039

    1. Dhar, M. S., Marwal, R., VS, R., Ponnusamy, K., Jolly, B., Bhoyar, R. C., Sardana, V., Naushin, S., Rophina, M., Mellan, T. A., Mishra, S., Whittaker, C., Fatihi, S., Datta, M., Singh, P., Sharma, U., Ujjainiya, R., Bhatheja, N., Divakar, M. K., … Rakshit, P. (n.d.). Genomic characterization and epidemiology of an emerging SARS-CoV-2 variant in Delhi, India. Science, 0(0), eabj9932. https://doi.org/10.1126/science.abj9932

  2. Oct 2021
    1. Singanayagam, A., Hakki, S., Dunning, J., Madon, K. J., Crone, M. A., Koycheva, A., Derqui-Fernandez, N., Barnett, J. L., Whitfield, M. G., Varro, R., Charlett, A., Kundu, R., Fenn, J., Cutajar, J., Quinn, V., Conibear, E., Barclay, W., Freemont, P. S., Taylor, G. P., … Lackenby, A. (2021). Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: A prospective, longitudinal, cohort study. The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(21)00648-4

    1. Sun, W., Liu, Y., Amanat, F., González-Domínguez, I., McCroskery, S., Slamanig, S., Coughlan, L., Rosado, V., Lemus, N., Jangra, S., Rathnasinghe, R., Schotsaert, M., Martinez, J. L., Sano, K., Mena, I., Innis, B. L., Wirachwong, P., Thai, D. H., Oliveira, R. D. N., … Palese, P. (2021). A Newcastle disease virus expressing a stabilized spike protein of SARS-CoV-2 induces protective immune responses. Nature Communications, 12(1), 6197. https://doi.org/10.1038/s41467-021-26499-y

    1. Andreano, E., Paciello, I., Piccini, G., Manganaro, N., Pileri, P., Hyseni, I., Leonardi, M., Pantano, E., Abbiento, V., Benincasa, L., Giglioli, G., De Santi, C., Fabbiani, M., Rancan, I., Tumbarello, M., Montagnani, F., Sala, C., Montomoli, E., & Rappuoli, R. (2021). Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants. Nature, 1–7. https://doi.org/10.1038/s41586-021-04117-7

    1. Tartof, S. Y., Slezak, J. M., Fischer, H., Hong, V., Ackerson, B. K., Ranasinghe, O. N., Frankland, T. B., Ogun, O. A., Zamparo, J. M., Gray, S., Valluri, S. R., Pan, K., Angulo, F. J., Jodar, L., & McLaughlin, J. M. (2021). Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: A retrospective cohort study. The Lancet, 398(10309), 1407–1416. https://doi.org/10.1016/S0140-6736(21)02183-8

    1. Siddle, K. J., Krasilnikova, L. A., Moreno, G. K., Schaffner, S. F., Vostok, J., Fitzgerald, N. A., Lemieux, J. E., Barkas, N., Loreth, C., Specht, I., Tomkins-Tinch, C. H., Silbert, J., Schaeffer, B., Taylor, B. P., Loftness, B., Johnson, H., Schubert, P. L., Shephard, H. M., Doucette, M., … Sabeti, P. C. (2021). Evidence of transmission from fully vaccinated individuals in a large outbreak of the SARS-CoV-2 Delta variant in Provincetown, Massachusetts (p. 2021.10.20.21265137). https://doi.org/10.1101/2021.10.20.21265137

    1. Mlcochova, P., Kemp, S. A., Dhar, M. S., Papa, G., Meng, B., Ferreira, I. A. T. M., Datir, R., Collier, D. A., Albecka, A., Singh, S., Pandey, R., Brown, J., Zhou, J., Goonawardane, N., Mishra, S., Whittaker, C., Mellan, T., Marwal, R., Datta, M., … Gupta, R. K. (2021). SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion. Nature, 1–6. https://doi.org/10.1038/s41586-021-03944-y

    1. Barros-Martins, J., Hammerschmidt, S. I., Cossmann, A., Odak, I., Stankov, M. V., Morillas Ramos, G., Dopfer-Jablonka, A., Heidemann, A., Ritter, C., Friedrichsen, M., Schultze-Florey, C., Ravens, I., Willenzon, S., Bubke, A., Ristenpart, J., Janssen, A., Ssebyatika, G., Bernhardt, G., Münch, J., … Behrens, G. M. N. (2021). Immune responses against SARS-CoV-2 variants after heterologous and homologous ChAdOx1 nCoV-19/BNT162b2 vaccination. Nature Medicine, 1–5. https://doi.org/10.1038/s41591-021-01449-9

  3. Sep 2021
    1. Twohig, K. A., Nyberg, T., Zaidi, A., Thelwall, S., Sinnathamby, M. A., Aliabadi, S., Seaman, S. R., Harris, R. J., Hope, R., Lopez-Bernal, J., Gallagher, E., Charlett, A., Angelis, D. D., Presanis, A. M., Dabrera, G., Koshy, C., Ash, A., Wise, E., Moore, N., … Gunson, R. (2021). Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B.1.617.2) compared with alpha (B.1.1.7) variants of concern: A cohort study. The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(21)00475-8

    1. Kraemer, M. U. G., Hill, V., Ruis, C., Dellicour, S., Bajaj, S., McCrone, J. T., Baele, G., Parag, K. V., Battle, A. L., Gutierrez, B., Jackson, B., Colquhoun, R., O’Toole, Á., Klein, B., Vespignani, A., COVID-19 Genomics UK (COG-UK) Consortium‡, Volz, E., Faria, N. R., Aanensen, D. M., … Pybus, O. G. (2021). Spatiotemporal invasion dynamics of SARS-CoV-2 lineage B.1.1.7 emergence. Science, 373(6557), 889–895. https://doi.org/10.1126/science.abj0113

  4. Aug 2021
    1. Tim Plante, MD MHS on Twitter: “Just reported: About half of recent ICU patients with #Covid19 in #Vermont are vaccinated. Sounds like the vaccines aren’t working, right? WRONG. Vaccines are working and here’s why. But first, let’s talk a bit about unprotected sex. A thread. (Refs at the end.) 1/n https://t.co/iyQcfCDAfh” / Twitter. (n.d.). Retrieved August 27, 2021, from https://twitter.com/tbplante/status/1430222978961317896

    1. Liu, Y., Arase, N., Kishikawa, J., Hirose, M., Li, S., Tada, A., Matsuoka, S., Arakawa, A., Akamatsu, K., Ono, C., Jin, H., Kishida, K., Nakai, W., Kohyama, M., Nakagawa, A., Yamagishi, Y., Nakagami, H., Kumanogoh, A., Matsuura, Y., … Arase, H. (2021). The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines (p. 2021.08.22.457114). https://doi.org/10.1101/2021.08.22.457114

    1. Prof. Christina Pagel on Twitter: “THREAD latest on B.1.617.2 variant in England: B.1.617.2 (1st discovered in India) is now dominant in England. Here is a thread summarising latest PHE report and Sanger local data. TLDR: it is NOT good news. 1/7” / Twitter. (n.d.). Retrieved August 24, 2021, from https://twitter.com/chrischirp/status/1399333330286415876

    1. Madhi, S. A., Koen, A. L., Izu, A., Fairlie, L., Cutland, C. L., Baillie, V., Padayachee, S. D., Dheda, K., Barnabas, S. L., Bhorat, Q. E., Briner, C., Aley, P. K., Bhikha, S., Hermanus, T., Horne, E., Jose, A., Kgagudi, P., Lambe, T., Masenya, M., … Kwatra, G. (2021). Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in people living with and without HIV in South Africa: An interim analysis of a randomised, double-blind, placebo-controlled, phase 1B/2A trial. The Lancet HIV, 0(0). https://doi.org/10.1016/S2352-3018(21)00157-0

    1. Kai Kupferschmidt on Twitter: “One of the most important things I was looking for in reporting on #SARSCoV2 evolution was a way of making sense of all the virus variants, putting them in some framework. And one of the most useful things I found for that is this antigenic map. It’s worth explaining a bit: Https://t.co/miO8Kh9w9e” / Twitter. (n.d.). Retrieved August 22, 2021, from https://twitter.com/kakape/status/1428650961652916230?s=20

    1. André Picard on Twitter: “Most of those numbers are in the column, which focuses on a) the risk of the Delta variant to children under 12 and b) the 29% of Canadians who are not fully vaccinated. Brace yourself for more COVID-19 nastiness https://t.co/V0agVYvKRx” / Twitter. (n.d.). Retrieved August 13, 2021, from https://twitter.com/picardonhealth/status/1425316861176995840

    1. Craig Spencer MD MPH. (2021, August 6). Even with Delta, the likelihood of severe illness if you’re fully immunized is still a small fraction of the likelihood for the unvaccinated. In other words, nearly every COVID-19-related death right now is preventable with vaccination. [Tweet]. @Craig_A_Spencer. https://twitter.com/Craig_A_Spencer/status/1423674337089949710

    1. Justin Baragona on Twitter: “There seems to be a concerted effort today by Fox’s daytime news shows to promote the vaccines to its audience. Dr. Marc Siegel says ‘the Delta variant needs to be a wake-up call to get vaccinated.’ Anchor John Roberts then directs viewers to the government vaccine website. Https://t.co/T5b21nXCfe” / Twitter. (n.d.). Retrieved August 4, 2021, from https://twitter.com/justinbaragona/status/1417178420950220811

    1. John Burn-Murdoch. (2021, May 27). NEW: B.1617.2 is fuelling a third wave in the UK, with not only cases but also hospital admissions rising. Vaccines will make this wave different to those that have come before, but it remains a concern, and one that other countries will soon face. Thread on everything we know: Https://t.co/4825qOqgrl [Tweet]. @jburnmurdoch. https://twitter.com/jburnmurdoch/status/1397995388267810818

    1. Zeke Emanuel on Twitter: “Masks are off, theaters and indoor dining are back: Life seems to be returning to normal. But the highly transmissible Delta variant is spreading quickly, & we aren’t even halfway to a fully vaccinated population. It’s time for employer vaccine mandates. Https://t.co/34UArFfHN5” / Twitter. (n.d.). Retrieved August 1, 2021, from https://twitter.com/ZekeEmanuel/status/1418266496749428737?s=20

  5. Jul 2021
    1. Carl T. Bergstrom. (2021, May 27). An update on the B.1.617.2 lineage. I’m concerned. Not because of reduced vaccine efficacy, but simply because a further increase in transmissibility above B.1.1.7 would be quite bad news for countries where vaccination is low and for hopes of near-elimination everywhere. [Tweet]. @CT_Bergstrom. https://twitter.com/CT_Bergstrom/status/1398029743954432005

    1. Kraemer, M. U. G., Hill, V., Ruis, C., Dellicour, S., Bajaj, S., McCrone, J. T., Baele, G., Parag, K. V., Battle, A. L., Gutierrez, B., Jackson, B., Colquhoun, R., O’Toole, Á., Klein, B., Vespignani, A., Consortium‡, T. C.-19 G. U. (CoG-U., Volz, E., Faria, N. R., Aanensen, D., … Pybus, O. G. (2021). Spatiotemporal invasion dynamics of SARS-CoV-2 lineage B.1.1.7 emergence. Science. https://doi.org/10.1126/science.abj0113

  6. Jun 2021
    1. Eric Topol on Twitter: “As the Delta variant (B.1.617.2) becomes dominant throughout the world, there are 2 patterns emerging: —Countries w/ low vaccination rates are seeing both case and fatality rates increase—Countries w/ high vaccination rate: Some case increase and minimal to no fatality increase https://t.co/sSE4RlSeUJ” / Twitter. (n.d.). Retrieved June 28, 2021, from https://twitter.com/EricTopol/status/1408195243279667204

    1. Deepti Gurdasani on Twitter: “I’m still utterly stunned by yesterday’s events—Let me go over this in chronological order & why I’m shocked. - First, in the morning yesterday, we saw a ‘leaked’ report to FT which reported on @PHE_uk data that was not public at the time🧵” / Twitter. (n.d.). Retrieved June 27, 2021, from https://twitter.com/dgurdasani1/status/1396373990986375171

    1. UK is with EU. (2021, January 18). ..The reason we are in this third lockdown is because of the anti lockdowners like Lord Sumption ..We are going in circles, countries who have done well controlled the virus and now have an economic recovery ..And every life matters #GMB @devisridhar speaking truth to power https://t.co/U3BBV0uUSb [Tweet]. @ukiswitheu. https://twitter.com/ukiswitheu/status/1351089812799950850

    1. Bolze, A., Cirulli, E. T., Luo, S., White, S., Cassens, T., Jacobs, S., Nguyen, J., Ramirez, J. M., Sandoval, E., Wang, X., Wong, D., Becker, D., Laurent, M., Lu, J. T., Isaksson, M., Washington, N. L., & Lee, W. (2021). Rapid displacement of SARS-CoV-2 variant B.1.1.7 by B.1.617.2 and P.1 in the United States [Preprint]. Infectious Diseases (except HIV/AIDS). https://doi.org/10.1101/2021.06.20.21259195

    1. Parry, H. M., Tut, G., Faustini, S., Stephens, C., Saunders, P., Bentley, C., Hilyard, K., Brown, K., Amirthalingam, G., Charlton, S., Leung, S., Chiplin, E., Coombes, N. S., Bewley, K. R., Penn, E. J., Rowe, C., Otter, A., Watts, R., D’Arcangelo, S., … Moss, P. (2021). BNT162b2 Vaccination in People Over 80 Years of Age Induces Strong Humoral Immune Responses with Cross Neutralisation of P.1 Brazilian Variant. SSRN Electronic Journal. https://doi.org/10.2139/ssrn.3816840

    1. Wall, E. C., Wu, M., Harvey, R., Kelly, G., Warchal, S., Sawyer, C., Daniels, R., Hobson, P., Hatipoglu, E., Ngai, Y., Hussain, S., Nicod, J., Goldstone, R., Ambrose, K., Hindmarsh, S., Beale, R., Riddell, A., Gamblin, S., Howell, M., … Bauer, D. L. (2021). Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination. The Lancet, 0(0). https://doi.org/10.1016/S0140-6736(21)01290-3