1,276 Matching Annotations
  1. Dec 2022
  2. Nov 2022
  3. Oct 2022
    1. In the interest of reducing warranty claims (which are much more expensive than that incremental manufacturing cost) carmakers are sizing the whole unit to reliably accommodate the worst case draw (driver turns everything on at the same time, at idle).
  4. Sep 2022
    1. David Brady and colleagues have shown this to be empirically the case across29 rich democracies. The authors focused on four major risks of poverty—loweducation, single motherhood, young adults heading a household, and unem-ployment. They found that although the prevalence of these risks in the UnitedStates is actually below the average in other countries, the rate of poverty inthe United States is the highest. The reason is that “the penalties for risks inthe United States are the highest of the 29 countries. An individual with allfour risks has an extremely heightened probability of being poor in the UnitedStates.”

      How did we get to this point and how do we move away from it?

      What does David Brady's research indicate about the other countries that makes them more resilient to poverty despite these problems?

      Is it a feature of institutional racism that causes this problem?

    1. Svensk vård och skola har blivit en guldgruva för riskkapitalister. Ett av de tydligaste exemplen heter Anders Hultin. Han blev känd för en vidare krets efter att Aftonbladets ledarsida uppmärksammat att han taktlöst lagt ut en bild på ett sjuhundrakronors vin på Facebook och texten: "Because I'm worth it". Då hade han som vd för skolkoncernen John Bauer precis ansökt om konkurs. 14 500 elever förlorade sina skolor och deras lärare hade blivit arbetslösa.Men Anders Hultin gick det, som han själv konstaterade, ingen nöd på. För en billig peng kunde han köpa ut ett antal skolor ur det egna konkursboet och drev dem vidare i det nystartade bolaget Fria Läroverken.
  5. Aug 2022
    1. Gilbert, P. B., Montefiori, D. C., McDermott, A., Fong, Y., Benkeser, D. C., Deng, W., Zhou, H., Houchens, C. R., Martins, K., Jayashankar, L., Castellino, F., Flach, B., Lin, B. C., O’Connell, S., McDanal, C., Eaton, A., Sarzotti-Kelsoe, M., Lu, Y., Yu, C., … Teams, U. S. G. (USG)/CoVPN B. (2021). Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial. MedRxiv, 2021.08.09.21261290. https://doi.org/10.1101/2021.08.09.21261290

    1. Anthony Costello. (2022, February 24). The risks of cognitive symptoms lasting at least 12 MONTHS were much higher in the infected group. 4.8x higher for fatigue, 3.2x for brain fog, 5.3x for poor memory, and an incredible 51x for altered taste and smell. We need data on children, but it could easily be similar. (17) https://t.co/JC1qYyW2Xc [Tweet]. @globalhlthtwit. https://twitter.com/globalhlthtwit/status/1496957266016313348

    1. (e.g., the ability to quickly onboard new collateral types and change risk and auction parameters).

      This calls for a dynamic gov process relative to the market conditions. Gov-->clear and open in stable markets Gov-->versatile and swift in fast-paced changes

  6. Jun 2022
  7. bafybeiccxkde65wq2iwuydltwmfwv733h5btvyrzqujyrt5wcfjpg4ihf4.ipfs.dweb.link bafybeiccxkde65wq2iwuydltwmfwv733h5btvyrzqujyrt5wcfjpg4ihf4.ipfs.dweb.link
    1. Efforts to incorporate, even in a limited way, some of these issues and introduce moresevere damage functions and different assumptions on technology or distribution generatemarkedly different conclusions about the optimum trajectories.

      Including these catastrophic risks dramatically alters the conclusions and optimum trajectories.

    2. the world has been much morefocused than the IAMs on a different set of issues, the risks of catastrophic consequences.These potentially catastrophic risks are in large measure assumed away in the IAMs.

      Assumptions of catastrophic risks have not been included in the IAMs.

  8. May 2022
    1. At every step of the process we target a specific risk: the risk of not shipping on time. .... Improving your discovery process should come after regaining your ability to ship.

      You can have the best strategy in the world, but if you can't act on it, what good does it do?

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    Annotators

  9. Apr 2022
    1. Kai Kupferschmidt. (2021, December 1). @DirkBrockmann But these kinds of models do help put into context what it means when certain countries do or do not find the the variant. You can find a full explanation and a break-down of import risk in Europe by airport (and the people who did the work) here: Https://covid-19-mobility.org/reports/importrisk_omicron/ https://t.co/JXsYdmTnNP [Tweet]. @kakape. https://twitter.com/kakape/status/1466109304423993348

    1. ReconfigBehSci [@i]. (2021, November 27). @STWorg @PhilippMSchmid @CorneliaBetsch this clip got me too- for non-German speakers. She is asked whether she is ‘concerned’. Her response: Of course I’m concerned, I’m double vexed, I’m waiting for my booster vaccination, my husband died of Covid, I was in hospital, now I’m avoiding my grand children [Tweet]. Twitter. https://twitter.com/i/web/status/1464660287739596802

    1. ReconfigBehSci on Twitter: ‘@STWorg @PhilippMSchmid @CorneliaBetsch and every now and then we have to watch a clip like this to be reminded what all of this is really about. This pain and suffering is happening in one of the richest countries in the world at a time in the pandemic when we know exactly what to do to avoid it’ / Twitter. (n.d.). Retrieved 22 April 2022, from https://twitter.com/SciBeh/status/1464662622440144896

    1. Covid One Year Ago. (2021, March 12). 12 March 2020 “The public could be putting themselves more at risk from contracting coronavirus by wearing face masks.” “Jenny Harries, England’s deputy chief medical officer, said the masks could ‘actually trap the virus’ and cause the person wearing it to breathe it in” https://t.co/ar5kOOxih3 [Tweet]. @YearCovid. https://twitter.com/YearCovid/status/1370307577888698369

    1. Natalie E. Dean, PhD. (2021, May 4). The imminent FDA authorization of a vaccine for 12-15 year olds is great news, and adolescents should be able to access vaccine. But in the short term, we must also grapple with the ethics of vaccinating adolescents ahead of high-risk adults in other countries. [Tweet]. @nataliexdean. https://twitter.com/nataliexdean/status/1389381649314598914

    1. Natalie E. Dean, PhD. (2021, May 4). Another framing for this tweet: Wow, the US will soon be able to expand vaccine access to 12-15 year olds. Meanwhile, there are countries where healthcare workers treating COVID patients can’t access vaccines. What more can the US government do to support the global community? [Tweet]. @nataliexdean. https://twitter.com/nataliexdean/status/1389568668548349952

    1. ReconfigBehSci. (2021, November 18). reports of Covid “parties” and resultant deaths from Austria. This presumably is a potential reason for why policy might chose to not treat recovery as equivalent to vaccination where restrictions based on status are in place (e.g., 2G,3G in Germany and Austria) https://t.co/xH3btENi4X [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1461013914792169478

  10. Mar 2022
    1. Eric Topol. (2022, February 28). A multimodal #AI study of ~54 million blood cells from Covid patients @YaleMedicine for predicting mortality risk highlights protective T cell role (not TH17), poor outcomes of granulocytes, monocytes, and has 83% accuracy https://nature.com/articles/s41587-021-01186-x @NatureBiotech @KrishnaswamyLab https://t.co/V32Kq0Q5ez [Tweet]. @EricTopol. https://twitter.com/EricTopol/status/1498373229097799680

    1. ReconfigBehSci on Twitter: ‘@STWorg @ProfColinDavis @rpancost @chrisdc77 @syrpis this is the most in depth treatment of the impact of equalities law on pandemic policy that I’ve been able to find- it would seem to underscore that there is a legal need for impact assessments that ask (some) of these questions https://t.co/auiApVC0TW’ / Twitter. (n.d.). Retrieved 22 March 2022, from https://twitter.com/SciBeh/status/1485927221449613314

  11. Feb 2022
    1. Meaghan Kall. (2022, February 17). BA.2 risk assessment New this week is upgrading Immune Evasion—Amber 🟨 from low to moderate that BA.2 is antigentically different to BA.1 Unsurprising given the mutation profile, with BA.2 slightly more immune evasive than BA.1 on neuts studies https://t.co/n6DWtiRaNH [Tweet]. @kallmemeg. https://twitter.com/kallmemeg/status/1494100170195312646

    1. Yamasoba, D., Kimura, I., Nasser, H., Morioka, Y., Nao, N., Ito, J., Uriu, K., Tsuda, M., Zahradnik, J., Shirakawa, K., Suzuki, R., Kishimoto, M., Kosugi, Y., Kobiyama, K., Hara, T., Toyoda, M., Tanaka, Y. L., Butlertanaka, E. P., Shimizu, R., … Sato, K. (2022). Virological characteristics of SARS-CoV-2 BA.2 variant (p. 2022.02.14.480335). bioRxiv. https://doi.org/10.1101/2022.02.14.480335

    1. APPG on Coronavirus. (2022, January 18). 🗣Dr.Claire Steves continued: “Looking in the national core studies, from cohort studies across the UK we’ve looked at 10 different longitudinal studies. Our best estimates are that about 5% of middle aged people are experiencing long term.. 27/ #APPGCoronavirus #LongCovid [Tweet]. @AppgCoronavirus. https://twitter.com/AppgCoronavirus/status/1483453895061999618

    1. F. Perry Wilson, MD MSCE. (2022, February 4). If you, like me, are “skipping ahead” during the ACIP meeting re: Moderna vaccine—This slide really drives home the benefit / risk paradigm among the group at highest risk of myocarditis (men 18-35). 2 million shots = 1903 avoided hospitalizations, and 68 myocarditis cases. Https://t.co/3nzWXGXyD1 [Tweet]. @fperrywilson. https://twitter.com/fperrywilson/status/1489649379979972609

    1. Agarwal, A., Rochwerg, B., Lamontagne, F., Siemieniuk, R. A., Agoritsas, T., Askie, L., Lytvyn, L., Leo, Y.-S., Macdonald, H., Zeng, L., Amin, W., Barragan, F. A., Bausch, F. J., Burhan, E., Calfee, C. S., Cecconi, M., Chanda, D., Dat, V. Q., Sutter, A. D., … Vandvik, P. O. (2020). A living WHO guideline on drugs for covid-19. BMJ, 370, m3379. https://doi.org/10.1136/bmj.m3379

    1. Su, Y., Yuan, D., Chen, D. G., Ng, R. H., Wang, K., Choi, J., Li, S., Hong, S., Zhang, R., Xie, J., Kornilov, S. A., Scherler, K., Pavlovitch-Bedzyk, A. J., Dong, S., Lausted, C., Lee, I., Fallen, S., Dai, C. L., Baloni, P., … Heath, J. R. (2022). Multiple Early Factors Anticipate Post-Acute COVID-19 Sequelae. Cell, 0(0). https://doi.org/10.1016/j.cell.2022.01.014

    1. Krutika Kuppalli, MD FIDSA. (2022, January 14). If you had #COVID19 once you can get it again (and again). Risk of reinfection in England with #Omicron was ~5.4 fold higher compared to #Delta The relative risk were 6.36 & 5.02 for unvaxxd & vaxxd cases—Implies protection against reinfection by Omicron may be as low as 19% [Tweet]. @KrutikaKuppalli. https://twitter.com/KrutikaKuppalli/status/1482074117742288898

    1. ReconfigBehSci. (2022, January 20). @timcolbourn @OmicronData 2/n are these fair: - Getting Covid is not intrinsically sufficiently aversive that we would want to avoid catching it—Getting Covid does not give rise to additive damage to health each time—The risks associated with catching covid are constant or diminishing on reinfection [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1484076028855296008

    1. This article is for those who want to keep traveling despite restrictions due to covid. Basically giving tips on how to navigate the multiple governmental restrictions and policies including links to airline or country websites for choosing destinations. Because of this trend in travel advice in covid times, we may see attitudes towards travel shift to travel knowing the risks involved (quarantine, masks requirements, etc.) and hence see tourism rise again. Last minute covid holiday packages. What if the trend for remaining home also stayed the same for next five years and the adventure seekers become the avatars for the folks who want to stay at home.

      The crisis is changing the way how people will enjoy their international holiday, with an extra concern on testing and quarantine expenses and risk taking. That may have an impact on the tourism market, asking the airline companies to provide flexible policies /products and may witness the booming of travel insurance market.

  12. Jan 2022
    1. Routen, A., O’Mahoney, L., Ayoubkhani, D., Banerjee, A., Brightling, C., Calvert, M., Chaturvedi, N., Diamond, I., Eggo, R., Elliott, P., Evans, R. A., Haroon, S., Herret, E., O’Hara, M. E., Shafran, R., Stanborough, J., Stephenson, T., Sterne, J., Ward, H., & Khunti, K. (2022). Understanding and tracking the impact of long COVID in the United Kingdom. Nature Medicine, 28(1), 11–15. https://doi.org/10.1038/s41591-021-01591-4

    1. Deanna Behrens, MD (she/her). (2022, January 30). One U.S. child loses a parent or caregiver for every four COVID-19-associated deaths I’m not discounting mental health effects of the pandemic on children. That is real. But the risks associated with #COVID19 for children and its affects on them aren’t always obvious [Tweet]. @DeannaMarie208. https://twitter.com/DeannaMarie208/status/1487607849664581634

    1. Angel, D. M., Gao, D., DeLay, K., Lin, E. Z., Eldred, J., Arnold, W., Santiago, R., Redlich, C., Martinello, R. A., Sherman, J. D., Peccia, J., & Godri Pollitt, K. J. (2022). Development and Application of a Polydimethylsiloxane-Based Passive Air Sampler to Assess Personal Exposure to SARS-CoV-2. Environmental Science & Technology Letters. https://doi.org/10.1021/acs.estlett.1c00877

    1. Patone, M., Mei, X. W., Handunnetthi, L., Dixon, S., Zaccardi, F., Shankar-Hari, M., Watkinson, P., Khunti, K., Harnden, A., Coupland, C. A., Channon, K. M., Mills, N. L., Sheikh, A., & Hippisley-Cox, J. (2021). Risk of myocarditis following sequential COVID-19 vaccinations by age and sex (p. 2021.12.23.21268276). medRxiv. https://doi.org/10.1101/2021.12.23.21268276

    1. In a recent paper, Pierre Azoulay and co-authors concluded that Howard Hughes Medical Institute’s long-term grants to high-potential scientists made those scientists 96 percent more likely to produce breakthrough work. If this finding is borne out, it suggests that present funding mechanisms are likely to be far from optimal, in part because they do not focus enough on research autonomy and risk taking.

      Risk taking and the potential return are key pieces of progress.

      Most of our research funding apparatus isn't set up with a capitalistic structure. Would that be good or bad for accelerating progress?

    1. Prof. Gavin Yamey MD MPH. (2022, January 7). Thank you @j_g_allen for continuing to advocate for childhood vaccination & for sharing evidence on masks Yesterday, the U.S. saw a record number of COVID-19 pediatric hospital admissions, almost 1,000 Unvaxxed kids are 10 X more likely to be hospitalized than vaxxed kids 1/2 [Tweet]. @GYamey. https://twitter.com/GYamey/status/1479265484562386944

    1. Multiple factors appear to increase the risk of PGD, including depression, anxiety disorders, current substance use/abuse, multiple losses, particularly stressful circumstances surrounding the death, lack of social supports, uncertainty about the death, and the unavailability of usual mourning rituals.

      depression, anxiety disorders, current substance use/abuse, multiple losses, particularly stressful circumstances surrounding the death, lack of social supports, uncertainty about the death, the unavailability of usual mourning rituals

    1. Frenzel, S. B., Junker, N. M., Avanzi, L., Bolatov, A., Haslam, S. A., Häusser, J. A., Kark, R., Meyer, I., Mojzisch, A., Monzani, L., Reicher, S., Samekin, A., Schury, V. A., Steffens, N. K., Sultanova, L., Van Dijk, D., van Zyl, L. E., & Van Dick, R. (2022). A trouble shared is a trouble halved: The role of family identification and identification with humankind in well-being during the COVID-19 pandemic. British Journal of Social Psychology, 61(1), 55–82. https://doi.org/10.1111/bjso.12470

    1. ReconfigBehSci. (2022, January 4). “Importantly, higher study quality was associated with lower prevalence of all symptoms, except loss of smell & cognitive symptoms” ....as someone who studies cognition I didn’t find that as reassuring as possibly intended... [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1478341731707981829

    1. Riepenhausen, A., Veer, I., Wackerhagen, C., Reppmann, Z. C., Köber, G., Ayuso-Mateos, J.-L., Bögemann, S., Corrao, G., Felez-Nobrega, M., Abad, J. M. H., Hermans, E., Leeuwen, J. van, Lieb, P. D. K., Lorant, V., Mary-Krause, M., Mediavilla, R., Melchior, M., Mittendorfer-Rutz, E., Compagnoni, M. M., … Walter, H. (2021). Coping with COVID: Risk and Resilience Factors for Mental Health in a German Representative Panel Study. PsyArXiv. https://doi.org/10.31234/osf.io/fjqpb

  13. Dec 2021
    1. Deepti Gurdasani. (2021, December 23). Some brief thoughts on the concerning relativism I’ve seen creeping into media, and scientific rhetoric over the past 20 months or so—The idea that things are ok because they’re better relative to a point where things got really really bad. 🧵 [Tweet]. @dgurdasani1. https://twitter.com/dgurdasani1/status/1474042179110772736

    1. Patone, M., Mei, X. W., Handunnetthi, L., Dixon, S., Zaccardi, F., Shankar-Hari, M., Watkinson, P., Khunti, K., Harnden, A., Coupland, C. A. C., Channon, K. M., Mills, N. L., Sheikh, A., & Hippisley-Cox, J. (2021). Risks of myocarditis, pericarditis, and cardiac arrhythmias associated with COVID-19 vaccination or SARS-CoV-2 infection. Nature Medicine, 1–13. https://doi.org/10.1038/s41591-021-01630-0