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ReconfigBehSci. (2020, November 9). RT @peterbachmd: Relevant today: Ever sharp @nataliexdean on Vaccine Effectiveness vs Efficacy from many moons ago (i.e. About a month). Sh… [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1325889181097267200
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As vaccines start rolling out, here’s what our research says about communication and coronavirus. (n.d.). Reuters Institute for the Study of Journalism. Retrieved 13 January 2021, from https://reutersinstitute.politics.ox.ac.uk/risj-review/vaccines-start-rolling-out-heres-what-our-research-says-about-communication-and
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phastar.com phastar.com
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US pharmacist who tried to ruin Covid vaccine doses is a conspiracy theorist, police say. (2021, January 5). The Guardian. http://www.theguardian.com/us-news/2021/jan/04/wisconsin-pharmacist-covid-19-vaccine-doses-steven-brandenburg
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US pharmacist who tried to ruin Covid vaccine doses is a conspiracy theorist, police say. (2021, January 5). The Guardian. http://www.theguardian.com/us-news/2021/jan/04/wisconsin-pharmacist-covid-19-vaccine-doses-steven-brandenburg
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Marsh, S. (2020, December 4). Vaccine expert tells ministers: ‘Stop boasting and get public onboard’. The Guardian. https://www.theguardian.com/politics/2020/dec/04/advice-to-uk-ministers-stop-vaccine-boasting-and-get-public-onboard
Tags
- public
- is:news
- vaccine
- misinformation
- VCP
- distribution
- COVID-19
- minister
- government
- UK
- lang:en
- long term plan
- hesitancy
- information
Annotators
URL
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www.theatlantic.com www.theatlantic.com
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Zhang, S. (2020, May 24). We Don’t Even Have a COVID-19 Vaccine, and Yet the Conspiracies Are Here. The Atlantic. https://www.theatlantic.com/science/archive/2020/05/covid-19-vaccine-skeptics-conspiracies/611998/
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Zhang, S. (2020, September 28). Vaccine Chaos Is Looming. The Atlantic. https://www.theatlantic.com/health/archive/2020/09/covid-19-most-complicated-vaccine-campaign-ever/616521/
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Zhang, S. (2020, November 10). The Lame-Duck Vaccine. The Atlantic. https://www.theatlantic.com/health/archive/2020/11/bidens-vaccine-reset/617059/
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Zhang, S. (2020, December 1). The Long Haul of Vaccine Results Is Just Beginning. The Atlantic. https://www.theatlantic.com/health/archive/2020/12/vaccine-trials-can-still-surprise-us/617247/
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www.theatlantic.com www.theatlantic.com
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Zhang, S. (2020, November 18). The End of the Pandemic Is Now in Sight. The Atlantic. https://www.theatlantic.com/health/archive/2020/11/vaccines-end-covid-19-pandemic-sight/617141/
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- Dec 2020
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mRNA-1273 vaccine candidate, manufactured by Moderna, encodes the S-2P antigen, consisting of the SARS-CoV-2 glycoprotein with a transmembrane anchor and an intact S1–S2 cleavage site. S-2P is stabilized in its prefusion conformation by two consecutive proline substitutions at amino acid positions 986 and 987, at the top of the central helix in the S2 subunit
Tags
Annotators
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www.theguardian.com www.theguardian.com
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Sridhar, D. (2020, November 16). It’s not just the vaccine. There are many causes for hope in the fight against Covid | Devi Sridhar. The Guardian. https://www.theguardian.com/commentisfree/2020/nov/16/vaccine-hope-fight-covid-tests-treatments
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www.nature.com www.nature.com
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Cyranoski, D. (2020). Arab nations first to approve Chinese COVID vaccine—Despite lack of public data. Nature, 588(7839), 548–548. https://doi.org/10.1038/d41586-020-03563-z
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www.nature.com www.nature.com
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Ledford, H., Cyranoski, D., & Noorden, R. V. (2020). The UK has approved a COVID vaccine—Here’s what scientists now want to know. Nature, 588(7837), 205–206. https://doi.org/10.1038/d41586-020-03441-8
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Katy Milkman on how to nudge people to accept a covid-19 vaccine. (2020, November 30). The Economist. https://www.economist.com/by-invitation/2020/11/30/katy-milkman-on-how-to-nudge-people-to-accept-a-covid-19-vaccine
Tags
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www.theguardian.com www.theguardian.com
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Grover, N. (2020, December 7). WHO looks at giving Covid-19 to healthy people to speed up vaccine trials. The Guardian. https://www.theguardian.com/world/2020/dec/07/who-looks-at-giving-covid-to-healthy-people-to-speed-up-vaccine-trials
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www.biorxiv.org www.biorxiv.org
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We report the preclinical development of BNT162b2, a lipid-nanoparticle (LNP) formulated N1-methyl-pseudouridine (m1Ψ) nucleoside-modified mRNA (modRNA) vaccine candidate that encodes P2 S with a native furin cleavage site resulting in the S1 and S2 cleavage fragments
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To generate the template for RNA synthesis, a DNA fragment encoding the SARS-CoV-2 P2 279 S protein (based on GenBank: MN908947), including the amino acid exchanges K986P and 280 V987P, was cloned into a starting plasmid vector with backbone sequence elements for 281 improved RNA stability and translational efficiency19,34
BNT162b2
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How We Can Stop the Spread of Coronavirus by Christmas. (n.d.). Time. Retrieved December 17, 2020, from https://time.com/5912705/covid-19-stop-spread-christmas/
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ted.europa.eu ted.europa.eu
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The MHRA urgently seeks an Artificial Intelligence (AI) software tool to process the expected high volume of Covid-19 vaccine Adverse Drug Reaction (ADRs) and ensure that no details from the ADRs’ reaction text are missed.
Is this expectation higher than for other coronavirus vaccines? MHRA: Medicines & Healthcare products Regulatory Agency
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www.nature.com www.nature.com
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Ledford, H. (2020). Oxford COVID-vaccine paper highlights lingering unknowns about results. Nature. https://doi.org/10.1038/d41586-020-03504-w
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www.thelancet.com www.thelancet.com
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Voysey, M., Clemens, S. A. C., Madhi, S. A., Weckx, L. Y., Folegatti, P. M., Aley, P. K., Angus, B., Baillie, V. L., Barnabas, S. L., Bhorat, Q. E., Bibi, S., Briner, C., Cicconi, P., Collins, A. M., Colin-Jones, R., Cutland, C. L., Darton, T. C., Dheda, K., Duncan, C. J. A., … Zuidewind, P. (2020). Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: An interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. The Lancet, 0(0). https://doi.org/10.1016/S0140-6736(20)32661-1
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Karl Friston and Anthony Costello: What we have learned from the second covid-19 surge? (2020, December 8). The BMJ. https://blogs.bmj.com/bmj/2020/12/08/karl-friston-and-anthony-costello-what-we-have-learned-from-the-second-covid-19-surge/
Tags
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www.theatlantic.com www.theatlantic.com
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Serhan, Y. (2020, December 8). Vaccine Nationalism Is Doomed to Fail. The Atlantic. https://www.theatlantic.com/international/archive/2020/12/vaccine-nationalism-doomed-fail/617323/
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twitter.com twitter.com
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A Marm Kilpatrick. (2020, December 8). FDA Pfizer/BioNTech vaccine efficacy results are great, but aren’t nearly as great as presented for severe infections. Everyone has seen fig below on cases in vaccine (blue) & placebo (red) over time. Thread. Https://t.co/vlZyZgJ7hr https://t.co/9ZWeWCko1x [Tweet]. @DiseaseEcology. https://twitter.com/DiseaseEcology/status/1336446195284070400
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Coronavirus (COVID-19) vaccine. (2020, November 26). Nhs.Uk. https://www.nhs.uk/conditions/coronavirus-covid-19/coronavirus-vaccination/coronavirus-vaccine/
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NHS told not to give Covid vaccine to those with history of allergic reactions. (2020, December 9). The Guardian. http://www.theguardian.com/world/2020/dec/09/pfizer-covid-vaccine-nhs-extreme-allergy-sufferers-regulators-reaction
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In a webinar hosted by MIT Sloan School of Management professor Andrew Lo on April 1, Bancel said that Moderna is already manufacturing mRNA for vaccines in its potential Phase II study, which could begin enrolling hundreds of people this spring, as well as its potential Phase III study, which could enroll thousands of people as early as late summer or early fall. In a US Securities and Exchange Commission filing the week before, Bancel also indicated that Moderna may request special permission to give people like doctors and nurses access to its vaccine this fall, before a formal approval. It’s an audacious plan for a company—and technology—that has yet to put a drug on the market.
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investors.modernatx.com investors.modernatx.com
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Moderna’s COVID-19 Vaccine Candidate Meets its Primary Efficacy Endpoint in the First Interim Analysis of the Phase 3 COVE Study | Moderna, Inc. (n.d.). Retrieved 1 December 2020, from https://investors.modernatx.com/news-releases/news-release-details/modernas-covid-19-vaccine-candidate-meets-its-primary-efficacy/
Tags
- biotechnology
- vaccine efficacy
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- Nov 2020
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www.sciencemag.org www.sciencemag.org
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CohenNov. 16, J., 2020, & Am, 7:00. (2020, November 16). ‘Just beautiful’: Another COVID-19 vaccine, from newcomer Moderna, succeeds in large-scale trial. Science | AAAS. https://www.sciencemag.org/news/2020/11/just-beautiful-another-covid-19-vaccine-newcomer-moderna-succeeds-large-scale-trial
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- Moderna
- optimism
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- Oct 2020
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www.youtube.com www.youtube.com
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COVID-19: The 9/11 Moment for Global Public Health? Dr. Richard Horton and Clive Cookson. (2020, September 1). https://www.youtube.com/watch?v=97iJIwBQ5qE&feature=youtu.be
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www.theguardian.com www.theguardian.com
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Global Covid report: Young and healthy may not get vaccine until 2022, WHO says. (2020, October 15). The Guardian. http://www.theguardian.com/world/2020/oct/15/global-covid-report-young-and-healthy-may-not-get-vaccine-until-2022-who-says
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www.npr.org www.npr.org
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Aubrey, A. (2020). Will Kids Get A COVID-19 Vaccine? Pfizer To Expand Trial To Ages 12 And Up. NPR. https://www.npr.org/sections/health-shots/2020/10/13/923248377/will-kids-get-a-covid-19-vaccine-pfizer-to-expand-trial-to-ages-12-and-up?t=1602805163253
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www.scientificamerican.com www.scientificamerican.com
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Nouri, A. B., Ali. (n.d.). COVID Misinformation Is Killing People. Scientific American. Retrieved October 12, 2020, from https://www.scientificamerican.com/article/covid-misinformation-is-killing-people1/
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NW, 1615 L. St, Suite 800Washington, & Inquiries, D. 20036USA202-419-4300 | M.-857-8562 | F.-419-4372 | M. (2020, September 17). U.S. Public Now Divided Over Whether To Get COVID-19 Vaccine. Pew Research Center Science & Society. https://www.pewresearch.org/science/2020/09/17/u-s-public-now-divided-over-whether-to-get-covid-19-vaccine/
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www.thelancet.com www.thelancet.com
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Horton, R. (2020). Offline:Reasons for hope. Lancet, 396
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www.nature.com www.nature.com
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Nkengasong, J. N., Ndembi, N., Tshangela, A., & Raji, T. (2020). COVID-19 vaccines: How to ensure Africa has access. Nature, 586(7828), 197–199. https://doi.org/10.1038/d41586-020-02774-8
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www.nature.com www.nature.com
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Bingham, K. (2020). Plan now to speed vaccine supply for future pandemics. Nature, 586(7828), 171–171. https://doi.org/10.1038/d41586-020-02798-0
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- Sep 2020
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www.scientificamerican.com www.scientificamerican.com
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Haseltine, W. A. (n.d.). Lessons from AIDS for the COVID-19 Pandemic. Scientific American. https://doi.org/10.1038/scientificamerican1020-35
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twitter.com twitter.comTwitter2
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Natalie E. Dean en Twitter: “VACCINE EFFICACY 101: A biostatistician's primer. Ten tweets to cover:- How is vaccine efficacy calculated?- Distinguishing between infection, disease, & severe disease.- Measuring reduced infectiousness.- Vaccine efficacy vs. effectiveness!n” / Twitter. (n.d.). Twitter. Retrieved September 30, 2020, from https://twitter.com/nataliexdean/status/1310613702476017666
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Stephen Griffin on Twitter. (n.d.). Twitter. Retrieved September 2, 2020, from https://twitter.com/SGriffin_Lab/status/1300572439374630917
Tags
- case decrease
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www.nihr.ac.uk www.nihr.ac.uk
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Over 250,000 volunteers now registered for new COVID-19 vaccine trials as recruitment begins for Novavax study. (n.d.). Retrieved September 28, 2020, from https://www.nihr.ac.uk/news/over-250000-volunteers-now-registered-for-new-covid-19-vaccine-trials-as-recruitment-begins-for-novavax-study/25731
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- Novavax
- UK
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URL
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twitter.com twitter.com
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Pausal Živference on Twitter. (n.d.). Twitter. Retrieved September 26, 2020, from https://twitter.com/PausalZ/status/1309208611265093632
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www.scotsman.com www.scotsman.com
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Beware comforting lies about a “herd immunity” Covid-19 strategy. Here’s why it’s dangerous – Professor Devi Sridhar. (n.d.). Retrieved September 25, 2020, from https://www.scotsman.com/news/opinion/columnists/covid-19-herd-immunity-strategy-flawed-until-we-have-coronavirus-vaccine-professor-devi-sridhar-2981017
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www.nature.com www.nature.com
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Leask, Julie. ‘Vaccines — Lessons from Three Centuries of Protest’. Nature 585, no. 7826 (21 September 2020): 499–501. https://doi.org/10.1038/d41586-020-02671-0.
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news.northeastern.edu news.northeastern.edu
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If rich countries monopolize COVID-19 vaccines, it could cause twice as many deaths as distributing them equally. (n.d.). Retrieved September 17, 2020, from https://news.northeastern.edu/2020/09/14/if-rich-countries-monopolize-covid-19-vaccines-it-could-cause-twice-as-many-deaths-as-distributing-them-equally/
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Duquette, N. (2020). Heard immunity: Effective persuasion for a future COVID-19 vaccine. https://doi.org/10.31235/osf.io/jwvsp
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magazine, D. C., Smriti Mallapaty,Nature. (n.d.). Coronavirus Vaccine U.K. Trial Restarts, But Scientists Question Lack of Transparency. Scientific American. Retrieved September 16, 2020, from https://www.scientificamerican.com/article/coronavirus-vaccine-u-k-trial-restarts-but-scientists-question-lack-of-transparency/
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Public trust in vaccines rises in most of Europe, study says. (2020). Financial Times. Retrieved September 16, 2020, from https://www.ft.com/content/fd3264ea-dc97-489e-969f-a933288babbe
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Lewis, T. (n.d.). Nine COVID-19 Myths That Just Won’t Go Away. Scientific American. Retrieved September 11, 2020, from https://www.scientificamerican.com/article/nine-covid-19-myths-that-just-wont-go-away/
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Diseases, T. L. I. (2020). Curing COVID-19. The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(20)30706-4
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Emanuel, E. J., & Offit, P. A. (2020, June 8). Opinion | Could Trump Turn a Vaccine Into a Campaign Stunt? The New York Times. https://www.nytimes.com/2020/06/08/opinion/trump-coronavirus-vaccine.html
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News, A. B. C. (n.d.). Getting COVID-19 and the flu at the same time: What are the risks? ABC News. Retrieved September 2, 2020, from https://abcnews.go.com/Health/covid-19-flu-time-risks/story?id=72520950
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editor, S. B. H. (2020, August 30). Covid vaccine rush could make pandemic worse, say scientists. The Guardian. https://www.theguardian.com/society/2020/aug/30/covid-vaccine-rush-could-make-pandemic-worse-say-scientists
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Hurst, D., & Murphy, K. (2020, June 22). Trump’s misleading information enables China to sow discord among allies, research finds. The Guardian. https://www.theguardian.com/australia-news/2020/jun/23/trumps-misleading-information-enables-china-to-sow-discord-among-allies-research-finds
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Senior, J. (2020, July 21). Opinion | I Spoke With Anthony Fauci. He Says His Inbox Isn’t Pretty. The New York Times. https://www.nytimes.com/2020/07/21/opinion/anthony-fauci-coronavirus.html
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Hoffman, J. (2020, August 16). Fearing a ‘Twindemic,’ Health Experts Push Urgently for Flu Shots. The New York Times. https://www.nytimes.com/2020/08/16/health/coronavirus-flu-vaccine-twindemic.html
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Heywood, A. E., & Macintyre, C. R. (2020). Elimination of COVID-19: What would it look like and is it possible? The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(20)30633-2
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Felipe, L. S., Vercruysse, T., Sharma, S., Ma, J., Lemmens, V., Looveren, D. van, Javarappa, M. P. A., Boudewijns, R., Malengier-Devlies, B., Kaptein, S. F., Liesenborghs, L., Keyzer, C. D., Bervoets, L., Rasulova, M., Seldeslachts, L., Jansen, S., Yakass, M. B., Quaye, O., Li, L.-H., … Dallmeier, K. (2020). A single-dose live-attenuated YF17D-vectored SARS-CoV2 vaccine candidate. BioRxiv, 2020.07.08.193045. https://doi.org/10.1101/2020.07.08.193045
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LeslieMay. 14, M., 2020, & Pm, 9:00. (2020, May 14). T cells found in COVID-19 patients ‘bode well’ for long-term immunity. Science | AAAS. https://www.sciencemag.org/news/2020/05/t-cells-found-covid-19-patients-bode-well-long-term-immunity
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Zhu, F.-C., Guan, X.-H., Li, Y.-H., Huang, J.-Y., Jiang, T., Hou, L.-H., Li, J.-X., Yang, B.-F., Wang, L., Wang, W.-J., Wu, S.-P., Wang, Z., Wu, X.-H., Xu, J.-J., Zhang, Z., Jia, S.-Y., Wang, B.-S., Hu, Y., Liu, J.-J., … Chen, W. (2020). Immunogenicity and safety of a recombinant adenovirus type-5-vectored COVID-19 vaccine in healthy adults aged 18 years or older: A randomised, double-blind, placebo-controlled, phase 2 trial. The Lancet, 0(0). https://doi.org/10.1016/S0140-6736(20)31605-6
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Corbett, K. S., Edwards, D. K., Leist, S. R., Abiona, O. M., Boyoglu-Barnum, S., Gillespie, R. A., Himansu, S., Schäfer, A., Ziwawo, C. T., DiPiazza, A. T., Dinnon, K. H., Elbashir, S. M., Shaw, C. A., Woods, A., Fritch, E. J., Martinez, D. R., Bock, K. W., Minai, M., Nagata, B. M., … Graham, B. S. (2020). SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness. Nature, 1–8. https://doi.org/10.1038/s41586-020-2622-0
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Walls, A. C., Fiala, B., Schäfer, A., Wrenn, S., Pham, M. N., Murphy, M., Tse, L. V., Shehata, L., O’Connor, M. A., Chen, C., Navarro, M. J., Miranda, M. C., Pettie, D., Ravichandran, R., Kraft, J. C., Ogohara, C., Palser, A., Chalk, S., Lee, E.-C., … King, N. P. (2020). Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2. BioRxiv, 2020.08.11.247395. https://doi.org/10.1101/2020.08.11.247395
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Daas, Chantal den, Gill Hubbard, Marie Johnston, and Diane Dixon. ‘Protocol CHARIS Study’. Preprint. PsyArXiv, 19 August 2020. https://doi.org/10.31234/osf.io/jnxcu.
Tags
- physical distancing
- general health
- face coverings
- is:preprint
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- COVID-19
- lang:en
- mental health
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- protocol CHARIS
- population health
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- variations in adherence
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- Scotland
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- CHARIS
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Annotators
URL
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www.bbc.co.uk www.bbc.co.uk
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‘Missing School Is “Worse than Virus for Children”’. BBC News, 23 August 2020, sec. UK. https://www.bbc.com/news/uk-53875410.
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www.biorxiv.org www.biorxiv.org
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Sun, W., McCroskery, S., Liu, W.-C., Leist, S. R., Liu, Y., Albrecht, R. A., Slamanig, S., Oliva, J., Amanat, F., Schäfer, A., Dinnon, K. H., Innis, B. L., García-Sastre, A., Krammer, F., Baric, R. S., & Palese, P. (2020). A Newcastle disease virus (NDV) expressing membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine. BioRxiv, 2020.07.30.229120. https://doi.org/10.1101/2020.07.30.229120
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Bangaru, S., Ozorowski, G., Turner, H. L., Antanasijevic, A., Huang, D., Wang, X., Torres, J. L., Diedrich, J. K., Tian, J.-H., Portnoff, A. D., Patel, N., Massare, M. J., Yates, J. R., Nemazee, D., Paulson, J. C., Glenn, G., Smith, G., & Ward, A. B. (2020). Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate. BioRxiv, 2020.08.06.234674. https://doi.org/10.1101/2020.08.06.234674
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www.nature.com www.nature.com
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Ledford, H. (2020). What the immune response to COVID-19 says about the prospects for a vaccine. Nature. https://doi.org/10.1038/d41586-020-02400-7
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www.newscientist.com www.newscientist.com
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Marshall, M. (n.d.). Everything you need to know about Russia’s coronavirus vaccine claims. New Scientist. Retrieved August 18, 2020, from https://www.newscientist.com/article/2251722-everything-you-need-to-know-about-russias-coronavirus-vaccine-claims/
Tags
- transparency
- is:news
- vaccine
- efficacy
- development
- immunology
- COVID-19
- safety
- concern
- bad science
- public health
- Russia
- lang:en
- spike protein
- strategy
Annotators
URL
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www.nber.org www.nber.org
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Lo, A. W., Siah, K. W., & Wong, C. H. (2020). Estimating Probabilities of Success of Vaccine and Other Anti-Infective Therapeutic Development Programs (Working Paper No. 27176; Working Paper Series). National Bureau of Economic Research. https://doi.org/10.3386/w27176
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CNN, A. V., Holly Yan and Christina Maxouris. (n.d.). FDA won’t ‘cut corners’ to approve a Covid-19 vaccine, commissioner says. CNN. Retrieved 12 August 2020, from https://www.cnn.com/2020/08/10/health/us-coronavirus-monday/index.html
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CNN, C. M. (n.d.). Previous vaccines and masks may hold down Covid-19, some researchers say. CNN. Retrieved 12 August 2020, from https://www.cnn.com/2020/08/11/health/us-coronavirus-tuesday/index.html
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www.theatlantic.com www.theatlantic.com
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Yong, Ed. ‘Immunology Is Where Intuition Goes to Die’. The Atlantic, 5 August 2020. https://www.theatlantic.com/health/archive/2020/08/covid-19-immunity-is-the-pandemics-central-mystery/614956/.
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www.nber.org www.nber.org
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Hong, H., Wang, N., & Yang, J. (2020). Implications of Stochastic Transmission Rates for Managing Pandemic Risks (Working Paper No. 27218; Working Paper Series). National Bureau of Economic Research. https://doi.org/10.3386/w27218
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www.theatlantic.com www.theatlantic.com
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A Vaccine Reality Check. (n.d.). MSN. Retrieved August 9, 2020, from https://www.msn.com/en-us/news/us/a-vaccine-reality-check/ar-BB178Yaf
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Acemoglu, D., Chernozhukov, V., Werning, I., & Whinston, M. D. (2020). Optimal Targeted Lockdowns in a Multi-Group SIR Model (Working Paper No. 27102; Working Paper Series). National Bureau of Economic Research. https://doi.org/10.3386/w27102
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www.cnn.com www.cnn.com
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CNN, J. G., Naomi Thomas, Dana Vigue and Jacqueline Howard. (n.d.). Oxford’s Covid-19 vaccine appears safe and induces immune response, early results suggest. CNN. Retrieved August 2, 2020, from https://www.cnn.com/2020/07/20/health/oxford-covid-19-vaccine-results-cansino-pfizer-study/index.html
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- Jul 2020
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DNA vaccine for SARS-CoV-2 inflammations.
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www.bloomberg.com www.bloomberg.com
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The World’s Supply Chain Isn’t Ready for a Covid-19 Vaccine. (2020, July 25). Bloomberg.Com. https://www.bloomberg.com/news/articles/2020-07-25/the-supply-chain-to-save-the-world-is-unprepared-for-a-vaccine
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Younes, G. A., Ayoubi, C., Ballester, O., Cristelli, G., de Rassenfosse, G., Foray, D., Gaule, P., Pellegrino, G., van den Heuvel, M., Webster, B., & Zhou, L. (2020). COVID-19_Insights from Innovation Economists [Preprint]. SocArXiv. https://doi.org/10.31235/osf.io/b5zae
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Younes, G. A., Ayoubi, C., Ballester, O., Cristelli, G., de Rassenfosse, G., Foray, D., Gaule, P., van den Heuvel, M., Webster, B., & Zhou, L. (2020). COVID-19: Insights from Innovation Economists (with French executive summary) [Preprint]. SocArXiv. https://doi.org/10.31235/osf.io/65pgr
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psyarxiv.com psyarxiv.com
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Thorneloe, R., Wilcockson, H. E., PhD, Lamb, M., Jordan, C. H., & Arden, M. (2020, July 20). Willingness to receive a COVID-19 vaccine among adults at high-risk of COVID-19: a UK-wide survey. https://doi.org/10.31234/osf.io/fs9wk
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Sehgal, D. (2020). Analysis of Vaccines to tackle COVID-19 with Patent Review [Preprint]. SocArXiv. https://doi.org/10.31235/osf.io/q96wj
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arxiv.org arxiv.org
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Bizzarri, M., Panebianco, F., & Pin, P. (2020). Is segregating anti-vaxxers a good idea? ArXiv:2007.08523 [Physics, q-Bio, q-Fin]. http://arxiv.org/abs/2007.08523
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www.statnews.com www.statnews.com
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Herper, M. (2020, July 1). Covid-19 vaccine from Pfizer and BioNTech shows positive results. CNBC. https://www.cnbc.com/2020/07/01/coronavirus-vaccine-from-pfizer-and-biontech-shows-positive-results-report-says.html
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www.medrxiv.org www.medrxiv.org
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Mulligan, M. J., Lyke, K. E., Kitchin, N., Absalon, J., Gurtman, A., Lockhart, S. P., Neuzil, K., Raabe, V., Bailey, R., Swanson, K. A., Li, P., Koury, K., Kalina, W., Cooper, D., Fonter-Garfias, C., Shi, P.-Y., Tuereci, O., Tompkins, K. R., Walsh, E. E., … Jansen, K. U. (2020). Phase 1/2 Study to Describe the Safety and Immunogenicity of a COVID-19 RNA Vaccine Candidate (BNT162b1) in Adults 18 to 55 Years of Age: Interim Report. MedRxiv, 2020.06.30.20142570. https://doi.org/10.1101/2020.06.30.20142570
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www.nationalgeographic.com www.nationalgeographic.com
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A COVID-19 vaccine has passed its first human trial. But is it the frontrunner? (2020, May 29). Science. https://www.nationalgeographic.com/science/2020/05/coronavirus-vaccine-passes-first-human-trial-but-is-it-frontrunner-cvd/
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www.wired.com www.wired.com
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Larry Brilliant on How Well We Are Fighting Covid-19. (n.d.). Wired. Retrieved July 18, 2020, from https://www.wired.com/story/larry-brilliant-on-how-well-are-we-fighting-covid-19/
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www.thelancet.com www.thelancet.com
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Ivers, Louise C., and Daniel J. Weitzner. ‘Can Digital Contact Tracing Make up for Lost Time?’ The Lancet Public Health 0, no. 0 (16 July 2020). https://doi.org/10.1016/S2468-2667(20)30160-2.
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Richards, A. D. (2020). Ethical Guidelines for Deliberately Infecting Volunteers with COVID-19 [Preprint]. SocArXiv. https://doi.org/10.31235/osf.io/jb7gq
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www.nature.com www.nature.com
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Gewin, Virginia. ‘Remote Controller’. Nature 583, no. 7816 (13 July 2020): 484–484. https://doi.org/10.1038/d41586-020-02073-2.
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osf.io osf.io
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Machado, D. F. T., de Siqueira, A. F., & Gitahy, L. (2020). Natural stings: Alternative health services selling distrust about vaccines on YouTube [Preprint]. SocArXiv. https://doi.org/10.31235/osf.io/vtf5r
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www.biorxiv.org www.biorxiv.org
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Corbett, K. S., Edwards, D., Leist, S. R., Abiona, O. M., Boyoglu-Barnum, S., Gillespie, R. A., Himansu, S., Schäfer, A., Ziwawo, C. T., DiPiazza, A. T., Dinnon, K. H., Elbashir, S. M., Shaw, C. A., Woods, A., Fritch, E. J., Martinez, D. R., Bock, K. W., Minai, M., Nagata, B. M., … Graham, B. S. (2020). SARS-CoV-2 mRNA Vaccine Development Enabled by Prototype Pathogen Preparedness. BioRxiv, 2020.06.11.145920. https://doi.org/10.1101/2020.06.11.145920
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- Jun 2020
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psyarxiv.com psyarxiv.com
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Czarnek, G., Szwed, P., & Kossowska, M. (2020). Trust and attitudes toward vaccination: Study report. https://doi.org/10.31234/osf.io/dpa35
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Czarnek, G., Szwed, P., & Kossowska, M. (2020). Political ideology and attitudes toward vaccination: Study report. https://doi.org/10.31234/osf.io/uwehk
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jbloomlab.github.io jbloomlab.github.io
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Interactive Heat Map - SARS-CoV-2 - Bloom Lab
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www.biorxiv.org www.biorxiv.org
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Starr, T. N., Greaney, A. J., Hilton, S. K., Crawford, K. H., Navarro, M. J., Bowen, J. E., Tortorici, M. A., Walls, A. C., Veesler, D., & Bloom, J. D. (2020). Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding [Preprint]. Microbiology. https://doi.org/10.1101/2020.06.17.157982
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twitter.com twitter.com
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Bloom Lab. (2020, June 18). "We've experimentally measured how all amino-acid mutations to the #SARSCoV2 spike RBD affect ACE2 binding and expression of folded protein in a deep mutational scanning study led by @tylernstarr & Allie Greaney:https://biorxiv.org/content/10.1101/2020.06.17.157982v1 Why is this important? (1/n)" Twitter. https://twitter.com/jbloom_lab/status/1273468539484213248
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psyarxiv.com psyarxiv.com
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Muungo, L. (2020). Effects of pneumococcal vaccine in patients with chronic respiratory disease. https://doi.org/10.31234/osf.io/gwqvx
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twitter.com twitter.com
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Bergstrom, C. T. (2020, June 14). "1. Another day, another blog post of #COVID19 misinformation making the rounds." Twitter. https://twitter.com/CT_Bergstrom/status/1272007583222513664
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pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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Bertoncello, C., Ferro, A., Fonzo, M., Zanovello, S., Napoletano, G., Russo, F., Baldo, V., & Cocchio, S. (2020). Socioeconomic Determinants in Vaccine Hesitancy and Vaccine Refusal in Italy. Vaccines, 8(2). https://doi.org/10.3390/vaccines8020276
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prime.economictimes.indiatimes.com prime.economictimes.indiatimes.com
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. According to published reports, the vaccine being developed uses a replication-deficient adenovirus (a harmless virus) to deliver a SARS-CoV-2 protein to induce a protective immune response. Coded as ChAdOx1, the same vaccine has been used against several other pathogens, including one for the Mers virus.
Still nothing in sight!
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Kang cited how the BCG vaccine underwent as many as 200 sub-cultures before it was considered attenuated (weakened) enough for human use. Another leading virologist tells ET Prime that Moderna is in an uncharted territory and no vaccine using that technology has reached the licensing stage.
Requires significant attenuation before you actually see results.
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Known as messenger RNA, Moderna’s vaccine essentially aims to induce an immune response by sending instruction signals for a spike protein located on the surface of the virus. These immune cells are then expected to develop antibodies against the virus whenever a person contracts the coronavirus. Although promising, this pathway has not been successful or used to develop vaccines before.
Novel form of vaccine but not entirely worth it.
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Moderna had earlier announced that it would start its pivotal phase III studies in July, to be followed by a biologic-licence application (BLA) with the USFDA. While apprehensions have been raised over that timeline, senior researchers like Fauci who had backed Moderna’s vaccine have not made any observations on the quality of data shared.
Very bad quality of data
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He passionately explains how his team developed a reverse-genetics system against a poultry virus called avian paramyxovirus. In simple terms, this is a method of recovering a virus, manipulating its genome, and using it as a vector to induce an immune response.
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A few days ago, the US launched a public-private partnership under Operation Warp Speed that hand-picked five companies that can develop and make vaccines, diagnostics, and therapeutics on an accelerated basis.
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Hundreds of chemistry-based and biological drugs – new and existing – are being tested everyday across continents to rein in the coronavirus, but so far only one has shown partial activity.
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www.economist.com www.economist.com
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The quest for a vaccine could restore faith in big pharma. (n.d.). The Economist. Retrieved June 8, 2020, from https://www.economist.com/business/2020/06/04/the-quest-for-a-vaccine-could-restore-faith-in-big-pharma
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www.biorxiv.org www.biorxiv.org
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Robbiani, D. F., Gaebler, C., Muecksch, F., Lorenzi, J. C. C., Wang, Z., Cho, A., Agudelo, M., Barnes, C. O., Gazumyan, A., Finkin, S., Hagglof, T., Oliveira, T. Y., Viant, C., Hurley, A., Hoffmann, H.-H., Millard, K. G., Kost, R. G., Cipolla, M., Gordon, K., … Nussenzweig, M. C. (2020). Convergent Antibody Responses to SARS-CoV-2 Infection in Convalescent Individuals [Preprint]. Immunology. https://doi.org/10.1101/2020.05.13.092619
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twitter.com twitter.com
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Crotty, S. (2020, May 14). "Our new paper rapidly studied T cell + antibody immune responses in average COVID-19 cases. This is good news in multiple ways, including coronavirus vaccines. @ljiresearch cell.com/cell/fulltext/..." Twitter. https://twitter.com/profshanecrotty/status/1261052353773363200
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psyarxiv.com psyarxiv.com
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Sjåstad, H., Teigen, K. H., & Van Bavel, J. J. (2020, June 5). The best-case heuristic in risk prediction: Hopes and fears in a global health pandemic (COVID-19). https://doi.org/10.31234/osf.io/pcj4f
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www.thelancet.com www.thelancet.com
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Diseases, T. L. I. (2020). COVID-19: Endgames. The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(20)30298-X
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www.vox.com www.vox.com
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Matthews, D. (2020, May 20). How exposing healthy volunteers to Covid-19 for vaccine testing would work. Vox. https://www.vox.com/future-perfect/2020/5/20/21258725/covid-19-human-challenge-trials-vaccine-update-sars-cov-2
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Kurzweil, R. (2020 May 19). AI-Powered Biotech Can Help Deploy a Vaccine In Record Time. Wired. https://www.wired.com/story/opinion-ai-powered-biotech-can-help-deploy-a-vaccine-in-record-time/
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- May 2020
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www.wired.com www.wired.com
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The First Shot: Inside the Covid Vaccine Fast Track. (n.d.). Wired. Retrieved May 30, 2020, from https://www.wired.com/story/moderna-covid-19-vaccine-trials/
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psyarxiv.com psyarxiv.com
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Bertin, P., Nera, K., & Delouvée, S. (2020). Conspiracy beliefs, chloroquine, and the rejection of vaccination: A conceptual replication-extension in the COVID-19 pandemic context [Preprint]. PsyArXiv. https://doi.org/10.31234/osf.io/rz78k
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www.nber.org www.nber.org
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Eichenbaum, M., Rebelo, S., & Trabandt, M. (2020). The Macroeconomics of Epidemics (No. w26882; p. w26882). National Bureau of Economic Research. https://doi.org/10.3386/w26882
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www.sciencemag.org www.sciencemag.org
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Draulans, D. (2020, May 8). ‘Finally, a virus got me.’ Scientist who fought Ebola and HIV reflects on facing death from COVID-19. Science | AAAS. https://www.sciencemag.org/news/2020/05/finally-virus-got-me-scientist-who-fought-ebola-and-hiv-reflects-facing-death-covid-19
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www.thelancet.com www.thelancet.com
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Hargreaves, J., Davey, C., Hargreaves, J., Davey, C., Auerbach, J., Blanchard, J., Bond, V., Bonell, C., Burgess, R., Busza, J., Colbourn, T., Cowan, F., Doyle, A., Hakim, J., Hensen, B., Hosseinipour, M., Lin, L., Johnson, S., Masuka, N., … Yekeye, R. (2020). Three lessons for the COVID-19 response from pandemic HIV. The Lancet HIV, S2352301820301107. https://doi.org/10.1016/S2352-3018(20)30110-7
Tags
- physical distancing
- gender
- is:article
- HIV
- pharmaceutical
- prediction
- social distancing
- infection
- health system
- COVID-19
- lang:en
- response
- socioeconomic status
- trajectory
- inequality
- vaccine
- poverty
- health equity
- policy
- collective behavior
- government
- behavior
- quarentine
- school closure
Annotators
URL
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www.prospectmagazine.co.uk www.prospectmagazine.co.uk
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Rusbridger, Alan. ‘Sage Coronavirus Expert: We’ve Had an Epidemic That to Some Degree Could Have Been Avoided’. Accessed 29 May 2020. https://www.prospectmagazine.co.uk/science-and-technology/alan-rusbridger-sage-jeremy-farrar-covid-19-coronavirus-dominic-cummings-herd-immunity.
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science.sciencemag.org science.sciencemag.org
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Cohen, J., & Kupferschmidt, K. (2020). Countries test tactics in ‘war’ against COVID-19. Science, 367(6484), 1287–1288. https://doi.org/10.1126/science.367.6484.1287
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www.sciencedirect.com www.sciencedirect.com
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Grifoni, A., Weiskopf, D., Ramirez, S. I., Mateus, J., Dan, J. M., Moderbacher, C. R., Rawlings, S. A., Sutherland, A., Premkumar, L., Jadi, R. S., Marrama, D., de Silva, A. M., Frazier, A., Carlin, A., Greenbaum, J. A., Peters, B., Krammer, F., Smith, D. M., Crotty, S., & Sette, A. (2020). Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals. Cell, S0092867420306103. https://doi.org/10.1016/j.cell.2020.05.015
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digest.bps.org.uk digest.bps.org.uk
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New Norms And Difficult Dogs: The Week’s Best Psychology Links. (2020, May 15). BPS. https://digest.bps.org.uk/2020/05/15/new-norms-and-difficult-dogs-the-weeks-best-psychology-links/
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www.nature.com www.nature.com
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Callaway, E. (2020). The race for coronavirus vaccines: A graphical guide. Nature, 580(7805), 576–577. https://doi.org/10.1038/d41586-020-01221-y
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theconversation.com theconversation.com
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Hoffman, T. & Glasziou, P. (2020 May 05). Coronavirus: What if a vaccine doesn’t work? World Economic Forum. https://www.weforum.org/agenda/2020/05/vaccine-coronavirus-alternatives-covid19-vaccinations/
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Hodgson, C. (2020, May 13). WHO’s chief scientist offers bleak assessment of challenges ahead. https://www.ft.com/content/69c75de6-9c6b-4bca-b110-2a55296b0875
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www.nature.com www.nature.com
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Ball, P. (2020). Anti-vaccine movement could undermine efforts to end coronavirus pandemic, researchers warn. Nature, 581(7808), 251–251. https://doi.org/10.1038/d41586-020-01423-4
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science.sciencemag.org science.sciencemag.org
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Cobey, S. (2020). Modeling infectious disease dynamics. Science, 368(6492), 713–714. https://doi.org/10.1126/science.abb5659
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www.health.gov.au www.health.gov.au
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Australian Government Department of Health (2020, April 1). Coronavirus (COVID-19) – Restrictions on entry into and visitors to aged care facilities [Text]. https://www.health.gov.au/resources/publications/coronavirus-covid-19-restrictions-on-entry-into-and-visitors-to-aged-care-facilities
Tags
- elderly
- restriction
- healthcare worker
- Australia
- caregiver
- visitor
- seniors
- vaccine
- flu
- COVID-19
- is:pdf
- aged care facility
- influenza
- lang:en
- vaccination
Annotators
URL
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www.medrxiv.org www.medrxiv.org
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Shental, N., Levy, S., Skorniakov, S., Wuvshet, V., Shemer-Avni, Y., Porgador, A., & Hertz, T. (2020). Efficient high throughput SARS-CoV-2 testing to detect asymptomatic carriers. MedRxiv, 2020.04.14.20064618. https://doi.org/10.1101/2020.04.14.20064618
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www.sciencemediacentre.org www.sciencemediacentre.org
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Expert comments about herd immunity | Science Media Centre. (n.d.). Retrieved April 14, 2020, from https://www.sciencemediacentre.org/expert-comments-about-herd-immunity/
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www.nytimes.com www.nytimes.com
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Bergstrom, C. T., & Dean, N. (2020, May 1). Opinion | What the Proponents of ‘Natural’ Herd Immunity Don’t Say. The New York Times. https://www.nytimes.com/2020/05/01/opinion/sunday/coronavirus-herd-immunity.html
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www.thelancet.com www.thelancet.com
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Makoni, M. (2020). Keeping COVID-19 at bay in Africa. The Lancet Respiratory Medicine, S2213260020302198. https://doi.org/10.1016/S2213-2600(20)30219-8
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- Apr 2020
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www.psychologicalscience.org www.psychologicalscience.org
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Behavioral Strategies More Effective Than Persuasion in Promoting Vaccination. (n.d.). Association for Psychological Science - APS. Retrieved April 30, 2020, from https://www.psychologicalscience.org/news/releases/behavioral-strategies-more-effective-than-persuasion-in-promoting-vaccination.html
Tags
- behavioral strategy
- promotion
- persuasion
- is:news
- factor
- effective
- vaccine
- behavior
- influenza
- lang:en
- vaccine-preventable
- disease
Annotators
URL
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www.medrxiv.org www.medrxiv.org
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Adams, E. R., Anand, R., Andersson, M. I., Auckland, K., Baillie, J. K., Barnes, E., Bell, J., Berry, T., Bibi, S., Carroll, M., Chinnakannan, S., Clutterbuck, E., Cornall, R. J., Crook, D. W., Silva, T. D., Dejnirattisai, W., Dingle, K. E., Dold, C., Eyre, D. W., … Sanchez, V. (2020). Evaluation of antibody testing for SARS-Cov-2 using ELISA and lateral flow immunoassays. MedRxiv, 2020.04.15.20066407. https://doi.org/10.1101/2020.04.15.20066407
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intelligence.weforum.org intelligence.weforum.org
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Forum, W. E. (n.d.). Strategic Intelligence | World Economic Forum. Stategic Intelligence. Retrieved April 24, 2020, from https://intelligence.weforum.org
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www.thelancet.com www.thelancet.com
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Newton, P. N., Bond, K. C., Adeyeye, M., Antignac, M., Ashenef, A., Awab, G. R., Babar, Z.-U.-D., Bannenberg, W. J., Bond, K. C., Bower, J., Breman, J., Brock, A., Caillet, C., Coyne, P., Day, N., Deats, M., Douidy, K., Doyle, K., Dujardin, C., … Zaman, M. (2020). COVID-19 and risks to the supply and quality of tests, drugs, and vaccines. The Lancet Global Health, S2214109X20301364. https://doi.org/10.1016/S2214-109X(20)30136-4
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eppi.ioe.ac.uk eppi.ioe.ac.uk
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Evidence Tracker: COVID-19
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www.canada.ca www.canada.ca
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Government of Canada. (2020). Government of Canada funds 49 additional COVID-19 research projects – Details of the funded projects. Canada.ca. https://www.canada.ca/en/institutes-health-research/news/2020/03/government-of-canada-funds-49-additional-covid-19-research-projects-details-of-the-funded-projects.html
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sciencebusiness.net sciencebusiness.net
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EU boosts efforts to adjust R&D programmes to virus crisis. (n.d.). Science|Business. Retrieved April 15, 2020, from https://sciencebusiness.net/news/eu-boosts-efforts-adjust-rd-programmes-virus-crisis
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www.imperial.ac.uk www.imperial.ac.uk
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Coronavirus misinformation and vaccine research among key priorities for public | Imperial News | Imperial College London. (n.d.). Imperial News. Retrieved April 8, 2020, from https://www.imperial.ac.uk/news/196696/coronavirus-misinformation-vaccine-research-among-priorities/
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www.ukri.org www.ukri.org
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Open Letter to the Research and Innovation Community—UK Research and Innovation. (n.d.). Retrieved April 9, 2020, from https://www.ukri.org/news/open-letter-to-the-research-and-innovation-community/
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novonordiskfonden.dk novonordiskfonden.dk
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Societal Responses to and Preparedness for Emerging Viral Infections – 2020. (n.d.). Novo Nordisk Fonden. Retrieved April 16, 2020, from https://novonordiskfonden.dk/da/grants/societal-responses-to-and-preparedness-for-emerging-viral-infections-2020/
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www.wwtf.at www.wwtf.atCOVID-191
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COVID-19. (n.d.). Retrieved April 17, 2020, from https://www.wwtf.at/covid/index.php?lang=EN
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www.ukri.org www.ukri.org
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COVID-19 therapy, vaccine, epidemiology and policy development research boosted by twenty-one new projects—UK Research and Innovation. (n.d.). Retrieved April 21, 2020, from https://www.ukri.org/news/covid-19-research-boosted-by-new-projects/
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Callaway, E. (2020). Should scientists infect healthy people with the coronavirus to test vaccines? Nature, 580(7801), 17–17. https://doi.org/10.1038/d41586-020-00927-3
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twitter.com twitter.com
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Daniel Summers, MD en Twitter: “‘Social distancing was unnecessary’ is the new ‘why should we vaccinate against diseases nobody gets any longer?’ https://t.co/kgB2Rwi4W8” / Twitter. (n.d.). Twitter. Retrieved April 21, 2020, from https://twitter.com/wfkars/status/1248220267115134978
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- Mar 2017
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www.todayifoundout.com www.todayifoundout.com
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Can the flu vaccine give you the flu? As you might have guessed already given our description of how flu vaccines are made, the answer is unequivocally no- you’re not going to get the flu from the flu vaccine
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- Aug 2016
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www.sciencebasedmedicine.org www.sciencebasedmedicine.org
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Credibull score = 6.52 / 10
To provide feedback on the score fill in the form available here
What is Credibull? getcredibull.com
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www.sciencebasedmedicine.org www.sciencebasedmedicine.org
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Credibull score = 6.44 / 10
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What is Credibull? getcredibull.com
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www.davidwolfe.com www.davidwolfe.com
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Credibull score = 1.01 / 10
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What is Credibull? getcredibull.com
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www.australiannationalreview.com www.australiannationalreview.com
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Credibull score = 0.58 / 10
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What is Credibull? getcredibull.com
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articles.mercola.com articles.mercola.com
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Credibull score = 2.79 / 10
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What is Credibull? getcredibull.com
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articles.mercola.com articles.mercola.com
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Credibull score = 1.68 / 10
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What is Credibull? getcredibull.com
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www.autismspeaks.org www.autismspeaks.org
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Credibull score = 6.10 / 10
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What is Credibull? getcredibull.com
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www.vaccinateyourbaby.org www.vaccinateyourbaby.org
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Credibull score = 6.56 / 10
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What is Credibull? getcredibull.com
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www.skepticalraptor.com www.skepticalraptor.com
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Credibull score = 4.46 / 10
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What is Credibull? getcredibull.com
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www.voicesforvaccines.org www.voicesforvaccines.org
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Credibull score = 5.04 / 10
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What is Credibull? getcredibull.com
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www.autismspeaks.org www.autismspeaks.org
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Credibull score = 5.58 / 10
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What is Credibull? getcredibull.com
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www.cdc.gov www.cdc.gov
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Credibull score = 8.18 / 10
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What is Credibull? getcredibull.com
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www.pbs.org www.pbs.org
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Credibull score = 3.86 / 10
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What is Credibull? getcredibull.com
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www.naturalnews.com www.naturalnews.com
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Credibull score = 0.10 / 10
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What is Credibull? getcredibull.com
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www.huffingtonpost.com www.huffingtonpost.com
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Credibull score = 0.61 / 10
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www.ibtimes.co.uk www.ibtimes.co.uk
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Credibull score = 3.74 / 10
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What is Credibull? getcredibull.com
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Credibull score = 1.73 / 10
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What is Credibull? getcredibull.com
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immunise.health.gov.au immunise.health.gov.au
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Credibull score = 5.63 / 10
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What is Credibull? getcredibull.com
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en.wikipedia.org en.wikipedia.org
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Credibull score = 8.03 / 10
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What is Credibull? getcredibull.com
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www.publichealth.org www.publichealth.org
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Credibull score = 6.13 / 10
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What is Credibull? getcredibull.com
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- Jan 2015
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How interesting! It's the same in my family. Certain members will take as gospel, the opinions of the people they deem to have credibility, but eschew - and even satirically cauterize - the wisdom and factual evidence of people with the authority and knowledge.
It's most frustrating. As for me, I try not to read comments. They just make me so angry!
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