614 Matching Annotations
  1. Jan 2022
    1. Home

      Zuo, F., Abolhassani, H., Du, L., Piralla, A., Bertoglio, F., Campos-Mata, L. de, Wan, H., Schubert, M., Wang, Y., Sun, R., Cassaniti, I., Vlachiotis, S., Kumagai-Braesch, M., Andréll, J., Zhang, Z., Xue, Y., Wenzel, E. V., Calzolai, L., Varani, L., … Pan-Hammarström, Q. (2022). Heterologous immunization with inactivated vaccine followed by mRNA booster elicits strong humoral and cellular immune responses against the SARS-CoV-2 Omicron variant (p. 2022.01.04.22268755). https://doi.org/10.1101/2022.01.04.22268755

    1. Barry McAree 💙. (2022, January 6). Teachers on these islands will get FFP2(rightly so).Healthcare workers on other parts of these islands..nah!..Surgical masks/spit guards/not PPE,for working with COVID-positive patients risking other patient’s, our own & our family’s health.”Protect the NHS”🤔⁦@CMO_England⁩ https://t.co/OngrD5BBPU [Tweet]. @BarryMcAree. https://twitter.com/BarryMcAree/status/1478883258305814536

  2. Dec 2021
    1. In 2022, successful business leaders will need to address the continued disruption from the last couple of years and will do so through four human-centric strategies. All of them elevate the importance of individuals. All of them improve the employee-employer relationship. All of them test the degree to which leaders embrace innovative management styles. All of them will impact the company's ability to retain and recruit top talent. And all of them have an impact on a business's bottom line

      It seems like them uncertainty in the world today makes need of higher quality relationships between the employers and their boss as they cannot find it in the systems to the same degree. It will be a time when the character of the leader is tested and the leader will then be in need of a greater input from God or an external source which is stable.

  3. Nov 2021
    1. WHO/Europe. (2021, October 19). Are you a Mask Master? 😷 Take this quick quiz to find out 👉 https://bit.ly/3jbn5iS Wearing a well-fitted mask, along with practicing other prevention measures, is an important part of slowing the spread of #COVID19 High quiz scores = Mask Master badge 🎖 https://t.co/0PzSsgsBfD [Tweet]. @WHO_Europe. https://twitter.com/WHO_Europe/status/1450451677098790916

    1. Walter, E. B., Talaat, K. R., Sabharwal, C., Gurtman, A., Lockhart, S., Paulsen, G. C., Barnett, E. D., Muñoz, F. M., Maldonado, Y., Pahud, B. A., Domachowske, J. B., Simões, E. A. F., Sarwar, U. N., Kitchin, N., Cunliffe, L., Rojo, P., Kuchar, E., Rämet, M., Munjal, I., … Gruber, W. C. (2021). Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age. New England Journal of Medicine, NEJMoa2116298. https://doi.org/10.1056/NEJMoa2116298

  4. Oct 2021
  5. Sep 2021
  6. Aug 2021
    1. I really hope they keep breaking it. Being the lead on a library for several years, most of the forced refactors were pretty straight forward and in almost every case made our code either more sound or easier to be consumed. Now I work on a runtime that embeds TypeScript and 3.5.1 has broken some code, thought it took me all of about 15 minutes to make the changes to adopt it, and in every case, it broke because we were being a bit loose with the types. While it didn't find any bugs, it made the code more "safe".

      I really hope they keep breaking it.

    1. (2) Dr Nicole E Basta on Twitter: “There is SO MUCH misunderstanding about what a #vaccine #mandate IS & what a vaccine mandate DOES. No one is calling for anyone to be banned. No one is calling for anyone to be forcibly vaccinated. Please, gather 'round and listen up, so you know what we’re talking about... 1/n” / Twitter. (n.d.). Retrieved August 23, 2021, from https://twitter.com/IDEpiPhD/status/1428410251884302336?s=20

    1. Madhi, S. A., Koen, A. L., Izu, A., Fairlie, L., Cutland, C. L., Baillie, V., Padayachee, S. D., Dheda, K., Barnabas, S. L., Bhorat, Q. E., Briner, C., Aley, P. K., Bhikha, S., Hermanus, T., Horne, E., Jose, A., Kgagudi, P., Lambe, T., Masenya, M., … Kwatra, G. (2021). Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in people living with and without HIV in South Africa: An interim analysis of a randomised, double-blind, placebo-controlled, phase 1B/2A trial. The Lancet HIV, 0(0). https://doi.org/10.1016/S2352-3018(21)00157-0

    1. Tenbusch, M., Schumacher, S., Vogel, E., Priller, A., Held, J., Steininger, P., Beileke, S., Irrgang, P., Brockhoff, R., Salmanton-García, J., Tinnefeld, K., Mijocevic, H., Schober, K., Bogdan, C., Yazici, S., Knolle, P., Cornely, O. A., Überla, K., Protzer, U., … Wytopil, M. (2021). Heterologous prime–boost vaccination with ChAdOx1 nCoV-19 and BNT162b2. The Lancet Infectious Diseases, 0(0). https://doi.org/10.1016/S1473-3099(21)00420-5

  7. Jul 2021
    1. Gargano, J. W., Wallace, M., Hadler, S. C., Langley, G., Su, J. R., Oster, M. E., Broder, K. R., Gee, J., Weintraub, E., Shimabukuro, T., Scobie, H. M., Moulia, D., Markowitz, L. E., Wharton, M., McNally, V. V., Romero, J. R., Talbot, H. K., Lee, G. M., Daley, M. F., & Oliver, S. E. (2021). Use of mRNA COVID-19 Vaccine After Reports of Myocarditis Among Vaccine Recipients: Update from the Advisory Committee on Immunization Practices — United States, June 2021. MMWR. Morbidity and Mortality Weekly Report, 70(27), 977–982. https://doi.org/10.15585/mmwr.mm7027e2

  8. Jun 2021
    1. Jeremy Faust MD MS (ER physician) on Twitter: “Number of Covid cases among children in US: >4 million. Number of Covid deaths in US children: 300-400. Number of kids vaccinated: 7 million. Number of kids who died from vaccine-related myocarditis: Zero. #vaccinate @bhrenton @RickABright @angie_rasmussen @celinegounder” / Twitter. (n.d.). Retrieved June 28, 2021, from https://twitter.com/jeremyfaust/status/1408880589319647243?s=20

    1. Michael Makris on Twitter: “The cumulative incidence of VITT after AZ first vaccination in the UK is continuing to increase with the latest data being 1 in 81,000. However this is rather misleading because VITT is age related with a higher incidence in the young. Https://t.co/CSjshAoRsN” / Twitter. (n.d.). Retrieved June 27, 2021, from https://twitter.com/ProfMakris/status/1395457748721184777?s=20

  9. May 2021
    1. Gobeil, P., Pillet, S., Séguin, A., Boulay, I., Mahmood, A., Vinh, D. C., Charland, N., Boutet, P., Roman, F., Most, R. V. D., Perez, M. de los A. C., Ward, B. J., & Landry, N. (2021). Interim Report of a Phase 2 Randomized Trial of a Plant-Produced Virus-Like Particle Vaccine for Covid-19 in Healthy Adults Aged 18-64 and Older Adults Aged 65 and Older. MedRxiv, 2021.05.14.21257248. https://doi.org/10.1101/2021.05.14.21257248

    1. but there was no difference in levels of withdrawal between those on NRT patches and those on placebo.

      Data like this seems to be definitive proof that nicotine is nothing like tobacco. I'm not aware of any evidence that nicotine itself is addictive, save for a few anecdotes. I don't put much stock in these anecdotes because people also report habit-withdrawal symptoms when they quit zero nicotine e-juice. That is to say, without placebo controls we cannot conclude drug withdrawal is the cause because it can also be explained by psychology.

      That said, I'm reasonably certain that nicotine contributes to tobacco addiction. While I think nicotine is fairly non-addictive, I believe it enhances the addictiveness of other drugs. I think this is partly due to an entourage effect that alters the high, and also a memory-enhancing effect so one remembers the high more vividly.

    1. The foremost consideration with respect to teaching of the Australian Aboriginal memory technique is the cultural safety aspect and respect for the peoples who developed this approach. In our program, the teaching of this program was administered by an experienced Australian Aboriginal Educator, who was able to integrate the method into our teaching program, while simultaneously preventing several breaches of cultural etiquette and terminology which could easily have compromised the material had it been delivered by a non-Australian Aboriginal educator (TY), however well-intentioned. The need for a deep knowledge and understanding of the appropriate context for teaching and delivery of this material is probably the main factor which would preclude more widespread adoption of this technique.

      I really appreciate the respect given to indigenous knowledge here.

      The researchers could have gone much further in depth in describing it and the aspects of what they mean by cultural "safety". They've done a disservice here by downplaying widespread adoption. Why not? Why couldn't we accord the proper respect of traditions to actively help make these techniques more widespread? Shouldn't we be willing to do the actual work to accord respect and passing on of these knowledges?

      Given my reading in the area, there seems to be an inordinate amount of (Western) "mysticism" attributed to these techniques (here and in the broader anthropology literature) rather than approaching them head-on from a more indigenous perspective. Naturally the difficult part is being trusted enough by tribal elders to be taught these methods to be able to pass them on. (Link this idea to Tim Ingold's first chapter of Anthropology: Why It Matters.)

      All this being said, the general methods known from the West, could still be modified to facilitate in widespread adoption of those techniques we do know. Further work and refinement of them could continue apace while still maintaining the proper respect of other cultures and methods, which should be the modern culture default.

      If nothing else, the West could at least roll back the educational reforms which erased their own heritage to regain those pieces. The West showing a bit of respect for itself certainly wouldn't be out of line either.

  10. Apr 2021
  11. Mar 2021
    1. Yufika, A., Wagner, A. L., Nawawi, Y., Wahyuniati, N., Anwar, S., Yusri, F., Haryanti, N., Wijayanti, N. P., Rizal, R., Fitriani, D., Maulida, N. F., Syahriza, M., Ikram, I., Fandoko, T. P., Syahadah, M., Asrizal, F. W., Aletta, A., Haryanto, S., Jamil, K. F., … Harapan, H. (2020). Parents’ hesitancy towards vaccination in Indonesia: A cross-sectional study in Indonesia. Vaccine, 38(11), 2592–2599. https://doi.org/10.1016/j.vaccine.2020.01.072

  12. Feb 2021
    1. Youyang Gu. (2021, February 24). When can we return to normal? Forget about ‘herd immunity’. Below is my estimate for the number of susceptible individuals over time, as a proportion of the US population. Looking at this graph, what is the best point to go back to normal? Christmas? Fall? Or Summer? 🧵 https://t.co/V4uiFk5YcP [Tweet]. @youyanggu. https://twitter.com/youyanggu/status/1364627872233750543

  13. Jan 2021
    1. Sadoff, J., Le Gars, M., Shukarev, G., Heerwegh, D., Truyers, C., de Groot, A. M., Stoop, J., Tete, S., Van Damme, W., Leroux-Roels, I., Berghmans, P.-J., Kimmel, M., Van Damme, P., de Hoon, J., Smith, W., Stephenson, K. E., De Rosa, S. C., Cohen, K. W., McElrath, M. J., … Schuitemaker, H. (2021). Interim Results of a Phase 1–2a Trial of Ad26.COV2.S Covid-19 Vaccine. New England Journal of Medicine, 0(0), null. https://doi.org/10.1056/NEJMoa2034201

  14. Dec 2020
    1. Thus, just as humans built buildings and bridges before there was civil engineering, humans are proceeding with the building of societal-scale, inference-and-decision-making systems that involve machines, humans and the environment. Just as early buildings and bridges sometimes fell to the ground — in unforeseen ways and with tragic consequences — many of our early societal-scale inference-and-decision-making systems are already exposing serious conceptual flaws.

      Analogous to the collapse of early bridges and building, before the maturation of civil engineering, our early society-scale inference-and-decision-making systems break down, exposing serious conceptual flaws.

    1. Voysey, M., Clemens, S. A. C., Madhi, S. A., Weckx, L. Y., Folegatti, P. M., Aley, P. K., Angus, B., Baillie, V. L., Barnabas, S. L., Bhorat, Q. E., Bibi, S., Briner, C., Cicconi, P., Collins, A. M., Colin-Jones, R., Cutland, C. L., Darton, T. C., Dheda, K., Duncan, C. J. A., … Zuidewind, P. (2020). Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: An interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK. The Lancet, 0(0). https://doi.org/10.1016/S0140-6736(20)32661-1

    1. Helminths are multicellular worms (for example, tapeworms and roundworms). Helminths reproduce by releasing eggs; animals may consume the eggs which then develop into larvae that can survive even after the animal is killed. Eating raw or undercooked meat can lead to ingesting the larvae. Thorough cooking destroys the larvae.

      Helminths are worms

    2. Additional symptoms may include vomiting, dehydration, lightheadedness, and rapid heartbeat. More severe complications can include a high fever, diarrhea that lasts more than three days, prolonged vomiting, bloody stools, and signs of shock.

      Symptoms of food poison

  15. Nov 2020
    1. How can we help our students feel safe?

      I feel like this question needs to be asked more. We talk about our classrooms as being places where it should be "safe" to take risks and to fail, but it's not enough for us to assert it, and I'd argue not enough for us to implement only the policies which would address our own concerns. We really have to ask how our students perceive their safety.

  16. Oct 2020
    1. Landi, F., Marzetti, E., Sanguinetti, M., Ciciarello, F., Tritto, M., Benvenuto, F., Bramato, G., Brandi, V., Carfì, A., D’Angelo, E., Fusco, D., Lo Monaco, M. R., Martone, A. M., Pagano, F., Rocchi, S., Rota, E., Russo, A., Salerno, A., Cattani, P., … Bernabei, on behalf of the G. A. C.-19 G. T. (n.d.). Should face masks be worn to contain the spread of COVID-19 in the postlockdown phase? Transactions of The Royal Society of Tropical Medicine and Hygiene. https://doi.org/10.1093/trstmh/traa085