165 Matching Annotations
  1. Dec 2024
    1. in my view it's absolutely clear that even talking about this now I'm not saying we shouldn't talk about it and this is a bit dilemma but even talking about it this will already be feeding into Delayed Action elsewhere in the same way that negative emission Technologies sucking CO2 out the air has actually undermined the need for Action that has undermined the scale of the challenge that the climate scientists the academics the experts have said is now necessary

      for - climate crisis - plan B - always has tendency to undermine Plan A and cause delayed action - ie. Negative Emissions Technologies - Kevin Anderson

  2. Oct 2024
    1. Disease: Von Willebrand Disease (VWD) type 1

      Patient(s): 13 yo, female and 14 yo, female, both Italian

      Variant: VWF NM_000552.5: c.820A>C p. (Thr274Pro)

      Dominant negative effect

      Heterozygous carrier

      Variant located in the D1 domain on VWF

      Phenotypes:

      heterozygous carriers have no bleeding history

      reduced VWF levels compatible with diagnosis of VWD type 1

      increased FVIII:C/VWF:Ag ratio, suggests reduced VWF synthesis/secretion as possible phathophysiological mechanism

      Normal VWFpp/VWF:Ag ratio

      Modest alteration of multimeric pattern in plasma and platelet multimers

      plasma VWF showed slight increase of LMWM and decrease of IMWM and HMWM

      Platelet VWF showed quantitative decrease of IMWM, HMWM, and UL multimers

      In silico analysis:

      SIFT, ALIGN, GVD Polyphen 2.0, SNP&GO, Mutation Taster, Pmut all suggest damaging consequences.

      PROVEAN and Effect suggest neutral effect

      according to ACMG guidelines this variant was classified as pathogenic

  3. Sep 2024
    1. Disease: Von Willebrand Disease (VWD)

      Patient: 18 yo, Male, heterozygote

      Variant: VWF NM_000552.5: c.5456_5842del p.(R1819_C1948delinsS)

      Was not present in gnomAD when searched

      Dominant negative effect

      Phenotypes:

      lower collagen-binding capacity

      History of bleeding (epistaxis)

      gum bleeding

      cutaneous bruises

      ADAMTS13 resistant

      Family: Mother, father, sister are asymptomatic

      Suggested as de novo, no picture found in patient's relative of the deletion, loss of A3 loop

    1. Die Fossilindustrie finanziert seit Jahrzehten Universitäten und fördert damit Publikationen in ihrem Interesse, z.B. zu false solutions wie #CCS. Hintergrundbericht anlässlich einer neuen Studie: https://www.theguardian.com/business/article/2024/sep/05/universities-fossil-fuel-funding-green-energy

      Studie: https://doi.org/10.1002/wcc.904

  4. Jul 2024
    1. I think people need to understand we are up against an event 00:36:00 that is one of six in Earth's history like hurtling towards it at an outrageous Pace in order to kind of galvanize especially leaders

      for - need for reporting negative news - galvanize support

  5. May 2024
    1. What could possibly go wrong? Dear Stack Overflow denizens, thanks for helping train OpenAI's billion-dollar LLMs. Seems that many have been drinking the AI koolaid or mixing psychedelics into their happy tea. So much for being part of a "community", seems that was just happy talk for "being exploited to generate LLM training data..." The corrupting influence of the profit-motive is never far away.
  6. Feb 2024
  7. Jan 2024
  8. Dec 2023
    1. The problem with this pile of questions is that, instead of helping the OP get out of the X Y problem, people stay focussed on Y, mark the question as a duplicate of Y in a matter of minutes and X is never properly addressed.

      sticking too much to policy/habit instead of addressing the specific needs of individuals? too much eagerness to close / mark as duplicate?

  9. Oct 2023
    1. 𝑟=−𝑥2 + 𝑦2‾‾‾‾‾‾‾‾√r=−x2 + y2r = -\sqrt{x^2 ~+~ y^2} (i.e. 𝑟rr is negative)

      Given that r is a polar coordinate, r cannot be negative, otherwise it would mean that the polar coordinate system would not be orthogonal, which it is.

    2. convention that 𝑟rr can be negative, by defining (−𝑟,𝜃)=(𝑟,𝜃+180∘)(−r,θ)=(r,θ+180∘)(-r,\theta) = (r,\theta + 180^\circ) for any angle 𝜃θ

      One cannot adopt a convention that contradicts the definition of "coordinates" and the fact that for orthogonal coordinate systems each coordinate do not depend on any other coordinate, otherwise, it would mean that the coordinate system is not orthogonal.

      For this reason, negative r is not a coordinate of a polar coordinate systems, since it needs pi in the angle coordinate, expressed as -r = (r, pi) and that the polar coordinate system is an orthogonal coordinate system.

      Calling -r a coordinate is a travesty.

  10. Aug 2023
    1. Indigenous cultures can "see" dark constellations (example: the Australian emu in the sky) which are defined empty spaces which are explicitly visible.

      Using this concept, one could think of or use blank index cards in a zettelkasten or even the empty (negative) spaces between cards as "dark ideas" (potential ideas which need to be thought of and filled in).

      Link to: https://hypothes.is/a/FlqusEN1Ee6XEr_9StPUlA

    1. This is not to say the technology cannot be made to work at scale, but it is incorrect and risks being misleading to give the impression the technology is tried and tested at scale, let alone economic compared with the alternatives.
      • for: greenwashing, CCS, NET, negative emissions technologies
      • comment
        • one could interpret CCS as an oil industry attempt to greenwash and create the appearance of doing something when it is really just tinkering at the margins
        • it is an excuse that gives the appearance of being concerned which allows for BAU to continue
        • dangling the carrot of "future breakthrough" of CCS is much like all the rest of negative emissions technologies (NET)
  11. Jul 2023
    1. one of the things I think Civil Society has to be aware of is that there's been 00:09:33 a deliberate misuse of the prospects of technology
      • for: net zero, kick the can down the road, green growth, degrowth, NET, negative emissions technology
  12. Apr 2023
    1. If there’s a force that’s driving us toward greater complexity, there seems to be an opposing force, a force of destruction that uses competition for ill. The way I see it, Moloch is the god of unhealthy competition, of negative sum games.

      Quotation - If there's a force that's driving us toward greater complexity - there seems to be an opposing force, - a force of destruction that uses competition for ill. - The way I see it, - Moloch is the god of unhealthy competition, of negative sum games

  13. Mar 2023
    1. I rolled back your edit because the double negative was very deliberate - I explicitly would not claim correctness, just lack of clear incorrectness
  14. Feb 2023
    1. They write a bunch of crap down that they wish they’d be able to do (secretly knowing they never will) and then their task manager gets overwhelming and they drop it because there is too much noise. This is why systems like Bullet Journal thrive in a digital world. When something is too hard to migrate to a new page or notebook, you just said it’s not worth doing and you let it go. Bullet Journal is a no-first system.

      Bullet journaling works well in a noisy world because it forces people to confront what they're eventually not going to do anyway and gets them to drop it rather than leaving it on an ever-growing list.

      Carrying forward to do lists manually encourages one to quit things that aren't going to get done.

  15. Jan 2023
    1. https://www.npr.org/sections/health-shots/2023/01/18/1139783203/what-makes-songs-swing-physicists-unravel-jazz-mystery

      Spaces in both language, text, and music help to create the texture of what is being communicated (and/or not).


      Link to Edward Tufte's latest book in section entitled "Spacing enhances complex meaning, encourages slow, thoughtful reading":

      <small><cite class='h-cite via'> <span class='p-author h-card'>KevinMarks</span> in #meta 2023-01-19 (<time class='dt-published'>01/19/2023 11:32:19</time>)</cite></small>


      Link to Indigenous astronomy example of negative spaces (like the Great Emu)

    1. Expansion is led by focus. By taking time to edit, carve up, and refactor our notes, we put focus on ideas. This starts the Great Wheel of Positive Feedback. All hail to the Great Wheel of Positive Feedback.

      How can we better thing of card indexes as positive feedback mechanisms? Will describes it as the "Great Wheel of Positive Feedback" which reminds me a bit of flywheels for storing energy for later use.

  16. Oct 2022
    1. This search for order pushes one to seek out under-lying patterns and trends, to find relations that may betypical and causal.

      Finding order and relations (and their particular types), is a form of linking ideas found in some of the more complex zettelkasten and knowledge management spaces. It's not as explicit here and he doesn't seem to be focusing on stating or writing explicit links within his notes. He does, however, place some focus on the quality and types of links he's making (or at least thinking about), something which isn't frequently seen in the current PKM space. For example, no one is creating user interfaces that show links between ideas which are opposite (or in opposition or antonym relation) to each other.

  17. Aug 2022
  18. Jul 2022
    1. So what can we make of politicians who continue to argue that ‘1.5°C is still alive’? Are they misinformed or are they simply lying?I believe many are in denial about the types of solutions the climate crisis demands. Rather than do the – admittedly – very difficult political work of eking out our supplies of fossil fuels while accelerating a just transition to post-carbon societies, politicians are going all out on technological salvation. This is a new form of climate denial, which involves imagining large-scale carbon dioxide removal that will clean up the carbon pollution that we continue to pump into the atmosphere. While it may seem much safer to stick to the script and say that it is still physically possible to limit warming to no more than 1.5°C, while pointing out that the scale of change demands much more political will, I believe that this can no longer be a credible response to the climate crisis.We have warmed the climate by 1.2°C since pre-industrial periods. If emissions stay flat at current levels, then in around nine years the carbon budget for 1.5°C will be exhausted. And, of course, emissions are not flat – they are surging. 2021 saw the second-largest annual increase ever recorded, driven by the rebound in economic activity after Coronavirus lockdowns. We did not ‘build back better’.The clock has been stuck at five minutes to midnight for decades. Alarms have been continuing to sound. There are only so many times you can hit the snooze button.

      Going all out on technological salvation is a form of climate denialism.

      We are at 1.2 Deg C and emissions have climbed after rebounding after Covid. If they flatline for the next nine years, we will hit 1.5 Deg C.

  19. Jun 2022
    1. first i think it's important to remember that net zero is a new phrase it's it's nothing we haven't had newton this language of net zero this framing of net zero is is something just appeared just in 00:11:54 the last few years if you look at the sr 1.5 report 2018 in the summary for policy makers then um it's mentioned 16 times if you look at the ar-5 the previous report from the ipcc and their synthesis report 00:12:06 for the summary for policy makers it's not mentioned once you look in the the committee on climate uk committee on climate change's sixth budget report and it's it's a long report 427 pages 00:12:18 it's on numerous times on every page it's somewhere between it's referred to somewhere between three thousand and five thousand times they use the expression net zero look at the previous fifth budget report from the committee on 00:12:31 climate change in 2015 it's not mentioned once now it is true to say that the language of net cumulative missions in various ways has been referred to if you like within the science but the appealing translation and the 00:12:44 ubiquitous use of net zero by everyone is a very new phenomena and one i think that we've taken on board unproblematically because it allows us to to basically um avoid near-term action on climate 00:12:57 change and we can hide all sorts behind it so it's important to recognize that net zero net zero 2050 net zero 20 20 45 for sweden firstly this is not based on the concept of a total carbon budget 00:13:10 and it's interesting note that the uk previously had legislation that was based on the total carbon budget for the uk as i mean i think the budget was too large but it was deemed to be an appropriate contribution to staying below 2 degrees centigrade but now 00:13:24 that's gone now we simply have this net zero 2050 framing so this whole language it moves the debate from what we need to do today which is what carbon budgets force us to 00:13:36 face it moves it off to some far-off point 2045 or 2050 which we have to think about that in which which policymakers in sweden and the uk will still be policymakers in 2045 and 50 they'll either be dead 00:13:49 or retired as indeed with the scientists that are behind a lot of this net zero language so it's in that sense it's we are passing that net zero is a is a generational passing of the challenge of the buck um to our children and our children's 00:14:02 children it's also worth bearing in mind that net zero typically assumes some sort of multi-layered form of substitution between different greenhouse gases so carbon dioxide for me thing between different sources 00:14:15 carbon dioxide from a car can be compared with agricultural fertilizer and nitrous oxide emissions but these these are very different things but across decades a flight carbon dioxide 00:14:27 from a flight we take today can be considered in relation to carbon capture in a tree that's planted in 2050 that's growing in 2070. this assumption within net zero that a ton is a ton is a ton regardless of different 00:14:40 chemistries different atmospheric lifetimes of the gases in the atmosphere and and different levels of certainty and indeed levels of risk and hugely different things this is this is incredibly dangerous and again it's another 00:14:52 it's another thing that makes net zero attractive and appealing in a machiavellian way because it allows us to hide all sorts of things behind this language of net zero the other thing about net zero is that 00:15:07 perhaps with no exceptions but typically anyway it relies on huge planetary scale carbon dioxide removal cdrs often well that's the latest acronym i'm sure there'll be another one out in the next year or two 00:15:20 um carbon dioxide removal captures two important elements first negative emission technologies nets as they're often referred to and second nature-based solutions um nbs so these two approaches one is sort of 00:15:32 using technology to remove carbon dioxide from the atmosphere and the other one is using various nature-based approaches like planting trees or peat bog restoration and things like this that are claimed to absorb carbon dioxide 00:15:45 and just to get a sense of the scale of negative emissions that's assumed in almost every single 1.5 and 2 degree scenario at the global level but indeed at national levels as well we're typically assuming hundreds of 00:15:57 billions of tons of carbon dioxide being absorbed from the atmosphere most of it is post 2050 and quite a lot of it is beyond 2100 again look at those dates who in the scientific community that's 00:16:09 promoting these who in the policy realm that's promoting these is going to be still at work working in 2015 and 2100 some of the early career researchers possibly some of the younger policymakers but most of us will 00:16:21 will say be dead or um or retired by them and just have another flavor if those numbers don't mean a lot to you what we're assuming here is that technologies that are today at best small pilot schemes will be 00:16:34 ramped up in virtually every single scenario to something that's that's akin to the current um global oil and gas industry that sort of size now that would be fine if it's one in ten scenarios or you know five and a 00:16:47 hundred scenarios but when virtually every scenario is doing that it demonstrates the deep level of systemic bias that we've got now that we've all bought into this language of net zero so it's not to outline my position on 00:16:59 carbon dioxide removal because it's often said that i'm opposed to it and that's simply wrong um i i would like just to see a well-funded research and development programs into negative emission technologies nature-based solutions and so forth 00:17:12 and potentially deploy them if they meet stringent sustainability criteria and i'll just reiterate that stringent sustainability criteria but we should mitigate we should cut our emissions today assuming that these carbon dioxide removal techniques of one 00:17:25 sort or another do not work at scale and another important factor to bear in mind here and there's a lot of double counting that gotham goes on here as far as i can tell anyway is that we're going to require some level of carbon 00:17:36 dioxide removal because there's going to be a lot of residual greenhouse gas emissions not you know not co2 principally methane and n2o nitroxites and fertilizer use um we're going to come from agriculture anyway if you're going to feed 9 billion 00:17:49 people now quite what those numbers are there's a lot of uncertainty but somewhere probably around 6 to 10 billion tons of carbon dioxide equivalent every single year so we'll have to find some way of compensating for the warming from feeding the world's population and certainly there are plenty of things we 00:18:01 can do with our food eating habits and with our agricultural practices but nonetheless it still looks like there will be a lot of emissions from the agricultural sector and therefore we need to have real zero emissions 00:18:14 from energy we cannot be using all of these other techniques nets mbs and so forth to allow us to carry on with our high energy use net zero has become if you like a policy 00:18:28 framework for all and some argue and there's been some question discussion in some of the um journalist papers around climate change recently saying well actually that's what it's one of its real strengths is it brings everyone together 00:18:40 but in my view it it's so vague that it seriously undermines the need for immediate and deep cuts and emissions so i can see some merit in a in an approach that does bring people together but if it sells everything out in that process then i think it's actually more 00:18:53 dangerous than it is of benefit and i think net zero very much falls into that category i just like to use the uk now as an example of why i come to that conclusion

      Suddenly the new term "Net Zero" was introduced into this IPCC report thousands of times. Kevin unpacks how misleading this concept could be, allowing business and governments to kick the can down the road and not make any real effort towards GHG reductions today. Procrastination that is deadly for our civilization.

      At time 15 minute, Kevin goes into Carbon Dioxide Removal (CDR) and Negative Emission Technologies

      (NET) which are an important part of the Net Zero concept. These are speculative technologies at best which today show no sign of scalability.

    1. *The compass*

      I too have seen this before, though the directions may have been different.

      When thinking about an idea, map it discretely. North on the compass rose is where the idea comes from, South is where it leads to, West leads to things similar to the idea while East are ideas that are the opposite of it.

      This is useful in situating information, particularly with respect to the similarities and opposites. One must generally train themselves to think about the opposites.

      Many of the directions are directly related to putting information into a zettelkasten, in particular where X comes from (source), where it leads (commentary or links to other ides), what's similar to x are links to either closely related ideas or to an index. The opposite of X is the one which is left out in this system too.

      *The compass*: <br>Saw that one before. Ugh, didn't like it.<br><br>Thinking about it though, it's a fitting metaphor to look at a note from different directions. I'm going to add this to my notes template(Just to try). All my notes have North & could use some other perspectives 🎉<br><br>🧶4/4 pic.twitter.com/CJctmC5Y39

      — Alex Qwxlea (@QwxleaA) June 14, 2022
      <script async src="https://platform.twitter.com/widgets.js" charset="utf-8"></script>

      Link to - Indigenous map conceptualizations - direction finding - method of loci

  20. May 2022
    1. For example, we know one of the ways to make people care about negative externalities is to make them pay for it; that’s why carbon pricing is one of the most efficient ways of reducing emissions. There’s no reason why we couldn’t enact a data tax of some kind. We can also take a cautionary tale from pricing externalities, because you have to have the will to enforce it. Western Canada is littered with tens of thousands of orphan wells that oil production companies said they would clean up and haven’t, and now the Canadian government is chipping in billions of dollars to do it for them. This means we must build in enforcement mechanisms at the same time that we’re designing principles for data governance, otherwise it’s little more than ethics-washing.

      Building in pre-payments or a tax on data leaks to prevent companies neglecting negative externalities could be an important stick in government regulation.

      While it should apply across the board, it should be particularly onerous for for-profit companies.

    2. There’s many examples around the world of communities banding together to collectively govern a shared resource, like forestry, grazing grounds, and wells.

      If we all take action to do these things collectively, then it isn't a "tax" on any individual or corporation.

    1. I returned to another OER Learning Circle and wrote an ebook version of a Modern World History textbook. As I wrote this, I tested it out on my students. I taught them to use the annotation app, Hypothesis, and assigned them to highlight and comment on the chapters each week in preparation for class discussions. This had the dual benefits of engaging them with the content, and also indicating to me which parts of the text were working well and which needed improvement. Since I wasn't telling them what they had to highlight and respond to, I was able to see what elements caught students attention and interest. And possibly more important, I was able to "mind the gaps', and rework parts that were too confusing or too boring to get the attention I thought they deserved.

      This is an intriguing off-label use case for Hypothes.is which is within the realm of peer-review use cases.

      Dan is essentially using the idea of annotation as engagement within a textbook as a means of proactively improving it. He's mentioned it before in Hypothes.is Social (and Private) Annotation.

      Because one can actively see the gaps without readers necessarily being aware of their "review", this may be a far better method than asking for active reviews of materials.

      Reviewers are probably not as likely to actively mark sections they don't find engaging. Has anyone done research on this space for better improving texts? Certainly annotation provides a means for helping to do this.

  21. Mar 2022
    1. The Inca are most often remembered not for what they had but for what they didn’t have: the wheel, iron, a written language.

      A solid example of how western cultures dismiss non-literate cultures.

  22. Jan 2022
    1. Still, persuasiveness need not take the form of logicalargumentation; it can just as easily involve appeal to sentiment,whipping up passions, deploying poetic metaphors, appealing tomyth or proverbial wisdom, employing irony and indirection, humour,insult, or appeals to prophecy or revelation; and the degree to whichone privileges any of these has everything to do with the rhetoricaltradition to which the speaker belongs, and the presumeddispositions of their audience.

      A list of means of persuasiveness:

      • use of logical argumentation
      • appeal to sentiment
      • whipping up passions
      • deploying poetic metaphors
      • appeal to mythology, proverbial or ancient wisdom
      • irony
      • indirection
      • humor
      • insult
      • prophecy/revelation
      • appeal to the rhetorical tradition to which the speaker belongs (pathos, ethos, etc.)
      • presumed disposition of the audience

      What others are there?

      Certainly Donald Trump didn't use logical argumentation. He didn't even frame things as being for something so much as being against other things.

  23. Oct 2021
    1. But first, a word of caution. Writing affirmations is a good way to manage stressful situations and mitigate negative thoughts for many people. However, for people with low self-esteem or depression, studies suggest that self-affirmation can be harmful. Repeating a statement that you do not believe to be true can make you feel worse. In circumstances where self-affirmations could do harm, it is more appropriate to invest in support from a therapist or counsellor.

      Our emotional state is a magnet for what we accent or believe, if we're positive we believe the positive and if we're negative we look for confirmation for that state. Maybe our emotious is our boss?

  24. Sep 2021
  25. Aug 2021
    1. Many of the snippets here talk about what was in individual commonplace books and how their contents indicated what was admired. What about the negative image of all the things which were excluded?

      What things did people read which they didn't commonplace? What does that say about them? Their times? The way they thought?

      Could their commonplacing be compared with their marginalia to show what rose to certain levels of interest and what didn't? Digging through the records to find and verify marginalia may be incredibly tedious in comparison with specifically kept things.

      Some of my own fleeting notes, which I keep because it's easy, may show some interesting things about the way I think in comparison to those things upon which I expand, keep, and value more for my work and my worldview.

  26. Jul 2021
    1. As I wrote in January, silence is effectively impossible on the contemporary internet, where “voids are just filled by other people’s content, and thus vanish instantly.”

      Where are the empty spaces on the internet? How can we design them into existence?

  27. Jun 2021
    1. We just cannot know all that life will throw at us, and if we want our grading contract to be fair and equitable for everyone, we need to reexamine it, reflect on how it has been working for each of us, and perhaps adjust it. 

      This idea of re-evaluating at regular time points can be a very useful and powerful tool in more areas than just writing.

      Society as a whole needs to look carefully at where it is do do this same sort of readjustment as well.

      It's the same sort of negative feedback mechanism which is at work in the scientific method and constantly improving the state-of-the art.

  28. May 2021
    1. Dr Zoë Hyde. (2021, February 23). I don’t like to dwell on negatives, but something important happened recently that I’d like to make public. Shortly before Christmas, @mugecevik made a complaint to my university about me. When asked for details, she didn’t provide any. My employer took a dim view of the matter. [Tweet]. @DrZoeHyde. https://twitter.com/DrZoeHyde/status/1364184623262048259

    1. Negative values are mostly unsupported in html email. So is CSS position. For webmail at least, this is so that your email doesn't render outside of the desired window. Imagine Gmail with your CSS or email affecting the interface - they've limited the CSS you can use specifically to prevent this.
  29. Apr 2021
    1. No, I'm afraid not. I wanted to like it, but it hasn't offered up anything to make me choose this over a wealth of other short two-player games. It should go without saying (but it's worth repeating in view of the responses such reviews tend to get on BGG) that a negative review is always subjective and personal to the reviewer.
    1. The areas which were most improved by exercising were patients' ability to understand social situations, their attention spans, and their 'working memory'

      That is an interesting set of improvements. These are negative symptoms that are resolved, which is largely what I'd expect. I'd bet there is some effect on positive symptoms too, but with low certainty. Moreover, these results are excellent in that negative symptoms are the hardest to treat.

  30. Mar 2021
    1. David Leonhardt. (2021, February 19). - About 1/3 of military troops who’ve been offered vaccine shots have declined. - When shots became available to Ohio nursing-home workers, 60% said no. - Among frontline workers in SoCal, the share was 40-50%. - N.B.A. stars are wary of doing public-services ads. (2/x) [Tweet]. @DLeonhardt. https://twitter.com/DLeonhardt/status/1362768083899793413

  31. psycnet-apa-org.lib-ezproxy.concordia.ca psycnet-apa-org.lib-ezproxy.concordia.ca
    1. Both higher levels of reported stress and theperception that stress affects health were independently associated with an increased likelihood of worsehealth and mental health outcomes. The amount of stress and the perception that stress affects healthinteracted such that those who reported a lot of stress and that stress impacted their health a lot had a 43%increased risk of premature death (HR1.43, 95% CI [1.2, 1.7])

      Căng thẳng ảnh hưởng xấu gia tăng nguy cơ tử vong

    1. He introduces the idea of the apophatic: what we can't put into words, but is important and vaguely understood. This term comes from Orthodox theology, where people defined god by saying what it was not.

      Too often as humans we're focused on what is immediately in front of us and not what is missing.

      This same thing plagues our science in that we're only publishing positive results and not negative results.

      From an information theoretic perspective, we're throwing away half (or more?) of the information we're generating. We might be able to go much farther much faster if we were keeping and publishing all of our results in better fashion.

      Is there a better word for this negative information? #openquestions

  32. Feb 2021
    1. Help defend Monica from defamation! Stack Overflow, Inc. must repair the damage caused by their libel against Monica Cellio, cooperate with the community, be willing to talk, treat users with respect, learn about the world outside the United States, open the governance of the sites.
  33. Jan 2021
  34. Dec 2020
  35. Nov 2020
    1. The success of JSX has proved that the second curly is unnecessary. Moreover, a lot of people — particularly those who have been exposed to React — have a visceral negative reaction to double curlies, many of them assuming that it brings with it all the limitations of crusty old languages like Mustache and Handlebars, where you can't use arbitrary JavaScript in expressions.
  36. Oct 2020
    1. Weber notes that according to any economic theory that posited man as a rational profit-maximizer, raising the piece-work rate should increase labor productivity. But in fact, in many traditional peasant communities, raising the piece-work rate actually had the opposite effect of lowering labor productivity: at the higher rate, a peasant accustomed to earning two and one-half marks per day found he could earn the same amount by working less, and did so because he valued leisure more than income. The choices of leisure over income, or of the militaristic life of the Spartan hoplite over the wealth of the Athenian trader, or even the ascetic life of the early capitalist entrepreneur over that of a traditional leisured aristocrat, cannot possibly be explained by the impersonal working of material forces,

      Science could learn something from this. Science is too far focused on the idealized positive outcomes that it isn't paying attention to the negative outcomes and using that to better define its outline or overall shape. We need to define a scientific opportunity cost and apply it to the negative side of research to better understand and define what we're searching for.

      Of course, how can we define a new scientific method (or amend/extend it) to better take into account negative results--particularly in an age when so many results aren't even reproducible?

  37. Sep 2020
    1. The origin of these commandments follows the law of negative entities impressing information upon positively oriented mind/body/spirit complexes.

      Think about this "law". The law of negative entities is impressing information upon positively oriented beings. Interesting. Think of the old game, "Don't think of an elephant"

  38. Aug 2020
    1. This means that while groups can generate high levels of solidarity, which can in principle be put to powerful political effect, it also becomes harder to express disagreement within the group. If, for example, an outspoken and popular member of a neighbourhood WhatsApp group begins to circulate misinformation about health risks, the general urge to maintain solidarity means that their messages are likely to be met with approval and thanks. When a claim or piece of content shows up in a group, there may be many members who view it as dubious; the question is whether they have the confidence to say as much. Meanwhile, the less sceptical can simply forward it on. It’s not hard, then, to understand why WhatsApp is a powerful distributor of “fake news” and conspiracy theories.

      Instead of positive feedback like this, is there a way to create negative feedback loops in these social media apps?

  39. Jul 2020
  40. Jun 2020
  41. May 2020
  42. Apr 2020
  43. Feb 2020
    1. Denn wer nicht dauergrinst, sondern sich mit seinen unangenehmen Gefühlen auseinandersetzt, tut seiner Psyche etwas Gutes. Das zeigen Studien von James Pennebaker, einem Psychologen an der University of Texas in Austin. Die Konfrontation mit dem Negativen solle schriftlich geschehen, rät Pennebaker. Er nennt es "expressives Schreiben". In zahlreichen Experimenten hat er festgestellt, dass dieses Schreiben, wenn es regelmäßig geschieht, Menschen nicht nur bei der Bewältigung ihrer negativen Emotionen helfen, sondern auch ihr Wohlbefinden fördern kann - und zwar langfristig.
  44. Jan 2020
  45. Nov 2019
    1. To avoid the pursuit of unproductive paths, we report here what has not worked in our hands, as well as our progress developing a method to screen the most efficient electroporation parameters for optimal DNA delivery into Prochlorococcus cells

      negative results

  46. Oct 2019
  47. Sep 2019
  48. Apr 2019
    1. Complying with these various laws could cause us to incur substantial costs or require us to change our business practices in a manner adverse to our business.
    2. Our business is subject to complex and rapidly evolving U.S. and international laws and regulations regarding privacy and data protection. Many of these laws and regulations are subject to change and uncertain interpretation and could result in claims, changes to our business practices, penalties, increased cost of operations, or declines in user growth or engagement, or otherwise harm our business.
    3. Technologies have been developed to make customizable ads more difficult or to block the display of ads altogether and some providers of online services have integrated technologies that could potentially impair the core functionality of third-party digital advertising. Most of our Google revenues are derived from fees paid to us in connection with the display of ads online. As a result, such technologies and tools could adversely affect our operating results.
    4. A number of our Other Bets initiatives are in their initial development stages, and as such, the sources of revenues from these businesses could change over time and the revenues could be volatile.
    5. We generate our advertising revenues increasingly from mobile and newer advertising formats, and the margins from the advertising revenues from these sources have generally been lower than those from traditional desktop search. Accordingly, we expect TAC paid to our distribution partners to increase due to changes in device mix between mobile, desktop, and tablet, partner mix, partner agreement terms, and the percentage of queries channeled through paid access points. We expect these trends to continue to put pressure on our overall margins.
    6. Programmatic buying has a different monetization profile than traditional advertising buying on Google properties
    7. Similarly, the Directive on Copyright in the Digital Single Market (DSM) in Europe, if passed in its proposed form, will increase the liability of large hosted platforms with respect to content uploaded by their users. It will also create a new property right in news publications that will limit the ability of online services to interact with or present such content.
    8. Our revenue growth rate could decline over time, and we anticipate downward pressure on our operating margin in the future.
    9. We and other companies in the technology industry have experienced increased regulatory scrutiny recently. For instance, various regulatory agencies are reviewing aspects of our search and other businesses.
    10. In addition, new products and services, including those that incorporate or utilize artificial intelligence and machine learning, can raise new or exacerbate existing ethical, technological, legal, and other challenges, which may negatively affect our brands and demand for our products and services and adversely affect our revenues and operating results.
    11. If we do not continue to innovate and provide products and services that are useful to users, we may not remain competitive, and our revenues and operating results could be adversely affected.
    12. Competition for qualified personnel in our industry is intense, particularly for software engineers, computer scientists, and other technical staff.
    13. We face formidable competition in every aspect of our business, particularly from companies that seek to connect people with online information and provide them with relevant advertising.
  49. Mar 2018
    1. Con-servative strategies (15) serve individual careerswell but are less effective for science as a whole.Such strategies are amplified by the file drawerproblem (16): Negative results, at odds withestablished hypotheses, are rarely published,leadingto a systemic bias in published researchand the canonization of weak and sometimesfalse facts (17). More risky hypotheses may havebeen tested by generations of scientists, but onlythose successful enough to result in publicationsare known to us.

      cc @Lepou

  50. Jan 2018
  51. doc-0g-c0-docs.googleusercontent.com doc-0g-c0-docs.googleusercontent.com
    1. Reinstates the classification of mobile broadband Internet access service as a private mobile service.

      Internet used on the phone will be charged as a service fee because they are consuming more of it than other people.

  52. Sep 2017
    1. the term “trump” indicates positive feeling, something which is likely no longer true for a sizable number of Americans.

      How can these technologies account for these linguistic contingencies?

  53. Mar 2017
    1. oil and gas exploration in and around the Beaufort Sea concerns the people who live there, because they depend on the fish, seals, whales and polar bears for which the Beaufort Sea is vital habitat.

      As the ecological impact of the region is considered, it is worthy to note the group consciousness that the Alaskan natives experienced with regards to this risk. The heightened awareness of this ecological impact on the region became evident in the political activism and energy behind these local communities in the decade leading up to the project proposal. With the expanding presence of oil and gas extractive companies in the Northern Yukon and surrounding territories, a strong negative externality was exerted onto “fur-bearing creatures” and the resulting trapping lifestyle of the indigenous communities. Furthermore, the integrity of the region’s permafrost became comprised with the widespread and often times ill-measured construction of roads and conduct of industrial activity. Finally, the studied biodiversity of the Arctic region indicated that the ecosystem proved to be particularly vulnerable to the impacts of manmade industrial activity. These elements of vulnerability and danger to the Arctic region contributed to the notion that its ecosystem had become decidedly “disturbed” by the impacts of industrial development. This collective experience of a disturbed ecosystem led to the emergence of political activist groups such as Inupiat Paitot (or the “peoples heritage”), a political organization with the mission to serve all Alaskan natives against the external pressures of the oil and gas industries. As the development of a group consciousness among Alaskan natives grew, and subsequent grassroots organizations began to take on the political cause in the Arctic, national and international efforts to confront environmental science were simultaneously becoming a formalized and mainstream effort within into policy-making and industrial project consideration. Upon the initial arrival of the Mackenzie Valley Pipeline Inquiry in 1974, the stage was set for a grassroots movement against the project. In defense of an ecosystem at severe risk of damage, Alaskan natives now possessed the political and social capital necessary to bring about a concerted effort to preserve the region’s resources as well as the self-determination of indigenous communities.

      Stuhl, Andrew. Unfreezing The Arctic: Science, Colonialism, and the Transformation of Inuit Lands. Chicago, IL: The University of Chicago Press, 2016.

  54. Jun 2016
    1. Our results suggest, as some critics argue (Holt, 1964; Sil- berman, 1970), that the information routinely given in schools -- that is, grades -- may encourage an emphasis on quanti- tative aspects of learning, depress creativity, foster fear of failure, and undermine interest. They also suggest that no such negative results ensue from the use of task-related individual- ized comments.

      Good quotation on the negative aspect of grades.

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    Annotators

  55. Jul 2015
    1. n contrast to our initial hypothesis, the genetic deletion of HDAC6 did not reduce the weight loss or the deficits in cognitive abilities and nest-building behavior shown by R6/1 mice, and even worsened their social impairments, hypolocomotion in the Y-maze, and reduced ultrasonic vocalizations.
  56. May 2015
    1. “Unfortunately, I couldn’t find the effect,” he said. “But the worst part was that when I submitted these null results I had difficulty getting them published.

      Important point to make again in the proposal as to why negative results are difficult to publish

  57. Apr 2015
    1. Why sully a CV with papers from the ‘Journal of Failed Experiments’? Don’t we want our colleagues (and especially our competitors) to believe that we succeed at every undertaking?

      Same reason pharma hates the term: Failed drugs

    2. Thus, although the arguments in favor of small-unit publishing all seem to revolve around benefits to the community, the costs of generating these small units would fall on individual authors. If the community is to reap the benefits, then the costs to the individual authors must be driven to zero – or associated with some reward.

      Will they do it?

    3. Time spent publishing small papers is time not spent developing big ones
    4. but because journal editors are obsessively vigilant about rejecting papers that fall below a threshold of ‘novelty’, these papers become unpublishable in practical terms

      The Inglefinger rule.

  58. Nov 2013
    1. Deception, flattering, lying, deluding, talking behind the back, putting up a false front, living in borrowed splendor, wearing a mask, hiding behind convention, playing a role for others and for oneself-in short, a continuous fluttering around the solitary flame of vanity-is so much the rule and the law among men that there is almost nothing which is less comprehensible than how an honest and pure drive for truth could have arisen among them.

      Nietzsche is quick to point out extreme human flaws. Negative nancy. Really sets the tone for the reading, very dark.

  59. Sep 2013
    1. I maintain also that if you compare me with those who profess54 to turn men to a life of temperance and justice, you will find that my teaching is more true and more profitable than theirs. For they exhort their followers to a kind of virtue and wisdom which is ignored by the rest of the world and is disputed among themselves; I, to a kind which is recognized by all. They, again, are satisfied if through the prestige of their names they can draw a number of pupils into their society; I, you will find, have never invited any person to follow me, but endeavor to persuade the whole state to pursue a policy from which the Athenians will become prosperous themselves, and at the same time deliver the rest of the Hellenes from their present ills.

      Works through a negative opposition here and several other places. What might we think of this style? What does it offer?