8,865 Matching Annotations
  1. Oct 2021
    1. Wenzel, J., Lampe, J., Müller-Fielitz, H., Schuster, R., Zille, M., Müller, K., Krohn, M., Körbelin, J., Zhang, L., Özorhan, Ü., Neve, V., Wagner, J. U. G., Bojkova, D., Shumliakivska, M., Jiang, Y., Fähnrich, A., Ott, F., Sencio, V., Robil, C., … Schwaninger, M. (2021). The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells. Nature Neuroscience, 1–12. https://doi.org/10.1038/s41593-021-00926-1

    1. Siddle, K. J., Krasilnikova, L. A., Moreno, G. K., Schaffner, S. F., Vostok, J., Fitzgerald, N. A., Lemieux, J. E., Barkas, N., Loreth, C., Specht, I., Tomkins-Tinch, C. H., Silbert, J., Schaeffer, B., Taylor, B. P., Loftness, B., Johnson, H., Schubert, P. L., Shephard, H. M., Doucette, M., … Sabeti, P. C. (2021). Evidence of transmission from fully vaccinated individuals in a large outbreak of the SARS-CoV-2 Delta variant in Provincetown, Massachusetts (p. 2021.10.20.21265137). https://doi.org/10.1101/2021.10.20.21265137

    1. Mlcochova, P., Kemp, S. A., Dhar, M. S., Papa, G., Meng, B., Ferreira, I. A. T. M., Datir, R., Collier, D. A., Albecka, A., Singh, S., Pandey, R., Brown, J., Zhou, J., Goonawardane, N., Mishra, S., Whittaker, C., Mellan, T., Marwal, R., Datta, M., … Gupta, R. K. (2021). SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion. Nature, 1–6. https://doi.org/10.1038/s41586-021-03944-y

    1. “I just worry that we haven’t clearly defined what the goal” is, said Dr. Paul Offit, an infectious disease expert with the Children’s Hospital of Philadelphia.

      Like this.

    1. Reports of death after COVID-19 vaccination are rare. More than 396 million doses of COVID-19 vaccines were administered in the United States from December 14, 2020, through October 4, 2021. During this time, VAERS received 8,390 reports of death (0.0021%) among people who received a COVID-19 vaccine. FDA requires healthcare providers to report any death after COVID-19 vaccination to VAERS, even if it’s unclear whether the vaccine was the cause. Reports of adverse events to VAERS following vaccination, including deaths, do not necessarily mean that a vaccine caused a health problem. A review of available clinical information, including death certificates, autopsy, and medical records, has not established a causal link to COVID-19 vaccines. However, recent reports indicate a plausible causal relationship between the J&J/Janssen COVID-19 Vaccine and TTS, a rare and serious adverse event—blood clots with low platelets—which has caused deaths pdf icon[1.4 MB, 40 pages].
    1. Magusali, N., Graham, A. C., Piers, T. M., Panichnantakul, P., Yaman, U., Shoai, M., Reynolds, R. H., Botia, J. A., Brookes, K. J., Guetta-Baranes, T., Bellou, E., Bayram, S., Sokolova, D., Ryten, M., Sala Frigerio, C., Escott-Price, V., Morgan, K., Pocock, J. M., Hardy, J., & Salih, D. A. (2021). A genetic link between risk for Alzheimer’s disease and severe COVID-19 outcomes via the OAS1 gene. Brain, awab337. https://doi.org/10.1093/brain/awab337

    1. Wickenhagen, A., Sugrue, E., Lytras, S., Kuchi, S., Noerenberg, M., Turnbull, M. L., Loney, C., Herder, V., Allan, J., Jarmson, I., Cameron-Ruiz, N., Varjak, M., Pinto, R. M., Lee, J. Y., Iselin, L., Palmalux, N., Stewart, D. G., Swingler, S., Greenwood, E. J. D., … Wilson, S. J. (n.d.). A prenylated dsRNA sensor protects against severe COVID-19. Science, 0(0), eabj3624. https://doi.org/10.1126/science.abj3624

    1. Dr Nisreen Alwan 🌻 on Twitter: “New @ONS #LongCovid estimates published today: 1.1 MILLION (1.7% of the whole UK population). Up from the summer estimate of 1.5%. 211,000 people with daily activities ‘limited a lot’. Greatest % in working age (35-69y). Rising prevalence in 17-24y. A tsunami of chronic illness.” / Twitter. (n.d.). Retrieved October 10, 2021, from https://twitter.com/Dr2NisreenAlwan/status/1446110337753829379

    1. Forbes, H., Morton, C. E., Bacon, S., McDonald, H. I., Minassian, C., Brown, J. P., Rentsch, C. T., Mathur, R., Schultze, A., DeVito, N. J., MacKenna, B., Hulme, W. J., Croker, R., Walker, A. J., Williamson, E. J., Bates, C., Mehrkar, A., Curtis, H. J., Evans, D., … Tomlinson, L. A. (2020). Association between living with children and outcomes from COVID-19: An OpenSAFELY cohort study of 12 million adults in England (p. 2020.11.01.20222315). https://doi.org/10.1101/2020.11.01.20222315

    1. Timothy Caulfield on Twitter: “Will you fall into the conspiracy theory rabbit hole? Https://t.co/8mLQqSBnqb by @databyler @codingyan Good breakdown on some of the social forces (like ideology) that drive conspiracy theories. Despite the fact I study topic, still amazed how many believe this stuff. Https://t.co/L1T0cpy9kB” / Twitter. (n.d.). Retrieved October 8, 2021, from https://twitter.com/CaulfieldTim/status/1445794723101175818

    1. Coronavirus Pandemic Data Explorer. (n.d.). Our World in Data. Retrieved March 3, 2021, from https://ourworldindata.org/coronavirus-data-explorer

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