8,867 Matching Annotations
  1. Mar 2021
    1. Kniffin, K. M., Narayanan, J., Anseel, F., Antonakis, J., Ashford, S., Bakker, A. B., Bamberger, P., Bapuji, H., Bhave, D. P., Choi, V. K., Creary, S. J., Demerouti, E., Flynn, F., Gelfand, Mi., Greer, L., Johns, G., Kesebir, S., Klein, P. G., Lee, S. Y., … van vugt, mark. (2020). COVID-19 and the Workplace: Implications, Issues, and Insights for Future Research and Action [Preprint]. PsyArXiv. https://doi.org/10.31234/osf.io/gkwme

    1. Schlosser, F., Maier, B. F., Hinrichs, D., Zachariae, A., & Brockmann, D. (2020). COVID-19 lockdown induces structural changes in mobility networks—Implication for mitigating disease dynamics. ArXiv:2007.01583 [Physics, q-Bio]. http://arxiv.org/abs/2007.01583

    1. Rosendaal, F. R. (2020). Review of: “Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial Gautret et al 2010, DOI:10.1016/j.ijantimicag.2020.105949. International Journal of Antimicrobial Agents, 106063. https://doi.org/10.1016/j.ijantimicag.2020.106063

    1. Schoch-Spana, M., Brunson, E. K., Long, R., Ruth, A., Ravi, S. J., Trotochaud, M., Borio, L., Brewer, J., Buccina, J., Connell, N., Hall, L. L., Kass, N., Kirkland, A., Koonin, L., Larson, H., Lu, B. F., Omer, S. B., Orenstein, W. A., Poland, G. A., … White, A. (2020). The public’s role in COVID-19 vaccination: Human-centered recommendations to enhance pandemic vaccine awareness, access, and acceptance in the United States. Vaccine. https://doi.org/10.1016/j.vaccine.2020.10.059

    1. Erik Angner. (2021, February 18). Periodic reminder that in terms of outcomes, Swedish corona policy is thoroughly average in EU comparison – not exactly a model to be emulated by the rest of the world, nor a crime against humanity that should be prosecuted in the Hague. Https://t.co/E1CHBFMs6S [Tweet]. @ErikAngner. https://twitter.com/ErikAngner/status/1362319246378872832

    1. Dank der tollen Unterstützung von @TheRealTweetmo , Thomas Traill & Ulrike Hahn gibt es jetzt die deutsche Übersetzung des Anfang Januar erschienenen "COVID-19 Vaccine Communication Handbook" als "Kommunikationshandbuch zum COVID-19-Impfstoff" - https://sks.to/c19vax-de #COVID-19

    1. David Leonhardt. (2021, February 19). - About 1/3 of military troops who’ve been offered vaccine shots have declined. - When shots became available to Ohio nursing-home workers, 60% said no. - Among frontline workers in SoCal, the share was 40-50%. - N.B.A. stars are wary of doing public-services ads. (2/x) [Tweet]. @DLeonhardt. https://twitter.com/DLeonhardt/status/1362768083899793413

    1. ReconfigBehSci. (2020, November 11). RT @EpiCOVIDCorps: The COVID Corps YouTube channel is live! Here’s who we are and what we’re about. New videos every Wednesday. Https://t.c… [Tweet]. @SciBeh. https://twitter.com/SciBeh/status/1326848746093752321

    1. Prof. Devi Sridhar. (2020, March 25). We will be stuck in an endless cycle of lockdown/release for next 18 months, if we do not start mass testing, tracing, & isolating those who are carriers of the virus while pursuing rapid research for antiviral treatment or vaccine. This is the message the public needs to hear. [Tweet]. @devisridhar. https://twitter.com/devisridhar/status/1242743618986745861

    1. Wang, P., Nair, M. S., Liu, L., Iketani, S., Luo, Y., Guo, Y., Wang, M., Yu, J., Zhang, B., Kwong, P. D., Graham, B. S., Mascola, J. R., Chang, J. Y., Yin, M. T., Sobieszczyk, M., Kyratsous, C. A., Shapiro, L., Sheng, Z., Huang, Y., & Ho, D. D. (2021). Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7. Nature, 1–9. https://doi.org/10.1038/s41586-021-03398-2

    1. Ashish K. Jha, MD, MPH. (2020, December 12). Michigan vs. Ohio State Football today postponed due to COVID But a comparison of MI vs OH on COVID is useful Why? While vaccines are coming, we have 6-8 hard weeks ahead And the big question is—Can we do anything to save lives? Lets look at MI, OH for insights Thread [Tweet]. @ashishkjha. https://twitter.com/ashishkjha/status/1337786831065264128

    1. Ghio, D., Lawes-Wickwar, S., Tang, M. Y., Epton, T., Howlett, N., Jenkinson, E., Stanescu, S., Westbrook, J., Kassianos, A., Watson, D., Sutherland, L., Stanulewicz, N., Guest, E., Scanlan, D., Carr, N., Chater, A., Hotham, S., Thorneloe, R., Armitage, C., … Keyworth, C. (2020). What influences people’s responses to public health messages for managing risks and preventing infectious diseases? A rapid systematic review of the evidence and recommendations [Preprint]. PsyArXiv. https://doi.org/10.31234/osf.io/nz7tr

    1. Results for individual PALB2 variants were normalized relative to WT-PALB2 and the p.Tyr551ter (p.Y551X) truncating variant on a 1:5 scale with the fold change in GFP-positive cells for WT set at 5.0 and fold change GFP-positive cells for p.Y551X set at 1.0. The p.L24S (c.71T>C), p.L35P (c.104T>C), p.I944N (c.2831T>A), and p.L1070P (c.3209T>C) variants and all protein-truncating frame-shift and deletion variants tested were deficient in HDR activity, with normalized fold change <2.0 (approximately 40% activity) (Fig. 1a).

      AssayResult: 5.2

      AssayResultAssertion: Normal

      StandardErrorMean: 0.33

    2. A total of 84 PALB2 patient-derived missense variants reported in ClinVar, COSMIC, and the PALB2 LOVD database were selected

      HGVS: NM_024675.3:c.1732A>G p.(Ser578Gly)

    1. SUPPLEMENTARY DATA

      AssayResult: 97.77

      AssayResultAssertion: Not reported

      PValue: > 0.9999

      Comment: Exact values reported in Table S3.

    2. To this end, 44 missense variants found in breast cancer patients were identified in the ClinVar database (https://www.ncbi.nlm.nih.gov/clinvar) and/or selected by literature curation based on their frequency of description or amino acid substitution position in the protein (Supplemental Table S1).

      HGVS: NM_024675.3:c.3049G>A p.(Ala1017Thr)

    1. Source Data

      AssayResult: 78.2

      AssayResultAssertion: Not reported

      ReplicateCount: 2

      StandardErrorMean: 7.31

      Comment: Exact values reported in “Source Data” file.

    2. Source Data

      AssayResult: 87.35

      AssayResultAssertion: Not reported

      ReplicateCount: 2

      StandardDeviation: 11.94

      StandardErrorMean: 8.44

      Comment: Exact values reported in “Source Data” file.

    3. We, therefore, analyzed the effect of 48 PALB2 VUS (Fig. 2a, blue) and one synthetic missense variant (p.A1025R) (Fig. 2a, purple)29 on PALB2 function in HR.

      HGVS: NM_024675.3:c.2117C>T p.(T706I)

    1. Most Suspected Brugada Syndrome Variants Had (Partial) Loss of Function

      AssayResult: 120.5

      AssayResultAssertion: Normal

      ReplicateCount: 41

      StandardErrorMean: 10.5

      Comment: This variant had normal function (75-125% of wildtype peak current, <1% late current, no large perturbations to other parameters). These in vitro features are consistent with non-disease causing variants. (Personal communication: A. Glazer)

    2. we selected 73 previously unstudied variants: 63 suspected Brugada syndrome variants and 10 suspected benign variants

      HGVS: NM_198056.2:c.2317C>T p.(Pro773Ser)

    1. James Hamblin. (2021, March 17). Whenever you vaccinate millions and millions of people, some will inevitably die shortly after. Others will get blood clots. Others will crash cars, or fall down stairs. None of this is newsworthy until there’s reason to believe these things are connected. [Tweet]. @jameshamblin. https://twitter.com/jameshamblin/status/1371993047261667329

    1. ReconfigBehSci. ‘RT @ashishkjha: Over Past Week We Got 11.4 Million Doses into Arms 5.6 Million Were 1st Doses 5.8 Million Were 2nd Doses That’s a Proble…’. Tweet. @SciBeh (blog), 1 March 2021. https://twitter.com/SciBeh/status/1366421544495382533.

    1. Dominic Minghella. ‘Wow. SAGE Scientist Prof Andrew Hayward on Newsnight Unequivocal: “I Won’t Be Getting My Family Together for Christmas.” Young People and Old People Together a Recipe for Disaster/Snatching Defeat from Jaws of Victory/Wait till Easter and Have a Proper Get-Together. #Newsnight’. Tweet. @DMinghella (blog), 25 November 2020. https://twitter.com/DMinghella/status/1331374249001578497.

    1. ♿🏳️‍🌈💙Jack Monroe (they/she). ‘I’m Getting Individual Permission from Everyone Sending Me Pics of Their Food Boxes in My DMs to Repost Them Here but without Identifying Information Because I Try to Be Responsible with This Large Platform and There Are ~children~ Involved Here. Disclaimer Done, Now Get Angry.’ Tweet. @BootstrapCook (blog), 12 January 2021. https://twitter.com/BootstrapCook/status/1348917929132367872.

    2. ♿🏳️‍🌈💙Jack Monroe (they/she). ‘I’m Getting Individual Permission from Everyone Sending Me Pics of Their Food Boxes in My DMs to Repost Them Here but without Identifying Information Because I Try to Be Responsible with This Large Platform and There Are ~children~ Involved Here. Disclaimer Done, Now Get Angry.’ Tweet. @BootstrapCook (blog), 12 January 2021. https://twitter.com/BootstrapCook/status/1348917929132367872.

    1. Brian Stelter. ‘One Year Ago Tonight, in Front of Millions of Loyal Viewers, Fox’s @SeanHannity Accused the Media of “Scaring the Living Hell out of People” about the Coronavirus and Said “I See It, Again, as like, Let’s Bludgeon Trump with This New Hoax.”’ Tweet. @brianstelter (blog), 10 March 2021. https://twitter.com/brianstelter/status/1369460806367199232.

    1. Prado-Vivar, Belén, Mónica Becerra-Wong, Juan José Guadalupe, Sully Márquez, Bernardo Gutierrez, Patricio Rojas-Silva, Michelle Grunauer, Gabriel Trueba, Verónica Barragán, and Paúl Cárdenas. ‘A Case of SARS-CoV-2 Reinfection in Ecuador’. The Lancet Infectious Diseases 0, no. 0 (23 November 2020). https://doi.org/10.1016/S1473-3099(20)30910-5.

    1. Kevin McConway. ‘Media: Worst Ever Week for Test & Trace; They Only Reached 59.9% of Identified Contacts. But the % Reached Went up This Week for Contacts Managed by Local Health Protection Teams AND for Contacts Not Managed by Them (What Used to Be Called “complex” and “Non-Complex” Cases.) How?’ Tweet. @kjm2 (blog), 5 November 2020. https://twitter.com/kjm2/status/1324417367477264386.

    1. Tim Colbourn. ‘7-Day Moving Average for #CovidUK Deaths Is Now 200 Deaths per Day. That’s 1400 Deaths in the Last Week. In Sep When CSA Vallance Said We Need to Stop Increase to Avoid “200 Deaths per Day in Nov” Many Doubted/Mocked Him as a “Scaremonger”. Deaths Still Rising & Not in Nov Yet..’ Tweet. @timcolbourn (blog), 28 October 2020. https://twitter.com/timcolbourn/status/1321231842121494530.

    1. The Lancet Infectious Diseases. ‘Follow the Link Https://T.Co/YSCE9FC88K to Watch a Recording of the Recent Seminar by @JohnSMcConnell, Editor of @TheLancetInfDis -- “#COVID-19: Reality and Misinformation”’. Tweet. @TheLancetInfDis (blog), 2 November 2020. https://twitter.com/TheLancetInfDis/status/1323319489753206786.